-
1
-
-
0028270667
-
Pattern formation in the vertebrate neural plate
-
Ruiz i Altaba A: Pattern formation in the vertebrate neural plate. Trends Neurosci 1994, 17:233-243.
-
(1994)
Trends Neurosci
, vol.17
, pp. 233-243
-
-
Ruiz I Altaba, A.1
-
2
-
-
0027263759
-
Induction of the Xenopus organizer: Expression and regulation of Xnot, a novel FGF and activin-regulated homeobox gene
-
Von Dassow G, Schmidt JE, Kimelman D: Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeobox gene. Genes Dev 1993, 7:355-366.
-
(1993)
Genes Dev
, vol.7
, pp. 355-366
-
-
Von Dassow, G.1
Schmidt, J.E.2
Kimelman, D.3
-
3
-
-
0028955641
-
A homeobox gene involved in node, notochord and neural plate formation of chick embryos
-
Stein S, Kessel M: A homeobox gene involved in node, notochord and neural plate formation of chick embryos. Mech Dev 1995, 49:37-48.
-
(1995)
Mech Dev
, vol.49
, pp. 37-48
-
-
Stein, S.1
Kessel, M.2
-
4
-
-
0029082929
-
Targeted mutation of the murine goosecoid gene results in cranlofacial defects and neonatal death
-
Yamada G, Mansouri A, Torres M, Stuart ET, Blum M, Schultz M, De Robertis EM, Gruss P: Targeted mutation of the murine goosecoid gene results in cranlofacial defects and neonatal death. Development 1995, 121:2917-2922.
-
(1995)
Development
, vol.121
, pp. 2917-2922
-
-
Yamada, G.1
Mansouri, A.2
Torres, M.3
Stuart, E.T.4
Blum, M.5
Schultz, M.6
De Robertis, E.M.7
Gruss, P.8
-
5
-
-
0029124998
-
Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development
-
Rivera-Pérez JA, Mallo M, Gendron-Maguire M, Gridley T, Behringer RR: goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development Development 1995, 121:3005-3012.
-
(1995)
Development
, vol.121
, pp. 3005-3012
-
-
Rivera-Pérez, J.A.1
Mallo, M.2
Gendron-Maguire, M.3
Gridley, T.4
Behringer, R.R.5
-
6
-
-
0028169992
-
HNF-3 beta is essential for node and notochord formation in mouse development
-
Ang SL, Rossant J: HNF-3 beta is essential for node and notochord formation in mouse development. Cell 1994, 78:561-574. Targeted disruption of the HNF-3β gene yields embryos that have neither a node nor a notochord. Remarkably, these mutant embryos exhibit relatively normal A/P patterning of the neuraxis.
-
(1994)
Cell
, vol.78
, pp. 561-574
-
-
Ang, S.L.1
Rossant, J.2
-
7
-
-
0028025566
-
The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo
-
••], this paper focuses more on the consequences of notochord and floor plate loss for development of the neural tube.
-
(1994)
Cell
, vol.78
, pp. 575-588
-
-
Weinstein, D.C.1
Ruiz I Altaba, A.2
Chen, W.S.3
Hoodless, P.4
Prezioso, V.R.5
Jessell, T.M.6
Darnell J.E., Jr.7
-
8
-
-
0028905544
-
Requirement for Lim1 in head-organizer function
-
Shawlot W, Behringer RR: Requirement for Lim1 in head-organizer function. Nature 1995, 374:425-430. A report of the embryonic phenotype resulting from targeted disruption of the Lim-1 gene in mice. Embryos homozygous null for the Lim-1 gene lack anterior head structures, exhibiting a truncation of the CNS at the level of rhombomere three; yet, what remains of their body axes develops normally.
-
(1995)
Nature
, vol.374
, pp. 425-430
-
-
Shawlot, W.1
Behringer, R.R.2
-
9
-
-
0027220676
-
The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm
-
Izpisua-Belmonte JC, De Robertis EM, Storey KG, Stern CD: The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm. Cell 1993, 74:645-659.
-
(1993)
Cell
, vol.74
, pp. 645-659
-
-
Izpisua-Belmonte, J.C.1
De Robertis, E.M.2
Storey, K.G.3
Stern, C.D.4
-
10
-
-
0026342562
-
Molecular nature of Spemann's organizer: The role of the Xenopus homeobox gene goosecoid
-
Cho KW, Blumberg B, Steinbeisser H, De Robertis EM: Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 1991, 67:1111-1120.
-
(1991)
Cell
, vol.67
, pp. 1111-1120
-
-
Cho, K.W.1
Blumberg, B.2
Steinbeisser, H.3
De Robertis, E.M.4
-
11
-
-
0028178788
-
HNF-3 beta as a regulator of floor plate development
-
Sasaki H, Hogan BL: HNF-3 beta as a regulator of floor plate development. Cell 1994, 76:103-115. Ectopic expression of HNF-3β in the dorsal mid-hindbrain region of transgenic mice induces an ectopic floor plate.
-
(1994)
Cell
, vol.76
, pp. 103-115
-
-
Sasaki, H.1
Hogan, B.L.2
-
12
-
-
0027182312
-
Midline cells and the organization of the vertebrate neuraxis
-
Ruiz i Altaba A, Jessell TM: Midline cells and the organization of the vertebrate neuraxis. Curr Opin Genet Dev 1993, 3:633-640.
-
(1993)
Curr Opin Genet Dev
, vol.3
, pp. 633-640
-
-
Ruiz I Altaba, A.1
Jessell, T.M.2
-
13
-
-
0027160202
-
Anterior mesendoderm induces mouse Engrailed genes in explant cultures
-
Ang SL, Rossant J: Anterior mesendoderm induces mouse Engrailed genes in explant cultures. Development 1993, 118:139-149.
-
(1993)
Development
, vol.118
, pp. 139-149
-
-
Ang, S.L.1
Rossant, J.2
-
14
-
-
0029059425
-
Induction of epidermis and inhibition of neural fate by Bmp-4
-
Wilson PA, Hemmati-Brivanlou A: Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 1995, 376:331-333. BMP-4 is shown to be a potent epidermal inducer and neural inhibitor in Xenopus animal-cap assays, supporting a model in which neural specification is under inhibitory control.
-
(1995)
Nature
, vol.376
, pp. 331-333
-
-
Wilson, P.A.1
Hemmati-Brivanlou, A.2
-
15
-
-
0029009530
-
Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus
-
Sasai Y, Lu B, Steinbeisser H, De Robertis EM: Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 1995, 376:333-336. Reports that chordin, an organizer-specific secreted protein, can induce neural tissue in Xenopus animal cap assays. Moreover, this activity can be antagonized by BMP-4, providing support for a model in which neural specification is under inhibitory control.
-
(1995)
Nature
, vol.376
, pp. 333-336
-
-
Sasai, Y.1
Lu, B.2
Steinbeisser, H.3
De Robertis, E.M.4
-
16
-
-
0028212942
-
Roads to neuralness: Embryonic neural induction as derepression of a default state
-
Green JB: Roads to neuralness: embryonic neural induction as derepression of a default state. Cell 1994, 77:317-320.
-
(1994)
Cell
, vol.77
, pp. 317-320
-
-
Green, J.B.1
-
17
-
-
0028557131
-
Genetic control of cell fate specification in Drosophila peripheral nervous system
-
Jan YN, Jan LY: Genetic control of cell fate specification in Drosophila peripheral nervous system. Annu Rev Genet 1994, 28:373-393.
-
(1994)
Annu Rev Genet
, vol.28
, pp. 373-393
-
-
Jan, Y.N.1
Jan, L.Y.2
-
18
-
-
0027431778
-
Mechanisms of early neurogenesis in Drosophila melanogaster
-
Campos-Ortega JA: Mechanisms of early neurogenesis in Drosophila melanogaster. J Neurobiol 1993, 24:1305-1327.
-
(1993)
J Neurobiol
, vol.24
, pp. 1305-1327
-
-
Campos-Ortega, J.A.1
-
19
-
-
0024997361
-
Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors
-
Johnson JE, Birren SJ, Anderson DJ: Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors. Nature 1990, 346:858-861.
-
(1990)
Nature
, vol.346
, pp. 858-861
-
-
Johnson, J.E.1
Birren, S.J.2
Anderson, D.J.3
-
20
-
-
0027517354
-
Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system
-
Guillemot F, Joyner AL: Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system. Mech Dev 1993, 42:171-185.
-
(1993)
Mech Dev
, vol.42
, pp. 171-185
-
-
Guillemot, F.1
Joyner, A.L.2
-
21
-
-
0027081439
-
XASH1, a Xenopus homolog of achaete-scute: A proneural gene in anterior regions of the vertebrate CNS
-
Ferreiro B, Skoglund P, Bailey A, Dorsky R, Harris WA: XASH1, a Xenopus homolog of achaete-scute: a proneural gene in anterior regions of the vertebrate CNS. Mech Dev 1993, 40:25-36.
-
(1993)
Mech Dev
, vol.40
, pp. 25-36
-
-
Ferreiro, B.1
Skoglund, P.2
Bailey, A.3
Dorsky, R.4
Harris, W.A.5
-
22
-
-
0029068316
-
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
-
Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, Weintraub H: Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 1995, 268:836-844. Describes the isolation and cloning of Xenopus and mouse neuroD genes, which encode novel bHLH proteins. neuroD is likely to be a neurogenic differentiation factor, based on its transient expression in subsets of post-mitotic neurons in the CNS and peripheral nervous system, as well as its ability to cause premature differentiation of neurons when expressed ectopically.
-
(1995)
Science
, vol.268
, pp. 836-844
-
-
Lee, J.E.1
Hollenberg, S.M.2
Snider, L.3
Turner, D.L.4
Lipnick, N.5
Weintraub, H.6
-
23
-
-
0028306459
-
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
-
••]), regulating the specification of neural or epidermal cell fate. Ectopic expression of Xash-3 results in an expansion of the neural plate, at the expense of surrounding ectoderm, and induction of the Xenopus Notch homolog, Xotch.
-
(1994)
Genes Dev
, vol.8
, pp. 1434-1447
-
-
Turner, D.L.1
Weintraub, H.2
-
24
-
-
0027227967
-
XASH-3, a novel Xenopus achaete-scute homolog, provides an early marker of planar neural induction and position along the mediolateral axis of the neural plate
-
Zimmerman K, Shih J, Bars J, Collazo A, Anderson DJ: XASH-3, a novel Xenopus achaete-scute homolog, provides an early marker of planar neural induction and position along the mediolateral axis of the neural plate. Development 1993, 119:221-232.
-
(1993)
Development
, vol.119
, pp. 221-232
-
-
Zimmerman, K.1
Shih, J.2
Bars, J.3
Collazo, A.4
Anderson, D.J.5
-
25
-
-
0028295171
-
A chicken achaete-scute homolog (CASH-1) is expressed in a temporally and spatially discrete manner in the developing nervous system
-
Jasoni CL, Walker MB, Morris MD, Reh TA: A chicken achaete-scute homolog (CASH-1) is expressed in a temporally and spatially discrete manner in the developing nervous system. Development 1994, 120:769-783. Description of the isolation of Cash-1, a chick homolog of Mash-1. Expression of Cash-1 in the developing retina suggests that it may be involved in defining a particular stage of retinal progenitor development.
-
(1994)
Development
, vol.120
, pp. 769-783
-
-
Jasoni, C.L.1
Walker, M.B.2
Morris, M.D.3
Reh, T.A.4
-
26
-
-
0028966566
-
MATH-2, a mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal, is specifically expressed in the nervous system
-
Shimizu C, Akazawa C, Nakanishi S, Kageyama R: MATH-2, a mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal, is specifically expressed in the nervous system. Eur J Biochem 1995, 229:239-248.
-
(1995)
Eur J Biochem
, vol.229
, pp. 239-248
-
-
Shimizu, C.1
Akazawa, C.2
Nakanishi, S.3
Kageyama, R.4
-
27
-
-
0028903796
-
A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system
-
Akazawa C, Ishibashi M, Shimizu C, Nakanishi S, Kageyama R: A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system. J Biol Chem 1995, 270:8730-8738.
-
(1995)
J Biol Chem
, vol.270
, pp. 8730-8738
-
-
Akazawa, C.1
Ishibashi, M.2
Shimizu, C.3
Nakanishi, S.4
Kageyama, R.5
-
28
-
-
0028961424
-
A transcription factor controlling development of peripheral sense organs in C. elegans
-
Zhao C, Emmons SW: A transcription factor controlling development of peripheral sense organs in C. elegans. Nature 1995, 373:74-78. Cloning of the C. elegans gene lin-32 shows that it encodes a homolog of the Drosophila Achaete-Scute family of transcription factors. Analyses of both loss-of-function and gain-of-function mutant phenotypes demonstrates that lin-32 is necessary, and in some cases sufficient, for specification of neuroblast cell fate.
-
(1995)
Nature
, vol.373
, pp. 74-78
-
-
Zhao, C.1
Emmons, S.W.2
-
29
-
-
0028099362
-
XASH genes promote neurogenesis in Xenopus embryos
-
••], this paper demonstrates that overexpression of Xash-3 or Xash-1 causes expansion of the neural plate, at the expense of epidermis. In addition, it is shown that ectopic expression of Xash-3 in animal caps induces neurogenesis unstably, unless noggin is co-expressed.
-
(1994)
Development
, vol.120
, pp. 3649-3655
-
-
Ferreiro, B.1
Kintner, C.2
Zimmerman, K.3
Anderson, D.4
Harris, W.A.5
-
30
-
-
0027381943
-
Neural induction by the secreted polypeptide noggin
-
Lamb TM, Knecht AK, Smith WC, Stachel SE, Economides AN, Stahl N, Yancopolous GD, Harland RM: Neural induction by the secreted polypeptide noggin. Science 1993, 262:713-718.
-
(1993)
Science
, vol.262
, pp. 713-718
-
-
Lamb, T.M.1
Knecht, A.K.2
Smith, W.C.3
Stachel, S.E.4
Economides, A.N.5
Stahl, N.6
Yancopolous, G.D.7
Harland, R.M.8
-
31
-
-
0026005061
-
Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells
-
Lo LC, Johnson JE, Wuenschell CW, Saito T, Anderson DJ: Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells. Genes Dev 1991, 5:1524-1537.
-
(1991)
Genes Dev
, vol.5
, pp. 1524-1537
-
-
Lo, L.C.1
Johnson, J.E.2
Wuenschell, C.W.3
Saito, T.4
Anderson, D.J.5
-
32
-
-
0027420712
-
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
-
Guillemot F, Lo LC, Johnson JE, Auerbach A, Anderson DJ, Joyner AL: Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell 1993, 75:463-476.
-
(1993)
Cell
, vol.75
, pp. 463-476
-
-
Guillemot, F.1
Lo, L.C.2
Johnson, J.E.3
Auerbach, A.4
Anderson, D.J.5
Joyner, A.L.6
-
33
-
-
0029616735
-
The cellular function of Mash-1 in autonomic neurogenesis
-
-l- mutant neural crest cells are used to understand at what step during autonomic neurogenesis Mash-1 is required. The authors conclude that Mash-1 does not promote neural determination but rather promotes differentiation of an already committed neuronal precursor cell.
-
(1995)
Neuron
, vol.15
, pp. 1245-1258
-
-
Sommer, L.1
Shah, N.2
Rao, M.3
Anderson, D.J.4
-
34
-
-
0025830203
-
Tissue interactions affecting the migration and differentiation of neural crest cells in the chick embryo
-
Stem CD, Artinger KB, Bronner-Fraser M: Tissue interactions affecting the migration and differentiation of neural crest cells in the chick embryo. Development 1991, 113:207-216.
-
(1991)
Development
, vol.113
, pp. 207-216
-
-
Stem, C.D.1
Artinger, K.B.2
Bronner-Fraser, M.3
-
35
-
-
0028915319
-
Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons
-
Groves AK, George KM, Tissier-Seta JP, Engel JD, Brunet JF, Anderson DJ: Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons. Development 1995, 121:887-901. This paper examines expression of the transcription factors Cash-1, Phox-2 and GATA-2 in chick sympathetic ganglia, and shows that expression of Phox-2 and GATA-2 is regulated by notochord signals that control the catecholaminergic phenotype, whereas Cash-1 expression is regulated independently of Phox-2 and GATA-2.
-
(1995)
Development
, vol.121
, pp. 887-901
-
-
Groves, A.K.1
George, K.M.2
Tissier-Seta, J.P.3
Engel, J.D.4
Brunet, J.F.5
Anderson, D.J.6
-
36
-
-
0028009846
-
bHLH factors in muscle development: Dead lines and commitments, what to leave in and what to leave out
-
Olson EN, Klein WH: bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out. Genes Dev 1994, 8:1-8.
-
(1994)
Genes Dev
, vol.8
, pp. 1-8
-
-
Olson, E.N.1
Klein, W.H.2
-
37
-
-
0027135790
-
Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain
-
Schneider-Maunoury S, Topilko P, Seitandou T, Levi G, Cohen-Tannoudji M, Pournin S, Babinet C, Charnay P: Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell 1993, 75:1199-1214.
-
(1993)
Cell
, vol.75
, pp. 1199-1214
-
-
Schneider-Maunoury, S.1
Topilko, P.2
Seitandou, T.3
Levi, G.4
Cohen-Tannoudji, M.5
Pournin, S.6
Babinet, C.7
Charnay, P.8
-
38
-
-
0028600585
-
The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor
-
Cordes SP, Barsh GS: The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell 1994, 79:1025-1034. The discovery of an inversion in an allele of the mouse mutant kreisler (kr) leads to the identification and cloning of the kr gene, which is shown to encode a novel basic-domain leucine zipper transcription factor, and which is expressed in rhombomeres five and six.
-
(1994)
Cell
, vol.79
, pp. 1025-1034
-
-
Cordes, S.P.1
Barsh, G.S.2
-
39
-
-
0027953771
-
Hox genes in vertebrate development
-
Krumlauf R: Hox genes in vertebrate development Cell 1994, 78:191-201.
-
(1994)
Cell
, vol.78
, pp. 191-201
-
-
Krumlauf, R.1
-
40
-
-
0027232546
-
Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries
-
Bulfone A, Puelles L, Porteus MH, Frohman MA, Martin GR, Rubenstein JL: Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J Neurosci 1993, 13:3155-3172.
-
(1993)
J Neurosci
, vol.13
, pp. 3155-3172
-
-
Bulfone, A.1
Puelles, L.2
Porteus, M.H.3
Frohman, M.A.4
Martin, G.R.5
Rubenstein, J.L.6
-
41
-
-
0027171688
-
Segmental organization of embryonic diencephalon
-
Figdor MC, Stern CD: Segmental organization of embryonic diencephalon. Nature 1993, 363:630-634.
-
(1993)
Nature
, vol.363
, pp. 630-634
-
-
Figdor, M.C.1
Stern, C.D.2
-
42
-
-
0027934956
-
Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina
-
Hatini V, Tao W, Lai E: Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina. J Neurobiol 1994, 25:1293-1309.
-
(1994)
J Neurobiol
, vol.25
, pp. 1293-1309
-
-
Hatini, V.1
Tao, W.2
Lai, E.3
-
43
-
-
0027967432
-
Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain
-
Macdonald R, Xu Q, Barth KA, Mikkola I, Holder N, Fjose A, Krauss S, Wilson SW: Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain. Neuron 1994, 13:1039-1053. The boundaries of expression domains of members of the Eph, winged-helix (forkhead), Pax, and Wnt gene families are shown to correlate with the positions at which the earliest neurons in the zebrafish forebrain differentiate.
-
(1994)
Neuron
, vol.13
, pp. 1039-1053
-
-
Macdonald, R.1
Xu, Q.2
Barth, K.A.3
Mikkola, I.4
Holder, N.5
Fjose, A.6
Krauss, S.7
Wilson, S.W.8
-
44
-
-
0028042009
-
Homeobox gene expression during development of the vertebrate brain
-
Rubenstein JL, Puelles L: Homeobox gene expression during development of the vertebrate brain. Curr Top Dev Biol 1994, 29:1-63.
-
(1994)
Curr Top Dev Biol
, vol.29
, pp. 1-63
-
-
Rubenstein, J.L.1
Puelles, L.2
-
45
-
-
0027977029
-
Early CNS development: Distal-less related genes and forebrain development
-
Boncinelli E: Early CNS development: distal-less related genes and forebrain development. Curr Opin Neurobiol 1994, 4:29-36.
-
(1994)
Curr Opin Neurobiol
, vol.4
, pp. 29-36
-
-
Boncinelli, E.1
-
46
-
-
0029009621
-
Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres
-
Xuan S, Baptista CA, Balas G, Tao W, Soares VC, Lai E: Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron 1995, 14:1141-1152. This paper reports the embryonic phenotype resulting from targeted disruption of the BF-1 gene. Homozygotes die shortly after birth and exhibit severe reduction of the cerebral hemispheres. A careful analysis of the underlying bases for the observed telencephalic deletion demonstrates that reduced proliferation, as well as precocious differentiation, leads to depletion of telencephalic precursor cells.
-
(1995)
Neuron
, vol.14
, pp. 1141-1152
-
-
Xuan, S.1
Baptista, C.A.2
Balas, G.3
Tao, W.4
Soares, V.C.5
Lai, E.6
-
47
-
-
0027173427
-
The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head
-
Li J, Vogt PK: The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head. Proc Natl Acad Sci USA 1993, 90:4490-4494.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4490-4494
-
-
Li, J.1
Vogt, P.K.2
-
48
-
-
0029164897
-
Determination events in the nervous system of the vertebrate embryo
-
Bally-Cuif L, Wassef M: Determination events in the nervous system of the vertebrate embryo. Curr Opin Genet Dev 1995, 5:450-458. A comprehensive review of recent progress in understanding specification of the mid-hindbrain boundary.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 450-458
-
-
Bally-Cuif, L.1
Wassef, M.2
-
49
-
-
0026101890
-
Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum
-
Davis CA, Holmyard DP, Millen KJ, Joyner AL: Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development 1991, 111:287-298.
-
(1991)
Development
, vol.111
, pp. 287-298
-
-
Davis, C.A.1
Holmyard, D.P.2
Millen, K.J.3
Joyner, A.L.4
-
50
-
-
0027491553
-
Pax: Gene regulators in the developing nervous system
-
Chalepakis G, Stoykova A, Wijnholds J, Tremblay P, Gruss P: Pax: gene regulators in the developing nervous system. J Neurobiol 1993, 24:1367-1384.
-
(1993)
J Neurobiol
, vol.24
, pp. 1367-1384
-
-
Chalepakis, G.1
Stoykova, A.2
Wijnholds, J.3
Tremblay, P.4
Gruss, P.5
-
51
-
-
0026719855
-
- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
-
- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell 1992, 69:581-595.
-
(1992)
Cell
, vol.69
, pp. 581-595
-
-
McMahon, A.P.1
Joyner, A.L.2
Bradley, A.3
McMahon, J.A.4
-
52
-
-
0029125995
-
Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1
-
Rowitch DH, McMahon AP: Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech Dev 1995, 52:3-8. Careful comparative description of Pax-2, Pax-5, En-1, and Wnt-1 expression at the mid-hindbrain boundary of the early mouse embryo. The data suggest that Pax-2, which is expressed the earliest, acts the furthest upstream in this regulatory hierarchy.
-
(1995)
Mech Dev
, vol.52
, pp. 3-8
-
-
Rowitch, D.H.1
McMahon, A.P.2
-
53
-
-
0025884460
-
Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox
-
Joyner AL, Herrup K, Auerbach BA, Davis CA, Rossant J: Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science 1991, 251:1239-1243.
-
(1991)
Science
, vol.251
, pp. 1239-1243
-
-
Joyner, A.L.1
Herrup, K.2
Auerbach, B.A.3
Davis, C.A.4
Rossant, J.5
-
54
-
-
0027997502
-
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
-
Urbanek P, Wang ZQ, Fetka I, Wagner EF, Busslinger M: Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 1994, 79:901-912. A report on targeted disruption of the Pax-5 gene. Homozygous mutant mice are born, but short-lived. Morphogenesis of the midbrain is abnormal as early as E16.5, leading to reduction of the inferior colliculus, and altered foliation of the anterior cerebellum. Mutants also exhibit an early arrest of B-cell development.
-
(1994)
Cell
, vol.79
, pp. 901-912
-
-
Urbanek, P.1
Wang, Z.Q.2
Fetka, I.3
Wagner, E.F.4
Busslinger, M.5
-
55
-
-
0028325992
-
Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants
-
Millen KJ, Wurst W, Herrup K, Joyner AL: Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants. Development 1994, 120:695-706. In this paper, a follow-up to [53], an additional targeted mutation of the En-2 gene is generated in order to ensure production of a null allele. A detailed analysis of altered cerebellar foliation phenotypes of En-2 null mutants is provided.
-
(1994)
Development
, vol.120
, pp. 695-706
-
-
Millen, K.J.1
Wurst, W.2
Herrup, K.3
Joyner, A.L.4
-
56
-
-
0028310311
-
Multiple developmental defects in Engrailed-1 mutant mice: An early mid-hindbrain deletion and patterning defects in forelimbs and sternum
-
-l- homozygous null mice die shortly after birth, and exhibit deletion of most of the cotliculi and cerebellum, as well as the third and fourth cranial nerves. Mid-hindbrain region deletion is detected as early as E9.5, suggesting that loss of En-1 function causes proliferation defects at the mid-hindbrain boundary.
-
(1994)
Development
, vol.120
, pp. 2065-2075
-
-
Wurst, W.1
Auerbach, A.B.2
Joyner, A.L.3
-
57
-
-
0029059790
-
Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
-
Hanks M, Wurst W, Anson-Cartwright L, Auerbach AB, Joyner AL: Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 1995, 269:679-682. A convincing illustration of the power of the 'knock-in' technique. A targeted replacement of the En-1 gene with En-2 coding sequences is created, and then crossed into an En-1 mutant background, demonstrating that En-2 can rescue En-1 mutant mid-hindbrain defects.
-
(1995)
Science
, vol.269
, pp. 679-682
-
-
Hanks, M.1
Wurst, W.2
Anson-Cartwright, L.3
Auerbach, A.B.4
Joyner, A.L.5
-
58
-
-
0026438292
-
Zebrafish pax[b] is involved in the formation of the midbrain-hindbrain boundary
-
Krauss S, Maden M, Holder N, Wilson SW: Zebrafish pax[b] is involved in the formation of the midbrain-hindbrain boundary. Nature 1992, 360:87-89.
-
(1992)
Nature
, vol.360
, pp. 87-89
-
-
Krauss, S.1
Maden, M.2
Holder, N.3
Wilson, S.W.4
-
59
-
-
0029162584
-
Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
-
Liem KF, Tremml G, Roelink H, Jessell TM: Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 1995, 82:969-979. Demonstrates that BMP-mediated signals from the ectoderm are able to induce expression of a number of dorsally restricted genes in spinal cord explants. In addition, sonic hedgehog can oppose the BMP-mediated dorsalizing signal.
-
(1995)
Cell
, vol.82
, pp. 969-979
-
-
Liem, K.F.1
Tremml, G.2
Roelink, H.3
Jessell, T.M.4
-
60
-
-
0029164902
-
The role of the notochord and floorplate in inductive interactions
-
Placzek M: The role of the notochord and floorplate in inductive interactions. Curr Opin Genet Dev 1995, 5:499-506. An up-to-date review of recent progress towards understanding the roles of the notochord and floor plate in patterning adjacent cells in the neural tube and paraxial mesoderm.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 499-506
-
-
Placzek, M.1
-
61
-
-
0025605289
-
The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system
-
Jostes B, Walther C, Gruss P: The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system. Mech Dev 1990, 33:27-37.
-
(1990)
Mech Dev
, vol.33
, pp. 27-37
-
-
Jostes, B.1
Walther, C.2
Gruss, P.3
-
62
-
-
0027497981
-
Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord
-
Goulding MD, Lumsden A, Gruss P: Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord. Development 1993, 117:1001-1016.
-
(1993)
Development
, vol.117
, pp. 1001-1016
-
-
Goulding, M.D.1
Lumsden, A.2
Gruss, P.3
-
63
-
-
0026638915
-
Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1
-
Ericson J, Thor S, Edlund T, Jessell TM, Yamada T: Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science 1992, 256:1555-1560.
-
(1992)
Science
, vol.256
, pp. 1555-1560
-
-
Ericson, J.1
Thor, S.2
Edlund, T.3
Jessell, T.M.4
Yamada, T.5
-
64
-
-
0027170576
-
Evolution and role of Pax genes
-
Noll M: Evolution and role of Pax genes. Curr Opin Genet Dev 1993, 3:595-605.
-
(1993)
Curr Opin Genet Dev
, vol.3
, pp. 595-605
-
-
Noll, M.1
-
65
-
-
0028216368
-
Ectopic expression of either the Drosophila gooseberry-distal or proximal gene causes alterations of cell fate in the epidermis and central nervous system
-
Zhang Y, Ungar A, Fresquez C, Holmgren R: Ectopic expression of either the Drosophila gooseberry-distal or proximal gene causes alterations of cell fate in the epidermis and central nervous system. Development 1994, 120:1151-1161.
-
(1994)
Development
, vol.120
, pp. 1151-1161
-
-
Zhang, Y.1
Ungar, A.2
Fresquez, C.3
Holmgren, R.4
-
66
-
-
0029113766
-
Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal
-
Skeath JB, Zhang Y, Holmgren R, Carroll SB, Doe CQ: Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal. Nature 1995, 376:427-430. Demonstration that the Drosophila gooseberry genes are necessary and sufficient to specify row 5 neuroblast fate in the embryo.
-
(1995)
Nature
, vol.376
, pp. 427-430
-
-
Skeath, J.B.1
Zhang, Y.2
Holmgren, R.3
Carroll, S.B.4
Doe, C.Q.5
-
67
-
-
0029124995
-
Expression of the unc-4 homeoprotein in Caenorhabditis elegans motor neurons specifies presynaptic input
-
Miller DM, Niemeyer CJ: Expression of the unc-4 homeoprotein in Caenorhabditis elegans motor neurons specifies presynaptic input. Development 1995, 121:2877-2886. Demonstrates that the C. elegans homeobox gene unc-4 confers on a subset of motor neurons the ability to choose the appropriate interneuron synapse.
-
(1995)
Development
, vol.121
, pp. 2877-2886
-
-
Miller, D.M.1
Niemeyer, C.J.2
-
68
-
-
0028568659
-
Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein
-
Jin Y, Hoskins R, Horvitz HR: Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein. Nature 1994, 372:780-783. Demonstrates that the homeobox gene unc-30 is sufficient to induce GABA expression in non-GABAergic neurons.
-
(1994)
Nature
, vol.372
, pp. 780-783
-
-
Jin, Y.1
Hoskins, R.2
Horvitz, H.R.3
-
69
-
-
0027489411
-
The mouse homeodomain protein Phox2 regulates N-CAM promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype
-
Valarche I, Tissier-Seta JP, Hirsch MR, Martinez S, Goridis C, Brunet JF: The mouse homeodomain protein Phox2 regulates N-CAM promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. Development 1993, 119:881-896.
-
(1993)
Development
, vol.119
, pp. 881-896
-
-
Valarche, I.1
Tissier-Seta, J.P.2
Hirsch, M.R.3
Martinez, S.4
Goridis, C.5
Brunet, J.F.6
-
70
-
-
0029583123
-
A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes
-
Zellmer E, Zhang Z, Greco D, Rhodes J, Cassel S, Lewis EJ: A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes. J Neurosci 1995, 15:8109-8120.
-
(1995)
J Neurosci
, vol.15
, pp. 8109-8120
-
-
Zellmer, E.1
Zhang, Z.2
Greco, D.3
Rhodes, J.4
Cassel, S.5
Lewis, E.J.6
-
71
-
-
0028580180
-
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes
-
Tsuchida T, Ensini M, Morton SB, Baldassare M, Edlund T, Jessell TM, Pfaff SL: Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 1994, 79:957-970. Describes the cloning of a family of LIM domain genes in chick, and shows that different combinations of four of these genes are expressed in subclasses of motor neurons that segregate into columns and select distinct axonal pathways to peripheral targets. These findings suggest that these LIM domain proteins may confer on motor neurons the ability to select correct axonal pathways.
-
(1994)
Cell
, vol.79
, pp. 957-970
-
-
Tsuchida, T.1
Ensini, M.2
Morton, S.B.3
Baldassare, M.4
Edlund, T.5
Jessell, T.M.6
Pfaff, S.L.7
-
72
-
-
0029050820
-
Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous
-
Lundgren SE, Callahan CA, Thor S, Thomas JB: Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous. Development 1995, 121:1769-1773. The Drosophila LIM homeodomain protein apterous is shown to be required for a subset of interneurons to choose the correct axonal pathway in the developing embryo. An apterous promoter fusion to an axon targeted reporter, tau-β-galactosidase, is used to follow specific projections.
-
(1995)
Development
, vol.121
, pp. 1769-1773
-
-
Lundgren, S.E.1
Callahan, C.A.2
Thor, S.3
Thomas, J.B.4
-
73
-
-
0029589456
-
Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2
-
-l- mutant embryos revealed that initial cell division and migration of neuronal precursors of the hypothalamus occurs, but hypothalamic neurons fail to express genes encoding neuroregulatory peptides or to make correct axonal projections to the posterior pituitary, and subsequently degenerate.
-
(1995)
Genes Dev
, vol.9
, pp. 3122-3135
-
-
Schonemann, M.D.1
Ryan, A.K.2
McEvilly, R.J.3
O'Connell, S.M.4
Arias, C.A.5
Kalla, K.A.6
Li, P.7
Sawchenko, P.E.8
Rosenfeld, M.G.9
-
74
-
-
13344275857
-
The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse
-
-l- mutant hypothalamic neurons, leading the authors to conclude that in the mutant most neurons fail to successfully migrate into the hypothalamus.
-
(1995)
Genes Dev
, vol.9
, pp. 3109-3121
-
-
Nakai, S.1
Kawano, H.2
Tamaki, Y.3
Nishi, M.4
Kuno, J.5
Nagata, A.6
Jishage, K.7
Hamada, H.8
Fujii, H.9
Kawamura, K.10
-
75
-
-
0029155706
-
Inducible gene targeting in mice
-
Kuhn R, Schwenk F, Aguet M, Rajewsky K: Inducible gene targeting in mice. Science 1995, 269:1427-1429.
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kuhn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
76
-
-
0029319565
-
Identification of mammalian cell clones exhibiting highly regulated expression from inducible promoters
-
Kirchhoff S, Koster M, Wirth M, Schaper F, Gossen M, Bujard H, Hauser H: Identification of mammalian cell clones exhibiting highly regulated expression from inducible promoters. Trends Gene 1995, 11:219-220.
-
(1995)
Trends Gene
, vol.11
, pp. 219-220
-
-
Kirchhoff, S.1
Koster, M.2
Wirth, M.3
Schaper, F.4
Gossen, M.5
Bujard, H.6
Hauser, H.7
-
77
-
-
0026780670
-
Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations
-
Morgan BA, Izpisua-Belmonte JC, Duboule D, Tabin CJ: Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations. Nature 1992, 358:236-239.
-
(1992)
Nature
, vol.358
, pp. 236-239
-
-
Morgan, B.A.1
Izpisua-Belmonte, J.C.2
Duboule, D.3
Tabin, C.J.4
-
78
-
-
3643071581
-
A method for generating transgenic frog embryos
-
Edited by Sharpe P, Mason I. Totowa, New Jersey: Humana Press, Inc.; in press
-
Amaya E, Kroll KL: A method for generating transgenic frog embryos. In Methods in Molecular Biology: Molecular Embryology, Methods and Prótocols. Edited by Sharpe P, Mason I. Totowa, New Jersey: Humana Press, Inc.; 1996:in press.
-
(1996)
Methods in Molecular Biology: Molecular Embryology, Methods and Prótocols
-
-
Amaya, E.1
Kroll, K.L.2
-
79
-
-
0028034142
-
Of flies and fishes
-
Nusslein-Volhard C: Of flies and fishes. Science 1994, 266:572-574.
-
(1994)
Science
, vol.266
, pp. 572-574
-
-
Nusslein-Volhard, C.1
|