메뉴 건너뛰기




Volumn 39, Issue 7, 1999, Pages 664-669

Intraindividual Variability in Male Hepatic CYP3A4 Activity Assessed by Alfentanil and Midazolam Clearance

Author keywords

[No Author keywords available]

Indexed keywords

ALFENTANIL; CYP3A PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450; INTRAVENOUS ANESTHETIC AGENT; MIDAZOLAM; MIXED FUNCTION OXIDASE;

EID: 0033160860     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/00912709922008290     Document Type: Article
Times cited : (43)

References (36)
  • 2
    • 0030834058 scopus 로고    scopus 로고
    • Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers and inhibitors
    • Rendic S, Di Carlo FJ: Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers and inhibitors. Drug Metab Rev 1997;29:413-580.
    • (1997) Drug Metab Rev , vol.29 , pp. 413-580
    • Rendic, S.1    Di Carlo, F.J.2
  • 3
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP: Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994;270:414-423.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 5
    • 0029584276 scopus 로고
    • Substrates of human hepatic cytochrome P450 3A4
    • Li AP, Kaminski DL, Rasmussen A: Substrates of human hepatic cytochrome P450 3A4. Toxicology 1995;104:1-8.
    • (1995) Toxicology , vol.104 , pp. 1-8
    • Li, A.P.1    Kaminski, D.L.2    Rasmussen, A.3
  • 6
    • 0029128720 scopus 로고
    • Gender effects in pharmacokinetics and pharmacodynamics
    • Harris RZ, Benet LZ, Schwartz JB: Gender effects in pharmacokinetics and pharmacodynamics. Drugs 1995;50:222-239.
    • (1995) Drugs , vol.50 , pp. 222-239
    • Harris, R.Z.1    Benet, L.Z.2    Schwartz, J.B.3
  • 7
    • 0028071759 scopus 로고
    • Noninvasive tests of CYP3A enzymes
    • Watkins PB: Noninvasive tests of CYP3A enzymes. Pharmacogenetics 1994;4:366-368.
    • (1994) Pharmacogenetics , vol.4 , pp. 366-368
    • Watkins, P.B.1
  • 8
    • 0029917318 scopus 로고    scopus 로고
    • Quantification of dextromethorphan and metabolites: A dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity
    • Jones DR, Gorski JC, Hamman MA, Hall SD: Quantification of dextromethorphan and metabolites: a dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity. J Chromatogr B 1996;678:105-111.
    • (1996) J Chromatogr B , vol.678 , pp. 105-111
    • Jones, D.R.1    Gorski, J.C.2    Hamman, M.A.3    Hall, S.D.4
  • 9
    • 0030868233 scopus 로고    scopus 로고
    • The role of cytochrome P450 3A4 in alfentanil clearance: Implications for interindividual variability in disposition and perioperative drug interactions
    • Kharasch ED, Russell M, Mautz D, Thummel KE, Kunze KL, Bowdle TA, et al: The role of cytochrome P450 3A4 in alfentanil clearance: implications for interindividual variability in disposition and perioperative drug interactions. Anesthesiology 1997;87:36-50.
    • (1997) Anesthesiology , vol.87 , pp. 36-50
    • Kharasch, E.D.1    Russell, M.2    Mautz, D.3    Thummel, K.E.4    Kunze, K.L.5    Bowdle, T.A.6
  • 10
    • 0027180023 scopus 로고
    • Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta
    • Schuetz JD, Kauma S, Guzelian PS: Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta. J Clin Invest 1993;92:1018-1024.
    • (1993) J Clin Invest , vol.92 , pp. 1018-1024
    • Schuetz, J.D.1    Kauma, S.2    Guzelian, P.S.3
  • 11
    • 0031891641 scopus 로고    scopus 로고
    • Physiological changes during the menstrual cycle and their effects on the pharmacokinetics and pharmacodynamics of drugs
    • Kashuba AD, Nafziger AN: Physiological changes during the menstrual cycle and their effects on the pharmacokinetics and pharmacodynamics of drugs. Clin Pharmacokinet 1998;34:203-218.
    • (1998) Clin Pharmacokinet , vol.34 , pp. 203-218
    • Kashuba, A.D.1    Nafziger, A.N.2
  • 12
    • 0028114619 scopus 로고
    • Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients
    • Thummel KE, Shen DD, Podoll T, Kunze KL, Trager WF, Hartwell P, et al: Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients. J Pharmacol Exp Ther 1994;271:549-556.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 549-556
    • Thummel, K.E.1    Shen, D.D.2    Podoll, T.3    Kunze, K.L.4    Trager, W.F.5    Hartwell, P.6
  • 13
    • 0027985506 scopus 로고
    • Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intra-individual hepatic CYP3A variability following liver transplantation
    • Thummel KE, Shen DD, Podoll T, Kunze KL, Trager WF, Bacchi CE, et al: Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intra-individual hepatic CYP3A variability following liver transplantation. J Pharmacol Exp Ther 1994;271:557-566.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 557-566
    • Thummel, K.E.1    Shen, D.D.2    Podoll, T.3    Kunze, K.L.4    Trager, W.F.5    Bacchi, C.E.6
  • 14
    • 0030759151 scopus 로고    scopus 로고
    • Assessment of cytochrome P450 3A4 activity during the menstrual cycle using alfentanil as a noninvasive probe
    • Kharasch ED, Russell M, Garton K, Lentz G, Bowdle TA, Cox K: Assessment of cytochrome P450 3A4 activity during the menstrual cycle using alfentanil as a noninvasive probe. Anesthesiology 1997;87:26-35.
    • (1997) Anesthesiology , vol.87 , pp. 26-35
    • Kharasch, E.D.1    Russell, M.2    Garton, K.3    Lentz, G.4    Bowdle, T.A.5    Cox, K.6
  • 16
    • 0028357256 scopus 로고
    • Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole
    • Olkkola KT, Backman JT, Neuvonen PJ: Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994;55:481-485.
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 481-485
    • Olkkola, K.T.1    Backman, J.T.2    Neuvonen, P.J.3
  • 17
    • 0026808682 scopus 로고
    • Identification of the pharmacogenetic determinants of alfentanil metabolism: Cytochrome P450 3A4
    • Yun C-H, Wood M, Wood AJJ, Guengerich FP: Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P450 3A4. Anesthesiology 1992;77:467-474.
    • (1992) Anesthesiology , vol.77 , pp. 467-474
    • Yun, C.-H.1    Wood, M.2    Wood, A.J.J.3    Guengerich, F.P.4
  • 20
    • 0020261684 scopus 로고
    • Physiologic and temporal variation in hepatic elimination of midazolam
    • Klotz U, Ziegler G: Physiologic and temporal variation in hepatic elimination of midazolam. Clin Pharmacol Ther 1982;32:107-112.
    • (1982) Clin Pharmacol Ther , vol.32 , pp. 107-112
    • Klotz, U.1    Ziegler, G.2
  • 21
    • 0022522046 scopus 로고
    • The influence of hepatic plasma flow on alfentanil plasma concentration plateaus achieved with an infusion model in humans: Measurement of alfentanil hepatic extraction coefficient
    • Chauvin M, Bonnet F, Montembault C, Levron JC, Viars P: The influence of hepatic plasma flow on alfentanil plasma concentration plateaus achieved with an infusion model in humans: measurement of alfentanil hepatic extraction coefficient. Anesth Analg 1986;65:999-1003.
    • (1986) Anesth Analg , vol.65 , pp. 999-1003
    • Chauvin, M.1    Bonnet, F.2    Montembault, C.3    Levron, J.C.4    Viars, P.5
  • 26
    • 0031706585 scopus 로고    scopus 로고
    • Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam
    • Kashuba ADM, Bertino JS Jr, Rocci ML Jr, Kulawy RW, Beck DJ, Nafziger AN: Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam. Clin Pharmacol Ther 1998;64:269-277.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 269-277
    • Kashuba, A.D.M.1    Bertino J.S., Jr.2    Rocci M.L., Jr.3    Kulawy, R.W.4    Beck, D.J.5    Nafziger, A.N.6
  • 27
    • 0023280963 scopus 로고
    • Population pharmacokinetics of alfentanil: The average dose-plasma concentration relationship and interindividual variability in patients
    • Maitre PO, Vozeh S, Heykants J, Thomson DA, Stanski DR: Population pharmacokinetics of alfentanil: the average dose-plasma concentration relationship and interindividual variability in patients. Anesthesiology 1987;66:13-16.
    • (1987) Anesthesiology , vol.66 , pp. 13-16
    • Maitre, P.O.1    Vozeh, S.2    Heykants, J.3    Thomson, D.A.4    Stanski, D.R.5
  • 30
    • 0024247094 scopus 로고
    • Effects of age, gender, and oral contraceptives in intramuscular midazolam pharmacokinetics
    • Holazao AA, Winkler MB, Patel IH: Effects of age, gender, and oral contraceptives in intramuscular midazolam pharmacokinetics. J Clin Pharmacol 1988;28:1040-1045.
    • (1988) J Clin Pharmacol , vol.28 , pp. 1040-1045
    • Holazao, A.A.1    Winkler, M.B.2    Patel, I.H.3
  • 32
    • 0023811841 scopus 로고
    • No evidence of a genetic polymorphism in the oxidative metabolism of midazolam
    • Kassai A, Toth G, Eichelbaum M, Klotz U: No evidence of a genetic polymorphism in the oxidative metabolism of midazolam. Clin Pharmacokin 1988;15:319-325.
    • (1988) Clin Pharmacokin , vol.15 , pp. 319-325
    • Kassai, A.1    Toth, G.2    Eichelbaum, M.3    Klotz, U.4
  • 33
    • 0031863228 scopus 로고    scopus 로고
    • Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2, and xanthine oxidase activity determined with caffeine phenotyping
    • Kashuba AD, Bertino JS Jr, Kearns GL, Leeder JS, James AW, Gotschall R, et al: Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2, and xanthine oxidase activity determined with caffeine phenotyping. Clin Pharmacol Ther 1998;63:540-551.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 540-551
    • Kashuba, A.D.1    Bertino J.S., Jr.2    Kearns, G.L.3    Leeder, J.S.4    James, A.W.5    Gotschall, R.6
  • 34
    • 0030015297 scopus 로고    scopus 로고
    • Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism
    • Thummel KE, O'Shea D, Paine MF, Shen DD, Kunze KL, Perkins JD, et al: Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism. Clin Pharmacol Ther 1996;59:491-502.
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 491-502
    • Thummel, K.E.1    O'Shea, D.2    Paine, M.F.3    Shen, D.D.4    Kunze, K.L.5    Perkins, J.D.6
  • 35
  • 36
    • 0028820208 scopus 로고
    • Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
    • Wu C-Y, Benet LZ, Hebert MF, Gupta SK, Rowland M, Gomez DY, et al: Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine. Clin Pharmacol Ther 1995;58:492-497.
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 492-497
    • Wu, C.-Y.1    Benet, L.Z.2    Hebert, M.F.3    Gupta, S.K.4    Rowland, M.5    Gomez, D.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.