6-Mercaptopurine dose escalation and its effect on drug tolerance in childhood lymphoblastic leukaemia

Cancer Chemotherapy and Pharmacology

Volumn 38, Issue 1, 1996, Pages 113-116

  Welch, Jennifer C ^a   Lilleyman, John S ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

6 Mercaptopurine; Lymphoblastic leukaemia; Myelosuppression

Indexed keywords

MERCAPTOPURINE; METHOTREXATE;

ARTICLE; BONE MARROW SUPPRESSION; CHILDHOOD CANCER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG TOLERANCE; FEMALE; HUMAN; LYMPHATIC LEUKEMIA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NEUTROPENIA; ORAL DRUG ADMINISTRATION; PRESCRIPTION; PRIORITY JOURNAL; THROMBOCYTOPENIA;

6-MERCAPTOPURINE; ANTIMETABOLITES, ANTINEOPLASTIC; BONE MARROW; CHILD, PRESCHOOL; COHORT STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; FEMALE; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC; MALE; NEUTROPENIA; THROMBOCYTOPENIA;

EID: 0029931874     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050457     Document Type: Article

References (9)

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9. Working party on Leukaemia in childhood. (1986) Report to the Council by the Working Party on Leukaemia in Childhood. Medical Research Council Leukaemia Trial UKALL V: an attempt to reduce the immunosuppressive effects of therapy in childhood acute lymphoblastic leukaemia. J Clin Oncol 4:1758