Construction and in vitro functional evaluation of a low-density lipoprotein receptor/transferrin fusion protein as a therapeutic tool for familial hypercholesterolemia

Human Gene Therapy

Volumn 10, Issue 7, 1999, Pages 1219-1228

  Parise, Flavia ^a   Simone, Luisa ^a   Croce, Maria Antonietta ^a   Ghisellini, Margherita ^a   Battini, Renata ^a   Borghi, Serena ^a   Tiozzo, Roberta ^a   Ferrari, Sergio ^a   Calandra, Sebastiano ^a   Ferrari, Stefano ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; HYBRID PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; TRANSFERRIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA SEQUENCE; EXPRESSION VECTOR; FAMILIAL HYPERCHOLESTEROLEMIA; FIBROBLAST; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; INTERNALIZATION; NONHUMAN; PROTEIN BINDING; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

ANIMALS; COS CELLS; DNA, COMPLEMENTARY; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; LIPOPROTEINS, LDL; PLASMIDS; PRECIPITIN TESTS; RABBITS; RECEPTORS, LDL; RECOMBINANT FUSION PROTEINS; TRANSFECTION; TRANSFERRIN;

EID: 0033135629     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950018201     Document Type: Article

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