No association of HIV type 1 long terminal repeat sequence pattern with long-term nonprogression and in vivo viral replication levels in European subjects

AIDS Research and Human Retroviruses

Volumn 15, Issue 7, 1999, Pages 609-617

  Visco Comandini, Ubaldo ^a,b   Yun, Zhibing ^a   Vahlne, Anders ^a   Sönnerborg, Anders ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL FEATURE; GENE MUTATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONG TERMINAL REPEAT; NONHUMAN; PATHOGENESIS; PHYLOGENY; PRIORITY JOURNAL; PROVIRUS; VIRUS LOAD; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

EID: 0033135516     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922299310908     Document Type: Article

References (39)

1. Buchbinder SP, Katz MH, Hessol NA, O'Malley PM, and Holmberg SD: Long-term HIV-1 infection without immunologic progression. AIDS 1994;8:1123-1128.
2. Straathdee S, Veugelers P, Page-Shafer K, McNulty A, Moss A, Schechter M, van Griensven G, and Coutinho R: Lack of consistency between five definitions of nonprogression in cohorts of HIV-infected seroconverters. AIDS 1996;10:959-965.
3. Balotta C, Bagnarelli P, Riva C, Valenza A, Antinori S, Colombo MC, Sampaolesi R, Violin M, Depasquale MP, Moroni M, Clementi M, and Galli M: Comparable biological and molecular determinants in HIV type 1-infected long-term nonprogressors and recently infected individuals. AIDS Res Hum Retroviruses 1997; 13:337-341.
4. Simmonds P, Balfe P, Peutherer JF, Ludlam CA, Bishop JO, and Brown AJ: Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers. J Virol 1990;64:864-872.
5. Pantaleo G, Menzo S, Vaccarezza M, Graziosi C, Cohen OJ, Demarest JF, Montefiori D, Orenstein JM, Fox C, Schrager LK, Margolick JB, Buchbinder S, Giorgi JV, and Fauci AS: Studies in subjects with long-term nonprogressive human immunodeficiency virus infection. N Engl J Med 1995;332:209-216.
6. Cao Y, Qin L, Zhang L, Safrit J, and Ho DD: Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N Engl J Med 1995;332: 201-209.
7. Broström C, Visco Comandini U, Yun Z, and Sönnerborg A: Longitudinal quantification of HIV-1 DNA and plasma HIV-1 RNA in long-term nonprogressors. J Infect Dis 1999; in press.
8. Rump J, Peter H, Schneider J, Haller O, and Meyerhans A: Long-term survivors with continuously high levels of HIV type 1. AIDS Res Hum Retroviruses 1996;12:757-758.
9. Zimmerman PA, Bucklerwhite A, Alkhatib G, Spalding T, Kubofcik J, Combadiere C, Weissman D, Cohen O, Rubbert A, Lam G, Vaccarezza M, Kennedy PE, Kumaraswami V, Giorgi JV, Detels R, Hunter J, Chopek M, Berger EA, Fauci AS, Nutman TB, and Murphy PM: Inherited resistance to HIV-1 conferred by an inactivating mutation in cc chemokine receptor 5 - studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk. Mol Med 1997;3:23-36.
10. Visco Comandini U, Hultgren C, Broström C, Birk M., Kim S, and Sällberg M: Human immunodeficiency virus type-1 disease progression, CC-chemokine receptor 5 genotype and specific immune responses. Clin Diagn Lab Immunol 1998;5:463-466.
11. Haynes BF, Pantaleo G, and Fauci AS: Toward an understanding of the correlates of protective immunity to HIV infection. Science 1996;271:324-328.
12. Schwartz D, Sharma U, Busch M, Weinhold K, Matthews T, Lieberman J, Birx D, Farzedagen H, Margolick J, Quinn T, Davis B, Bagasra O, Pomerantz R, and Viscidi R: Absence of recoverable infectious virus and unique immune responses in an asymptomatic HIV+ long-term survivor. AIDS Res Hum Retroviruses 1994;10:1703-1711.
13. Montefiori DC, Pantaleo G, Fink LM, Zhou JT, Zhou JY, Bilska M, Miralles GD, and Fauci AS: Neutralizing and infection-enhancing antibody responses to human immunodeficiency virus type 1 in long-term nonprogressors. J Infect Dis 1996;173:60-67.
14. Schwartz DH, Viscidi R, Laeyendecker O, Song H, Ray SC, and Michael N: Predominance of defective proviral sequences in an HIV+ long-term non-progressor. Immunol Lett 1996;51:3-6.
15. Wang B, Ge Y, Palasanthiran P, Xiang S, Ziegler J, Dweyer D, Randle C, Dowton D, Cunningham A, and Saksena N: Gene defects clustered at the C-terminus of the vpr gene of HIV-1 in long-term nonprogressing mother and child pair: In vivo evolution of vpr quasispecies in blood and plasma. Virology 1996;223:224-232.
16. Iversen AK, Shpaer EG, Rodrigo AG, Hirsch MS, Walker BD, Sheppard HW, Merigan TC, and Mullins JI: Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual. J Virol 1995;69:5743-5753.
17. Michael NL, Chang G, d'Arcy LA, Ehrenberg PK, Mariani R, Busch MP, Birx DL, and Schwartz DH: Defective accessory genes in a human immunodeficiency virus type 1-infected long-term survivor lacking recoverable virus. J Virol 1995;69:4228-4236.
18. Huang H, Zhang L, and Ho D: Characterization of gag and pol sequences from long-term survivors of human immunodeficiency virus type 1 infection. Virology 1998;240:36-49.
19. Kestler HWD, Ringler DJ, Mori K, Panicali DL, Sehgal PK, Daniel MD, and Desrosiers RC: Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 1991;65:651-662.
20. Deacon NJ, Tsykin A, Solomon A, Smith K, Ludford-Menting M, Hooker DJ, McPhee DA, Greenway AL, Ellett A, Chatfield C, Lawson VA, Crowe S, Maerz A, Sonza S, Learmont J, Sullivan JS, Cunningham A, Dwyer D, Dowton D, and Mills J: Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 1995;270:988-991.
21. Kirchhoff F, Greenough TC, Brettler DB, Sullivan JL, and Desrosiers RC: Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N Engl J Med 1995;332:228-232.
22. Huang Y, Zhang L, and Ho DD: Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection. J Virol 1995;69:93-100.
23. Visco Comandini U, Yun Z, Paganelli R, Orlandi P, Salotti A, Johansson B, Vahlne A, and Sönnerborg A: HIV-1 nef mutations and clinical long-term non progression: A molecular epidemiology study. J Hum Virol 1998;1:320-327.
24. Mariani R, Kirchhoff F, Greenough TC, Sullivan JL, Desrosiers RC, and Skowronski J: High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection. J Virol 1996;70:7752-7764.
25. Salvi R, Garbuglia AR, Di Caro A, Pulciani S, Montella F, and Benedetto A: Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor. J Virol 1998;72:3646-3657.
26. Zhang L, Huang Y, Yuan H, Chen B, Ip J, and Ho D: Genotypic and phenotypic characterization of long terminal repeat sequences from long-term survivors of human immunodeficiency virus type 1 infection. J Virol 1997;71:5608-5613.
27. Rousseau C, Abrams E, Lee M, Urbano R, and King M: Long terminal repeat and nef gene variants of human immunodeficiency virus type 1 in perinatally infected long-term survivors and rapid progressors. AIDS Res Hum Retroviruses 1997;13:1611-1623.
28. Ganor R: Cellular transcription factors involved in the regulation of HIV-1 gene expression. AIDS 1992;6:347-363.
29. Mallardo M, Dragonetti E, Baldassarre F, Ambrosino C, Scala G, and Quinto I: An NF-kappaB site in the 5′-untranslated leader region of the human immunodeficiency virus type 1 enhances the viral expression in response to NF-kappaB-activating stimuli. J Biol Chem 1996;271:20820-20827.
30. Cullen BR: Regulation of HIV gene expression. AIDS 1995; 9(Suppl. A):S19-S32.
31. Sherefa K, Sönnerborg A, Steinbergs J, and Sallberg M: Rapid grouping of HIV-1 infection in subtypes A to E by V3 peptide serotyping and its relation to sequence analysis. Biochem Biophys Res Commun 1994;205:1658-1664.
32. Visco Comandini U, Sönnerborg A, Vahlne A, and Yun Z: Quantification of HIV-1 proviral DNA from peripheral blood mononuclear cells using a high throughput four-competitor competitive PCR. J Virol Methods 1997;69:171-180.
33. Salminen MO, Koch C, Sanders-Buell E, Ehrenberg PK, Michael NL, Carr JK, Burke DS, and McCutchan FE: Recovery of virtually full-length HIV-1 provirus of diverse subtypes from primary virus cultures using the polymerase chain reaction. Virology 1995;213:80-86.
34. Meyers G, Hahn B, Mellors J, Henderson L, Korber B, Jeang K-T, McCutchan F, and Pavlakis G: Human Retroviruses and AIDS. Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, 1995.
35. Felsenstein J: Phylogenies from molecular sequences: Inference and reliability. Annu Rev Genet 1988;22:521-565.
36. Khoury M, Beaty T, and Cohen B: Sources of bias in epidemiologic studies. In: Fundamentals of Genetic Epidemiology. Oxford University PRess, New York, 1993, pp. 79-81.
37. Estable M, Bell B, Merzouki A, Montaner J, O'Shaughnessy M, and Sadowski IJ: Human immunodeficiency virus type 1 long terminal repeat variants from 42 patients representing all stages of infection display a wide range of sequence polymorphism and transcription activity. J Virol 1996;70:4053-4062.
38. Golub E, Li G, and Volsky D: Differences in the basal activating of the long terminal repeat determine different replicative capacities of two closely related human immunodeficiency virus type 1 isolates. J Virol 1990;64:3654-3660.
39. Gao F, Robertson D, Morrison SG, Hui H, Craig S, Decker J, Fultz PN, Girard M, Shaw GM, Hahn BH, and Sharp PM: The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (A/E) recombinant of African origin. J Virol 1996;70:7013-7029.