Percutaneous adenoviral gene transfer into porcine coronary arteries: Is catheter-based gene delivery adapted to coronary circulation?

Human Gene Therapy

Volumn 10, Issue 7, 1999, Pages 1105-1115

  Varenne, Olivier ^a,b   Gerard, Robert D ^a   Sinnaeve, Peter ^b   Gillijns, Hilde ^a   Collen, Desire ^a   Janssens, Stefan ^a,b,c  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c Cardiac Unit   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATHETER; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; ENZYME ACTIVITY; GENE TARGETING; GENE TRANSFER; HALF LIFE TIME; HEART; LIVER; NONHUMAN; SWINE;

ADENOVIRIDAE; ADMINISTRATION, CUTANEOUS; ANGIOPLASTY, BALLOON; ANIMALS; CATHETERIZATION; CORONARY DISEASE; CORONARY VESSELS; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; LUCIFERASES; MUSCLE, SMOOTH; SWINE;

EID: 0033135213     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950018102     Document Type: Article

References (34)

1. BAEK, S., and MARCH, K.L. (1998). Gene therapy for restenosis. Getting nearer the heart of the matter. Circ. Res. 82, 295-305.
2. BARATH, P., POPOV, A., DILLEHAY, G.L., MATOS, G., and MCKIERNAN, T. (1997). Infiltrator angioplasty balloon catheter: A device for combined angioplasty and intramural site-specific treatment. Cathet. Cardiovasc. Diagn. 41(3), 333-341.
3. CHANG, M.W., BARR, E., LU, M.M., BARTON, K., and LEIDEN, J.M. (1995a). Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J. Clin. Invest. 96(5), 2260-2268.
4. CHANG, M.W., BARR, E., SELTZER, J., JIANG, Y.Q., NABEL, G.J., NABEL, E.G., PARMACEK, M.S., and LEIDEN, J.M. (1995b). Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product. Science 267(5197), 518-522.
5. CHANG, M.W., OHNO, T., GORDON, D., LU, M.M., NABEL, G.J., NABEL, E.G., and LEIDEN, J.M. (1995c). Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery. Mol. Med. 1(2), 172-181.
6. CHAPMAN, G.D., LIM, C.S., GAMMON, R.S., CULP, S.C., DESPER, J.S., BAUMAN, R.P., SWAIN, J.L., and STACK, R.S. (1992). Gene transfer into coronary arteries of intact animals with a percutaneous balloon catheter. Circ. Res. 71(1), 27-33.
7. DEYOUNG, M., and DICHEK, D.A. (1998). Gene therapy for restenosis. Are we ready? Circ. Res. 82, 306-313.
8. FALLAUX, F.J., KRANENBURG, O., CRAMER, S.J., HOUWELING, A., VAN ORMONDT, H., HOEBEN, R.C., and VAN DER EB, A.J. (1996). Characterization of 911: A new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors. Hum. Gene Ther. 7(2), 215-222.
9. FRENCH, B.A., MAZUR, W., ALI, N.M., GESKE, R.S., FINNIGAN, J.P., RODGERS, G.P., ROBERTS, R., and RAIZNER, A.E. (1994). Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis. Circulation 90(5), 2402-2413.
10. GERARD, R.D., and MEIDELL, R.S. (1995). Adenovirus vectors. In DNA Cloning: A Practical Approach: Mammalian Systems. B.D. Hames and D. Glover, eds. (Oxford University Press, Oxford) pp. 285-307.
11. GUZMAN, R.J., HIRSCHOWITZ, E.A., BRODY, S.L., CRYSTAL, R.G., EPSTEIN, S.E., and FINKEL, T. (1994). In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene. Proc. Natl. Acad. Sci. U.S.A. 91(22), 10732-10736.
12. HERZ, J., and GERARD, R.D. (1993). Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc. Natl. Acad. Sci. U.S.A. 90(7), 2812-2816.
13. JANSSENS, S., FLAHERTY, D., NONG, Z., VARENNE, O., VAN PELT, N., HAUSTERMANS, C., ZOLDHELYI, P., GERARD, R., and COLLEN, D. (1998). Human endothelial nitric oxide synthase gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation after balloon injury in rats. Circulation 97, 1274-1281.
14. LANDAU, C., PIRWITZ, M.J., WILLARD, M.A., GERARD, R.D., MEIDELL, R.S., and WILLARD, S.E. (1995). Adenoviral mediated gene transfer to atherosclerotic arteries after balloon angioplasty. Am. Heart J. 129(6), 1051-1057.
15. LEE, S.W., TRAPNELL, B.C., RADE, J.J., VIRMANI, R., and DICHEK, D.A. (1993). In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries. Circ. Res. 73(5), 797-807.
16. LINCOFF, A.M., TOPOL, E.J., and ELLIS, S.G. (1994). Local drug delivery for the prevention of restenosis. Fact, fancy, and future. Circulation 90(4), 2070-2084.
17. MANN, M.J., WHITTEMORE, A.D., DONALDSON, M.C., BELKIN, M.A., CONTE, M.S., ORAV, J., POLAK, J.F., and DZAU, V.J. (1998). The PREVENT trial of vein graft genetic engineering: Preliminary molecular and clinical findings. Circulation 98(17), 1683A.
18. NABEL, E.G., PLAUTZ, G., and NABEL, G.J. (1990). Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science 249(4974), 1285-1288.
19. NABEL, E.G., SHUM, L., POMPILI, V.J., YANG, Z.Y., SAN, H., SHU, H.B., LIPTAY, S., GOLD, L., GORDON, D., DERYNCK, R., and NABEL, G.J. (1993a). Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia. Proc. Natl. Acad. Sci. U.S.A. 90(22), 10759-10763.
20. NABEL, E.G., YANG, Z., LIPTAY, S., SAN, H., GORDON, D., HAUDENSCHILD, C.C., and NABEL. G.J. (1993b). Recombinant platelet-derived growth factor B gene expression in porcine arteries induces intimal hyperplasia in vivo. J. Clin. Invest. 91(4), 1822-1829.
21. PAVLIDES, G.S., BARATH, P., MAGINAS, A., VASILIKOS, V., COKKINOS, D.V., and O'NEILL, W.W. (1997). Intramural drug delivery by direct injection within the arterial wall: First clinical experience with a novel intracoronary delivery-infiltrator system. Cathet. Cardiovasc. Diagn. 41(3), 287-292.
22. PERLMAN, H., MAILLARD, L., KRASINSKI, K., and WALSH, K. (1997). Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury. Circulation 95(4), 981-987.
23. RADE, J.J., SCHULICK, A.H., VIRMANI, R., and DICHEK, D.A. (1996). Local adenoviral-mediated expression of recombinant hirudin reduces neointima formation after arterial injury. Nature Med. 2(3), 293-298.
24. RIVARD, A., PERLMAN, H., LUO, Z., FABRE, J.-E., and WALSH, K. (1998). Parameters influencing local gene delivery following angioplasty in rabbit single and double injury models. J. Am. Coll. Cardiol. 31(2, Suppl. A), 102A.
25. ROME, J.J., SHAYANI, V., FLUGELMAN, M.Y., NEWMAN, K.D., FARB, A., VIRMANI, R., and DICHEK, D.A. (1994). Anatomic barriers influence the distribution of in vivo gene transfer into the arterial wall. Modeling with microscopic tracer particles and verification with a recombinant adenoviral vector. Arterioscler. Thromb. 14(1), 148-161.
26. SIMARI, R.D., SAN, H., REKHTER, M., OHNO, T., GORDON, D., NABEL, G.J., and NABEL, E.G. (1996). Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries. J. Clin. Invest. 98(1), 225-235.
27. STEG, P.G., TAHLIL, O., AUBAILLY, N., CAILLAUD, J.M., DEDIEU, J.F., BERTHELOT, K., LE ROUX, A., FELDMAN, L., PERRICAUDET, M., DENEFLE, P., and BRANELLEC, D. (1997). Reduction of restenosis after angioplasty in an atheromatous rabbit model by suicide gene therapy. Circulation 96(2), 408-411.
28. TAHLIL, O., BRAMI, M., FELDMAN, L.J., BRANELLEC, D., and STEG, P.G. (1997). The Dispatch catheter as a delivery tool for arterial gene transfer. Cardiovasc Res 33(1), 181-187.
29. TIO, R.A., SCHEUERMANN, T.H., LEBHERZ, C., LUO, Z., AUBAILLY, N., DUVERGER, N., BRANELLEC, D., and WALSH, K. (1998). Adenovirus-mediated GAX gene transfer reduces in-stent restenosis in pig coronary arteries. Circulation 98(17), 3548A.
30. VAN DER EB, M.M., CRAMER, S.J., VERGOUWE, Y., SCHAGEN, F.H., VAN KRIEKEN, J.H., VAN DER EB, A.J., RINKES, I.H., VAN DE VELDE, C.J., and HOEBEN, R.C. (1998). Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration. Gene Ther. 5(4), 451-458.
31. VARENNE, O., PISLARU, S., GILLIJNS, H., VAN PELT, N., GERARD, R.D., ZOLDHELYI, P., VAN DE WERF, F., COLLEN, D., and JANSSENS, S.P. (1998). Local adenoviral-mediated transfer of human endothelial nitric oxide synthase reduces luminal narrowing following coronary angioplasty in pigs. Circulation 98, 919-926.
32. VARLEY, A.W., COULTHARD, M.G., MEIDELL, R.S., GERARD, R.D., and MUNFORD, R.S. (1995). Inflammation-induced recombinant protein expression in vivo using promoters from acute-phase protein genes. Proc. Natl. Acad. Sci. U.S.A. 92(12), 5346-5350.
33. WILENSKY, R.L., TANGUAY, J.F., ITO, S., BARTORELLI, A.L., MOSES, J., WILLIAMS, D.O., BUCHER, T.A., GALLANT, P., WU, H., POPMA, J.J., WEISMANN, N., MINTZ, G.S., KAPLAN, A.V., and LEON, M.B. (1998). The Heparin Infusion Prior to Stenting (HIPS) trial: Procedural, in-hospital, 30 day, and six month clinical, angiographic and IVUS results. J. Am. Coll. Cardiol. 31(2, Suppl. A), 457A.
34. WILLARD, J.E., LANDAU, C., GLAMANN, D.B., BURNS, D., JESSEN, M.E., PIRWITZ, M.J., GERARD, R.D., and MEIDELL, R.S. (1994). Genetic modification of the vessel wall. Comparison of surgical and catheter-based techniques for delivery of recombinant adenovirus. Circulation 89(5), 2190-2197.