메뉴 건너뛰기




Volumn 14, Issue 5, 1999, Pages 897-904

Reduced substratum adhesion and decreased expressions of β1 and β4 integrins in human breast cancer cells with a property of anchorage-independent growth

Author keywords

Anchorage independent growth; Cell adhesion; Human breast cancer; Integrins 1 and 4

Indexed keywords

ANTIBODY; BETA1 INTEGRIN; BETA4 INTEGRIN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN;

EID: 0033127162     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (47)
  • 1
    • 0014418101 scopus 로고
    • Anchorage and growth regulation in normal and virus-transformed cells
    • Stoker M, O'Neill C, Berryman S and Waxman V: Anchorage and growth regulation in normal and virus-transformed cells. Int J Cancer 3: 683-693, 1968.
    • (1968) Int J Cancer , vol.3 , pp. 683-693
    • Stoker, M.1    O'Neill, C.2    Berryman, S.3    Waxman, V.4
  • 2
    • 0018140371 scopus 로고
    • Role of cell shape in growth control
    • Folkman J and Moscona A: Role of cell shape in growth control. Nature 273: 345-349, 1978.
    • (1978) Nature , vol.273 , pp. 345-349
    • Folkman, J.1    Moscona, A.2
  • 3
    • 0027445508 scopus 로고
    • Proteins associated with the cytoplasmic surface of adhesion molecules
    • Gumbiner BM: Proteins associated with the cytoplasmic surface of adhesion molecules. Neuron 11: 551-564, 1993.
    • (1993) Neuron , vol.11 , pp. 551-564
    • Gumbiner, B.M.1
  • 4
    • 0028351295 scopus 로고
    • Role of adhesion molecule cytoplasmic domains in mediating interactions with the cytoskeleton
    • Pavalko FM and Otey CA: Role of adhesion molecule cytoplasmic domains in mediating interactions with the cytoskeleton. Proc Soc Exp Biol Med 205: 282-293, 1994.
    • (1994) Proc Soc Exp Biol Med , vol.205 , pp. 282-293
    • Pavalko, F.M.1    Otey, C.A.2
  • 6
    • 0029164237 scopus 로고
    • Integrin transmembrane signaling and cytoskeletal control
    • Yamada KM and Miyamoto S: Integrin transmembrane signaling and cytoskeletal control. Curr Opin Cell Biol 7: 681-689, 1995.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 681-689
    • Yamada, K.M.1    Miyamoto, S.2
  • 7
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark EA and Brugge JS: Integrins and signal transduction pathways: the road taken. Science 26: 233-239, 1995.
    • (1995) Science , vol.26 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 8
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • Schaller MD and Parsons JT: Focal adhesion kinase and associated proteins. Curr Opin Cell Biol 6: 705-710, 1994.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 705-710
    • Schaller, M.D.1    Parsons, J.T.2
  • 9
    • 0028109766 scopus 로고
    • Regulation of protein tyrosine kinases in platelets
    • Clark EA, Shattil SJ and Brugge JS: Regulation of protein tyrosine kinases in platelets. Trends Biochcm Sci 19: 464-469, 1994.
    • (1994) Trends Biochcm Sci , vol.19 , pp. 464-469
    • Clark, E.A.1    Shattil, S.J.2    Brugge, J.S.3
  • 10
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction link to Ras pathway by GRB2 binding to focal adhesion kinase
    • Schlaepfer DD, Hanks SK, Hunter T and van der Geer P: Integrin-mediated signal transduction link to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372: 786-791, 1994.
    • (1994) Nature , vol.372 , pp. 786-791
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.3    Van Der Geer, P.4
  • 11
    • 0027939187 scopus 로고
    • Integrin-mediated cell adhesion activates mitogen-activated protein kinases
    • Chen Q, Kinch MS, Lin TH, Burridge K and Juliano RL: Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J Biol Chem 269: 26602-26605, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 26602-26605
    • Chen, Q.1    Kinch, M.S.2    Lin, T.H.3    Burridge, K.4    Juliano, R.L.5
  • 12
    • 0031003237 scopus 로고    scopus 로고
    • Cell anchorage permits efficient signal transduction between ras and tis downstream kinases
    • Lin TH, Chen Q, Howe A and Juliano RL: Cell anchorage permits efficient signal transduction between ras and tis downstream kinases. J Biol Chem 272: 8849-8852, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 8849-8852
    • Lin, T.H.1    Chen, Q.2    Howe, A.3    Juliano, R.L.4
  • 13
    • 0030766846 scopus 로고    scopus 로고
    • Activation of the MAP kinase pathway by growth factors requires integrin-mediated cell adhesion
    • Renshaw MW, Ren XD and Schwartz MA: Activation of the MAP kinase pathway by growth factors requires integrin-mediated cell adhesion. EMBO J 16: 5592-5599, 1997.
    • (1997) EMBO J , vol.16 , pp. 5592-5599
    • Renshaw, M.W.1    Ren, X.D.2    Schwartz, M.A.3
  • 14
    • 0027176804 scopus 로고
    • Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown
    • McNamee HM, Ingber DE and Schwartz MA: Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown. J Cell Biol 121: 673-678, 1992.
    • (1992) J Cell Biol , vol.121 , pp. 673-678
    • McNamee, H.M.1    Ingber, D.E.2    Schwartz, M.A.3
  • 16
    • 0028036684 scopus 로고
    • The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
    • Chong LD, Traynor-Kaplan A, Bokoch GM and Schwartz MA: The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79: 507-513, 1994.
    • (1994) Cell , vol.79 , pp. 507-513
    • Chong, L.D.1    Traynor-Kaplan, A.2    Bokoch, G.M.3    Schwartz, M.A.4
  • 17
    • 0029828456 scopus 로고    scopus 로고
    • Involvement of the small GTPase Rho in integrin-mediated activation of MAP kinase
    • Renshaw MW, Toksoz D and Schwartz MA: Involvement of the small GTPase Rho in integrin-mediated activation of MAP kinase. J Biol Chem 271: 21691-21694, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 21691-21694
    • Renshaw, M.W.1    Toksoz, D.2    Schwartz, M.A.3
  • 18
    • 0030913673 scopus 로고    scopus 로고
    • Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
    • Khwaja A, Rodriguez-Viciana P, Wennstrom S, Warne PH and Downward J: Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J 161: 2783-2793, 1997.
    • (1997) EMBO J , vol.161 , pp. 2783-2793
    • Khwaja, A.1    Rodriguez-Viciana, P.2    Wennstrom, S.3    Warne, P.H.4    Downward, J.5
  • 19
    • 0030582716 scopus 로고    scopus 로고
    • Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of cdk2 inhibitors
    • Koyama H, Raines EW, Bornfeldt KE, Roberts JM and Ross R: Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of cdk2 inhibitors. Cell 87: 1069-1078, 1996.
    • (1996) Cell , vol.87 , pp. 1069-1078
    • Koyama, H.1    Raines, E.W.2    Bornfeldt, K.E.3    Roberts, J.M.4    Ross, R.5
  • 20
    • 0029827248 scopus 로고    scopus 로고
    • Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway
    • Schwartz MA, Toksoz D and Khosravi-Far R: Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway. EMBO J 15: 6525-6530, 1996.
    • (1996) EMBO J , vol.15 , pp. 6525-6530
    • Schwartz, M.A.1    Toksoz, D.2    Khosravi-Far, R.3
  • 21
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion dependent cell survival by focal adhesion kinase
    • Frisch SM, Vuori K, Ruoslahti E and Chan PY: Control of adhesion dependent cell survival by focal adhesion kinase. J Cell Biol 134: 793-799, 1996.
    • (1996) J Cell Biol , vol.134 , pp. 793-799
    • Frisch, S.M.1    Vuori, K.2    Ruoslahti, E.3    Chan, P.Y.4
  • 23
    • 0028881598 scopus 로고
    • The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation
    • Renshaw MW, McWhirter JR and Wang JYJ: The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation. Mol Cell Biol 15: 1286-1293, 1995.
    • (1995) Mol Cell Biol , vol.15 , pp. 1286-1293
    • Renshaw, M.W.1    McWhirter, J.R.2    Wang, J.Y.J.3
  • 24
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation and signaling in cell adhesion
    • Hynes RO: Integrins: versatility, modulation and signaling in cell adhesion. Cell 69: 11-25, 1992.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 25
    • 0025248510 scopus 로고
    • The role of integrins α2β1 and α3β1 in cell-cell and cell-substrate adhesion of human epithelia cells
    • Carter WG, Wayner EA, Bouchard TS and Kaur P: The role of integrins α2β1 and α3β1 in cell-cell and cell-substrate adhesion of human epithelia cells. J Cell Biol 110: 1387-1404, 1990.
    • (1990) J Cell Biol , vol.110 , pp. 1387-1404
    • Carter, W.G.1    Wayner, E.A.2    Bouchard, T.S.3    Kaur, P.4
  • 26
    • 0028218489 scopus 로고
    • Integrin expression and localization in normal MDCK cells and transformed MDCK cells lacking apical polarity
    • Schoenenberger C-A, Zuk A, Zinkl GM, Kendall D and Matlin KS: Integrin expression and localization in normal MDCK cells and transformed MDCK cells lacking apical polarity. J Cell Sci 107: 527-541, 1994.
    • (1994) J Cell Sci , vol.107 , pp. 527-541
    • Schoenenberger, C.-A.1    Zuk, A.2    Zinkl, G.M.3    Kendall, D.4    Matlin, K.S.5
  • 27
    • 0027679403 scopus 로고
    • Integrin cytoplasmic domains: Mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
    • Sastry SK and Horwitz AF: Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling. Curr Opin Cell Biol 5: 819-831, 1993.
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 819-831
    • Sastry, S.K.1    Horwitz, A.F.2
  • 28
    • 0025679064 scopus 로고
    • Distinct functions for integrins α3β1 in focal adhesions and α6β4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: Relation to hemidesmosomes
    • Carter WG, Kaur P, Gil SG, Gahr PJ and Wayner WA: Distinct functions for integrins α3β1 in focal adhesions and α6β4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes. J Cell Biol 111: 3141-3154, 1990.
    • (1990) J Cell Biol , vol.111 , pp. 3141-3154
    • Carter, W.G.1    Kaur, P.2    Gil, S.G.3    Gahr, P.J.4    Wayner, W.A.5
  • 29
    • 0025360793 scopus 로고
    • The α6β1 (VLA-6) and α6β4 protein complexes: Tissue distribution and biochemical properties
    • Sonnenberg A, Linders CJT, Daams JH and Kennel SJ: The α6β1 (VLA-6) and α6β4 protein complexes: tissue distribution and biochemical properties. J Cell Sci 96: 207-217, 1990.
    • (1990) J Cell Sci , vol.96 , pp. 207-217
    • Sonnenberg, A.1    Linders, C.J.T.2    Daams, J.H.3    Kennel, S.J.4
  • 30
    • 0025254637 scopus 로고
    • Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes
    • Stepp MA, Elwell J and Gipson IK: Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes. Proc Natl Acad Sci USA 87: 8970-8974, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8970-8974
    • Stepp, M.A.1    Elwell, J.2    Gipson, I.K.3
  • 33
    • 0017202090 scopus 로고
    • The hemidesmosome: New fine structural features revealed by freeze-fracture technique
    • Shienvold FL and Kelly DE: The hemidesmosome: new fine structural features revealed by freeze-fracture technique. Cell Tissue Res 172: 289-307, 1976.
    • (1976) Cell Tissue Res , vol.172 , pp. 289-307
    • Shienvold, F.L.1    Kelly, D.E.2
  • 36
    • 0028944247 scopus 로고
    • A recombinant tail-less integrin α6β4 subunit disrupts hemidesmosomes, but does not suppress α6β4-mediated cell adhesion to laminins
    • Spinardi L, Einheber S, Cullen T, Milner TA and Giancotti FG: A recombinant tail-less integrin α6β4 subunit disrupts hemidesmosomes, but does not suppress α6β4-mediated cell adhesion to laminins. J Cell Biol 129: 473-487, 1995.
    • (1995) J Cell Biol , vol.129 , pp. 473-487
    • Spinardi, L.1    Einheber, S.2    Cullen, T.3    Milner, T.A.4    Giancotti, F.G.5
  • 37
    • 0030046992 scopus 로고    scopus 로고
    • Anchorage mediated by integrin α6β4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein
    • Xia Y, Gil SG and Carter WG: Anchorage mediated by integrin α6β4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein. J Cell Biol 132: 727-740, 1996.
    • (1996) J Cell Biol , vol.132 , pp. 727-740
    • Xia, Y.1    Gil, S.G.2    Carter, W.G.3
  • 38
    • 0024430105 scopus 로고
    • A novel integrin (αEβ4) from human epithelial cells suggests a fourth family of integrin adhesion receptors
    • Kajiji S, Tamura RN and Quaranta V: A novel integrin (αEβ4) from human epithelial cells suggests a fourth family of integrin adhesion receptors. EMBO J 8: 673-680, 1989.
    • (1989) EMBO J , vol.8 , pp. 673-680
    • Kajiji, S.1    Tamura, R.N.2    Quaranta, V.3
  • 39
    • 0027369205 scopus 로고
    • The β4 subunit cytoplasmic domain mediates the interaction of α6β4 integrin with the cytoskeleton of hemidesmosomes
    • Spinardi L, Ren Y-L, Sanders R and Giancotti FG: The β4 subunit cytoplasmic domain mediates the interaction of α6β4 integrin with the cytoskeleton of hemidesmosomes. Mol Biol Cell 4: 871-884, 1993.
    • (1993) Mol Biol Cell , vol.4 , pp. 871-884
    • Spinardi, L.1    Ren, Y.-L.2    Sanders, R.3    Giancotti, F.G.4
  • 40
    • 0029115343 scopus 로고
    • Signal transduction by the α6β4 integrin: Distinct β4 subunit sites mediate recruitement of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes
    • Mainiero F, Pepe A, Wary KK, Spinardi L, Mohammadi M, Schlessinger J and Giancotti FG: Signal transduction by the α6β4 integrin: distinct β4 subunit sites mediate recruitement of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. EMBO J 14: 4470-4481, 1995.
    • (1995) EMBO J , vol.14 , pp. 4470-4481
    • Mainiero, F.1    Pepe, A.2    Wary, K.K.3    Spinardi, L.4    Mohammadi, M.5    Schlessinger, J.6    Giancotti, F.G.7
  • 41
    • 0345178412 scopus 로고
    • Serum-free growth of human mammary epithelial cells: Rapid clonal growth in defined medium and extended serial passage with pituitary extract
    • Hammond SL, Ham RG and Stampfer MR: Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract. Proc Natl Acad Sci USA 81: 5435-5439, 1984.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5435-5439
    • Hammond, S.L.1    Ham, R.G.2    Stampfer, M.R.3
  • 42
    • 0028029124 scopus 로고
    • DNA synthesis-associated nuclear exclusion of p53 in normal human breast epithelial cells in culture
    • Takahashi K and Suzuki K: DNA synthesis-associated nuclear exclusion of p53 in normal human breast epithelial cells in culture. Oncogene 9: 183-188, 1994.
    • (1994) Oncogene , vol.9 , pp. 183-188
    • Takahashi, K.1    Suzuki, K.2
  • 43
    • 0027382021 scopus 로고
    • Association of insulin-like growth-factor-I-induced DNA synthesis with phosphorylation and nuclear exclusion of p53 in human breast cancer MCF-7 cells
    • Takahashi K and Suzuki K: Association of insulin-like growth-factor-I-induced DNA synthesis with phosphorylation and nuclear exclusion of p53 in human breast cancer MCF-7 cells. Int J Cancer 55: 453-458, 1993.
    • (1993) Int J Cancer , vol.55 , pp. 453-458
    • Takahashi, K.1    Suzuki, K.2
  • 44
    • 0030833223 scopus 로고    scopus 로고
    • Loss of density-dependent growth inhibition and dissociation of α-catenin from E-cadherin
    • Tsukatani Y, Suzuki K and Takahashi K: Loss of density-dependent growth inhibition and dissociation of α-catenin from E-cadherin. J Cell Physiol 173: 54-63, 1997.
    • (1997) J Cell Physiol , vol.173 , pp. 54-63
    • Tsukatani, Y.1    Suzuki, K.2    Takahashi, K.3
  • 45
    • 0030847274 scopus 로고    scopus 로고
    • Induction of tyrosine phosphorylation and association of β-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence
    • Takahashi K, Suzuki K and Tsukatani Y: Induction of tyrosine phosphorylation and association of β-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence. Oncogene 15: 71-78, 1997.
    • (1997) Oncogene , vol.15 , pp. 71-78
    • Takahashi, K.1    Suzuki, K.2    Tsukatani, Y.3
  • 46
    • 0030666921 scopus 로고    scopus 로고
    • Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase
    • Dufourny B, Alblas J, van Teeffelen HAAM, van Schaik FMA, van der Burg B, Steenbergh PH and Sussenbach JS: Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J Biol Chem 272: 31163-31171, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 31163-31171
    • Dufourny, B.1    Alblas, J.2    Van Teeffelen, H.A.A.M.3    Van Schaik, F.M.A.4    Van Der Burg, B.5    Steenbergh, P.H.6    Sussenbach, J.S.7
  • 47
    • 0031149810 scopus 로고    scopus 로고
    • Defective expression of β1-integrins in cells with constitutively active αLβ2-integrins
    • Hedman H, Alenius M and Lundgren E: Defective expression of β1-integrins in cells with constitutively active αLβ2-integrins. Exp Cell Res 232: 270-276, 1997.
    • (1997) Exp Cell Res , vol.232 , pp. 270-276
    • Hedman, H.1    Alenius, M.2    Lundgren, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.