-
1
-
-
0023944339
-
Tumor necrosis, cachexia, shock, and inflammation: A common mediator
-
Beutler B, Cerami A (1988) Tumor necrosis, cachexia, shock, and inflammation: A common mediator. Ann Rev Biochem 57:505-518.
-
(1988)
Ann Rev Biochem
, vol.57
, pp. 505-518
-
-
Beutler, B.1
Cerami, A.2
-
2
-
-
0023697978
-
Tumor necrosis factor can induce both apoptotic and necrotic forms of cell lysis
-
Laster SM, Wood JG, Gooding LR (1988) Tumor necrosis factor can induce both apoptotic and necrotic forms of cell lysis. J Immunol 141:2629-2634.
-
(1988)
J Immunol
, vol.141
, pp. 2629-2634
-
-
Laster, S.M.1
Wood, J.G.2
Gooding, L.R.3
-
3
-
-
0026560014
-
Tumor necrosis factor-a activates the sphingomyelin signal transduction pathway in a cell free system
-
Dressler KA, Mathias S, Kolesnick RN (1992) Tumor necrosis factor-a activates the sphingomyelin signal transduction pathway in a cell free system. Science 225:1715-1718.
-
(1992)
Science
, vol.225
, pp. 1715-1718
-
-
Dressler, K.A.1
Mathias, S.2
Kolesnick, R.N.3
-
4
-
-
0023582835
-
Reduced tumor necrosis factor-a induced cytotoxicity by inhibitors of the arachidonic acid metabolism
-
Suffys P, Beyoert R, Van Roy F, Fiers W (1987) Reduced tumor necrosis factor-a induced cytotoxicity by inhibitors of the arachidonic acid metabolism. Biochem Biophys Res Commun 149:735-743.
-
(1987)
Biochem Biophys Res Commun
, vol.149
, pp. 735-743
-
-
Suffys, P.1
Beyoert, R.2
Van Roy, F.3
Fiers, W.4
-
5
-
-
0023616299
-
Tumor cell killing by tumor necrosis factor: Inhibition by anaerobic conditions, free-radical scavengers and inhibitors of arachidonate metabolism
-
Matthews N, Neale ML, Jackson SK, Stark JM (1987) Tumor cell killing by tumor necrosis factor: Inhibition by anaerobic conditions, free-radical scavengers and inhibitors of arachidonate metabolism. Immunology 62:153-155.
-
(1987)
Immunology
, vol.62
, pp. 153-155
-
-
Matthews, N.1
Neale, M.L.2
Jackson, S.K.3
Stark, J.M.4
-
6
-
-
0024582830
-
Oxidative damage in murine tumor cells treated in vitro by recombinant human tumor necrosis factor
-
Zimmerman RJ, Chan A, Leadon SA (1989) Oxidative damage in murine tumor cells treated in vitro by recombinant human tumor necrosis factor. Cancer Res 49:1644-1647.
-
(1989)
Cancer Res
, vol.49
, pp. 1644-1647
-
-
Zimmerman, R.J.1
Chan, A.2
Leadon, S.A.3
-
7
-
-
0013601339
-
The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors
-
Kettelhut IC, Fiers W, Goldberg AL (1987) The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors. Proc Natl Acad Sci USA 84:4273-4277.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 4273-4277
-
-
Kettelhut, I.C.1
Fiers, W.2
Goldberg, A.L.3
-
8
-
-
0028833024
-
Activation of intracellular proteases is an early event in TNF-induced apoptosis
-
Voelkel-Johnson C, Entingh AJ, Wold WSM, Gooding LR, Laster SM (1995) Activation of intracellular proteases is an early event in TNF-induced apoptosis. J Immunol 154:1707-1716.
-
(1995)
J Immunol
, vol.154
, pp. 1707-1716
-
-
Voelkel-Johnson, C.1
Entingh, A.J.2
Wold, W.S.M.3
Gooding, L.R.4
Laster, S.M.5
-
9
-
-
0023819111
-
Cytocidal mechanism of TNF. Effects of lysosomal enzyme and hydroxyl radical inhibition on cytotoxicity
-
Watanabe N, Niitsu Y, Neda H, Sone H, Yamauchi N, Maeda M, Urushizaki I (1988) Cytocidal mechanism of TNF. Effects of lysosomal enzyme and hydroxyl radical inhibition on cytotoxicity. Immunopharmacol Immunotoxicol 10:109-116.
-
(1988)
Immunopharmacol Immunotoxicol
, vol.10
, pp. 109-116
-
-
Watanabe, N.1
Niitsu, Y.2
Neda, H.3
Sone, H.4
Yamauchi, N.5
Maeda, M.6
Urushizaki, I.7
-
10
-
-
0024428198
-
Manganous superoxide dimutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
-
Wong GHW, Elwell JH, Oberly LW, Goeddel DV (1989) Manganous superoxide dimutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor. Cell 58:923-931.
-
(1989)
Cell
, vol.58
, pp. 923-931
-
-
Wong, G.H.W.1
Elwell, J.H.2
Oberly, L.W.3
Goeddel, D.V.4
-
11
-
-
0024202127
-
Induction of manganous superoxide dismutase by tumor necrosis factor: Possible protective mechanism
-
Wong G, Goeddel D (1988) Induction of manganous superoxide dismutase by tumor necrosis factor: Possible protective mechanism. Science 242:941-944.
-
(1988)
Science
, vol.242
, pp. 941-944
-
-
Wong, G.1
Goeddel, D.2
-
12
-
-
0028040019
-
Bcl-2 and the regulation of programmed cell death
-
Reed JC (1994) Bcl-2 and the regulation of programmed cell death. J Cell Biol 124:1-6.
-
(1994)
J Cell Biol
, vol.124
, pp. 1-6
-
-
Reed, J.C.1
-
13
-
-
0026695699
-
Bcl-2: A repressor of lymphocyte death
-
Korsmeyer SJ (1992) Bcl-2: A repressor of lymphocyte death. Immunol Today 13:285-288.
-
(1992)
Immunol Today
, vol.13
, pp. 285-288
-
-
Korsmeyer, S.J.1
-
14
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hokenbery DM, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336.
-
(1990)
Nature
, vol.348
, pp. 334-336
-
-
Hokenbery, D.M.1
Nunez, G.2
Milliman, C.3
Schreiber, R.D.4
Korsmeyer, S.J.5
-
15
-
-
0027485461
-
Bcl2 functions in antioxidant pathway to prevent apoptosis
-
Hokenbery DM, Oltvai ZN, Yin X-M, Milliman CL, Korsmeyer SJ (1993) Bcl2 functions in antioxidant pathway to prevent apoptosis. Cell 75:241-251.
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hokenbery, D.M.1
Oltvai, Z.N.2
Yin, X.-M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
16
-
-
9444243810
-
Shift of the cellular oxidation-reduction potential in neural cells expressing bcl-2
-
Ellerby LM, Ellerby HH, Park SM, Holleran AL, Murphy AN, Fiskum G, Kane DJ, Testa MP, Kayalar C (1996) Shift of the cellular oxidation-reduction potential in neural cells expressing bcl-2. J Neurochem 67:1259-1267.
-
(1996)
J Neurochem
, vol.67
, pp. 1259-1267
-
-
Ellerby, L.M.1
Ellerby, H.H.2
Park, S.M.3
Holleran, A.L.4
Murphy, A.N.5
Fiskum, G.6
Kane, D.J.7
Testa, M.P.8
Kayalar, C.9
-
18
-
-
0030008954
-
2+
-
2+. Oncogene 12: 2259-2266.
-
(1996)
Oncogene
, vol.12
, pp. 2259-2266
-
-
Marin, M.C.1
Fernandez, A.2
Bick, R.J.3
Brisbay, S.4
Buja, L.M.5
Snuggs, M.6
Mconkey, D.J.7
Von Eschenbach, A.L.8
Keating, M.J.9
McDonnell, T.J.10
-
19
-
-
0028939139
-
Programmed cell death and bcl-2 protection in very low oxygen
-
Jacobson MD, Raff DC (1995) Programmed cell death and bcl-2 protection in very low oxygen. Nature 374:814-816.
-
(1995)
Nature
, vol.374
, pp. 814-816
-
-
Jacobson, M.D.1
Raff, D.C.2
-
20
-
-
0029101644
-
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
-
Zamzami N, Marchetti P, Castedo M, Decaudin D, Macho A, Hirsch T, Susin SA, Petit PX, Mignotte B, Kroemer G (1995) Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182:367-377.
-
(1995)
J Exp Med
, vol.182
, pp. 367-377
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
Decaudin, D.4
Macho, A.5
Hirsch, T.6
Susin, S.A.7
Petit, P.X.8
Mignotte, B.9
Kroemer, G.10
-
21
-
-
0027513548
-
Expression of bcl-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor mediated cytotoxicity
-
Hennet T, Bertoni G, Richter C, Peterhans E (1993) Expression of bcl-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor mediated cytotoxicity. Cancer Res 53: 1456-1460.
-
(1993)
Cancer Res
, vol.53
, pp. 1456-1460
-
-
Hennet, T.1
Bertoni, G.2
Richter, C.3
Peterhans, E.4
-
22
-
-
0031037897
-
The release of cytochrome C from mitochondria: A primary site for bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD (1997) The release of cytochrome C from mitochondria: A primary site for bcl-2 regulation of apoptosis. Science 275:1132-1136.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
23
-
-
0028943245
-
Identification of a dual specificity kinase that activates the Jun kinasea and p38-Mpk2
-
Lin A, Minden A, Martinetto H, Claret FX, Lange-Carter C, Mercurio F, Johnson GL, Karin M (1995) Identification of a dual specificity kinase that activates the Jun kinasea and p38-Mpk2. Science 268:286-290.
-
(1995)
Science
, vol.268
, pp. 286-290
-
-
Lin, A.1
Minden, A.2
Martinetto, H.3
Claret, F.X.4
Lange-Carter, C.5
Mercurio, F.6
Johnson, G.L.7
Karin, M.8
-
24
-
-
0029020218
-
Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes
-
Lo YY, Cruz TF (1995) Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes. J Biol Chem 270:11727-11730.
-
(1995)
J Biol Chem
, vol.270
, pp. 11727-11730
-
-
Lo, Y.Y.1
Cruz, T.F.2
-
25
-
-
0028880006
-
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME (1995) Science 270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
26
-
-
0029838165
-
Ordering cell death pathway
-
Park D.S, Stefanis L, Yan CYI, Farinelli SE, Greene LA (1996) Ordering cell death pathway. J Biol Chem 271:21898-21905.
-
(1996)
J Biol Chem
, vol.271
, pp. 21898-21905
-
-
Park, D.S.1
Stefanis, L.2
Yan, C.Y.I.3
Farinelli, S.E.4
Greene, L.A.5
-
27
-
-
0030857126
-
Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of bcl2
-
Park J, Kim I, Oh Y.J, Lee K-w, Han P.-L, Choi E.-J (1997) Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of bcl2. J Biol Chem 272:16725-16728.
-
(1997)
J Biol Chem
, vol.272
, pp. 16725-16728
-
-
Park, J.1
Kim, I.2
Oh, Y.J.3
Lee, K.-W.4
Han, P.-L.5
Choi, E.-J.6
-
28
-
-
0027406443
-
Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity
-
Vanhaesebroeck B, Reed JC, De Valck D, Grooten J, Miyashita T, Tanaka S, Beyaert R, Van Roy F, Fiers W (1993) Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity. Oncogene 8:1075-1081.
-
(1993)
Oncogene
, vol.8
, pp. 1075-1081
-
-
Vanhaesebroeck, B.1
Reed, J.C.2
De Valck, D.3
Grooten, J.4
Miyashita, T.5
Tanaka, S.6
Beyaert, R.7
Van Roy, F.8
Fiers, W.9
-
29
-
-
0028912996
-
Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: Protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA
-
Talley AK, Dewhurst S, Perry SW, Dollard SC, Gummuluru S, Fine SM, New D, Epstein LG, Gendelma HE, Gelbard HA (1995) Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: Protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. Mol Cell Biol 15: 2359-2366.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2359-2366
-
-
Talley, A.K.1
Dewhurst, S.2
Perry, S.W.3
Dollard, S.C.4
Gummuluru, S.5
Fine, S.M.6
New, D.7
Epstein, L.G.8
Gendelma, H.E.9
Gelbard, H.A.10
-
30
-
-
0027161158
-
Effects of bcl-2 on Fas antigen-mediated cell death
-
Itoh N, Tsujimoto Y, Nogata S (1993) Effects of bcl-2 on Fas antigen-mediated cell death. J Immunol 15:621-627.
-
(1993)
J Immunol
, vol.15
, pp. 621-627
-
-
Itoh, N.1
Tsujimoto, Y.2
Nogata, S.3
-
33
-
-
0030581699
-
Ceramide reproduces late appearance of oxidative stress during TNF-mediated cell death in L929 cells
-
Gomez EO, Mendoza-Milla C, Ibarra-Sanchez MJ, Ventura-Gallegos JL, Zentella A (1996) Ceramide reproduces late appearance of oxidative stress during TNF-mediated cell death in L929 cells. Biochem Biophys Res Commun 228:505-509.
-
(1996)
Biochem Biophys Res Commun
, vol.228
, pp. 505-509
-
-
Gomez, E.O.1
Mendoza-Milla, C.2
Ibarra-Sanchez, M.J.3
Ventura-Gallegos, J.L.4
Zentella, A.5
-
34
-
-
0026713818
-
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation
-
Schulze-Osthoff K, Bakker AC, Vanhaesebroeck B, Beyaert R, Jacob WA, Fiers WJ (1992) Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. Biol Chem 267:5317-5323.
-
(1992)
Biol Chem
, vol.267
, pp. 5317-5323
-
-
Schulze-Osthoff, K.1
Bakker, A.C.2
Vanhaesebroeck, B.3
Beyaert, R.4
Jacob, W.A.5
Fiers, W.J.6
-
35
-
-
0029849215
-
Bcl2 prevents CD95-induced degradation of lamin B and poly (ADP-ribose)polymerase and restores the NF-B signaling pathway
-
Mandai M, Maggirwar SB, Sharma N, Kaufmann SH, Sun SC, Kumar R (1996) Bcl2 prevents CD95-induced degradation of lamin B and poly (ADP-ribose)polymerase and restores the NF-B signaling pathway. J Biol Chem 271:30354-30359.
-
(1996)
J Biol Chem
, vol.271
, pp. 30354-30359
-
-
Mandai, M.1
Maggirwar, S.B.2
Sharma, N.3
Kaufmann, S.H.4
Sun, S.C.5
Kumar, R.6
-
36
-
-
0029976817
-
An essential role for NF-kappa B in preventing TNF-alpha induced cell death
-
Beg A, Baltimore D (1996) An essential role for NF-kappa B in preventing TNF-alpha induced cell death. Science 274:782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.1
Baltimore, D.2
-
37
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
38
-
-
0021288861
-
Assay of superoxide dismutase activity in tumor tissue
-
Oberly LW, Spitz DR (1994) Assay of superoxide dismutase activity in tumor tissue. Meth Enzymol 105:457-464.
-
(1994)
Meth Enzymol
, vol.105
, pp. 457-464
-
-
Oberly, L.W.1
Spitz, D.R.2
-
39
-
-
0018639079
-
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
-
Chirgwin JM, Przybyla AE, McDonald RJ, Rutter WJ (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochem 18:5294-5299.
-
(1979)
Biochem
, vol.18
, pp. 5294-5299
-
-
Chirgwin, J.M.1
Przybyla, A.E.2
McDonald, R.J.3
Rutter, W.J.4
-
40
-
-
0028893492
-
Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
-
Greenlund LJS, Deckwerth TL, Johnson EM (1995) Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death. Neuron 14:303-315.
-
(1995)
Neuron
, vol.14
, pp. 303-315
-
-
Greenlund, L.J.S.1
Deckwerth, T.L.2
Johnson, E.M.3
|