Allelic imbalance at chromosome region 11q23 in cervical carcinomas

European Journal of Cancer

Volumn 35, Issue 4, 1999, Pages 659-663

  Skomedal, H ^a   Helland, Å ^a   Kristensen, G B ^a   Holm, R ^a   Borresen Dale A L ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Allelic imbalance; Ataxia telangiectasia; Cervical cancer; Chromosome 11; TP53

Indexed keywords

MICROSATELLITE DNA; PROTEIN P53;

ADULT; AGED; ALLELE; ARTICLE; CARCINOGENESIS; CHROMOSOME 11Q; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE MAPPING; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; ATAXIA TELANGIECTASIA; CHROMOSOMES, HUMAN, PAIR 11; FEMALE; GENE DELETION; HUMANS; MIDDLE AGED; PROGNOSIS; UTERINE CERVICAL NEOPLASMS;

EID: 0033118537     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(98)00413-4     Document Type: Article

References (19)

1. zur Hausen H. Papillomaviruses in human cancer. Cancer. 59:1987;1692-1696.
2. Lasko D., Cavenee W., Nordenskjold M. Loss of constitutional heterozygosity in human cancer. Annu. Rev. Genet. 25:1991;281-314.
3. Hampton G.M., Penny L.A., Baergen R.N., et al. Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24. Proc. Natl. Acad. Sci. USA. 91:1994;6953-6957.
4. Bethwaite P.B., Koreth J., Herrington C.S., McGee J.O. Loss of heterozygosity occurs at the D11S29 locus on chromosome 11q23 in invasive cervical carcinoma. Br. J. Cancer. 71:1995;814-828.
5. Gabra H., Watson J.E., Taylor K.J., et al. Definition and refinement of a region of loss of heterozygosity at 11q23.3-q24.3 in epithelial ovarian cancer associated with poor prognosis. Cancer Res. 56:1996;950-954.
6. Laake K., Odegård Å., Andersen T.I., et al. Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM. Genes Chromosom. Cancer. 8:1997;175-180.
7. Gustafson C.E., Young J., Leggett B., Searle J., Chenevix-Trench G. Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours. Br. J. Cancer. 70:1994;395-397.
8. Herbst R.A., Larson A., Weiss J., Cavenee W.K., Hampton G.M., Arden K.C. A defined region of loss of heterozygosity at 11q23 in cutaneous malignant melanoma. Cancer Res. 55:1995;2494-2496.
9. Savitsky K., Sfez S., Tagle D.A., et al. The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum. Mol. Genet. 4:1995;2025-2032.
10. Swift M., Morrell D., Massey R.B., Chase C.L. Incidence of cancer in 161 families affected by ataxia-telangiectasia. N. Engl. J. Med. 325:1991;1831-1836.
11. Kastan M.B., Zhan Q., el-Deiry W.S., et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell. 71:1992;587-597.
12. Helland A., Holm R., Kristensen G., et al. Genetic alterations of the TP53 gene, p53 protein expression and HPV infection in primary cervical carcinomas. J. Pathol. 171:1993;105-114.
13. Momand J., Zambetti G.P., Olson D.C., George D., Levine A.J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell. 69:1992;1237-1245.
14. Vanagaite L., Savitsky K., Rotman G., et al. Physical localization of microsatellite markers at the ataxia-telangiectasia locus at 11q22-q23. Genomics. 22:1994;231-233.
15. Vanagaite L., James M.R., Rotman G., et al. A high-density microsatellite map of the ataxia-telangiectasia locus. Hum. Genet. 95:1995;451-454.
16. Helland A., Borresen-Dale A.L., Peltomaki P., et al. Microsatellite instability in cervical and endometrial carcinomas. Int. J. Cancer. 70:1997;499-501.
17. Teale B., Khanna K.K., Singh S.P., Lavin M.F. Radiation-activated DNA-binding protein constitutively present in ataxia telangiectasia nuclei. J. Biol. Chem. 268:1993;22450-22455.
18. Renzing J., Hansen S., Lane D.P. Oxidative stress is involved in the UV activation of p53. J. Cell. Sci. 109:1996;1105-1112.
19. Larson A.A., Kern S., Sommers R.L., Yokota J., Cavenee W.K., Hampton G.M. Analysis of replication error (RER+) phenotypes in cervical carcinoma. Cancer Res. 56:1996;1426-1431.