Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice

Transgenic Research

Volumn 8, Issue 2, 1999, Pages 125-135

  De Groot, Nanda ^a   Van Kuik Romeijn, Petra ^a   Lee, Sang He ^a   De Boer, Herman A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Mammary gland; Over expression; Polymeric immunoglobulin receptor; Secretory component; Secretory IgA; Transgenic mice

Indexed keywords

GENE EXPRESSION; IMMUNOGLOBULIN GENE; MAMMARY GLAND; TRANSGENIC ANIMAL;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CATTLE; CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; IMMUNOGLOBULIN A, SECRETORY; LACTATION; MAMMARY GLANDS, ANIMAL; MICE; MICE, TRANSGENIC; MILK; RECEPTORS, POLYMERIC IMMUNOGLOBULIN; SECRETORY COMPONENT; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 0033117463     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008981312682     Document Type: Article

References (43)

1. Brandtzaeg P (1983) The secretory immune system of lactating human mammary glands compared with other exocrine organs. Ann NY Acad Sci 409: 353-383.
2. Brandtzaeg P, Nilssen DE, Rognum TO and Thrane PS (1991) Ontogeny of the mucosal immune system and IgA deficiency. Gastroenterol Clin North Am 20: 397-439.
3. Brem G, Hartl P, Besenfelder U, Wolf E, Zinovieva N and Pfaller R (1994) Expression of synthetic cDNA sequences encoding human insulin-like growth factor-1 (IGF-1) in the mammary gland of transgenic rabbits. Gene 149: 351-355.
4. Bijvoet AGA, Kroos MA, Pieper FR, van der Vliet M, de Boer HA, van der Ploeg AT, Verbeet MPh and Reuser AJJ (1998) Recombinant human acid α-glucosidase: High level production in mouse milk, biochemical characteristics, correction of enzyme deficiency in GSDII KO mice. Hum Mol Genet 7: 1815-1824.
5. Childers NK, Bruce MG and McGhee JR (1989) Molecular mechanisms of immunoglobulin A defense. Annu Rev Microbiol 43: 503-536.
6. Chomczynski P Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
7. Chomczynski P (1992) One-hour downward alkaline capillary transfer for blotting of DNA and RNA. Anal Biochem 201: 134-139.
8. Eiffert H, Quentin E, Wiederhold M, Hillemeir S, Decker J, Weber M and Hilschmann N (1991) Determination of the molecular structure of the human free secretory component. Biol Chem Hoppe-Seyler 372: 119-128.
9. Goldblum RM and Goldman AS (1994) Immunological components of milk: Formation and function. In: Goldblum RM, Goldman, AS, Ogra PL, Lamm ME, McGhee JR, Mestecky J, Strober W and Bienenstock J (eds). Handbook of Mucosal Immunology (pp. 643-652) Academic Press.
10. Hayashi M, Takenouchi N, Asano M, Kato M, Tsurumachi T, Saito T and Moro I (1997) The polymeric immunoglobulin receptor (secretory component) in a human intestinal epithelial cell line is up-regulated by interleukin-1. Immunol 92: 220-225.
11. Hennighausen LG and Sippel AE (1992) Characterization and cloning of the mRNAs specific for the lactating mouse mammary gland. Eur J Biochem 125: 131-141.
12. Hirt RP, Hughes GJ, Frutiger S, Michetti P, Perregaux C, Poulain-Godefroy O, Jeanguenat N, Neutra MR and Krachenbuhl J-P (1993) Transcytosis of the polymeric Ig receptor requires phosphorylation of serine 664 in the absence but not the presence of dimeric IgA. Cell 74: 245-255.
13. Hogan B, Costantini F and Lacy E (1986) Manipulating the Mouse Embryo: A Laboratory Manual. NY: Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
14. Kaetzel CS, Robinson JK, Chintalacharuvu KR, Vaerman J-P and Lamm ME (1991) The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: A local defense function for IgA. Proc Natl Acad Sci USA 88: 8796-8800.
15. Konings RN, Verhoeven EJ and Peeters BP (1987) pKUN, vectors for the separate production of both DNA strands of recombinant plasmids. Methods Enzymol 153: 12-34.
16. Krachenbuhl J-P and Neutra MR (1992) Molecular and cellular basis of immune protection of mucosal surfaces. Phys Rev 72: 853-879.
17. Krajci P, Solberg R, Sandberg M, Oyen O, Jahnsen T and Brandtzaeg P (1989) Molecular cloning of the human transmembrane secretory component (poly-Ig receptor) and its mRNA expression in human tissues. Biochem Biophys Res Commun 158: 783-789.
18. Kvale D, Lovhaug D, Sollid LM and Brandtzaeg P (1988) Tumor necrosis factor-α up-regulates expression of secretory component, the epithelial receptor for polymeric immunoglobulins. J Immunol 140: 3086-3089.
19. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
20. Laird PW, Zijderveld A, Linders K, Rudnicki MA, Jaenisch R and Berns A (1991) Simplified mammalian DNA isolation procedure. Nucleic Acids Res 19: 4293.
21. Lamm ME (1997) Interaction of antigens and antibodies at mucosal surfaces. Annu Rev Microbiol 51: 311-340.
22. Mazanee MB, Kaetzel CS, Lamm ME, Fletcher D and Nedrud JG (1992) Intracellular neutralization of virus by immunoglobulin A antibodies. Proc Natl Acad Sci USA 89: 6901-6905
23. Mazanee MB, Nedrud JG, Kaetzel CS and Lamm ME (1993) A three-tiered view of the role of IgA in mucosal defense. Immunol Today 14: 430-435.
24. s1-casein gene sequences direct high level expression of active human urokinase in mouse milk. Bio/Technology 8: 443-446.
25. Mostov KE, Friedlander M and Blobel G (1984) The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains. Nature 308: 37-43.
26. Mostov KE and Deitcher DL (1986) Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA Cell 46: 613-621.
27. Mostov KE (1994) Transepithelial transport of immunoglobulins. Annu Rev Immunol 12: 63-84.
28. Nuijens JH, van Berkel PHC and Schanbacher FL (1996) Structure and biological actions of lactoferrin. J Mammary Gland Biol Neoplasia 1: 285-295.
29. Okamoto CT, Shia S-P, Bird C, Mostov KE and Roth MG (1992) The cytoplasmic domain of the polymeric immunoglobulin receptor contains two internalization signals that are distinct from its basolateral sorting signal. J Biol Chem 267: 9925-9932.
30. Parr EL, Bozzola JJ and Parr MB (1995) Purification and measurement of secretory IgA in mouse milk. J Immunol Methods 180: 147-157.
31. Phillips JO, Everson MP, Moldoveanu Z, Lue C and Mestecky J (1990) Synergistic effect of IL-4 and IFN-γ on the expression of polymeric Ig receptor (secretory component) and IgA binding by human epithelial cells. J Immunol 145: 1740-1744.
32. Pinkert CA (1994) Transgenic Animal Technology: A Laboratory Handbook. Academic Press, San Diego.
33. Piskurich JF, France JA, Tamer CM, Willmer CA, Kaetzel CS and Kaetzel DM (1993) lnterferon-γ induces polymeric immunoglobulin receptor mRNA in human intestinal epithelial cells by a protein synthesis dependent mechanism. Mol Immunol 30: 413-421.
34. Piskurich JF, Blanchard MH, Youngman KR, France JA and Kaetzel CS (1995) Molecular cloning of the mouse polymeric Ig receptor. Functional regions of the molecule are conserved among five mammalian species. J Immunol 154: 1735-1747.
35. Platenburg GJ, Kootwijk EPA, Kooiman PM, Woloshuk SL, Nuijens JH, Krimpenfort PJA, Pieper FR, de Boer HA and Strijker R (1994) Expression of human lactoferrin in milk of transgenic mice. Transgenic Res 3: 99-108.
36. Reich V, Mostov K and Aroeti B (1996) The basolateral sorting signal of the polymeric immunoglobulin receptor contains two functional domains. J Cell Sci 109: 2133-2139.
37. s1-casein gene in milk of transgenic mice. Transgenic Res 6: 1-10.
38. Sambrook J, Fritsch EF and Maniatis T (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
39. Sanger F, Nieklen S and Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-5467.
40. Song W, Bomsel M, Casanova J, Vaerman J-P and Mostov K (1994) Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA. Proc Natl Acad Sci USA 91: 163-166.
41. Stevenson EM and Leaver J (1994) Chromatographic separation of the proteins of mouse milk. Int Dairy J 4: 205-220.
42. Thorpe GHG and Kricka IJ (1986) Enhanced chemiluminescent reactions catalyzed by horseradish peroxidase. Methods Enzymol 133: 331-353.
43. s1-casein gene sequences direct high level expression of human granulocyte-macrophage colony-stimulating factor in the milk of transgenic mice. Transgenic Res 6: 75-84.