메뉴 건너뛰기




Volumn 36, Issue 1, 1999, Pages 81-99

Cyclodextrins in transdermal and rectal delivery

Author keywords

Complexation; Cyclodextrin; Drug absorption; Drug delivery; Drug release; Local irritation; Permeability; Rectum; Skin; Stability constant

Indexed keywords

COMPLEXATION; DERIVATIVES; DRUG INFUSION; DRUG PRODUCTS; MECHANICAL PERMEABILITY; SKIN;

EID: 0033106031     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(98)00056-8     Document Type: Review
Times cited : (199)

References (81)
  • 2
    • 0031054513 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. 3. Toxicological issues and safety evaluation
    • T. Irie, K. Uekama, Pharmaceutical applications of cyclodextrins. 3. Toxicological issues and safety evaluation, J. Pharm. Sci. 86 (1997) 147-162.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 147-162
    • Irie, T.1    Uekama, K.2
  • 3
    • 0023801431 scopus 로고
    • Improvement in availability and stability of a dermacorticoid by inclusion in β-cyclodextrin
    • F. Glomot, L. Benkerrour, D. Duchêne, M.-C. Poelman, Improvement in availability and stability of a dermacorticoid by inclusion in β-cyclodextrin, Int. J. Pharm. 46 (1988) 49-55.
    • (1988) Int. J. Pharm. , vol.46 , pp. 49-55
    • Glomot, F.1    Benkerrour, L.2    Duchêne, D.3    Poelman, M.-C.4
  • 4
    • 0026546060 scopus 로고
    • 1 through hairless mouse skin: Combined use of carboxymethyl-ethyl-β-cyclodextrin and penetration enhancers
    • 1 through hairless mouse skin: combined use of carboxymethyl-ethyl-β-cyclodextrin and penetration enhancers, J. Pharm. Pharmacol. 44 (1992) 119-121.
    • (1992) J. Pharm. Pharmacol. , vol.44 , pp. 119-121
    • Uekama, K.1    Adachi, H.2    Irie, T.3    Yano, T.4    Saita, M.5    Noda, K.6
  • 5
    • 0026651913 scopus 로고
    • Stabilization of prostaglandin E1 in fatty alcohol propylene glycol ointment by acidic cyclodextrin derivatives, O-carboxymethyl-O-ethyl-β-cyclodextrin
    • H. Adachi, T. Irie, F. Hirayama, K. Uekama, Stabilization of prostaglandin E1 in fatty alcohol propylene glycol ointment by acidic cyclodextrin derivatives, O-carboxymethyl-O-ethyl-β-cyclodextrin, Chem. Pharm. Bull. 40 (1992) 1586-1591.
    • (1992) Chem. Pharm. Bull. , vol.40 , pp. 1586-1591
    • Adachi, H.1    Irie, T.2    Hirayama, F.3    Uekama, K.4
  • 7
    • 0025221542 scopus 로고
    • Enhancement of the antiinflammatory effect of ethyl 4-biphenyl acetate in ointment by β-cyclodextrin derivatives: Increased absorption and localized activation of the prodrug in rats
    • H. Arima, H. Adachi, T. Irie, K. Uekama, J. Pitha, Enhancement of the antiinflammatory effect of ethyl 4-biphenyl acetate in ointment by β-cyclodextrin derivatives: Increased absorption and localized activation of the prodrug in rats, Pharm. Res. 7 (1990) 1152-1156.
    • (1990) Pharm. Res. , vol.7 , pp. 1152-1156
    • Arima, H.1    Adachi, H.2    Irie, T.3    Uekama, K.4    Pitha, J.5
  • 8
    • 0031973898 scopus 로고    scopus 로고
    • Enhancing effect of hydroxypropyl-β-cyclodextrin on cutaneous penetration and activation of ethyl 4-biphenylyl acetate in hairless mouse skin
    • H. Arima, T. Miyaji, T. Irie, F. Hirayama, K. Uekama, Enhancing effect of hydroxypropyl-β-cyclodextrin on cutaneous penetration and activation of ethyl 4-biphenylyl acetate in hairless mouse skin, Eur. J. Pharm. Sci. 6 (1998) 53-59.
    • (1998) Eur. J. Pharm. Sci. , vol.6 , pp. 53-59
    • Arima, H.1    Miyaji, T.2    Irie, T.3    Hirayama, F.4    Uekama, K.5
  • 9
    • 0031950153 scopus 로고    scopus 로고
    • Preparation, characterization, and evaluation of miconazole-cyclodextrin complexes for improved oral and topical delivery
    • S. Tenjarla, P. Puranajoti, R. Kasina, T. Mandai, Preparation, characterization, and evaluation of miconazole-cyclodextrin complexes for improved oral and topical delivery, J. Pharm. Sci. 87 (1998) 425-429.
    • (1998) J. Pharm. Sci. , vol.87 , pp. 425-429
    • Tenjarla, S.1    Puranajoti, P.2    Kasina, R.3    Mandai, T.4
  • 10
    • 0026334111 scopus 로고
    • Release of ketoprofen from dermal bases in the presence of cyclodextrins:effect of the affinity constant determined in semisolid vehicles
    • I. Orienti, V. Zecchi, V. Bertasi, A. Fini, Release of ketoprofen from dermal bases in the presence of cyclodextrins:effect of the affinity constant determined in semisolid vehicles, Arch. Pharm. 324 (1991) 943-947.
    • (1991) Arch. Pharm. , vol.324 , pp. 943-947
    • Orienti, I.1    Zecchi, V.2    Bertasi, V.3    Fini, A.4
  • 12
    • 0026444016 scopus 로고
    • Evaluation of few ciprofloxacin (CIP) and norfloxacin (NOR) formulations
    • N. Udupa, L. Bhat, Evaluation of few ciprofloxacin (CIP) and norfloxacin (NOR) formulations, Drug. Dev. Ind. Pharm. 18 (1992) 2197-2205.
    • (1992) Drug. Dev. Ind. Pharm. , vol.18 , pp. 2197-2205
    • Udupa, N.1    Bhat, L.2
  • 13
    • 0021265362 scopus 로고
    • Effects of β-and γ-cyclodextrins on release of betamethasone from ointment bases
    • M. Otagiri, T. Fujinaga, A. Sakai, K. Uekama, Effects of β-and γ-cyclodextrins on release of betamethasone from ointment bases, Chem. Pharm. Bull. 32 (1984) 2401-2405.
    • (1984) Chem. Pharm. Bull. , vol.32 , pp. 2401-2405
    • Otagiri, M.1    Fujinaga, T.2    Sakai, A.3    Uekama, K.4
  • 14
    • 0021801519 scopus 로고
    • Improvement in the percutaneous absorption of beclomethasone dipropionate by γ-cyclodextrin complexation
    • K. Uekama, M. Otagiri, A. Sakai, T. Irie, N. Matsuo, Y. Matsuoka, Improvement in the percutaneous absorption of beclomethasone dipropionate by γ-cyclodextrin complexation, J. Pharm. Pharmacol. 37 (1985) 532-535.
    • (1985) J. Pharm. Pharmacol. , vol.37 , pp. 532-535
    • Uekama, K.1    Otagiri, M.2    Sakai, A.3    Irie, T.4    Matsuo, N.5    Matsuoka, Y.6
  • 15
    • 0023197562 scopus 로고
    • Improvement in percutaneous absorption of prednisolone by β- and γ-cyclodextrin complexations
    • K. Uekama, K. Arimori, A. Sakai, K. Masaki, T. Irie, M. Otagiri, Improvement in percutaneous absorption of prednisolone by β- and γ-cyclodextrin complexations, Chem. Pharm. Bull. 35 (1987) 2910-2913.
    • (1987) Chem. Pharm. Bull. , vol.35 , pp. 2910-2913
    • Uekama, K.1    Arimori, K.2    Sakai, A.3    Masaki, K.4    Irie, T.5    Otagiri, M.6
  • 16
    • 0023221391 scopus 로고
    • Effects of β- and dimethyl-β-cyclodextrins on release and percutaneous absorption behaviors of prednisolone from some ointment bases
    • K. Uekama, K. Masaki, K. Arimori, T. Irie, F. Hirayama, Effects of β- and dimethyl-β-cyclodextrins on release and percutaneous absorption behaviors of prednisolone from some ointment bases, Yakugaku Zasshi 107 (1987) 449-456.
    • (1987) Yakugaku Zasshi , vol.107 , pp. 449-456
    • Uekama, K.1    Masaki, K.2    Arimori, K.3    Irie, T.4    Hirayama, F.5
  • 17
    • 0025064973 scopus 로고
    • Improved drug delivery through the skin by hydrophilic β-cyclodextrins. Enhancement of anti-inflammatory effect of 4-biphenylylacetic acid in rats
    • H. Arima, H. Adachi, T. Irie, K. Uekama, Improved drug delivery through the skin by hydrophilic β-cyclodextrins. Enhancement of anti-inflammatory effect of 4-biphenylylacetic acid in rats, Drug Invest. 2 (1990) 155-161.
    • (1990) Drug Invest. , vol.2 , pp. 155-161
    • Arima, H.1    Adachi, H.2    Irie, T.3    Uekama, K.4
  • 18
    • 0029972468 scopus 로고    scopus 로고
    • Possible enhancing mechanism of the cutaneous permeation of 4-biphenylylacetic acid by β-cyclodextrin derivatives in hydrophilic ointment
    • H. Arima, T. Miyaji, T. Irie, F. Hirayama, K. Uekama, Possible enhancing mechanism of the cutaneous permeation of 4-biphenylylacetic acid by β-cyclodextrin derivatives in hydrophilic ointment, Chem. Pharm. Bull. 44 (1996) 582-586.
    • (1996) Chem. Pharm. Bull. , vol.44 , pp. 582-586
    • Arima, H.1    Miyaji, T.2    Irie, T.3    Hirayama, F.4    Uekama, K.5
  • 19
    • 0028362741 scopus 로고
    • Drug carriers for transdermal preparations of flurbiprofen
    • U.V. Singh, S. Pandey, N. Udupa, Drug carriers for transdermal preparations of flurbiprofen, Drug Dev. Ind. Pharm. 20 (1994) 1811-1820.
    • (1994) Drug Dev. Ind. Pharm. , vol.20 , pp. 1811-1820
    • Singh, U.V.1    Pandey, S.2    Udupa, N.3
  • 20
    • 0027416927 scopus 로고
    • Formulation and evaluation of oral and transdermal preparations of flurbiprofen and piroxicam incorporated with different carriers
    • R.D. Narashima, N. Udupa, Formulation and evaluation of oral and transdermal preparations of flurbiprofen and piroxicam incorporated with different carriers, Drug. Dev. Ind. Pharm. 19 (1993) 843-852.
    • (1993) Drug. Dev. Ind. Pharm. , vol.19 , pp. 843-852
    • Narashima, R.D.1    Udupa, N.2
  • 21
    • 0028324016 scopus 로고
    • In-vivo evaluation of indomethacin/cyclodextrin complexes Gastrointestinal tolerance and dermal anti-inflammatory activity
    • S.Z. Lin, D. Wouessidjewe, M.C. Poelman, D. Duchêne, In-vivo evaluation of indomethacin/cyclodextrin complexes Gastrointestinal tolerance and dermal anti-inflammatory activity, Int. J. Pharm. 106 (1994) 63-67.
    • (1994) Int. J. Pharm. , vol.106 , pp. 63-67
    • Lin, S.Z.1    Wouessidjewe, D.2    Poelman, M.C.3    Duchêne, D.4
  • 22
    • 0002086622 scopus 로고
    • Physical chemical analysis of percutaneous absorption process from creams and ointments
    • T. Higuchi, Physical chemical analysis of percutaneous absorption process from creams and ointments, J. Soc. Cosmet. Chem. 11 (1960) 85-97.
    • (1960) J. Soc. Cosmet. Chem. , vol.11 , pp. 85-97
    • Higuchi, T.1
  • 24
    • 0027244711 scopus 로고
    • In-vivo skin pharmacokinetics of liarozole: Percutaneous absorption studies with different formulations of cyclodextrin derivatives in rats
    • U. Vollmer, B.W. Müller, J. Mesens, B. Wilffert, T. Peters, In-vivo skin pharmacokinetics of liarozole: Percutaneous absorption studies with different formulations of cyclodextrin derivatives in rats, Int. J. Pharm. 99 (1993) 51-58.
    • (1993) Int. J. Pharm. , vol.99 , pp. 51-58
    • Vollmer, U.1    Müller, B.W.2    Mesens, J.3    Wilffert, B.4    Peters, T.5
  • 26
    • 0029564835 scopus 로고
    • The effect of polyvinylpyrrolidone on cyclodextrin complexation of hydrocortisone and its diffusion through hairless mouse skin
    • A.M. Sigurôardóttir, T. Loftsson, The effect of polyvinylpyrrolidone on cyclodextrin complexation of hydrocortisone and its diffusion through hairless mouse skin, Int. J. Pharm. 126 (1995) 73-78.
    • (1995) Int. J. Pharm. , vol.126 , pp. 73-78
    • Sigurôardóttir, A.M.1    Loftsson, T.2
  • 27
    • 0028130570 scopus 로고
    • The effect of polyvinylpyrrolidone and hydroxypropyl methylcellulose on hydroxypropyl-β-cyclodextrin complexation of hydrocortisone and its permeability through hairless mouse skin
    • T. Loftsson, A.M. Sigurôardóttir, The effect of polyvinylpyrrolidone and hydroxypropyl methylcellulose on hydroxypropyl-β-cyclodextrin complexation of hydrocortisone and its permeability through hairless mouse skin, Eur. J. Pharm. Sci. 2 (1994) 297-301.
    • (1994) Eur. J. Pharm. Sci. , vol.2 , pp. 297-301
    • Loftsson, T.1    Sigurôardóttir, A.M.2
  • 28
    • 0028265697 scopus 로고
    • The effect of hydroxypropyl methylcellulose on the release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulations
    • T. Loftsson, H. Friôriksdóttir, S. Thórisdóttir, E. Stefánsson, The effect of hydroxypropyl methylcellulose on the release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulations, Int. J. Pharm. 104 (1994) 181-184.
    • (1994) Int. J. Pharm. , vol.104 , pp. 181-184
    • Loftsson, T.1    Friôriksdóttir, H.2    Thórisdóttir, S.3    Stefánsson, E.4
  • 29
    • 0025000366 scopus 로고
    • Effect of diethyl-β-cyclodextrin on the release of nitroglycerin from formulations
    • M. Umemura, H. Ueda, K. Tomono, T. Nagai, Effect of diethyl-β-cyclodextrin on the release of nitroglycerin from formulations, Drug Des. Deliv. 6 (1990) 297-310.
    • (1990) Drug Des. Deliv. , vol.6 , pp. 297-310
    • Umemura, M.1    Ueda, H.2    Tomono, K.3    Nagai, T.4
  • 30
    • 0343862856 scopus 로고
    • Effect of β-cyclodextrins on sustained release of nitorglycerin from ointment bases
    • K. Tomono, H. Gotoh, M. Okamura, M. Horioka, H. Ueda, T. Nagai, Effect of β-cyclodextrins on sustained release of nitorglycerin from ointment bases, Yakuzaigaku 51 (1991) 22-28.
    • (1991) Yakuzaigaku , vol.51 , pp. 22-28
    • Tomono, K.1    Gotoh, H.2    Okamura, M.3    Horioka, M.4    Ueda, H.5    Nagai, T.6
  • 31
    • 0027074712 scopus 로고
    • Effect of diethyl β-cyclodextrin on the release and absorption behaviour of indomethacin from ointment bases
    • K. Kawahara, H. Ueda, K. Tomono, T. Nagai, Effect of diethyl β-cyclodextrin on the release and absorption behaviour of indomethacin from ointment bases, STP Pharm. Sci. 2 (1992) 506-513.
    • (1992) STP Pharm. Sci. , vol.2 , pp. 506-513
    • Kawahara, K.1    Ueda, H.2    Tomono, K.3    Nagai, T.4
  • 33
    • 0023574288 scopus 로고
    • Enhanced percutaneous absorption of homogenized tolnaftate/β-cyclodextrin polymer ground mixture
    • J. Szeman, H. Ueda, J. Szejtli, et al., Enhanced percutaneous absorption of homogenized tolnaftate/β-cyclodextrin polymer ground mixture, Drug Des. Deliv. 1 (1987) 325-332.
    • (1987) Drug Des. Deliv. , vol.1 , pp. 325-332
    • Szeman, J.1    Ueda, H.2    Szejtli, J.3
  • 34
    • 0028880786 scopus 로고
    • Effects of β-cyclodextrins on skin: Implications for the transdermal delivery of piribedil and a novel cognition enhancing-drug, S-9977
    • J.Y. Legendre, I. Rault, W. Luijten, I. Demuynck, S. Horvath, Effects of β-cyclodextrins on skin: Implications for the transdermal delivery of piribedil and a novel cognition enhancing-drug, S-9977, Eur. J. Pharm. Sci. 3 (1995) 311-322.
    • (1995) Eur. J. Pharm. Sci. , vol.3 , pp. 311-322
    • Legendre, J.Y.1    Rault, I.2    Luijten, W.3    Demuynck, I.4    Horvath, S.5
  • 35
    • 0022592642 scopus 로고
    • Effects of β-cyclodextrin and di-O-methyl-β-cyclodextrin on the percutaneous absorption of butylparaben, indomethacin and sulfanilic acid
    • H. Okamoto, H. Komatsu, M. Hashida, H. Sezaki, Effects of β-cyclodextrin and di-O-methyl-β-cyclodextrin on the percutaneous absorption of butylparaben, indomethacin and sulfanilic acid, Int. J. Pharm. 30 (1986) 35-45.
    • (1986) Int. J. Pharm. , vol.30 , pp. 35-45
    • Okamoto, H.1    Komatsu, H.2    Hashida, M.3    Sezaki, H.4
  • 36
    • 0024469572 scopus 로고
    • Effects of 2-hydroxypropyl-β-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17β-estradiol
    • T. Loftsson, N. Bodor, Effects of 2-hydroxypropyl-β-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17β-estradiol, Acta Pharm. Nord. 1 (1989) 185-194.
    • (1989) Acta Pharm. Nord. , vol.1 , pp. 185-194
    • Loftsson, T.1    Bodor, N.2
  • 37
    • 0030988199 scopus 로고    scopus 로고
    • Characterization of the influence of some cyclodextrins on the stratum corneum from the hairless mouse
    • M. Vitória, L.B. Bentley, R.F. Vianna, S. Wilson, J. Collett, Characterization of the influence of some cyclodextrins on the stratum corneum from the hairless mouse, J. Pharm. Pharmacol. 49 (1997) 397-402.
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 397-402
    • Vitória, M.1    Bentley, L.B.2    Vianna, R.F.3    Wilson, S.4    Collett, J.5
  • 38
    • 0028853308 scopus 로고
    • Improved acitretin delivery through hairless mouse skin by cyclodextrin complexation
    • T. Loftsson, A.M. Sigurôardóttir, J.H. Olafsson, Improved acitretin delivery through hairless mouse skin by cyclodextrin complexation, Int. J. Pharm. 115 (1995) 255-258.
    • (1995) Int. J. Pharm. , vol.115 , pp. 255-258
    • Loftsson, T.1    Sigurôardóttir, A.M.2    Olafsson, J.H.3
  • 39
    • 0026461148 scopus 로고
    • 1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: Optimized topical formulation with β-cyclodextrin derivative and penetration enhancer HPE-101
    • 1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with β-cyclodextrin derivative and penetration enhancer HPE-101, J. Pharm. Pharmacol. 44 (1992) 1033-1035.
    • (1992) J. Pharm. Pharmacol. , vol.44 , pp. 1033-1035
    • Adachi, H.1    Irie, T.2    Uekama, K.3    Manako, T.4    Yano, T.5    Saita, M.6
  • 40
    • 0027941111 scopus 로고
    • Percutaneous absorption of nafarelin acetate, an LHRH analog, through human cadaver skin and monkey skin
    • S.D. Roy, G.J. De, Percutaneous absorption of nafarelin acetate, an LHRH analog, through human cadaver skin and monkey skin, Int. J. Pharm. 110 (1994) 137-145.
    • (1994) Int. J. Pharm. , vol.110 , pp. 137-145
    • Roy, S.D.1    De, G.J.2
  • 41
    • 0028000705 scopus 로고
    • Percutaneous absorption of physiologically active peptides, ebiratide and elcatonin, in rats
    • T. Ogiso, T. Paku, M. Iwaki, T. Tanino, S. Nishioka, Percutaneous absorption of physiologically active peptides, ebiratide and elcatonin, in rats, Biol. Pharm. Bull. 17 (1994) 1094-1100.
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 1094-1100
    • Ogiso, T.1    Paku, T.2    Iwaki, M.3    Tanino, T.4    Nishioka, S.5
  • 42
    • 0022377918 scopus 로고
    • Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as poorly absorbable drugs. II. Study on the absorption promoting effect of azone
    • T. Ohshima, H. Yoshikawa, K. Takada, S. Muranishi, Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as poorly absorbable drugs. II. Study on the absorption promoting effect of azone, J. Pharmacobio-Dyn. 8 (1985) 900-905.
    • (1985) J. Pharmacobio-Dyn. , vol.8 , pp. 900-905
    • Ohshima, T.1    Yoshikawa, H.2    Takada, K.3    Muranishi, S.4
  • 43
    • 0027238062 scopus 로고
    • An improved model for studies on transdermal drug absorption in-vivo in rats
    • U. Vollmer, B. Müller, B. Wilffert, T. Peters, An improved model for studies on transdermal drug absorption in-vivo in rats, J. Pharm. Pharmacol. 45 (1993) 242-245.
    • (1993) J. Pharm. Pharmacol. , vol.45 , pp. 242-245
    • Vollmer, U.1    Müller, B.2    Wilffert, B.3    Peters, T.4
  • 44
    • 0029586116 scopus 로고
    • Effect of 2-hydroxypropyl-β-cyclodextrin on percutaneous absorption of methyl paraben
    • M. Tanaka, Y. Iwata, Y. Kouzuki, et al., Effect of 2-hydroxypropyl-β-cyclodextrin on percutaneous absorption of methyl paraben, J. Pharm. Pharmacol. 47 (1995) 897-900.
    • (1995) J. Pharm. Pharmacol. , vol.47 , pp. 897-900
    • Tanaka, M.1    Iwata, Y.2    Kouzuki, Y.3
  • 46
    • 0024539552 scopus 로고
    • Alleviation of chlorpromazine-photosensitized contact dermatitis by β-cyclodextrin derivatives and their possible mechanisms
    • T. Hoshino, K. Ishida, T. Irie, K. Uekama, T. Ono, Alleviation of chlorpromazine-photosensitized contact dermatitis by β-cyclodextrin derivatives and their possible mechanisms, J. Pharmacobio-Dyn. 12 (1989) s-70.
    • (1989) J. Pharmacobio-Dyn. , vol.12
    • Hoshino, T.1    Ishida, K.2    Irie, T.3    Uekama, K.4    Ono, T.5
  • 47
    • 0028071418 scopus 로고
    • Evaluation by laser Doppler velocimetry of the attenuation of tretinoin induced skin irritation by β-cyclodextrin complexation
    • D. Amdidouche, P. Montassier, M.C. Poelman, D. Duchêne, Evaluation by laser Doppler velocimetry of the attenuation of tretinoin induced skin irritation by β-cyclodextrin complexation, Int. J. Pharm. 111 (1994) 111-116.
    • (1994) Int. J. Pharm. , vol.111 , pp. 111-116
    • Amdidouche, D.1    Montassier, P.2    Poelman, M.C.3    Duchêne, D.4
  • 48
    • 0028342615 scopus 로고
    • Characterisation of menadione-β-cyclodextrin inclusion complex
    • B.S. Kuchekar, J.R. Vakil, Characterisation of menadione-β-cyclodextrin inclusion complex, Indian Drugs 31 (1994) 282-283.
    • (1994) Indian Drugs , vol.31 , pp. 282-283
    • Kuchekar, B.S.1    Vakil, J.R.2
  • 49
    • 0020351452 scopus 로고
    • Alleviation of prochlorperazine-induced primary irritation of skin by cyclodextrin complexation
    • K. Uekama, T. Irie, M. Sunada, M. Otagiri, Y. Arimatsu, S. Nomura, Alleviation of prochlorperazine-induced primary irritation of skin by cyclodextrin complexation, Chem. Pharm. Bull. 30 (1982) 3860-3862.
    • (1982) Chem. Pharm. Bull. , vol.30 , pp. 3860-3862
    • Uekama, K.1    Irie, T.2    Sunada, M.3    Otagiri, M.4    Arimatsu, Y.5    Nomura, S.6
  • 52
    • 0021172792 scopus 로고
    • Skin irritancy of commercially available soap and detergent bars as measured by water vapour loss
    • P.G. van der Valk, M.C. Crijns, J.P. Nater, E. Bleumink, Skin irritancy of commercially available soap and detergent bars as measured by water vapour loss, Derm. Beruf. Umwelt. 32 (1984) 87-90.
    • (1984) Derm. Beruf. Umwelt. , vol.32 , pp. 87-90
    • Van Der Valk, P.G.1    Crijns, M.C.2    Nater, J.P.3    Bleumink, E.4
  • 53
    • 0028062998 scopus 로고
    • Percutaneous absorption of benzyl acetate through rat skin in-vitro. 3. A comparison with human skin
    • A. Garnett, S.A. Hotchkiss, J. Caldwell, Percutaneous absorption of benzyl acetate through rat skin in-vitro. 3. A comparison with human skin, Food Chem. Toxicol. 32 (1994) 1061-1065.
    • (1994) Food Chem. Toxicol. , vol.32 , pp. 1061-1065
    • Garnett, A.1    Hotchkiss, S.A.2    Caldwell, J.3
  • 54
    • 0029984422 scopus 로고    scopus 로고
    • 2-Hydroxypropylated cyclodextrins as a sustained-release carrier for fragrance materials
    • M. Tanaka, H. Matsuda, H. Sumiyoshi, et al., 2-Hydroxypropylated cyclodextrins as a sustained-release carrier for fragrance materials, Chem. Pharm. Bull. 44 (1996) 416-420.
    • (1996) Chem. Pharm. Bull. , vol.44 , pp. 416-420
    • Tanaka, M.1    Matsuda, H.2    Sumiyoshi, H.3
  • 55
    • 0027241706 scopus 로고
    • Interactions between p-hydroxybenzoic acid esters and hydroxypropyl-β-cyclodextrin and thier antimicrobial effect against Candida albicans
    • S.J. Lehner, B.W. Müller, J.K. Seydel, Interactions between p-hydroxybenzoic acid esters and hydroxypropyl-β-cyclodextrin and thier antimicrobial effect against Candida albicans, Int. J. Pharm. 93 (1993) 201-208.
    • (1993) Int. J. Pharm. , vol.93 , pp. 201-208
    • Lehner, S.J.1    Müller, B.W.2    Seydel, J.K.3
  • 56
    • 0028265295 scopus 로고
    • Medicinal applications of cyclodextrins
    • J. Szejtli, Medicinal applications of cyclodextrins, Med. Res. Rev. 14 (1994) 353-386.
    • (1994) Med. Res. Rev. , vol.14 , pp. 353-386
    • Szejtli, J.1
  • 57
    • 0022616073 scopus 로고
    • Stabilization of AD-1590, a non-steroidal antiinflammatory agent, in suppository bases by β-cyclodextrin complexation
    • T. Takahashi, I. Kagami, K. Kitamura, Y. Nakanishi, Y. Imasato, Stabilization of AD-1590, a non-steroidal antiinflammatory agent, in suppository bases by β-cyclodextrin complexation, Chem. Pharm. Bull. 34 (1986) 1770-1774.
    • (1986) Chem. Pharm. Bull. , vol.34 , pp. 1770-1774
    • Takahashi, T.1    Kagami, I.2    Kitamura, K.3    Nakanishi, Y.4    Imasato, Y.5
  • 58
    • 0023639296 scopus 로고
    • Improvement of oral and rectal bioavailabilities of carmofur by methylated β-cyclodextrin complexations
    • M. Kikuchi, F. Hirayama, K. Uekama, Improvement of oral and rectal bioavailabilities of carmofur by methylated β-cyclodextrin complexations, Int. J. Pharm. 38 (1987) 191-198.
    • (1987) Int. J. Pharm. , vol.38 , pp. 191-198
    • Kikuchi, M.1    Hirayama, F.2    Uekama, K.3
  • 59
    • 0027056573 scopus 로고
    • Enhanced rectal absorption and reduced local irritation of the anti-inflammatory drug ethyl 4-biphenylylacetate in rats by complexation with water-soluble β-cyclodextrin derivatives and formulation as oleaginous suppository
    • H. Arima, T. Kondo, T. Irie, K. Uekama, Enhanced rectal absorption and reduced local irritation of the anti-inflammatory drug ethyl 4-biphenylylacetate in rats by complexation with water-soluble β-cyclodextrin derivatives and formulation as oleaginous suppository, J. Pharm. Sci. 81 (1992) 1119-1125.
    • (1992) J. Pharm. Sci. , vol.81 , pp. 1119-1125
    • Arima, H.1    Kondo, T.2    Irie, T.3    Uekama, K.4
  • 60
    • 0029871983 scopus 로고    scopus 로고
    • Combination effects of α-cyclodextrin and xanthan gum on rectal absorption and metabolism of morphine from hollow-type suppositories in rabbits
    • T. Kondo, T. Irie, K. Uekama, Combination effects of α-cyclodextrin and xanthan gum on rectal absorption and metabolism of morphine from hollow-type suppositories in rabbits, Biol. Pharm. Bull. 19 (1996) 280-286.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 280-286
    • Kondo, T.1    Irie, T.2    Uekama, K.3
  • 61
    • 0026337402 scopus 로고
    • The release of naproxen in fatty suppository bases by β-cyclodextrin complexation
    • N. Celebi, M. Iscanoglu, T. Degim, The release of naproxen in fatty suppository bases by β-cyclodextrin complexation, Pharmazie 46 (1991) 863-865.
    • (1991) Pharmazie , vol.46 , pp. 863-865
    • Celebi, N.1    Iscanoglu, M.2    Degim, T.3
  • 62
    • 0019963876 scopus 로고
    • Enhanced absorption of phenobarbital from suppositories containing phenobarbital-β-cyclodextrin inclusion complex
    • R. Iwaoku, K. Arimori, M. Nakano, K. Uekama, Enhanced absorption of phenobarbital from suppositories containing phenobarbital-β-cyclodextrin inclusion complex, Chem. Pharm. Bull. 30 (1982) 1416-1421.
    • (1982) Chem. Pharm. Bull. , vol.30 , pp. 1416-1421
    • Iwaoku, R.1    Arimori, K.2    Nakano, M.3    Uekama, K.4
  • 63
    • 0020624696 scopus 로고
    • Improvements to some pharmaceutical properties of flurbiprofen by β- and γ-cyclodextrin complexations
    • M. Otagiri, T. Imai, M. Matsuo, K. Uekama, Improvements to some pharmaceutical properties of flurbiprofen by β- and γ-cyclodextrin complexations, Acta Pharm. Suec. 20 (1983) 1-10.
    • (1983) Acta Pharm. Suec. , vol.20 , pp. 1-10
    • Otagiri, M.1    Imai, T.2    Matsuo, M.3    Uekama, K.4
  • 64
    • 0021827580 scopus 로고
    • Improvement of dissolution and suppository release characteristics of flurbiprofen by inclusion complexation with heptakis(2,6-di-O-methyl)-β-cyclodextrin
    • K. Uekama, T. Imai, T. Maeda, T. Irie, F. Hirayama, M. Otagiri, Improvement of dissolution and suppository release characteristics of flurbiprofen by inclusion complexation with heptakis(2,6-di-O-methyl)-β-cyclodextrin, J. Pharm. Sci. 74 (1985) 841-845.
    • (1985) J. Pharm. Sci. , vol.74 , pp. 841-845
    • Uekama, K.1    Imai, T.2    Maeda, T.3    Irie, T.4    Hirayama, F.5    Otagiri, M.6
  • 65
    • 0022905320 scopus 로고
    • Possible utility of β-cyclodextrin in the preparation of biphenyllactic acid suppository
    • K. Uekama, T. Maeda, H. Arima, T. Irie, F. Hirayama, Possible utility of β-cyclodextrin in the preparation of biphenyllactic acid suppository, Yakugaku Zasshi 106 (1986) 1126-1130.
    • (1986) Yakugaku Zasshi , vol.106 , pp. 1126-1130
    • Uekama, K.1    Maeda, T.2    Arima, H.3    Irie, T.4    Hirayama, F.5
  • 67
    • 0026470320 scopus 로고
    • The effects of cyclodextrins on drug release from fatty suppository bases. III. Application of cyclodextrin derivatives
    • H.W. Frijlink, S. Paiotti, A.C. Eissens, C.F. Lerk, The effects of cyclodextrins on drug release from fatty suppository bases. III. Application of cyclodextrin derivatives, Eur. J. Pharm. Biopharm. 38 (1992) 174-179.
    • (1992) Eur. J. Pharm. Biopharm. , vol.38 , pp. 174-179
    • Frijlink, H.W.1    Paiotti, S.2    Eissens, A.C.3    Lerk, C.F.4
  • 68
    • 0024820778 scopus 로고
    • Differences in the enhancing effects of water soluble β-cyclodextrins on the release of ethyl 4-biphenylyl acetate, an anti-inflammatory agent from an oleaginous suppository base
    • H. Arima, T. Irie, K. Uekama, Differences in the enhancing effects of water soluble β-cyclodextrins on the release of ethyl 4-biphenylyl acetate, an anti-inflammatory agent from an oleaginous suppository base, Int. J. Pharm. 57 (1989) 107-115.
    • (1989) Int. J. Pharm. , vol.57 , pp. 107-115
    • Arima, H.1    Irie, T.2    Uekama, K.3
  • 69
    • 0025779721 scopus 로고
    • The effects of cyclodextrins on drug release from fatty suppository bases. II. In-vivo observations
    • H.W. Frijlink, A.C. Eissens, A. Schoonen, C.F. Lerk, The effects of cyclodextrins on drug release from fatty suppository bases. II. In-vivo observations, Eur. J. Pharm. Biopharm. 37 (1991) 183-187.
    • (1991) Eur. J. Pharm. Biopharm. , vol.37 , pp. 183-187
    • Frijlink, H.W.1    Eissens, A.C.2    Schoonen, A.3    Lerk, C.F.4
  • 70
    • 0021686117 scopus 로고
    • Characteristics of drug absorption via the rectal route
    • S. Muranishi, Characteristics of drug absorption via the rectal route, Methods Find Exp. Clin. Pharmacol. 6 (1984) 763-772.
    • (1984) Methods Find Exp. Clin. Pharmacol. , vol.6 , pp. 763-772
    • Muranishi, S.1
  • 72
    • 0028875096 scopus 로고
    • Drug delivery studies in Caco2 monolayers. IV. Absorption enhancer effects of cyclodextrins
    • L. Hovgaard, H. Brondsted, Drug delivery studies in Caco2 monolayers. IV. Absorption enhancer effects of cyclodextrins, Pharm. Res. 12 (1995) 1328-1332.
    • (1995) Pharm. Res. , vol.12 , pp. 1328-1332
    • Hovgaard, L.1    Brondsted, H.2
  • 73
    • 0027067020 scopus 로고
    • Absorption enhancement of polypeptide drugs by cyclodextrins. I. Enhanced rectal absorption of insulin from hollow-type suppositories containing insulin and cyclodextrins in rabbits
    • Y. Watanabe, Y. Matsumoto, M. Seki, M. Takase, M. Matsumoto, Absorption enhancement of polypeptide drugs by cyclodextrins. I. Enhanced rectal absorption of insulin from hollow-type suppositories containing insulin and cyclodextrins in rabbits, Chem. Pharm. Bull. 40 (1992) 3042-3047.
    • (1992) Chem. Pharm. Bull. , vol.40 , pp. 3042-3047
    • Watanabe, Y.1    Matsumoto, Y.2    Seki, M.3    Takase, M.4    Matsumoto, M.5
  • 74
    • 0029780681 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of recombinant human granulocyte colony-stimulating factor (rhG-CSF) after administration of a rectal dosage vehicle
    • Y. Watanabe, M. Kiriyama, R. Ito, et al., Pharmacodynamics and pharmacokinetics of recombinant human granulocyte colony-stimulating factor (rhG-CSF) after administration of a rectal dosage vehicle, Biol. Pharm. Bull. 19 (1996) 1059-1063.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 1059-1063
    • Watanabe, Y.1    Kiriyama, M.2    Ito, R.3
  • 75
    • 0025111143 scopus 로고
    • Effect of cyclodextrins on biological membrane. I. Effect of cyclodextrins on the absorption of a non-absorbable drug from rat small intestine and rectum
    • K. Nakanishi, T. Nadai, M. Masada, K. Miyajima, Effect of cyclodextrins on biological membrane. I. Effect of cyclodextrins on the absorption of a non-absorbable drug from rat small intestine and rectum, Chem. Pharm. Bull. 38 (1990) 1684-1687.
    • (1990) Chem. Pharm. Bull. , vol.38 , pp. 1684-1687
    • Nakanishi, K.1    Nadai, T.2    Masada, M.3    Miyajima, K.4
  • 76
    • 0026022439 scopus 로고
    • Effect of inclusion complexation of decanoic acid with α-cyclodextrin on rectal absorption of cefmetazole sodium suppository in rabbits
    • H. Yanagi, N. Ishikura, H. Kenmotsu, et al., Effect of inclusion complexation of decanoic acid with α-cyclodextrin on rectal absorption of cefmetazole sodium suppository in rabbits, Yakugaku Zasshi 111 (1991) 65-69.
    • (1991) Yakugaku Zasshi , vol.111 , pp. 65-69
    • Yanagi, H.1    Ishikura, N.2    Kenmotsu, H.3
  • 77
    • 0021984043 scopus 로고
    • Selective transfer of 1-hexylcarbamoyl-5-fluorouracil into lymphatics by combination of β-cyclodextrin polymer complexation and absorption promotor in the rat
    • Y. Kaji, K. Uekama, H. Yoshikawa, K. Takada, S. Muranishi, Selective transfer of 1-hexylcarbamoyl-5-fluorouracil into lymphatics by combination of β-cyclodextrin polymer complexation and absorption promotor in the rat, Int. J. Pharm. 24 (1985) 79-89.
    • (1985) Int. J. Pharm. , vol.24 , pp. 79-89
    • Kaji, Y.1    Uekama, K.2    Yoshikawa, H.3    Takada, K.4    Muranishi, S.5
  • 78
    • 0029556984 scopus 로고
    • Modification of rectal absorption of morphine from hollow-type suppositories with a combination of α-cyclodextrin and viscosity-enhancing polysaccharide
    • K. Uekama, T. Kondo, K. Nakamura, et al., Modification of rectal absorption of morphine from hollow-type suppositories with a combination of α-cyclodextrin and viscosity-enhancing polysaccharide, J. Pharm. Sci. 84 (1995) 15-20.
    • (1995) J. Pharm. Sci. , vol.84 , pp. 15-20
    • Uekama, K.1    Kondo, T.2    Nakamura, K.3
  • 79
    • 0024989124 scopus 로고
    • Effect of β-cyclodextrin on the in-vitro permeation rate and in-vivo rectal absorption of acetaminophen hydrogel preparations
    • S.Y. Lin, J.C. Yang, Effect of β-cyclodextrin on the in-vitro permeation rate and in-vivo rectal absorption of acetaminophen hydrogel preparations, Pharm. Acta Helv. 65 (1990) 262-268.
    • (1990) Pharm. Acta Helv. , vol.65 , pp. 262-268
    • Lin, S.Y.1    Yang, J.C.2
  • 80
    • 0026571595 scopus 로고
    • Use of water-soluble β-cyclodextrin derivatives as carriers of anti-inflammatory drug biphenylylacetic acid in rectal delivery
    • H. Arima, T. Kondo, T. Irie, et al., Use of water-soluble β-cyclodextrin derivatives as carriers of anti-inflammatory drug biphenylylacetic acid in rectal delivery, Yakugaku Zasshi 112 (1992) 65-72.
    • (1992) Yakugaku Zasshi , vol.112 , pp. 65-72
    • Arima, H.1    Kondo, T.2    Irie, T.3
  • 81
    • 0025609696 scopus 로고
    • Piroxicam-β-cyclodextrin in the treatment of dysmenorrhoea
    • S. Costa, G. Zinelli, L. Bufalino, Piroxicam-β-cyclodextrin in the treatment of dysmenorrhoea, Drug Invest. 4 (1990) 73-78.
    • (1990) Drug Invest. , vol.4 , pp. 73-78
    • Costa, S.1    Zinelli, G.2    Bufalino, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.