Combination effects of α-cyclodextrin and xanthan gum on rectal absorption and metabolism of morphine from hollow-type suppositories in rabbits

Biological and Pharmaceutical Bulletin

Volumn 19, Issue 2, 1996, Pages 280-286

  Kondo, Takashi ^a   Irie, Tetsumi ^a   Uekama, Kaneto ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

glucuronidation; morphine; rectal absorption; transepithelial conductance; xanthan gum; cyclodextrin

Indexed keywords

ALPHA CYCLODEXTRIN; GLUCOSYLTRANSFERASE; MORPHINE; NALOXONE; XANTHAN;

ANALGESIA; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER ADJUVANT THERAPY; CANCER PAIN; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ADMINISTRATION; DRUG BIOAVAILABILITY; DRUG METABOLISM; DRUG PENETRATION; INTESTINE ABSORPTION; MALE; NONHUMAN; RABBIT; RECTAL DRUG ADMINISTRATION; RECTUM MUCOSA; SUPPOSITORY;

EID: 0029871983     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.19.280     Document Type: Article

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