Effect of NGF treatment on outcome measures in a rat model of middle cerebral artery occlusion

Journal of Neuroscience Research

Volumn 55, Issue 3, 1999, Pages 357-369

  Kent, T A ^a   Quast, M ^b   Taglialatela, G ^a   Rea, C ^a   Wei, J ^b   Tao, Z ^a   Perez Polo, J Regino ^a,c  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c NONE   (United States)

Author keywords

Glutathione; Magnetic resonance imaging; Middle cerebral artery occlusion; Nerve growth factor; Nuclear magnetic resonance; Stroke

Indexed keywords

GLUTATHIONE; NERVE GROWTH FACTOR; PHOSPHATE; PHOSPHORUS 31;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENERGY METABOLISM; GROWTH REGULATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NERVE GROWTH; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; PREDICTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CAUDATE NUCLEUS; CEREBRAL ARTERIES; DNA FRAGMENTATION; HIPPOCAMPUS; MAGNETIC RESONANCE IMAGING; MALE; NERVE GROWTH FACTORS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033081976     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990201)55:3<357::AID-JNR11>3.0.CO;2-W     Document Type: Article

References (65)

1. Ayer-Lelievre C, Olson L., Ebendal T, Seiger A, Persson H. 1988. Expression of the β-nerve growth factor gene in hippocampal neurons. Science 240:1339-1341.
2. Barren GL, Bartlett PF. 1994. The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development. Proc Natl Acad Sci USA 91:6501-6505.
3. Buchan AM, Williams L, Bruederlin B. 1990. Nerve growth factor: Pretreatment ameliorates ischemic hippocampal neuronal injury. Stroke 21:177.
4. Charriaut-Marlangue C, Margaill I, Represa A, Popovici T, Plotkine M, Ben-Ari Y. 1996. Apoptosis and necrosis after reversible focal ischemia: An in situ DNA fragmentation analysis. J Cerebral Blood Flow Metab 16:186-194.
5. Chen J, Jin K, Chen M, Pei W, Kawaguchi K, Greenberg DA, Simon RP. 1997. Early detection of DNA strand breaks in the brain after transient focal ischemia: Implications for the role of DNA damage in apoptosis and neuronal cell death. J Neurochem 69:232-245.
6. Choi D. 1996. Ischemia-induced neuronal apoptosis. Curr Opin Neurobiol 6:667-672.
7. Commelli MC, Guidolin D, Seren MS, Zanoni R, Canella R, Ruhini R, Manev H. 1993. Time course, localization and pharmacological modulation of immediate early inducible genes, brain-derived neurotrophic factor and trkB messenger RNAs in the rat brain following photochemical stroke. Neuroscience 55:473-490.
8. Frade JM, Rodriguez-Tabar A, Barde Y-A. 1996. Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383:166-168.
9. Gall C, Murray K, Issackson PJ. 1991. Kainic acid-induced seizures stimulate increased expression of nerve growth factor in the rat hippocampus. Mol Brain Res 6:275-287.
10. Guillardon F, Lenz C, Waschke KF, Krajewski S, Reed JC, Zimmermann M, Kuschinsky W. 1996. Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats. Mol Brain Res 40:254-260.
11. Griffith OW. 1980. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinyl-pyridine. Anal Biochem 106:207-212.
12. Hara A, Yoshimi N, Hirose Y, Ino N, Tanaka T, Mori H. 1995. DNA fragmentation in granular cells of human cerebellum following global ischemia. Brain Res 697:247-250.
13. Hashimoto Y, Kawatsura H, Shiga Y, Furukawa S, Shigeno T. 1992. Significance of nerve growth factor content levels after transient forebrain ischemia in gerbils. Neurosci Lett 139:45-46.
14. Hefti, F., Knusel, B. and Lapchak PA. 1993. Protective effects of nerve growth factor and brain-derived neurotrophic factor on basal forebrain cholinergic neurons in adult rats with partial fimbrial transections. Prog Brain Res 98:257-263.
15. Hill IE, MacManus JP, Rasquinha I, Tuor UI. 1995. DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat. Brain Res 676:398-403.
16. Huang NC, Wei J, Quast MJ. 1996. A comparison of the early development of ischemic brain damage in normoglycemic and hyperglycemic rats using magnetic resonance imaging. Exp Brain Res 109:33-42.
17. Islam N, Aftabuddin M, Moriwaki A, Hori Y. 1995. Detection of DNA damage induced by apoptosis in the rat brain following incomplete ischemia. Neurosci Lett 188:159-162.
18. Iwai T, Hara A, Niva M, Nozaki M, Uematsu T, Sakai N, Yamada H. 1995. Temporal profile of nuclear DNA fragmentation in situ in gerbil hippocampus following transient forebrain ischemia. Brain Res 671:305-308.
19. Jackson GR, Werrbach-Perez K, Ezell EL, Post JFM, Perez-Polo JR. 1992. Nerve growth factor effects on pyridine nucleotides after oxidant injury of rat pheochromocytoma cells. Brain Res 592: 239-248.
20. Jackson GR, Sampath D, Werrbach-Perez K, Perez-Polo JR. 1994a. Effects of nerve growth factor on catalase and glutathione peroxidase in a hydrogen-resistant pheochromocytoma subclone. Brain Res 634:69-76.
21. Jackson GR, Werrbach-Perez K, Pan Z, Sampath D, Perez-Polo JR. 1994b. Neurotrophin regulation of energy homeostasis in the central nervous system. Dev Neurosci 16:285-290.
22. Kinuta Y, Kikuchi H, Ishikawa M, Kimura M, Itokawwa Y. 1989. Lipid peroxidation in focal cerebral ischemia. J Neurosurg 71: 421-429.
23. Kokaia Z, Zhao Q, Kokaia M, Elmer E, Metsis M, Smith M-L, Siesjo K Lindvall O. 1995. Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damage. Exp Neurol 136: 73-88.
24. Kondo T, Reaume AG, Haung TT, Carlson E, Murakami K, Chen SF, Hoffman EK, Scott RW, Epstein CJ, Chan PH. 1997. Reduction of CuZn-superoxide disniutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J Neurosci 17:4180-4189.
25. Korsching S, Auburger G, Heumann R, Scott J, Thoenen H. 1985. Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J 4:1389-1393.
26. LeBihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. 1986. MR imaging of intravoxel incoherent motions: Application to diffusion and perfusion in neurologic disorders. Radiology 161:401-407.
27. Lee T-H, Kogure AK, Itoyama KH. 1995. Expressions of nerve growth factor and p75 low affinity receptor after transient forebrain ischemia in gerbil hippocampal CA1 neurons. J Neurosci Res 41:684-695.
28. Levi-Montalcini R, Skaper SD, Daltoso R, Petrelli L, Leon A. 1996. Nerve growth factor - from neurotrophin to neurokine. Trends Neurosci 19:514-520.
29. Li Y, Chopp M, Jiang N, Zhang ZG, Zaloga C. 1995. Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats. Stroke 26:1252-1257.
30. Lindvall O, Ernfors P, Bengzon J, Kokaia Z, Smith M-L, Siesjo BK, Persson H. 1992. Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc Natl Acad Sci USA 89:648-652.
31. Lipton SA. 1996. Similarity of neuronal cell injury and death in AIDS dementia and focal cerebral ischemia; potential treatment with NMDA open-channel blockers and nitric oxide related species. Br Path 6:507-517.
32. Longa EZ, Weinstein PR, Carlson S, Cummins R. 1989. Reversible middle cerebral artery occlusion without craniotomy in rats. Stroke 20:84-91.
33. Lorez H, Keller F, Ruess G, Otten U. 1989. Nerve growth factor increases in adult rat brain after hypoxic injury. Neurosci Lett 98:339-344.
34. Marx JL. 1986. Nerve growth factor acts in brain. Science 232:1341-1342.
35. Moseley ME, Cohen Y, Mintorovitch J, Chileuitt L, Shimizu H, Kucharczyk J Wendland MF, Weinstein PR. 1990. Early detection of regional cerebral ischemia in cats: comparison of diffusion-and T2-weighted MRI and spectroscopy. Magn Reson Med 14:330-346.
36. Nagasawa H, Kogure K. 1989. Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion. Stroke 20:1037-1043.
37. Nishio T, Furukawa S, Akiguchi I, Oka N, Ohnishi K, Tomimoto H, Nakamura S, Kimura J. 1994. Cellular localization of nerve growth factor-like immunoreactivity in adult rat brain: quantitative and immunohistochemical study. Neuroscience 60:67-84.
38. Oldridge RJ, Conneley A, Lohman JAB. 1986. Image-selected in vivo spectroscopy (ISIS) A new technique for spatially selective NMR spectroscopy. J Magn Reson 66:283-294.
39. Pan Z, Perez-Polo R. 1993. Role of nerve growth factor in oxidant homeostasis: Glutathione metabolism. J Neurochem 61:1713-1721.
40. Pan Z, Perez-Polo JR. 1996a. Increased uptake of L-cysteine and L-cystine by nerve growth factor in rat pheochromocytoma cells. Brain Res 740:21-26.
41. Pan Z, Perez-Polo R. 1996b. Regulation of gamma-glutamylcysteine synthetase activity by nerve growth factor. Int J Dev Neurosci 14:559-566.
42. Pan Z, Sampath D, Jackson G, Werrbach-Perez K, Perez-Polo R. 1997. Nerve growth factor and oxidative stress in the nervous system. In: Filogamo et al., editors. Brain plasticity. New York: Plenum Press. p 173-193.
43. Petito CK, Torres-Munoz J, Roberts B, Olate JP, Mowak TS Jr, Pulsinelli WA. 1997. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat. J Cereb Blood Flow Metab 17:967-976.
44. Quast MJ, Huang N, Hillman GR, Kent TA. 1993. The evolution of acute stroke recorded by multimodal magnetic resonance imaging. Magn Reson Imaging 11:465-471.
45. Quast MJ, Wei J, Huang NC. 1995. Nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester decreases ischemic damage in reversible focal ischemia in hyperglycemic rats. Brain Res 677:204-212.
46. Rabizadeh S, Oh J, Zhong L-T, Yang J, Bitler CM, Butcher LL, Bredesen DE. 1993. Induction of apoptosis by the low-affinity NGF receptor. Science 261:345-348.
47. Raff M. 1992. Social controls on cell survival and cell death. Nature 356:397-401.
48. Ratan RR, Murphy TH, Baraban JM. 1994. Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J Neurosci 14:4385-4392.
49. Rossner S, Yu J, Pizzo D, Werrbach-Perez K, Schliebs R, Big V and Perez-Polo JR. 1996. Effects of intraventricular transplantation of NGF-secreting cells on cholinergic basal forebrain neurons after partial immunolesion. J Neurosci Res 45:40-56.
50. Schmidt-Kastner R, Riss H, Hakim AM. 1997. Subtle neuronal death in striatum after short forebrain ischemia in rats detected by in situ end labeling for DNA damage. Stroke 28:169-170.
51. Shigeno T, Mima T, Takakura K, Graham DI, Kato G, Hashimoto Y, Furukawa S. 1991. Amelioration of delayed neuronal death in the hippocampus by nerve growth factor. J Neurosci 11:2914-2919.
52. Shozuhara H, Onodera H, Katoh-Semba R, Kato K, Yamasaki Y, Kogure K. 1992. Temporal profiles of nerve growth factor β-subunit level in rat brain regions after transient ischemia. J Neurochem 59:175-180.
53. Sommer C, Gass P, Kiessling M. 1995. Selective c-Jun expression in CA1 neurons of the gerbil hippocampus during and after acquisition of an ischemia-tolerant state. Br Path 5:135-144.
54. Springer JE. 1988. Nerve growth factor receptors in the central nervous system. Exp Neurol 102:354-365.
55. Taglialatela G, Gegg M, Perez-Polo JR, Williams L, Rose GM. 1996a. Evidence for DNA fragmentation in the CNS of aged Fischer-344 rats. NeuroReport 7:977-980.
56. trk does not abolish nerve growth factor rescue of apoptotic PC12 cells and enables brain-derived neurotrophic factor to promote cell survival. J Neurochem 66:1826-1835.
57. Taglialatela G, Robinson R, Gegg M, Perez-Polo JR. 1997. Nerve growth factor, central nervous system apoptosis and adrenocortical activity in aged Fischer-344/Brown Norway F1 hybrid rats. Brain Res Bull 43:229-233.
58. Takeda A, Onodera H, Sugimoto A, Kogure K, Obinata M, Shibahara S. 1993. Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient fore-brain ischemia. Neuroscience 55:23-31.
59. Tietze F. 1969. Enzymic method for quantitative determination of nanogram amounts for total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 27:502-522.
60. Tong L, Toliver-Kinsky T, Taglialatela G, Werrbach-Perez K, Wood T, Perez-Polo JR. 1998. Signal transduction in neuronal death. J Neurochem 71:447-459.
61. Van der Zee CEEM, Ross GR, Riopelle RJ. 1996. Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice. Science 274:1729-1732.
62. Whittemore SR, Friedman PL, Larhammer D, Persson H, Gonzalez-Carvajal M, Holets VR. 1988. Rat β-nerve growth factor sequence and site of synthesis in the adult hippocampus. J Neurosci Res 20:403-410.
63. Wörtwein G, Yu J, Toliver-Kinsky T, Perez-Polo JR. 1998. Responses of young and aged rat CNS to partial cholinergic immunolesions and NGF treatment. J Neurosci Res 52:322-333.
64. Wyllie AH, Kerr JFTR, Currie AR. 1980. Cell death: the significance of apoptosis. Int Rev Cytol 68:251-305.
65. Yu J, Wiley RG, Perez-Polo JR. 1996. Altered NGF protein levels in different brain areas after immunolesion. J Neurosci Res 43:213-223.