Dendritic cells, T- and B-lymphocytes and macrophages in squamous cell carcinomas of the supraglottic and glottic region: Localization and correlation to prognosis;Dendritische zellen, T-und B-lymphozyten und makro-phagen im supraglottischen und glottischen platten-epithelkarzinom. Lokalisation und korrelation zur prognose der erkrankung

HNO

Volumn 47, Issue 5, 1999, Pages 466-471

  Jecker, P ^a   Vogl, K ^a   Tietze, L ^a   Westhofen, M ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Mucosal immune system; Prognosis; Squamous cell carcinoma; Tumor defense

Indexed keywords

ANTIBODY; ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN;

ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; DENDRITIC CELL; FEMALE; GLOTTIS; HUMAN; IMMUNE SYSTEM; IMMUNOHISTOLOGY; MACROPHAGE; MALE; PROGNOSIS; SQUAMOUS CELL CARCINOMA; T LYMPHOCYTE;

ADULT; AGED; B-LYMPHOCYTE SUBSETS; CARCINOMA, SQUAMOUS CELL; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; FEMALE; HUMANS; HYPOPHARYNGEAL NEOPLASMS; HYPOPHARYNX; LARYNGEAL NEOPLASMS; LARYNX; MALE; MIDDLE AGED; PROGNOSIS; SURVIVAL RATE; T-LYMPHOCYTE SUBSETS;

EID: 0033066513     PISSN: 00176192     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001060050406     Document Type: Article

References (22)

1. Abbas AK, Lichtman AH, Pober JS (1994) Cellular and molecular immunology. Saunders, Philadelphia
2. rd edn. Springer, Berlin Heidelberg New York
3. Brockmühl U (1998) Bedeutung der Analyse genetischer Alterationen bei Kopf-Hals-Karzinomen. HNO 46:74-83
4. Brandtzaeg P, Jahnsen FL, Farstad IN (1996) Immune functions and immunopathology of the mucosa of the upper respiratory pathways. Acta Otolaryngol (Stockh) 116:149-159
5. Cella M, Sallusto F, Lanzavecchia A (1997) Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 9:10-16
6. Gabrilovich D, Nadaf S, Corak J, Berzofsky YA, Carbone DP (1996) Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice, are effective antigen carriers in the therapy of established tumors. Cell Immunol 170:111-119
7. Gallo O, Asparrella-Libonati G, Gallina E, Fini-Storchi O, Giannini A, Urso C, Bondi R (1991) Langerhans cells related to prognosis in patients with laryngeal carcinoma. Arch Otolaryngol Head Neck Surg 117:1007-1010
8. Ganzer U (1991) Die Prognose des Kehlkopfkarzinoms seit 1960. Laryngo Rhino Otol 69:1-5
9. Goldman SA, Baker E, Weyant RJ, Clarke MR, Myers JN, Lotze MT (1998) Peritumoral CD1 a-positive dendritic cells are associated with improved survival in patients with tongue carcinoma. Arch Otolaryngol Head Neck Surg 124:641-646
10. Golusinski W, Szmeja Z, Oloffson J, Biczysko W, Krygier-Stojalzowska A, Majewski P (1998) Retrospektive Analyse ausgewählter Tumormarker (p53, PCNA, Ki67, DNA-Ploidie) und der Ultrastruktur bei Kranken mit Larynxkarzinom. HNO 46:233-240
11. Gong J, Chen D, Kashiwaba M, Kufe D (1997) Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells. Gene Ther 3:558-561
12. Hart DNJ (1997) Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 90:3245-3287
13. Ishigami S, Aikou T, Natsugoe S, Hokita S, Iwashige H, Tokushige M, Sonoda S (1998) Prognostic value of HLA-DR expression and dendritic cell infiltration in gastric cancer. Oncology 55:65-69
14. Jecker P, Beulecke A, Dressendörfer l, Pabst R, Westermann J (1997) Long-term oral application of 5-bromo-2-deoxyuridine does not reliably label proliferating immune cells in the LEW rat. J Histochem Cytochem 45:393-401
15. Jecker P, Ptok M, Pabst R,Westermann J (1996) Distribution of immunocompetent cells in various areas in the normal laryngeal mucosa of the rat. Eur Arch Otorhinolaryngol 253:142-146
16. Jecker P, Ptok M, Westermann J, Pabst R (1996) Age dependency of the composition of immunocompetent cells and the expression of adhesion molecules in the rat laryngeal mucosa. Laryngoscope 106:733-738
17. Kurtulmaz SY, Erkal HS, Serin M, Elhan A, Cakmak A (1997) Squamous cell carcinomas of the head and neck: descriptive analysis of 1293 cases. J Laryngol Otol 111:531 -535
18. Nestle FO, Alijagic S, Gilliet M et al. (1998) Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat Med 4:328-332
19. Olsen KD, Rohe DE, Perry WC, Keith RL (1995) Quality of life after surgical treatment of cancer of the larynx. Ann Otol Rhinol Laryngol 104:763-769
20. Schuler G, Romani N (1997) Generation of mature dendritic cells from human blood. Adv Exp Med Biol 417:7-13
21. Schuler G, Steinman RM (1997) Dendritic cells as adjuvants for immune-mediated resistance to tumors. J Exp Med 186:1183-1187
22. Westermann J, Pabst R (1990) Lymphocyte subsets in the blood: a diagnostic window on the lymphoid system? Immunol Today 11:406-410