Bcl-2 expression regulates cell sensitivity to S100β-mediated apoptosis

Molecular Brain Research

Volumn 70, Issue 1, 1999, Pages 167-176

  Wang, Shu ^a   Rosengren, Lars E ^a   Franlund, Maria ^a   Hamberger, Anders ^a   Haglid, Kenneth G ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Apoptosis; Bcl 2; Neurons; S100

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; DNA FRAGMENT; PROTEIN BCL 2; PROTEIN S 100; RETINOIC ACID;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; DOWN SYNDROME; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NERVE CELL CULTURE; PRIORITY JOURNAL; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALZHEIMER DISEASE; APOPTOSIS; CALCIUM-BINDING PROTEINS; CULTURE MEDIA, SERUM-FREE; DOWN SYNDROME; GENE EXPRESSION REGULATION; GENES, BCL-2; HUMANS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-BCL-2; S100 PROTEINS;

EID: 0033064119     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00145-X     Document Type: Article

References (44)

1. Barger S.W., Van Eldik L.J., Mattson M.P. S100β protects hippocampal neurons from damage induced by glucose deprivation. Brain Res. 677:1995;167-170.
2. Barger S.W., Wolchok S.R., Van Eldik L.J. Disulfide-liked S100β dimers and signal transduction. Biochim. Biophys. Acta. 1160:1992;105-112.
3. Batistatou A., Merry D.E., Korsmeyer S.J., Greene L.A. Bcl-2 affects survival but not neuronal differentiation of PC12 cells. J. Neurosci. 13:1993;4422-4428.
4. Baudier J., Labourdette G., Gerard D. Rat brain S100β protein: purification, characterization and ion binding properties. A comparison with bovine S100β protein. J. Neurochem. 44:1985;76-84.
5. Behl C., Hovey L., Krajewski S., Schubert D., Reed J.C. BCL-2 prevents killing of neuronal cells by glutamate but not by amyloid beta protein. Biochem. Biophys. Res. Commun. 197:1993;949-956.
6. Bhattacharyya A., Oppenheim R.W., Prevette D., Moore B.W., Brackenbury R., Ratner N. S100 is present in developing chicken neurons and schwann cells and promotes motor neuron survival in vivo. J. Neurobiol. 23:1992;451-466.
7. Bonfati L., Strettori E., Chierzi S., Cenni M.C., Liu X.-H., Martinou J.-C., Maffei L., Rabacchi S.A. Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2. J. Neurosci. 16:1996;4186-4194.
8. Cotman C.W., Anderson A.J. A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Mol. Neurobiol. 10:1995;19-45.
9. Dubois-Dauphin M., Frankowski H., Tsujimoto Y., Huarte J., Martinou J.C. Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axomy-induced cell death. Proc. Natl. Acad. Sci. USA. 91:1994;3309-3313.
10. Fano G., Mariggio M.A., Angelella P., Nicoletti I., Antonica A., Fulle S., Calissano P. The S-100 protein causes an increase of intracellular calcium and death of PC12 cells. Neuroscience. 53:1993;919-925.
11. Farlie P.G., Drigen R., Rees S.M., Kannourakis G., Bernard O. bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc. Natl. Acad. Sci. USA. 92:1995;4397-4401.
12. Frade J.M., Rodriguez-Tebar A., Barde Y.-A. Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature. 383:1996;166-168.
13. Frade J.M., Barde Y.-A. Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron. 20:1998;35-41.
14. Fulle S., Mariggio M.A., Bella S., Nicolettti I., Fano G. Nerve growth factor inhibits apoptosis induced by S100 binding in neuronal PC12 cells. Neuroscience. 76:1997;159-166.
15. Garicia I., Martinou I., Tsujimoto Y., Martinou J.C. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science. 258:1992;302-304.
16. Griffin W.S.T., Stanley L.C., Ling C., White L., MacLeod V., Perrot L.J., White C.L., Araoz C. Brain interleukin 1 and S100 immunoreactivity are elevated in Down syndrome and Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 86:1989;7611-7615.
17. Hu J., Van Eldik L.J. S100β induces apoptotic cell death in cultured astrocytes via a nitric oxide-dependent pathway. Biochim. Biophys. Acta. 1313:1996;239-245.
18. Hu J., Ferreira A., Van Eldik L.J. S100β induces neuronal cell death through nitric oxide release from astrocytes. J. Neurochem. 69:1997;2294-2301.
19. Haglid K.G., Stavrou D., Rönnbäck L., Carlsson C.A., Weidenbach W. The S-100 protein in water-soluble and pentanol extractable form in normal human brain and tumours of the human nervous system. A quantitative study. J. Neurol. Sci. 20:1973;103-111.
20. He H., Lam M., McCormick T.S., Distelhorst C.W. Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2. J. Cell Biol. 138:1997;1219-1228.
21. 2+ mobilization. Am. J. Physiol. 275(3 Pt 1):1998;C832-839.
22. Jorgensen O.S., Brooksbank B.W.L., Balazs R. Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer's disease. J. Neurol. Sci. 98:1990;63-79.
23. Kessler J.A., Ludiam W.H., Freidin M.M., Hall D.H., Machaelson M.D., Spray D.C., Dougherty M., Batter D.K. Cytokine-induced programmed death of cultured sympathetic neurons. Neuron. 11:1993;1123-1132.
24. Mah S., Zhong L.T., Liu Y., Roghani A., Edwards R.H., Bredesen D.E. The protooncogene bcl-2 inhibits apoptosis in PC12 cells. J. Neurochem. 60:1993;1183-1186.
25. Mariggio M.A., Fulle S., Calissano P., Nicoletti I., Fano G. The brain protein S-100ab induces apoptosis in PC12 cells. Neuroscience. 60:1994;29-35.
26. Marshak D.R. S100β as a neurotrophic factor. Prog. Brain Res. 86:1990;169-181.
27. Martinou J-C., Dubois-Dauphin M., Staple J.K., Rodriguez I., Frankowski H., Missotten M., Albertinin P., Talabot D., Catsicas S., Pietra C., Huarte J. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron. 13:1994;1017-1030.
28. Merry D.E., Veis D.J., Hickey W.F., Korsmeyer S.J. bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development. 120:1994;301-311.
29. Moore B.W. A soluble protein characteristic of the nervous system. Biochem. Biophys. Res. Commun. 19:1965;739-744.
30. Murphy A.N., Bredesen D.E., Cortopassi G., Wang E., Fiskum G. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc. Natl. Acad. Sci. USA. 93:1996;9893-9898.
31. Paradis E., Douillard H., Koutroumanis M., Goodyer C., LeBlanc A. Amyloid b peptide of Alzheimer's disease downregulates Bcl-2 and upregulates Bax expression in human neurons. J. Neurosci. 16:1996;7523-7539.
32. Pleasure S.J., Page C., Lee V.M.Y. Pure, postmitotic, polarized human neurons derived from Ntera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J. Neurosci. 12:1992;1802-1815.
33. Pleasure S.J., Lee V.M.Y. Ntera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell. J. Neurosci. Res. 35:1993;585-602.
34. Reed J.C. Double identity for proteins of the Bcl-2 family. Nature. 387:1997;773-776.
35. Reed J.C., Meister L., Tanaka S., Cuddy M., Yum S., Geyer C., Pleasure D. Differential expression of bcl-2 protoonocogene in neuroblastoma and other human tumor cell lines of neural origin. Cancer Res. 51:1991;6529-6538.
36. J. Sambrook, E.F. Fritsch, T. Maniatis, Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Press, New York, 1989.
37. Sato N., Hotta K., Waguri S., Nitatori T., Tohyama K., Tsujimoto Y., Uchiyama Y. Neuronal differentiation of PC12 cells as a result of prevention of cell death by bcl-2. J. Neurobiol. 25:1994;1227-1234.
38. Satou T., Cummings B.J., Cotman C.W. Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity. Brain Res. 697:1995;35-43.
39. Sawa A., Oyama F., Cairns N.J., Amano N., Matsushita M. Aberrant expression of bcl-2 gene family in Down's syndrome brains. Mol. Brain. Res. 48:1997;53-59.
40. Sheng J.G., Mrak R.E., Griffin W.S.T. S100 protein expression in Alzheimer's disease: Potential role in the pathogenesis of neuritic plaues. J. Neurosci. Res. 39:1994;398-404.
41. Su J.H., Satou T., Anderson A.J., Cotman C.W. Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease. Neuroreport. 7:1996;437-440.
42. Van Eldik L.J., Griffin W.S.T. S100β expression in Alzheimer's disease: relation to neuropathology in brain regions. Biochim. Biophys. Acta. 1223:1994;398-403.
43. Yokoyama Y., Ozawa S., Seyama Y., Namiki H., Hayashi Y., Kali K., Shirama K., Shioda M., Kano K. Enhancement of apoptosis in developing chick neural retina cells by basic fibroblast growth factor. J. Neurochem. 68:1997;2212-2215.
44. Zhong L.T., Sarafian T., Kane D.J., Charles A.C., Mah S.P., Edwards R.H., Bredesen D.E. Bcl-2 inhibits death of central neural cell induced by multiple agents. Proc. Natl. Acad. Sci. USA. 90:1993;4533-4537.