Apoptosis inhibition and ornithine decarboxylase superinduction as early epigenetic events in morphological transformation of Syrian hamster embryo cells exposed to 2-methoxyacetaldehyde, a metabolite of 2-methoxyethanol

Toxicology Letters

Volumn 105, Issue 2, 1999, Pages 163-175

  Dhalluin, S ^a   Elias, Z ^b   Poirot, O ^b   Gate, L ^a   Pages, N ^a   Tapiero, H ^a   Vasseur, P ^c   Nguyen Ba, G ^a  

^a UNIV PARIS SUD   (France)

^b INSTITUT NATIONAL DE RECHERCHE ET DE SÉCURITÉ   (France)

^c Environment Science Centre   (France)

Author keywords

Apoptosis inhibition; Cell transformation; Glycol ether; ODC superinduction

Indexed keywords

2 METHOXYETHANOL; DRUG METABOLITE; METHOXYACETIC ACID; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENIC ACTIVITY; CELL CULTURE; CELL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; EMBRYO CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; SYRIAN HAMSTER; WESTERN BLOTTING;

ACETALDEHYDE; ANIMALS; APOPTOSIS; BCL-X PROTEIN; CARCINOGENICITY TESTS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CRICETINAE; DNA FRAGMENTATION; EMBRYO; ENZYME INDUCTION; ETHYLENE GLYCOLS; FEMALE; MESOCRICETUS; ORNITHINE DECARBOXYLASE; PROTO-ONCOGENE PROTEINS C-BCL-2; TERATOGENS; TETRADECANOYLPHORBOL ACETATE; XENOBIOTICS;

EID: 0033063435     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00396-8     Document Type: Article

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