Comparative effects of clofibrate and methyl clofenapate on morphological transformation and intercellular communication of Syrian hamster embryo cells

Carcinogenesis

Volumn 18, Issue 4, 1997, Pages 701-706

  Cruciani, Véronique ^a   Rast, Claudine ^a   Durand, Marie José ^a   Nguyen Ba, Giao ^b   Vasseur, Paule ^a  

^a Ctr des Sciences de l'Environnement   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; CLOFIBRATE; LUCIFER YELLOW; METHYLCLOFENAPATE; PEROXISOME PROLIFERATOR; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL COMMUNICATION; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG POTENCY; DRUG POTENTIATION; EMBRYO; EMBRYO CELL; GAP JUNCTION; LIVER CARCINOGENESIS; NONHUMAN; PRIORITY JOURNAL; SYRIAN HAMSTER;

ANIMALS; CELL COMMUNICATION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CLOFENAPATE; CLOFIBRATE; CRICETINAE; GAP JUNCTIONS; MESOCRICETUS;

EID: 0031417555     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.4.701     Document Type: Article

References (51)

1. Hess, R., Staubli, W. and Riess, W. (1965) Nature of the hepatomegalic effect produced by ethyl-chlorophenoxy-isobutyrate in the rat. Nature, 208, 856-858.
2. Reddy, J.K. and Lalwani, N.D. (1983) Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. CRC Crit. Rev. Toxicol., 12, 1-58.
3. Reddy, J.K., Azamoff, D.L. and Hignite, C.E. (1980) Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature, 283, 397-398.
4. Rao, M.S. and Reddy, J.K. (1987) Peroxisome proliferation and hepatocarcinogenesis. Carcinogenesis, 8, 631-636.
5. Stott, W.T. (1988) Chemically induced proliferation of peroxisomes: implications for risk assessment. Regulat. Toxicol. Pharmacol., 8, 125-159.
6. Reddy, J.K. (1990) Carcinogenicity of peroxisome proliferators: evaluation and mechanisms. Biochem. Soc. Trans., 18, 92-94.
7. Reddy, J.K., Lalwani, N.D., Reddy, M.K. and Qureshi, S.A. (1982) Excessive accumulation of autofluorescent lipofuscin in the liver during hepatocarcinogenesis by methyl clofenapate and other hypolipidemic peroxisome proliferators. Cancer Res., 42, 259-266.
8. Cattley, R.C, Marsman, D.S. and Popp, J.A. (1991) Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator Wy-14,643 in rat liver. Carcinogenesis, 12, 469-473.
9. Issemann, I. and Green, S. (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature, 347, 645-650.
10. Aperlo, C., Pognonec, P., Saladin, R., Auwerx, J. and Boulukos, K.E. (1995) cDNA cloning and characterization of the transcriptional activities of the hamster peroxisome proliferator-activated receptor haPPARγ. Gene, 162, 297-302.
11. Svoboda, D.J. and Azarnoff, D.L. (1979) Tumors in male rats fed ethyl chlorophenoxyisobutyrate, a hypolipidemic drug. Cancer Res., 39, 3419-3428.
12. Berwald, Y. and Sachs, L. (1963) In vitro cell transformation with chemical carcinogens. Nature, 200, 1182-1184.
13. Di Paolo, J.A., Donovan, P.J. and Nelson, R.L. (1969) Quantitative studies of in vitro transformation by chemical carcinogens. J. Natl Cancer Inst., 42, 867-876.
14. Di Paolo, J.A., Nelson, R.L. and Donovan, P.J. (1972) In vitro transformation of Syrian hamster embryo cells by diverse chemical carcinogens. Nature, 235, 278-280.
15. Lasne, C., Gentil, A. and Chouroulinkov, I. (1974) Two stage malignant transformation of Syrian hamster cells. Nature, 247, 490-491.
16. Pienta, R.J., Poiley, J.A. and Lebherz, W.B. (1977) Morphological transformation of early passage golden Syrian hamster embryo cells derived from cryopreserved primary cultures as a reliable in vitro bioassay for identifying diverse carcinogens. Int. J. Cancer, 19, 642-655.
17. Barrett, J.C. (1980) A preneoplastic stage in the spontaneous neoplastic transformation of Syrian hamster embryo cells in culture. Cancer Res., 40, 91-94.
18. Barrett, J.C., Hesterberg, T.W. and Thomassen, D.G. (1984) Use of cell transformation systems for carcinogenicity testing and mechanistic studies of carcinogenesis. Pharmacol. Rev., 36, 53S-70S.
19. Tu, A. et al. (1986) An interlaboratory comparison of transformation in Syrian hamster embryo cells with model and coded chemicals. Environ. Mutagen., 8, 77-98.
20. LeBoeuf, R.A. and Kerckaert, G.A. (1986) The induction of transformed-like morphology and enhanced growth in Syrian hamster embryo cells grown at acidic pH. Carcinogenesis, 7, 1431-1440.
21. LeBoeuf, R.A., Kerckaert, G.A., Aardema, M.J. and Gibson, D.P. (1990) Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.70. Cancer Res., 50, 3722-3729.
22. Isfort, R.J., Kerckaert, G.A., Cody, D.B., Carter, J., Driscoll, K.E. and LeBoeuf, R.A. (1996) Isolation and biological characterization of morphological transformation-sensitive Syrian hamster embryo cells. Carcinogenesis, 17, 997-1005.
23. Klaunig, J.E. and Ruch, R.J. (1990) Biology of disease: role of inhibition of intercellular communication in carcinogenesis. Lab. Invest., 62, 135-146.
24. Trosko, J.E., Jone, C., and Chang, C.C. (1983) The role of tumor promoters on phenotypic alterations affecting intercellular communication and tumorigenesis. Ann. NY Acad. Sci., 407, 316-327.
25. Yamasaki, H. and Fitzgerald, D.J. (1988) The role of selective junctional communication in cell transformation. In Langenbach, R., Elmore, E. and Barrett, J.C. (eds) Tumor Promoters: Biological Approaches for Mechanistic Studies and Assay Systems. Raven Press, New York, NY, pp. 131-147.
26. Yamasaki, H. (1990) Gap junctional intercellular communication and carcinogenesis. Carcinogenesis, 11, 1051-1058.
27. Rivedal, E., Sanner, T., Enomoto, T. and Yamasaki, H. (1985) Inhibition of intercellular communication and enhancement of morphological transformation of Syrian hamster embryo cells by TPA. Use of TPA-sensitive and TPA-resistant cell lines. Carcinogenesis, 6, 899-902.
28. Ruch, R.J., Klaunig, J.E., Kerckaert, G.A. and LeBoeuf, R.A. (1990) Modification of gap junctional intercellular communication by changes in extracellular pH in Syrian hamster embryo cells. Carcinogenesis, 11, 909-913.
29. Mikalsen, S.-O. and Sanner, T. (1993) Intercellular communication in colonies of Syrian hamster embryo cells and the susceptibility for morphological transformation. Carcinogenesis, 14, 251-257.
30. Reddy, J.K. (1974) Hepatic microbody proliferation and catalase synthesis induced by methyl clofenapate, a hypolipidemic analog of CPIB. Am. J. Pathol., 75, 103-118.
31. Reddy J.K. and Qureshi S.A. (1979) Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-α-p-chlorophenoxyisobutyrate (clofibrate) in rats. Br. J. Cancer, 40, 476-482.
32. Mikalsen, S.-O., Holen, I. and Sanner, T. (1990) Morphological transformation and catalase activity of Syrian hamster embryo cells treated with peroxisome proliferators, TPA and nickel sulphate. Cell Biol. Toxicol., 6, 1-13.
33. Sanner, T., Mikalsen, S.-O. and Rivedal, E. (1991) Hepatic peroxisome proliferators induce morphologic transformation of Syrian hamster embryo cells, but not peroxisomal β oxidation. In Butterworth, B.E., Slaga, T.J., Farland, W. and McClain, M. (eds), Progress in Clinical and Biological Research, Vol. 369: Chemically Induced Cell Proliferation: Implications for Risk Assessement. Wiley-Liss, New York. pp. 77-89.
34. Trosko, J.E., Yotti, L.P., Warren, S.T., Tsushimoto, G. and Chang, C.C. (1982) Inhibition of cell-cell communication by tumor promoters. In Hecker, E., Fusenig, N.E., Kuntz, W., Marks, F. and Thielman, H.W. (eds) Carcinogenesis - A Comprehensive Survey, Vol. 7: Cocarcinogenesis and Biological Effects of Tumor Promoters. Raven Press, New York, NY, pp. 565-585.
35. Jansen, L.A.M. and Jongen, W.M.F. (1996) The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication. Carcinogenesis, 17, 333-339.
36. Elias, Z. et al. (1989) Cytotoxic and neoplastic transforming effects of industrial hexavalent chromium pigments in Syrian hamster embryo cells. Carcinogenesis, 10, 2043-2052.
37. Lasne, C., Lu, Y.R., Orfila, L., Ventura, L. and Chouroulinkov, I. (1990) Study of various transforming effects of the anabolic agents trenbolone and testosterone on Syrian hamster embryo cells. Carcinogenesis, 11, 541-547.
38. Bessi, H., Rast, C., Nguyen-Ba, G. and Vasseur, P. (1994) Chlorothalonil promotes morphological transformation in hamster embryo cells but does not inhibit gap junctional intercellular communication either in SHE cells or in the V79 cell line. Cancer J., 7, 248-253.
39. Bessi, H., Rast, C., Rether, B., Nguyen-Ba, G. and Vasseur, P. (1995) Synergistic effects of chlordane and TPA in multistage morphological transformation of SHE cells. Carcinogenesis. 16, 237-244.
40. Mochizuki, Y., Furukawa, K. and Sawada, N. (1982) Effects of various concentrations of ethyl-α-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat. Carcinogenesis, 3, 1027-1029.
41. Dhalluin, S., Cruciani, V., Rast, C., Vasseur, P., Tapiero, H. and Nguyen-Ba, G. (1996) Staged exposure of SHE cells to clofibrate and TPA: correlation between morphological transformation, omithine decarboxylase and metalloprotease activities. Cell. Pharmacol., 3, 23-28.
42. Lefevre, P.A. et al. (1994) Evaluation of the genetic toxicity of the peroxisome proliferator and carcinogen methyl clofenapate, including assays using Muta Mouse and Big Blue transgenic mice. Hum. Exp. Toxicol., 13, 764-775.
43. Moser, G.J. and Smart, R.C. (1989) Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity. Carcinogenesis, 10, 851-856.
44. Shackleton, G.L., Gibson, G.G., Sharma, R.K., Howes, D., Orrenius, S. and Kass, G.E.N. (1995) Diverse mechanisms of calcium mobilization by peroxisome proliferators in rat hepatocytes. Toxicol. Appl. Pharmacol., 130, 294-303.
45. Barrass, N.C, Price, R.J., Lake, B.G. and Orton, T.C. (1993) Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver. Carcinogenesis, 14, 1451-1456.
46. Styles, J.A., Kelly, M., Pritchard, N.R. and Elcombe, C.R. (1988) A species comparison of acute hyperplasia induced by the peroxisome proliferator methylclofenapate: involvement of the binucleated hepatocyte. Carcinogenesis, 9, 1647-1655.
47. Styles, J.A. (1993) Detection and quantification of ploidy, nuclearity, and DNA synthesis in rat hepatocytes after administration of a peroxisome proliferator. Environ. Hlth Perspect., 101, 225-228.
48. Roseng, L.E., Rivedal, E. and Sanner, T. (1993) 12-O-Tetradecanoylphorbol-13-acetate-induced inhibition of gap junctional communication is differentially regulated in a transformation-sensitive Syrian hamster embryo cell line compared to early passage SHE cells. Carcinogenesis, 14, 1851-1855.
49. Mikalsen, S.-O., Kaalhus, O., Reith, A. and Sanner, T. (1990) Role of catalase and oxidative stress in hepatic peroxisome proliferator-induced morphological transformation of Syrian hamster embryo cells. Int. J. Cancer, 46, 950-957.
50. Tsutsui, T., Watanabe, E. and Barrett, J.C. (1993) Ability of peroxisome proliferators to induce cell transformation, chromosome aberrations and peroxisome proliferation in cultured Syrian hamster embryo cells. Carcinogenesis, 14, 611-618.
51. Yotti, L.P., Chang, C.C. and Trosko, J.E. (1979) Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter. Science, 206, 1089-1091.