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Volumn 23, Issue , 1999, Pages S12-S18

Indirect measurement of mitochondrial proton leak and its application

Author keywords

Aging; Leptin (OB protein); Mitochondria; Muscle; Obese; Proton leak; Synaptosome (neuron); Thyroid hormone; Uncoupling proteins (UCPs)

Indexed keywords

ADENOSINE TRIPHOSPHATE; GUANOSINE DIPHOSPHATE; LEPTIN; LIOTHYRONINE; OLIGOMYCIN; PROTON; THYROID HORMONE; UNCOUPLING PROTEIN;

EID: 0033062789     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0800937     Document Type: Article
Times cited : (35)

References (53)
  • 1
    • 36949083936 scopus 로고
    • Coupling of phosphorylation to electron and hydrogen transfer by a chemisomotic type of mechanism
    • Mitchell P. Coupling of phosphorylation to electron and hydrogen transfer by a chemisomotic type of mechanism. Nature 1961; 191: 144-148.
    • (1961) Nature , vol.191 , pp. 144-148
    • Mitchell, P.1
  • 3
    • 0028010091 scopus 로고
    • Experimental discrimination between proton leak and redox slip during mitochondrial electron transport
    • Brand MD, Chien L-F, Diolez P. Experimental discrimination between proton leak and redox slip during mitochondrial electron transport. Biochem J 1994; 297: 27-29.
    • (1994) Biochem J , vol.297 , pp. 27-29
    • Brand, M.D.1    Chien, L.-F.2    Diolez, P.3
  • 4
    • 0029056231 scopus 로고
    • Mitochondrial proton conductance and H f/0 ratio are independent of electron traasport rate in isolated mitochondria
    • f/0 ratio are independent of electron traasport rate in isolated mitochondria. Biochem J 1995; 310: 379-382.
    • (1995) Biochem J , vol.310 , pp. 379-382
    • Porter, R.K.1    Brand, M.D.2
  • 5
    • 0022479238 scopus 로고
    • Changes in the permeability to protons and other cations at high proton motive force in rat liver mitochondria
    • Brown GC, Brand MD. Changes in the permeability to protons and other cations at high proton motive force in rat liver mitochondria. Biochem J 1986; 234: 75 - 81.
    • (1986) Biochem J , vol.234
    • Brown, G.C.1    Brand, M.D.2
  • 6
    • 0025007883 scopus 로고
    • Control of respiration and oxidative phosphorylation in isolated rat liver cells
    • Brown GC, Lakin-Thomas PL, Brand MD. Control of respiration and oxidative phosphorylation in isolated rat liver cells. EurJ Biochem 1990; 192: 355-362.
    • (1990) Eurj Biochem , vol.192 , pp. 355-362
    • Brown, G.C.1    Lakin-Thomas, P.L.2    Brand, M.D.3
  • 7
    • 0028802746 scopus 로고
    • A hierarchy of ATP-consuming processes in mammalian cells
    • Buttergereit F, Brand MD. A hierarchy of ATP-consuming processes in mammalian cells. Biochem J 1995; 312: 163-167
    • (1995) Biochem J , vol.312 , pp. 163-167
    • Buttergereit, F.1    Brand, M.D.2
  • 9
    • 0029976895 scopus 로고    scopus 로고
    • Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate
    • Rolfe DFS, Brand MD. Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate. Am J Physiol 1996; 271: C1380-C1389.
    • (1996) Am J Physiol , vol.271 , pp. C1380-C1389
    • Rolfe, D.F.S.1    Brand, M.D.2
  • 10
    • 0027480085 scopus 로고
    • Body mass dependence of H+ leak in motochondria and its relevance to metabolic rate
    • + leak in motochondria and its relevance to metabolic rate. Nature 1993; 362: 628-630.
    • (1993) Nature , vol.362 , pp. 628-630
    • Porter, R.K.1    Brand, M.D.2
  • 11
    • 0028884511 scopus 로고
    • Causes of differences in respiration rate of hepatocytes from mammals of different body mass
    • Porter RK, Brand MD. Causes of differences in respiration rate of hepatocytes from mammals of different body mass. Am J Physiol 1995; 269: R1213 -R1224.
    • (1995) Am J Physiol , vol.269 , pp. R1213-R1224
    • Porter, R.K.1    Brand, M.D.2
  • 12
    • 0025166707 scopus 로고
    • The contribution of the leak of protoas across the mitochondrial inner membrane to standard metabolic rate
    • Brand MD. The contribution of the leak of protoas across the mitochondrial inner membrane to standard metabolic rate.J Theor Biol 1990; 145: 267-286.
    • (1990) J Theor Biol , vol.145 , pp. 267-286
    • Brand, M.D.1
  • 14
    • 0027227273 scopus 로고
    • The quantitative contribution of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status
    • Harper M-E, Brand MD. The quantitative contribution of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status. J Biol Chem 1993; 268: 14850-14860.
    • (1993) J Biol Chem , vol.268 , pp. 14850-14860
    • Harper, M.-E.1    Brand, M.D.2
  • 15
    • 84984931751 scopus 로고
    • Acute leptin cffects on proton leak in ob/ob mice. FEBS Lett, submitted Chappell JB, Hansford
    • Bimie GD (ed)
    • Melia HP, Andrews JF, McBennett S, Porter RK. Acute leptin cffects on proton leak in ob/ob mice. FEBS Lett, submitted Chappell JB, Hansford RG. In: Bimie GD (ed). Subcellular components: preparation and fractionation 2nd edn. Butter- worths: London, 1972, pp 77-91.
    • (1972) FEBS Lett , pp. 77-91
    • Melia, H.P.1    Rews, J.F.2    McBennett, S.3    Porter, R.K.4
  • 16
    • 0025968684 scopus 로고
    • Isolation of skeletal muscle mitochondria from hamsters using an ionic medium containing ethylenediaminetetraacetic acid and nagarse
    • Bhattacharya SK, Thakar JH, Johnson PL, Shanklin DR. Isolation of skeletal muscle mitochondria from hamsters using an ionic medium containing ethylenediaminetetraacetic acid and nagarse. Anal Biochem 1991; 192: 344-349.
    • (1991) Anal Biochem , vol.192 , pp. 344-349
    • Bhattacharya, S.K.1    Thakar, J.H.2    Johnson, P.L.3    Shanklin, D.R.4
  • 17
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen P. Preparation of isolated rat liver cells. Method Cell Biol 1976; 13: 29-83.
    • (1976) Method Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.1
  • 18
    • 0002489040 scopus 로고
    • Isolation of synaptosomes, growth cones and their subcellular components
    • In Turner AJ, Backelard HS [eds), IRL Press: Oxford
    • Gordon-Weeks PR. Isolation of synaptosomes, growth cones and their subcellular components. In Turner AJ, Backelard HS [eds). Neurochemistry: a practical approach. IRL Press: Oxford, 1987, pp 1-26.
    • (1987) Neurochemistry: A Practical Approach , pp. 1-26
    • Gordon-Weeks, P.R.1
  • 19
    • 0002114258 scopus 로고
    • Measurement of mitochondrial protonmotive force
    • Brown GC, Cooper, IRL Press: Oxford
    • Brand MD. Measurement of mitochondrial protonmotive force. In: Brown GC, Cooper CE (eds). Bioenergetics: a practical approach. IRL Press: Oxford, 1995, pp 39-62.
    • (1995) Bioenergetics: A Practical Approach , pp. 39-62
    • Brand, M.D.1
  • 20
    • 0016413018 scopus 로고
    • The effect of age on mitochondrial ultrastructure and function
    • Wilson PD, Franks LM. The effect of age on mitochondrial ultrastructure and function. Adv Exp Med Biol 1975; 53: 171-183.
    • (1975) Adv Exp Med Biol , vol.53 , pp. 171-183
    • Wilson, P.D.1    Franks, L.M.2
  • 22
    • 0030060814 scopus 로고    scopus 로고
    • Ageing is associated in females with decline in the content and activity of b-C complex in skeletal muscle mitochondria
    • Boffoli D, Scacco SC, Vergati R, Persio MT, Solarino G, Laforgia R, Papa S. Ageing is associated in females with decline in the content and activity of b-C complex in skeletal muscle mitochondria. Biochim Biophys Acta 1996; 1315: 66-72.
    • (1996) Biochim Biophys Acta , vol.1315 , pp. 66-72
    • Boffoli, D.1    Scacco, S.C.2    Vergati, R.3    Persio, M.T.4    Solarino, G.5    Laforgia, R.6    Papa, S.7
  • 24
    • 0030581498 scopus 로고    scopus 로고
    • Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications
    • Papa S. Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications. Biochem Biophys Acta 1996; 1276: 87- 105.
    • (1996) Biochem Biophys Acta , vol.1276
    • Papa, S.1
  • 25
    • 0027949202 scopus 로고
    • Oxidative damage and mitochondrial decay in aging
    • Shigenga M, Hagen T, Ames B. Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci USA 1994;91:10771-10778.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10771-10778
    • Shigenga, M.1    Hagen, T.2    Ames, B.3
  • 26
    • 0026603840 scopus 로고
    • Cardiol ipins and biomembrane function
    • Hoch FL. Cardiol ipins and biomembrane function. Biochim Biophys Acta 1992; 1113: 71 -133.
    • (1992) Biochim Biophys Acta , vol.1113
    • Hoch, F.L.1
  • 27
    • 0030992498 scopus 로고    scopus 로고
    • Age- dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: Role of cardiolipin
    • Paradies G, Ruggiero FM, Petrosillo G, Quagliariello E. Age- dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: role of cardiolipin. FEBS Lett 1997; 406: 136-138.
    • (1997) FEBS Lett , vol.406 , pp. 136-138
    • Paradies, G.1    Ruggiero, F.M.2    Petrosillo, G.3    Quagliariello, E.4
  • 28
    • 0030444861 scopus 로고    scopus 로고
    • Allometry of mitochondrial proton leak: Influence of membrane surface and fatty acid composition
    • Porter RK, Hulbert AJ, Brand MD. Allometry of mitochondrial proton leak: influence of membrane surface and fatty acid composition. Am.J Physiol 1996; 271: R1550-R1560.
    • (1996) Am.J Physiol , vol.271 , pp. R1550-R1560
    • Porter, R.K.1    Hulbert, A.J.2    Brand, M.D.3
  • 30
    • 0031869858 scopus 로고    scopus 로고
    • Age- related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes
    • Harper M-E, Monemdjou S, Ramsey JJ, Weindruch R. Age- related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes. Am J Physiol 1998; 275: E197-E206.
    • (1998) Am J Physiol , vol.275 , pp. E197-E206
    • Harper, M.-E.1    Monemdjou, S.2    Ramsey, J.J.3    Weindruch, R.4
  • 31
  • 32
    • 0021799584 scopus 로고
    • Impairment of glutamate uptake and absence of alterations in the energy- transducing ability of old rat brain mitochondria
    • Vitorica J, Clark A, Machado A, Satrstegui J. Impairment of glutamate uptake and absence of alterations in the energy- transducing ability of old rat brain mitochondria. Mech Ageing Dev 1985; 29: 255-266.
    • (1985) Mech Ageing Dev , vol.29 , pp. 255-266
    • Vitorica, J.1    Clark, A.2    Machado, A.3    Satrstegui, J.4
  • 33
    • 0029936633 scopus 로고    scopus 로고
    • Metabolic rate, organ mass, and mitochondrial proton leak variations in lean and obese rats
    • Ramsey JJ, Johnson DE, Hossner KL, Johnson KA. Metabolic rate, organ mass, and mitochondrial proton leak variations in lean and obese rats. Comp Biochem Physiol 1996; 113B: 461-466.
    • (1996) Comp Biochem Physiol , vol.113B , pp. 461-466
    • Ramsey, J.J.1    Johnson, D.E.2    Hossner, K.L.3    Johnson, K.A.4
  • 35
    • 0030467446 scopus 로고    scopus 로고
    • The OB protein (Leptin) pathway-a link between adipose tissue mass and central neural networks
    • Campfield LA, Smith FJ, Bum P. The OB protein (leptin) pathway-a link between adipose tissue mass and central neural networks. Homi Metab Res 1996; 28: 619-632.
    • (1996) Homi Metab Res , vol.28 , pp. 619-632
    • Campfield, L.A.1    Smith, F.J.2    Bum, P.3
  • 36
    • 0019970087 scopus 로고
    • Studies on the activity of brown adipose tissue in suckling, pre-obese, ob/ob mice
    • Goodbody AE, Trayhurn P. Studies on the activity of brown adipose tissue in suckling, pre-obese, ob/ob mice. Biochim Biophys Acta 1982; 19: 119-126.
    • (1982) Biochim Biophys Acta , vol.19 , pp. 119-126
    • Goodbody, A.E.1    Trayhurn, P.2
  • 39
    • 0030869755 scopus 로고    scopus 로고
    • Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergie agonists, and leptin
    • Gong DW, He Y, Karas M, Reitman M. Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergie agonists, and leptin. J Biol Chem 1997; 272: 24129-34132.
    • (1997) J Biol Chem , vol.272 , pp. 24129-34132
    • Gong, D.W.1    He, Y.2    Karas, M.3    Reitman, M.4
  • 41
    • 0031821693 scopus 로고    scopus 로고
    • Leptin induction of UCP1 gene expression is dependent on synpathetic innervation
    • Scarpace PJ, Matheny M. Leptin induction of UCP1 gene expression is dependent on synpathetic innervation. Am J Physiol 1998; 275: E259-E264.
    • (1998) Am J Physiol , vol.275 , pp. E259-E264
    • Scarpace, P.J.1    Matheny, M.2
  • 43
    • 0017264191 scopus 로고
    • Hamster brown-adipose-tissue mitochondria
    • Nicholls DG. Hamster brown-adipose-tissue mitochondria. EurJ Biochem 1976; 62: 223-228.
    • (1976) Eurj Biochem , vol.62 , pp. 223-228
    • Nicholls, D.G.1
  • 44
    • 0028556635 scopus 로고
    • Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-coasuming tissues of the rat
    • Rolfe DFS, Hulbert AJ, Brand MD. Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-coasuming tissues of the rat. Biochem Biophys Acta 1994; 1118: 405-416.
    • (1994) Biochem Biophys Acta , vol.1118 , pp. 405-416
    • Rolfe, D.F.S.1    Hulbert, A.J.2    Brand, M.D.3
  • 47
    • 0030712088 scopus 로고    scopus 로고
    • Enhanced expression of uncoupling protein 2 gene in rat white adipose tissue and skeletal muscle following chronic treatment with thyroid hormone
    • Masaki T, Yoshimatsu H. Kakuma T, Hidaka S, Kurokawa M, Sakata T. Enhanced expression of uncoupling protein 2 gene in rat white adipose tissue and skeletal muscle following chronic treatment with thyroid hormone. FEBS Lett 1997; 418: 323-326.
    • (1997) FEBS Lett , vol.418 , pp. 323-326
    • Masaki, T.1    Yoshimatsu, H.2    Kakuma, T.3    Hidaka, S.4    Kurokawa, M.5    Sakata, T.6
  • 48
    • 0025861442 scopus 로고
    • The uncoupling protein UCP: A membraneous mitochondrial ion carrier in brown adipose tissue
    • Klaus S, Casteilla L, Bouillaud F, Ricquier D. The uncoupling protein UCP: a membraneous mitochondrial ion carrier in brown adipose tissue. Int J Biochem 1991; 23: 791-801.
    • (1991) Int J Biochem , vol.23 , pp. 791-801
    • Klaus, S.1    Casteilla, L.2    Bouillaud, F.3    Ricquier, D.4
  • 49
    • 0030881775 scopus 로고    scopus 로고
    • Identification by site-directed mutagenesis of three arginines in uncoupling protein that are essential for nucleotide binding and inhibition
    • Modriaask’y M, Murdza-Inglis DL, Patel HV, Freeman KB, Garlid KD. Identification by site-directed mutagenesis of three arginines in uncoupling protein that are essential for nucleotide binding and inhibition. J Biol Chem 1998; 40: 24759-24762.
    • (1998) J Biol Chem , vol.40 , pp. 24759-24762
    • Modriaask’Y, M.1    Murdza-Inglis, D.L.2    Patel, H.V.3    Freeman, K.B.4    Garlid, K.D.5
  • 50
    • 84984929018 scopus 로고    scopus 로고
    • Comparison of oxidative phosphorylation in isolated liver mitochondria from young and old rats
    • submitted
    • Melia HP, Jensen CH, Lund MD, Porter RK. Comparison of oxidative phosphorylation in isolated liver mitochondria from young and old rats. J Biol Chem, submitted.
    • J Biol Chem
    • Melia, H.P.1    Jensen, C.H.2    Lund, M.D.3    Porter, R.K.4
  • 51
    • 0018864653 scopus 로고
    • Energy transduction in intact synapto- somes
    • Scott ID, Nicholls DG. Energy transduction in intact synapto- somes. Biochem J 1980; ÌSÓ^: 21-33.
    • (1980) Biochem J
    • Scott, I.D.1    Nicholls, D.G.2
  • 53
    • 0344947594 scopus 로고    scopus 로고
    • The effect of thyroid administration on rat skeletal mitochondrial proton leak
    • Melia HP, Porter RK. The effect of thyroid administration on rat skeletal mitochondrial proton leak. Biochem Biophys Res Commun, submitted.
    • Biochem Biophys Res
    • Melia, H.P.1    Porter, R.K.2


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