The identification of three biologically relevant globotriaosyl ceramide receptor binding sites on the Verotoxin 1 B subunit

Molecular Microbiology

Volumn 32, Issue 5, 1999, Pages 953-960

  Bast, D J ^a,b   Banerjee, L ^a,b   Clark, C ^c   Read, R J ^d,e   Brunton, J L ^a,b,f,g  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c LAB CENTRE FOR DISEASE CONTROL   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f TORONTO GENERAL HOSPITAL   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DISACCHARIDE; GLOBOTRIAOSYLCERAMIDE; GLYCOSPHINGOLIPID; MONOMER; RECEPTOR; RECEPTOR SUBUNIT; VEROTOXIN;

ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; COMPUTER MODEL; CRYSTALLOGRAPHY; CYTOTOXICITY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SCATCHARD PLOT;

ANIMALS; BACTERIAL TOXINS; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, THIN LAYER; ESCHERICHIA COLI; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, CELL SURFACE; SHIGA-LIKE TOXIN I; STRUCTURE-ACTIVITY RELATIONSHIP; TRIHEXOSYLCERAMIDES; VERO CELLS;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0033062483     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1999.01405.x     Document Type: Article

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