메뉴 건너뛰기




Volumn 434, Issue 2, 1999, Pages 109-117

PCR assay of DNA damage and repair at the gene level in brain and spleen of γ-irradiated young and old rats

Author keywords

Irradiated rats; Aging; DNA damage; PCR assay; Repair in vivo

Indexed keywords

BETA ACTIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN P53;

EID: 0033061528     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(99)00019-1     Document Type: Article
Times cited : (20)

References (50)
  • 1
    • 0024343128 scopus 로고
    • DNA damage and repair during cellular aging
    • Rattan S.S. DNA damage and repair during cellular aging. Review of Cytology. 116:1989;47-88.
    • (1989) Review of Cytology , vol.116 , pp. 47-88
    • Rattan, S.S.1
  • 3
    • 0030874916 scopus 로고    scopus 로고
    • Role of transposable elements in age-related genomic instability
    • Nikitin A.G., Shmookler Reis R.J. Role of transposable elements in age-related genomic instability. Genet. Res. 69:1997;183-195.
    • (1997) Genet. Res. , vol.69 , pp. 183-195
    • Nikitin, A.G.1    Shmookler Reis, R.J.2
  • 4
    • 0001852178 scopus 로고
    • Alterations in gene expression with aging
    • in: E.L. Schneider, J.W. Rowe (Eds.), Academic Press, San Diego
    • D.B. Danner, N.J. Holbrook, Alterations in gene expression with aging, in: E.L. Schneider, J.W. Rowe (Eds.), Handbook of the Biology of Aging, 3rd edn., Academic Press, San Diego, 1990, pp. 97-115.
    • (1990) Handbook of the Biology of Aging, 3rd Edn. , pp. 97-115
    • Danner, D.B.1    Holbrook, N.J.2
  • 5
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78:1998;547-581.
    • (1998) Physiol. Rev. , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 7
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley C.B., Futcher A.B., Greider C.W. Telomeres shorten during ageing of human fibroblasts. Nature (London). 345:1990;458-460.
    • (1990) Nature (London) , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 9
    • 0029165277 scopus 로고
    • DNA damage, mutation and fine structure DNA repair in aging
    • Bohr V.A., Anson R.M. DNA damage, mutation and fine structure DNA repair in aging. Mutat. Res. 338:1995;25-34.
    • (1995) Mutat. Res. , vol.338 , pp. 25-34
    • Bohr, V.A.1    Anson, R.M.2
  • 12
    • 0030042134 scopus 로고    scopus 로고
    • Role of induced genetic instability in the mutagenic effects of chemicals and radiation
    • Murnane J.P. Role of induced genetic instability in the mutagenic effects of chemicals and radiation. Mutat. Res. 367:1996;11-23.
    • (1996) Mutat. Res. , vol.367 , pp. 11-23
    • Murnane, J.P.1
  • 13
    • 0021905437 scopus 로고
    • DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall
    • Bohr V.A., Smith C.A., Okumoto D.S., Hanawalt P.C. DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell. 40:1985;359-369.
    • (1985) Cell , vol.40 , pp. 359-369
    • Bohr, V.A.1    Smith, C.A.2    Okumoto, D.S.3    Hanawalt, P.C.4
  • 14
    • 0025898481 scopus 로고
    • Heterogeneity of DNA repair at the gene level
    • Hanawalt P.C. Heterogeneity of DNA repair at the gene level. Mutat. Res. 247:1991;203-211.
    • (1991) Mutat. Res. , vol.247 , pp. 203-211
    • Hanawalt, P.C.1
  • 15
    • 0026000368 scopus 로고
    • Gene specific DNA repair
    • Bohr V.A. Gene specific DNA repair. Carcinogenesis. 12:1991;1983-1992.
    • (1991) Carcinogenesis , vol.12 , pp. 1983-1992
    • Bohr, V.A.1
  • 16
    • 0029892790 scopus 로고    scopus 로고
    • DNA excision repair
    • Sancar A. DNA excision repair. Annu. Rev. Biochem. 65:1996;43-81.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 43-81
    • Sancar, A.1
  • 17
    • 0030013201 scopus 로고    scopus 로고
    • Relationships between DNA repair and transcription
    • Friedberg E.C. Relationships between DNA repair and transcription. Annu. Rev. Biochem. 65:1996;15-42.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 15-42
    • Friedberg, E.C.1
  • 18
    • 0032539477 scopus 로고    scopus 로고
    • 6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea
    • 6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea. Proc. Natl. Acad. Sci. U.S.A. 95:1998;1635-1640.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 1635-1640
    • Engelbergs, J.1    Thomale, J.2    Galhoff, A.3    Rajewsky, M.F.4
  • 19
    • 0021747133 scopus 로고
    • Age changes of chromatin. A review
    • Medvedev Z.A. Age changes of chromatin. A review. Mech. Ageing Dev. 28:1984;139-154.
    • (1984) Mech. Ageing Dev. , vol.28 , pp. 139-154
    • Medvedev, Z.A.1
  • 21
    • 0000530035 scopus 로고
    • Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo
    • Gupta R.C. Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc. Natl. Acad. Sci. U.S.A. 81:1984;6943-6947.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 6943-6947
    • Gupta, R.C.1
  • 24
    • 0027153571 scopus 로고
    • Structure of the rat p53 tumor suppressor gene
    • Hulla J.E., Schneider R.P. Structure of the rat p53 tumor suppressor gene. Nucleic Acids Res. 21:1993;713-717.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 713-717
    • Hulla, J.E.1    Schneider, R.P.2
  • 25
    • 0029738835 scopus 로고    scopus 로고
    • P53 Accumulation in various organs of rats after whole-body exposure to low-dose X-ray irradiation
    • Wang X., Matsumoto H., Okaichi K., Ohnishi T. p53 Accumulation in various organs of rats after whole-body exposure to low-dose X-ray irradiation. Anticancer Res. 16:1996;1671-1674.
    • (1996) Anticancer Res. , vol.16 , pp. 1671-1674
    • Wang, X.1    Matsumoto, H.2    Okaichi, K.3    Ohnishi, T.4
  • 26
    • 0345048185 scopus 로고    scopus 로고
    • Polymerase chain reaction assay for measuring ionizing radiation induced DNA damage
    • in press
    • I.I. Ploskonosova, V.I. Baranov, A.I. Gaziev, Polymerase chain reaction assay for measuring ionizing radiation induced DNA damage, Radiation Res. (1999), in press.
    • (1999) Radiation Res.
    • Ploskonosova, I.I.1    Baranov, V.I.2    Gaziev, A.I.3
  • 27
    • 0025877161 scopus 로고
    • Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Tag DNA polymerase
    • Ponti M., Forrow S.M., Souhami R.L., D'Incalci M., Hartley J.A. Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Tag DNA polymerase. Nucleic Acids Res. 19:1991;2929-2933.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 2929-2933
    • Ponti, M.1    Forrow, S.M.2    Souhami, R.L.3    D'Incalci, M.4    Hartley, J.A.5
  • 28
    • 0025939726 scopus 로고
    • A polymerase chain reaction-based method to detect cisplatin adducts in specific genes
    • Jennerwein M.M., Eastman A. A polymerase chain reaction-based method to detect cisplatin adducts in specific genes. Nucleic Acids Res. 19:1991;6209-6214.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 6209-6214
    • Jennerwein, M.M.1    Eastman, A.2
  • 29
    • 0026708608 scopus 로고
    • Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay
    • Kalinowski D.P., Illenye S., Van Houten B. Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay. Nucleic Acids Res. 20:1992;3485-3494.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 3485-3494
    • Kalinowski, D.P.1    Illenye, S.2    Van Houten, B.3
  • 30
    • 0028308717 scopus 로고
    • Rapid polymerase assay to detect variation in the extent of gene-specific damage between cisplatin- Or VP-16-resistant and sensitive lung cancer cells lines
    • Oshita F., Saijo N. Rapid polymerase assay to detect variation in the extent of gene-specific damage between cisplatin- or VP-16-resistant and sensitive lung cancer cells lines. Jpn. J. Cancer Res. 85:1994;669-673.
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 669-673
    • Oshita, F.1    Saijo, N.2
  • 31
    • 0029915021 scopus 로고    scopus 로고
    • Modified quantitative polymerase chain reaction assay for measuring gene-specific repair of UV photoproducts in human cells
    • McCarthy M.J., Rosenblatt J.I., Lloyd R.S. Modified quantitative polymerase chain reaction assay for measuring gene-specific repair of UV photoproducts in human cells. Mutat. Res. 363:1996;57-66.
    • (1996) Mutat. Res. , vol.363 , pp. 57-66
    • McCarthy, M.J.1    Rosenblatt, J.I.2    Lloyd, R.S.3
  • 32
    • 0031230501 scopus 로고    scopus 로고
    • Kinetics of repair of UV-induced DNA damage in repair-proficient and -deficient cells as determined by quantitative polymerase chain reaction
    • McCarthy M.J., Rosenblatt J.I., Lloyd R.S. Kinetics of repair of UV-induced DNA damage in repair-proficient and -deficient cells as determined by quantitative polymerase chain reaction. Photochem. Photobiol. 66:1997;356-362.
    • (1997) Photochem. Photobiol. , vol.66 , pp. 356-362
    • McCarthy, M.J.1    Rosenblatt, J.I.2    Lloyd, R.S.3
  • 33
    • 0029128743 scopus 로고
    • Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated polymerase chain reaction
    • Rodriguez, Drouin R., Holmquist G.P., O'Connor T.R., Boiteux S., Laval J., Doroshow J.H., Akman S.A. Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated polymerase chain reaction. J. Biol. Chem. 270:1995;17633-17640.
    • (1995) J. Biol. Chem. , vol.270 , pp. 17633-17640
    • Rodriguez1    Drouin, R.2    Holmquist, G.P.3    O'Connor, T.R.4    Boiteux, S.5    Laval, J.6    Doroshow, J.H.7    Akman, S.A.8
  • 34
    • 0031441858 scopus 로고    scopus 로고
    • Preferential mitochondrial DNA injury caused by glucose oxidase as a steady generator of hydrogen peroxide in human fibroblasts
    • Salazar J.J., Van Houten B. Preferential mitochondrial DNA injury caused by glucose oxidase as a steady generator of hydrogen peroxide in human fibroblasts. Mutat. Res. 385:1997;139-149.
    • (1997) Mutat. Res. , vol.385 , pp. 139-149
    • Salazar, J.J.1    Van Houten, B.2
  • 35
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • Yakes F.M., Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. U.S.A. 94:1997;514-519.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 514-519
    • Yakes, F.M.1    Van Houten, B.2
  • 36
    • 0028266940 scopus 로고
    • DNA replication fidelity with 8-oxodeoxyguanosine triphosphate
    • Pavlov Y.I., Minnick D.T., Izuta S., Kunkel T.A. DNA replication fidelity with 8-oxodeoxyguanosine triphosphate. Biochemistry. 33:1994;4695-4701.
    • (1994) Biochemistry , vol.33 , pp. 4695-4701
    • Pavlov, Y.I.1    Minnick, D.T.2    Izuta, S.3    Kunkel, T.A.4
  • 37
    • 0029869449 scopus 로고    scopus 로고
    • An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues
    • Zaccolo M., Williams D.M., Brown D.M., Gherardi E. An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. J. Mol. Biol. 255:1996;589-603.
    • (1996) J. Mol. Biol. , vol.255 , pp. 589-603
    • Zaccolo, M.1    Williams, D.M.2    Brown, D.M.3    Gherardi, E.4
  • 38
    • 0029131290 scopus 로고
    • The somatic mutation theory of ageing
    • Morley A.A. The somatic mutation theory of ageing. Mutat. Res. 338:1995;19-23.
    • (1995) Mutat. Res. , vol.338 , pp. 19-23
    • Morley, A.A.1
  • 40
    • 0029892791 scopus 로고    scopus 로고
    • DNA repair in eukaryotes
    • Wood R.D. DNA repair in eukaryotes. Annu. Rev. Biochem. 65:1996;135-167.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 135-167
    • Wood, R.D.1
  • 41
    • 0027379353 scopus 로고
    • Preferential repair of ionizing radiation-induced damage in transcribed strand of an active human gene is defective in Cockayne syndrome
    • Leadon S.A., Lawrence D.A. Preferential repair of ionizing radiation-induced damage in transcribed strand of an active human gene is defective in Cockayne syndrome. Proc. Natl. Acad. Sci. U.S.A. 90:1993;10499-10503.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10499-10503
    • Leadon, S.A.1    Lawrence, D.A.2
  • 42
    • 0027870441 scopus 로고
    • The repair of γ-ray-induced single-strand breaks in transcribed and nontranscribed DNA of Hela cells
    • Igusheva O.A., Bildin V.N., Zhestyanikov V.D. The repair of γ-ray-induced single-strand breaks in transcribed and nontranscribed DNA of Hela cells. Cytology. 35:1993;54-63.
    • (1993) Cytology , vol.35 , pp. 54-63
    • Igusheva, O.A.1    Bildin, V.N.2    Zhestyanikov, V.D.3
  • 43
    • 0029616307 scopus 로고
    • Ionizing radiation-induced DNA strand breakage and rejoining in specific genomic regions as determined by an alkaline unwinding/Southern blotting method
    • Bunch R.T., Gewirtz D.A., Povirk L.F. Ionizing radiation-induced DNA strand breakage and rejoining in specific genomic regions as determined by an alkaline unwinding/Southern blotting method. Int. J. Radiat. Biol. 68:1995;553-562.
    • (1995) Int. J. Radiat. Biol. , vol.68 , pp. 553-562
    • Bunch, R.T.1    Gewirtz, D.A.2    Povirk, L.F.3
  • 44
    • 0002059397 scopus 로고    scopus 로고
    • Repair of ionizing radiation induced DNA double-strand breaks at the c-myc locus in comparison to the overall genome
    • Sak A., Stuschke M. Repair of ionizing radiation induced DNA double-strand breaks at the c-myc locus in comparison to the overall genome. Int. J. Radiat. Biol. 73:1998;35-43.
    • (1998) Int. J. Radiat. Biol. , vol.73 , pp. 35-43
    • Sak, A.1    Stuschke, M.2
  • 45
    • 0028865245 scopus 로고
    • Posttranslational modification of poly(ADP-ribose) polymerase induced by strand breaks
    • Lindahl T., Saton M.S., Poirier G.G., Klungland A. Posttranslational modification of poly(ADP-ribose) polymerase induced by strand breaks. Trends Biochem. Sci. 20:1995;405-411.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 405-411
    • Lindahl, T.1    Saton, M.S.2    Poirier, G.G.3    Klungland, A.4
  • 46
    • 0042909652 scopus 로고    scopus 로고
    • Catalytic activity of poly (ADP-ribose) polymerase is necessary for repair of N-methylpurines in nontranscribed, but not in transcribed, nuclear DNA sequences
    • Ray L.S., Chatterjee S., Berger N.A., Grishko V.I., LeDoux S.P., Wilson G.L. Catalytic activity of poly (ADP-ribose) polymerase is necessary for repair of N-methylpurines in nontranscribed, but not in transcribed, nuclear DNA sequences. Mutat. Res. 363:1996;105-114.
    • (1996) Mutat. Res. , vol.363 , pp. 105-114
    • Ray, L.S.1    Chatterjee, S.2    Berger, N.A.3    Grishko, V.I.4    Ledoux, S.P.5    Wilson, G.L.6
  • 47
    • 0029096509 scopus 로고
    • Dietary supplements of antioxidants reduce hprt mutant frequency in splenocytes of aging mice
    • Gaziev A.I., Podlutsky A.J., Panfilov B.M., Bradbury R.J. Dietary supplements of antioxidants reduce hprt mutant frequency in splenocytes of aging mice. Mutat. Res. 338:1995;77-86.
    • (1995) Mutat. Res. , vol.338 , pp. 77-86
    • Gaziev, A.I.1    Podlutsky, A.J.2    Panfilov, B.M.3    Bradbury, R.J.4
  • 48
    • 1642268993 scopus 로고    scopus 로고
    • The effect of donor age on the processing of UV-damaged DNA by cultured human cells: Reduced DNA repair capacity and increased DNA mutability
    • Moriwaki S.I., Ray S., Tarone R.E., Kraemer K.H., Grossman L. The effect of donor age on the processing of UV-damaged DNA by cultured human cells: reduced DNA repair capacity and increased DNA mutability. Mutat. Res. 364:1996;117-123.
    • (1996) Mutat. Res. , vol.364 , pp. 117-123
    • Moriwaki, S.I.1    Ray, S.2    Tarone, R.E.3    Kraemer, K.H.4    Grossman, L.5
  • 49
    • 0027081044 scopus 로고
    • Poly (ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span
    • Grube K., Burkle A. Poly (ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span. Proc. Natl. Acad. Sci. U.S.A. 89:1992;11759-11763.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 11759-11763
    • Grube, K.1    Burkle, A.2
  • 50
    • 0020954797 scopus 로고
    • DNA repair kinetics in irradiated undifferentiated and terminally differentiated cells
    • Wheeler K.T., Wierowski J.V. DNA repair kinetics in irradiated undifferentiated and terminally differentiated cells. Radiat. Environ. Biophys. 22:1983;3-19.
    • (1983) Radiat. Environ. Biophys. , vol.22 , pp. 3-19
    • Wheeler, K.T.1    Wierowski, J.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.