Exogenous control of cardiac gene therapy: Evidence of regulated myocardial transgene expression after adenovirus and adeno-associated virus transfer of expression cassettes containing corticosteroid response element promoters

Journal of Thoracic and Cardiovascular Surgery

Volumn 118, Issue 1, 1999, Pages 26-34

  Lee, L Y ^a   Zhou, X ^a   Polce, D R ^a   El Sawy, T ^a   Patel, S R ^a   Thakker, G D ^a   Narumi, K ^a   Crystal, R G ^a   Rosengart, T K ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CORTICOSTEROID; DEXAMETHASONE; GLUCOCORTICOID; LUCIFERASE; THROMBOPOIETIN; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE CASSETTE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HEART MUSCLE; HORMONE RESPONSIVE ELEMENT; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPORTER GENE; THROMBOCYTE COUNT; TRANSGENE;

EID: 0033060305     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(99)70137-6     Document Type: Article

References (29)

1. WF. Anderson Human gene therapy Science 256 1992 808 813
2. TR Flotte BJ. Carter Adeno-associated virus vectors for gene therapy Gene Ther 2 1995 357 362
3. D Gal L Weir G Leclerc JG Pickering J Hogan JM. Isner Direct myocardial transfection in two animal models: evaluation of parameters affecting gene expression and percutaneous gene delivery Lab Invest 68 1993 18 25
4. FJ Giordano P Ping MD McKirnan S Nozaki AN DeMaria WH Dillmann Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in ischemic region of the heart Nat Med 2 1996 534 539
5. CA Mack SR Patel EA Schwarz P Zanzonico RT Hahn A Ilercil Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart J Thorac Cardiovasc Surg 115 1998 168 176
6. LY Lee X Zhou SR Patel Prolonged transgene expression in the rat myocardium mediated by an adeno-associated viral vector: implications for chronic cardiac therapy Surg Forum 49 1998 215 216
7. M Boshart F Weber G Jahn K Dorsch-Hasler B Fleckenstein W. Schaffner A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus Cell 41 1985 521 530
8. HM Jantzen U Strähle B Gloss F Stewart W Schmid M Boshart Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene Cell 49 1987 29 38
9. K Narumi M Suzuki W Song MA Moore RG. Crystal Intermittent, repetitive corticosteroid-induced upregulation of platelet levels after adenovirus-mediated transfer to the liver of a chimeric glucocorticoid-responsive promoter controlling the thrombopoietin cDNA Blood 92 1998 822 833
10. J Hersh RG Crystal B. Bewig Modulation of gene expression after replication-deficient, recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector Gene Ther 2 1995 124 131
11. MA Rosenfeld K Yoshimura BC Trapnell K Yoneyama ER Rosenthal W Dalemans In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium Cell 68 1992 143 155
12. RG Crystal NG McElvaney MA Rosenfeld CS Chu A Mastrangeli JG Hay Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis Nat Genet 8 1994 42 51
13. X Xiao J Li RJ. Samulski Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus J Virol 72 1998 2224 2232
14. SK McLaughlin P Collis PL Hermonat N. Muzyczka Adeno-associated virus general transduction vectors: analysis of proviral structures J Virol 62 1988 1963 1973
15. PM Buttrick ML Kaplan RN Kitsis LA. Leinwand Distinct behavior of cardiac myosin heavy chain gene constructs in vivo: discordance with in vitro results Circ Res 72 1993 1211 1217
16. JM Chirgwin AE Przybyla RJ MacDonald WJ. Rutter Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease Biochemistry 18 1979 5294 5299
17. JY Tso XH Sun TH Kao KS Reece R. Wu Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene Nucleic Acids Res 13 1985 2485 2502
18. PS. Thomas Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose Proc Natl Acad Sci U S A 77 1980 5201 5205
19. RN Kitsis PM Buttrick EM McNally ML Kaplan LA. Leinwand Hormonal modulation of a gene injected into rat heart in vivo Proc Natl Acad Sci U S A 88 1991 4138 4142
20. JA Forsythe BH Jiang NV Iyer F Agani SW Leung RD Koos Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 Mol Cell Biol 16 1996 4604 4613
21. BA French W Mazur RS Geske R. Bolli Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors Circulation 90 1994 2414 2424
22. Y Yang SE Haecker Q Su JM. Wilson Immunology of gene therapy with adenoviral vectors in mouse skeletal muscle Hum Mol Genet 5 1996 1703 1712
23. ML Springer AS Chen PE Kraft M Bednarski HM. Blau VEGF gene delivery to muscle: potential role for vasculogenesis in adults Mol Cell 2 1998 549 558
24. DY Ho JR McLaughlin RM. Sapolsky Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system Brain Res Mol Brain Res 41 1996 200 209
25. M Suzuki RN Singh RG. Crystal Regulatable promoters for use in gene therapy applications: modification of the 5'-flanking region of the CFTR gene with multiple camp response elements to support basal, low-level gene expression that can be upregulated by exogenous agents that raise intracellular levels of cAMP Hum Gene Ther 7 1996 1883 1893
26. DE Hallahan HJ Mauceri LP Seung EJ Dunphy JD Wayne NN Hanna Spatial and temporal control of gene therapy using ionizing radiation Nat Med 1 1995 786 791
27. Y Hayashi AM DePaoli CF Burant S. Refetoff Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor J Biol Chem 269 1994 23872 23875
28. AW Varley MG Coulthard RS Meidell RD Gerard RS. Munford Inflammation-induced recombinant protein expression in vivo using promoters from acute-phase protein genes Proc Natl Acad Sci U S A 92 1995 5346 5350
29. G Gazit SE Kane P Nichols AS. Lee Use of the stress-inducible grp78/bip promoter in targeting high level gene expression in fibrosarcoma in vivo Cancer Res 55 1995 1660 1663