Impact of the type and severity of dementia on hospitalization and survival of the elderly

Dementia and Geriatric Cognitive Disorders

Volumn 10, Issue 2, 1999, Pages 121-129

  Landi, Francesco ^a   Gambassi, Giovanni ^a,b,c   Lapane, Kate L ^b   Sgadari, Antonio ^a   Mor, Vincent ^b   Bernabei, Roberto ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b BROWN UNIVERSITY   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Comorbidity; Elderly; Long term care; Minimum data set; Outcome; Vascular dementia

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; COGNITIVE DEFECT; COHORT ANALYSIS; COMORBIDITY; FEMALE; HEALTH STATUS; HOSPITALIZATION; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MEDICARE; MORBIDITY; MORTALITY; MULTIINFARCT DEMENTIA; NURSING HOME; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; UNITED STATES;

AGE FACTORS; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; COGNITION; COMORBIDITY; DEMENTIA, VASCULAR; FEMALE; HOSPITALIZATION; HUMANS; MALE; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; UNITED STATES;

EID: 0033060128     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000017112     Document Type: Article

References (56)

1. Advisory Panel on Alzheimer's Disease and related dementias: Acute and long term care services. NIH Publ No 96-4136. Washington, Superintendent of Documents, US Government Printing Office, 1996.
2. Small GW, Rabins PV, Barry PP, Buckholtz NS, DeKosky ST, Ferris SH, Finkel SI, Gwyther LP, Khachaturian ZS, Lebowitz BD, McRae TD, Morris JC, Oakley F, Schneider LS, Streim JE, Sunderland T, Teri LA, Tune LE: Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatric Society. JAMA 1997;278:1363-1371.
3. Walsh JS, Welch HG, Larson EB: Survival of outpatients with Alzheimer-type of dementia. Ann Intern Med 1990;113:429-434.
4. Goldmacher DS, Whitehouse PJ: Evaluation of dementia. N Engl J Med 1996;335:330-336.
5. Guralnik JM: Assessing the impact of comorbidity in the older population. Ann Epidemiol 1996;6:376-380.
6. Manton KG, Cornelius ES, Woodbury MA: Nursing home residents: A multivariate analysis of their medical, behavior, psychological, and service use characteristics. J Gerontol 1995;50:M242-M251.
7. Landi F, Gambassi G, Lapane KL, Sgadari A, Gifford D, Mor V, Bernabei R: Comorbidity and drug use in cognitively impaired elderly living in long-term care. Dement Geriatr Cogn Disord 1998;9:347-356.
8. Wolf-Klein GP, Silverstone FA, Brod MS, Levy A, Foley CJ, Breur J: Are Alzheimer patients healthier? J Am Geriatr Soc 1988;36: 219-224.
9. Holstein J, Chatellier G, Piette F, Moulias R: Prevalence of associated diseases in different type of dementia among elderly institutionalized patients: Analysis of 3,447 records. J Am Geriatr Soc 1994;42:972-977.
10. Nielson KA, Nolan JH, Berchtold NC, Sandman CA, Mulnard RA, Cotman CW: Apolipoprotein-E genotyping of diabetic dementia patients: Is diabetes rare in Alzheimer's disease? J Am Geriatr Soc 1996;44:897-904.
11. Semla TP, Cohen D, Paveza G, Eisdorfer C, Gorelick P, Luchins D, Hirschman R, Freels S, Levy P, Ashford W, Shaw H: Drug use patterns of persons with Alzheimer's disease and related disorders living in the community. J Am Geriatr Soc 1993;41:408-413.
12. Hanlon JT, Landerman LR, Wall WE, Horner RD, Fillenbaum GG, Dawson DV, Schmader KE, Cohen HJ, Blazer DG: Is medication use by community-dwelling elderly people influenced by cognitive function? Age Ageing 1996;25:190-196.
13. Wills P, Claesson CB, Fratiglioni L, Fastbom J, Thorslund M, Winblad B: Drug use by demented and non-demented elderly people. Age Ageing 1997;26:383-391.
14. Bernabei R, Gambassi G, Mor V: The SAGE database: Introducing functional outcomes in geriatric pharmaco-epidemiology. J Am Geriatr Soc 1998;46:251-252.
15. Bernabei R, Gambassi G, Lapane K, Sgadari A. Landi F, Gatsonis C, Lipsitz L, Mor V: Characteristics of the SAGE database: A new resource for research on outcomes in long-term care. J Gerontol 1999;54A:M25-M33.
16. Gambassi G, Landi F, Peng L, Brostrup-Jensen C, Calore K, Hiris J, Lipsitz L, Mor V, Bernabei R: Validity of diagnostic and drug data in standardized nursing home resident assessments: Potential for geriatric pharmacoepidemiology. Med Care 1998;36:167-179.
17. Bernabei R, Gambassi G, Lapane K, Landi F, Gatsonis C, Dunlop R, Lipsitz L, Steel K, Mor V: Management of pain in elderly cancer patients. JAMA 1998;279:1877-1882.
18. Gambassi G, Lapane K, Sgadari A, Landi F, Carbonin PU, Hume A, Lipsitz L, Mor V, Bernabei R: Prevalence, clinical correlates and treatment of hypertension in elderly nursing home residents. Arch Intern Med 1998,158: 2377-2385.
19. Mor V, Branco K, Fleishman J, Hawes C, Phillips C, Morris JN, Fries BE: The structure of social engagement among nursing home residents. J Gerontol 1995;50B:P1-P8.
20. Morris JN, Fries BE, Meher DR, Hawes C, Phillips C, Mor V, Lipsitz L: MDS Cognitive Performance Scale. J Gerontol 1994;49:M174-M182.
21. Phillips CD, Morris JN, Hawes C, Fries BE, Mor V, Nennstiel M, Iannacchionc V: Association of the Resident Assessment Instrument (RAI) with changes in function, cognition, and psycho-social status. J Am Geriatr Soc 1997; 45:986-993.
22. Hartmaier SL, Sloane PD, Guess HA, Koch GC, Mitchell CM, Phillips CD: Validation of the Minimum Data Set Cognitive Performance Scale: Agreement with the Mini-Mental State Examination. J Gerontol 1995;50:M128-M133.
23. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, ed 4. Washington, American Psychiatric Association, 1994.
24. Phillips CD, Morris JN: The potential use of administrative and clinical data to analyze outcomes for the cognitively impaired. Alzheimer Dis Assoc Disord, in press.
25. Hogan DB, Ebly EM, Rockwood K: Weight, blood pressure, osmolarity, and glucose levels across various stages of Alzheimer's disease and vascular dementia. Dement Geriatr Cogn Disord 1997;8:147-151.
26. VanDijk PT, Dippel DW, VanDerMeulen JH, Habbema JD: Comorbidity and its effect on mortality in nursing home patients with dementia. J Nerv Ment Dis 1996;184:180-187.
27. Dinkel RH, Lehok UH: The effect of dementia in German acute care hospital. Dement Geriatr Cogn Disord 1997;8:314-319.
28. Callahan CM, Hendrie HC, Tierney WM: Documentation and evaluation of cognitive impairment in elderly primary care patients. Ann Intern Med 1995;122:422-429.
29. Landin K, Blennow K, Wallin A, Gottfries CG: Low blood pressure and blood glucose levels in Alzheimer's disease: Evidence for a hypometabolic disorder? J Intern Med 1993;233:357-363.
30. Thorpe J, Widman LP, Wallin A, Beiswanger J, Blumenthal HT: Comorbidity of other chronic age-dependent diseases in dementia. Aging Clin Exp Res 1994;6:159-166.
31. Halter JB: Alzheimer's disease and non-insulin-dependent diabetes mellitus: Common features do not make common bedfellows. J Am Geriatr Soc 1996;44:992-993.
32. Landi F, Bernabei R, Gambassi G: Non-insulin-dependent diabetes mellitus and Alzheimer's disease. J Am Geriatr Soc 1997;45:654-655.
33. Stewart WF, Kawas C, Corrada M, Metter EJ: Risk of Alzheimer's disease and duration of NSAID use. Neurology 1997;48:626-632.
34. Castle NG, Mor V: Hospitalization of nursing home residents: A review of the literature, 1980-1995. Med Care Res Rev 1996;53:123-148.
35. Gillick M, Steel K: Referral of patients from long term to acute care facilities. J Am Geriatr Soc 1983;31:74-78.
36. Gabow PA, Hutt DM, Baker S, Craig SR, Gordon JB, Lezotte DC: Comparison of hospitalization between nursing home and community residents. J Am Geriatr Soc 1985;33:524-529.
37. Fried TR, Mor V: Frailty and hospitalization of long-term stay nursing home residents. J Am Geriatr Soc 1997;45:265-269.
38. Intrator O, Castle NG, Mor V: Determinants of hospitalization among nursing home residents: Results of a national study. Med Care, in press.
39. Campbell AJ, Diep C, Reinken J, McCosh L: Factors predicting mortality in a total population sample of the elderly. J Epidemiol Community Health 1985;39:337-342.
40. Kelman HR, Thomas C, Kennedy GJ, Cheng J: Cognitive impairment and mortality in older community residents. Am J Public Health 1994;84:1255-1260.
41. Guo Z, Viitanen M, Winblad B: Low blood pressure and five-year mortality in a Stockholm cohort of the very old: Possible confounding by cognitive impairment and other factors. Am J Public Health 1997;87:623-628.
42. Perls TT, Morris JN, Ooi WL, Lipsitz LA: The relationship between age, gender and cognitive performance in the very old: The effect of selective survival. J Am Geriatr Soc 1993;41: 1193-1201.
43. Vitaliano PP, Peck A, Johnson DA, Prinz PN, Eisdorfer C: Dementia and other competing risks for mortality in the institutionalized aged. J Am Geriatr Soc 1981;29:513-519.
44. Barclay LL, Zemcov A, Blass JP, Sansone J: Survival in Alzheimer's disease and vascular dementias. Neurology 1985;35:834-840.
45. Knopman DS, Kitto J, Deinard S, Heiring J: Longitudinal study of death and institutionalization in patients with primary degenerative dementia. J Am Geriatr Soc 1988;36:108-112.
46. Molsa PK, Marttila RJ, Rinne UK: Survival and cause of death in Alzheimer's disease and multi-infarct dementia. Acta Neurol Scand 1986;74:103-107.
47. Evans DA, Smith LA, Scherr PA, Albert MS, Funkenstein HH, Hebert LE: Risk of death from Alzheimer's disease in a community population of older persons. Am J Epidemiol 1991; 134:403-412.
48. Teresi J, Lawton MP, Ory M, Holmes D: Assessment issues in chronic care populations: Dementia special care. Alzheimer Dis Assoc Disord 1994;8:S144-S183.
49. Bowler JV, Munoz DG, Merskey H, Hachinski V: Fallacies in the pathological confirmation of the diagnosis of Alzheimer's disease. J Neurol Neurosurg Psychiatry 1998;64:18-24.
50. Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Markesbery WR: Brain infarction and the clinical expression of Alzheimer disease: The Nun Study. JAMA 1997;277: 813-817.
51. Brayne C, Gill C, Huppert FA, Barkley C, Gehlhaar E, Girling DM, O'Connor DW, Paykel ES: Vascular risks and incident dementia: Results from a cohort study of the very old. Dement Geriatr Cogn Disord 1998;9:175-180.
52. Rockwood K: Lessons from mixed dementia. Int Psychogeriatr 1997;9:245-149.
53. Skoog I, Nilsson L, Palmertz B, Andreasson LA, Svanborg A: A population-based study of dementia in 85 year-olds. N Engl J Med 1993; 328:153-158.
54. Siennicki-Lantz A, Lilja B, Rosen I, Elmstahl S: Cerebral blood flow in white matter is correlated with systolic blood pressure and EEG in senile dementia of the Alzheimer type. Dement Geriatr Cogn Disord 1998;9:29-38.
55. Ott BR, Faberman RS, Noto RB, Rogg JM, Hough TJ, Tung GA, Spencer PK: A SPECT imaging study of MRI white matter hyperintensity in patients with degenerative dementia. Dement Geriatr Cogn Disord 1997;8:348-354.
56. Wang SY, Fukagawa N, Hossain M, Ooi WL: Longitudinal weight changes, length of survival, and energy requirements of long-term care residents with dementia. J Am Geriatr Soc 1997;45:1189-1195.