메뉴 건너뛰기




Volumn 224, Issue 1-2, 1999, Pages 89-99

Mapping of the minimal domain encoding a conformational epitope by λ phage surface display: Factor VIII inhibitor antibodies from haemophilia A patients

Author keywords

Affinity selection; Bacteriophage ; Fusion protein; Surface expression

Indexed keywords

BLOOD CLOTTING FACTOR 8 INHIBITOR; HYBRID PROTEIN;

EID: 0033056797     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(99)00012-5     Document Type: Article
Times cited : (28)

References (58)
  • 1
    • 0022519337 scopus 로고
    • Three-dimensional structure of an antigen-antibody complex at 2.8 Å resolution
    • Amit A.G., Mariuzza R.A., Phillips S.E.V., Poljak R.J. Three-dimensional structure of an antigen-antibody complex at 2.8 Å resolution. Science. 233:1986;747.
    • (1986) Science , vol.233 , pp. 747
    • Amit, A.G.1    Mariuzza, R.A.2    Phillips, S.E.V.3    Poljak, R.J.4
  • 2
    • 0024328077 scopus 로고
    • Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid
    • Arai M., Scandella D., Hoyer L.W. Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid. J. Clin. Invest. 83:1989;1978.
    • (1989) J. Clin. Invest. , vol.83 , pp. 1978
    • Arai, M.1    Scandella, D.2    Hoyer, L.W.3
  • 8
    • 0027739665 scopus 로고
    • Mutations that allow disulfide bond formation in the cytoplasm of Escherichia coli
    • Derman A.I., Prinz W.A., Belin D., Beckwith J. Mutations that allow disulfide bond formation in the cytoplasm of Escherichia coli. Science. 262:1993;1744.
    • (1993) Science , vol.262 , pp. 1744
    • Derman, A.I.1    Prinz, W.A.2    Belin, D.3    Beckwith, J.4
  • 9
    • 0029022722 scopus 로고
    • Assembly of functional bacteriophage lambda virions incorporating C-terminal peptide or protein fusions with the major tail protein
    • Dunn I.S. Assembly of functional bacteriophage lambda virions incorporating C-terminal peptide or protein fusions with the major tail protein. J. Mol. Biol. 248:1995;497.
    • (1995) J. Mol. Biol. , vol.248 , pp. 497
    • Dunn, I.S.1
  • 11
    • 0015116634 scopus 로고
    • Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G.
    • Engvall E., Perlmann P. Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. Immunochemistry. 8:1971;871.
    • (1971) Immunochemistry , vol.8 , pp. 871
    • Engvall, E.1    Perlmann, P.2
  • 13
    • 0025923490 scopus 로고
    • Human factor VIIIa subunit structure. Reconstitution of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit
    • Fay P.J., Haidaris P.J., Smudzin T.M. Human factor VIIIa subunit structure. Reconstitution of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit. J. Biol. Chem. 266:1991;8957.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8957
    • Fay, P.J.1    Haidaris, P.J.2    Smudzin, T.M.3
  • 16
    • 0025297357 scopus 로고
    • Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine
    • Foster P.A., Fulcher C.A., Houghten R.A., Zimmerman T.S. Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine. Blood. 75:1990;1999.
    • (1990) Blood , vol.75 , pp. 1999
    • Foster, P.A.1    Fulcher, C.A.2    Houghten, R.A.3    Zimmerman, T.S.4
  • 17
    • 0023274159 scopus 로고
    • FVIII inhibitor IgG subclass and FVIII polypeptide specificity determined by immunoblotting
    • Fulcher C.A., de Graaf Mahoney S., Zimmerman T.S. FVIII inhibitor IgG subclass and FVIII polypeptide specificity determined by immunoblotting. Blood. 69:1987;1475.
    • (1987) Blood , vol.69 , pp. 1475
    • Fulcher, C.A.1    De Graaf Mahoney, S.2    Zimmerman, T.S.3
  • 19
    • 0029030435 scopus 로고
    • Residues 484-508 contain a major determinant of the inhibitory epitope in the A2 domain of human factor VIII
    • Healey J.F., Lubin I.M., Nakai H., Saenko E.L., Hoyer L.W., Scandella D., Lollar P. Residues 484-508 contain a major determinant of the inhibitory epitope in the A2 domain of human factor VIII. J. Biol. Chem. 270:1995;14505.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14505
    • Healey, J.F.1    Lubin, I.M.2    Nakai, H.3    Saenko, E.L.4    Hoyer, L.W.5    Scandella, D.6    Lollar, P.7
  • 20
    • 0031588015 scopus 로고    scopus 로고
    • Epitope mapping by negative selection of randomized antigen libraries displayed on filamentous phage
    • Jespers L., Jenné S., Lasters I., Collen D. Epitope mapping by negative selection of randomized antigen libraries displayed on filamentous phage. J. Mol. Biol. 269:1997;704.
    • (1997) J. Mol. Biol. , vol.269 , pp. 704
    • Jespers, L.1    Jenné, S.2    Lasters, I.3    Collen, D.4
  • 21
    • 0026675750 scopus 로고
    • High resolution functional analysis of antibody-antigen interactions
    • Jin L., Fendly B.M., Wells J.A. High resolution functional analysis of antibody-antigen interactions. J. Mol. Biol. 226:1992;851.
    • (1992) J. Mol. Biol. , vol.226 , pp. 851
    • Jin, L.1    Fendly, B.M.2    Wells, J.A.3
  • 24
    • 0030807719 scopus 로고    scopus 로고
    • Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis
    • Lubin I.M., Healey J.F., Barrow R.T., Scandella D., Lollar P. Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis. J. Biol. Chem. 272:1997;30191.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30191
    • Lubin, I.M.1    Healey, J.F.2    Barrow, R.T.3    Scandella, D.4    Lollar, P.5
  • 25
    • 0027158405 scopus 로고
    • Mimicking of discontinuous epitopes by phage-displayed peptides: I. Epitope mapping of human H ferritin using a phage library of constrained peptides
    • Luzzago A., Felici F., Tramontano A., Pessi A., Cortese R. Mimicking of discontinuous epitopes by phage-displayed peptides: I. Epitope mapping of human H ferritin using a phage library of constrained peptides. Gene. 128:1993;51.
    • (1993) Gene , vol.128 , pp. 51
    • Luzzago, A.1    Felici, F.2    Tramontano, A.3    Pessi, A.4    Cortese, R.5
  • 26
    • 0030570513 scopus 로고    scopus 로고
    • Role of capsid structure and membrane protein processing in determining the size and copy number of peptides displayed on the major coat protein of filamentous bacteriophage
    • Malik P., Terry T.D., Gowda L.R., Langara A., Petukhov S.A., Symmons M.F., Welsh L.C., Marvin D.A., Perham R.N. Role of capsid structure and membrane protein processing in determining the size and copy number of peptides displayed on the major coat protein of filamentous bacteriophage. J. Mol. Biol. 260:1996;9.
    • (1996) J. Mol. Biol. , vol.260 , pp. 9
    • Malik, P.1    Terry, T.D.2    Gowda, L.R.3    Langara, A.4    Petukhov, S.A.5    Symmons, M.F.6    Welsh, L.C.7    Marvin, D.A.8    Perham, R.N.9
  • 28
    • 0028845410 scopus 로고
    • A model for transmembrane signalling by the aspartate receptor based on random-cassette mutagenesis and site-directed disulfide cross-linking
    • Maruyama I.N., Mikawa Y.G., Maruyama H.I. A model for transmembrane signalling by the aspartate receptor based on random-cassette mutagenesis and site-directed disulfide cross-linking. J. Mol. Biol. 253:1995;530.
    • (1995) J. Mol. Biol. , vol.253 , pp. 530
    • Maruyama, I.N.1    Mikawa, Y.G.2    Maruyama, H.I.3
  • 29
    • 0028939696 scopus 로고
    • Locations of disulfide bonds and free cysteines in the heavy and light chains of recombinant human factor VIII (antihemophilic factor A)
    • McMullen B.A., Fujikawa K., Davie E.W., Hedner U., Ezban M. Locations of disulfide bonds and free cysteines in the heavy and light chains of recombinant human factor VIII (antihemophilic factor A). Protein Sci. 4:1995;740.
    • (1995) Protein Sci. , vol.4 , pp. 740
    • McMullen, B.A.1    Fujikawa, K.2    Davie, E.W.3    Hedner, U.4    Ezban, M.5
  • 31
    • 0030582396 scopus 로고    scopus 로고
    • Surface display of proteins on bacteriophage lambda heads
    • Mikawa Y.G., Maruyama I.N., Brenner S. Surface display of proteins on bacteriophage lambda heads. J. Mol. Biol. 262:1996;21.
    • (1996) J. Mol. Biol. , vol.262 , pp. 21
    • Mikawa, Y.G.1    Maruyama, I.N.2    Brenner, S.3
  • 32
    • 0025142485 scopus 로고
    • An antibody binding site on cytochrome c defined by hydrogen exchange and two-dimensional NMR
    • Paterson Y., Englander S.W., Roder H. An antibody binding site on cytochrome c defined by hydrogen exchange and two-dimensional NMR. Science. 249:1990;755.
    • (1990) Science , vol.249 , pp. 755
    • Paterson, Y.1    Englander, S.W.2    Roder, H.3
  • 33
    • 0029588523 scopus 로고
    • Mapping of linear epitopes recognized by monoclonal antibodies with gene-fragment phage display libraries
    • Petersen G., Song D., Hügle-Dörr B., Oldenburg I., Bautz E.K.F. Mapping of linear epitopes recognized by monoclonal antibodies with gene-fragment phage display libraries. Mol. Gen. Genet. 249:1995;425.
    • (1995) Mol. Gen. Genet. , vol.249 , pp. 425
    • Petersen, G.1    Song, D.2    Hügle-Dörr, B.3    Oldenburg, I.4    Bautz, E.K.F.5
  • 34
    • 0030329982 scopus 로고    scopus 로고
    • Tea bag synthesis of positional scanning synthetic combinatorial libraries and their use for mapping antigenic determinants
    • Pinilla C., Appel J.R., Houghten R.A. Tea bag synthesis of positional scanning synthetic combinatorial libraries and their use for mapping antigenic determinants. Methods Mol. Biol. 66:1996;171.
    • (1996) Methods Mol. Biol. , vol.66 , pp. 171
    • Pinilla, C.1    Appel, J.R.2    Houghten, R.A.3
  • 36
    • 0029032377 scopus 로고
    • A mechanism for inhibition of factor VIII binding to phospholipid by von Willebrand factor
    • Saenko E.L., Scandella D. A mechanism for inhibition of factor VIII binding to phospholipid by von Willebrand factor. J. Biol. Chem. 270:1995;13826.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13826
    • Saenko, E.L.1    Scandella, D.2
  • 37
    • 0030800963 scopus 로고    scopus 로고
    • The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von Willebrand factor
    • Saenko E.L., Scandella D. The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von Willebrand factor. J. Biol. Chem. 272:1997;18007.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18007
    • Saenko, E.L.1    Scandella, D.2
  • 40
    • 0032508462 scopus 로고    scopus 로고
    • Efficient display of an HCV cDNA expression library as C-terminal fusion to the capsid protein D of bacteriophage lambda
    • Santini C., Brennan D., Mennuni C., Hoess R.H., Nicosia A., Cortese R., Luzzago A. Efficient display of an HCV cDNA expression library as C-terminal fusion to the capsid protein D of bacteriophage lambda. J. Mol. Biol. 282:1998;125.
    • (1998) J. Mol. Biol. , vol.282 , pp. 125
    • Santini, C.1    Brennan, D.2    Mennuni, C.3    Hoess, R.H.4    Nicosia, A.5    Cortese, R.6    Luzzago, A.7
  • 41
    • 0024451521 scopus 로고
    • Localization of epitopes for human factor VIII inhibitor antibodies by immunoblotting and antibody neutralization
    • Scandella D., Mattingly M., de Graaf S., Fulcher C.A. Localization of epitopes for human factor VIII inhibitor antibodies by immunoblotting and antibody neutralization. Blood. 74:1989;1618.
    • (1989) Blood , vol.74 , pp. 1618
    • Scandella, D.1    Mattingly, M.2    De Graaf, S.3    Fulcher, C.A.4
  • 42
    • 0026720912 scopus 로고
    • A soluble recombinant factor VIII fragment containing the A2 domain binds to some human anti-factor VIII antibodies that are not detected by immunoblotting
    • Scandella D., Timmons L., Mattingly M., Trabold N., Hoyer L.W. A soluble recombinant factor VIII fragment containing the A2 domain binds to some human anti-factor VIII antibodies that are not detected by immunoblotting. Thromb. Haemost. 67:1992;665.
    • (1992) Thromb. Haemost. , vol.67 , pp. 665
    • Scandella, D.1    Timmons, L.2    Mattingly, M.3    Trabold, N.4    Hoyer, L.W.5
  • 43
    • 0029154988 scopus 로고
    • Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site
    • Scandella D., Gilbert G.E., Shima M., Nakai H., Eagleson C., Felch M., Prescott R., Rajalakshmi K.J., Hoyer L.W., Saenko E. Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site. Blood. 86:1995;1811.
    • (1995) Blood , vol.86 , pp. 1811
    • Scandella, D.1    Gilbert, G.E.2    Shima, M.3    Nakai, H.4    Eagleson, C.5    Felch, M.6    Prescott, R.7    Rajalakshmi, K.J.8    Hoyer, L.W.9    Saenko, E.10
  • 44
    • 0025112794 scopus 로고
    • Searching for peptide ligands with an epitope library
    • Scott J.K., Smith G.P. Searching for peptide ligands with an epitope library. Science. 249:1990;386.
    • (1990) Science , vol.249 , pp. 386
    • Scott, J.K.1    Smith, G.P.2
  • 45
    • 0027457180 scopus 로고
    • A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine
    • Shima M., Scandella D., Yoshioka A., Nakai H., Tanaka I., Kamisue S., Terada S., Fukui H. A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine. Thromb. Haemost. 69:1993;240.
    • (1993) Thromb. Haemost. , vol.69 , pp. 240
    • Shima, M.1    Scandella, D.2    Yoshioka, A.3    Nakai, H.4    Tanaka, I.5    Kamisue, S.6    Terada, S.7    Fukui, H.8
  • 47
    • 0028907327 scopus 로고
    • Display of peptides and proteins on the surface of bacteriophage λ
    • Sternberg N., Hoess R.H. Display of peptides and proteins on the surface of bacteriophage λ Proc. Natl. Acad. Sci. U.S.A. 92:1995;1609.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 1609
    • Sternberg, N.1    Hoess, R.H.2
  • 48
    • 0026538591 scopus 로고
    • Characterization of a factor VIII immunogenic site using factor VIII synthetic peptide 1687-1695 and rabbit anti-peptide antibodies
    • Tiarks C., Pechet L., Anderson J., Mole J.E., Humphreys R.E. Characterization of a factor VIII immunogenic site using factor VIII synthetic peptide 1687-1695 and rabbit anti-peptide antibodies. Thromb. Res. 65:1992;301.
    • (1992) Thromb. Res. , vol.65 , pp. 301
    • Tiarks, C.1    Pechet, L.2    Anderson, J.3    Mole, J.E.4    Humphreys, R.E.5
  • 50
    • 0019831499 scopus 로고
    • The role of phospholipid and factor VIIIa in the activation of bovine factor X
    • van Dieijen G., Tans G., Rosing J., Hemker H.C. The role of phospholipid and factor VIIIa in the activation of bovine factor X. J. Biol. Chem. 256:1981;3433.
    • (1981) J. Biol. Chem. , vol.256 , pp. 3433
    • Van Dieijen, G.1    Tans, G.2    Rosing, J.3    Hemker, H.C.4
  • 51
    • 0029584350 scopus 로고
    • Identification of functional interaction sites on proteins using bacteriophage-displayed random epitope libraries
    • van Zonneveld A.-J., van den Berg B.M.M., van Meijer M., Pannekoek H. Identification of functional interaction sites on proteins using bacteriophage-displayed random epitope libraries. Gene. 167:1995;49.
    • (1995) Gene , vol.167 , pp. 49
    • Van Zonneveld, A.-J.1    Van Den Berg, B.M.M.2    Van Meijer, M.3    Pannekoek, H.4
  • 53
    • 0028801675 scopus 로고
    • Use of a gene-targeted phage display random epitope library to map an antigenic determinant on the bluetongue virus outer capsid protein VP5
    • Wang L.-F., Plessis D.H.D., White J.R., Hyatt A.D., Eaton B.T. Use of a gene-targeted phage display random epitope library to map an antigenic determinant on the bluetongue virus outer capsid protein VP5. J. Immunol. Methods. 178:1995;1.
    • (1995) J. Immunol. Methods , vol.178 , pp. 1
    • Wang, L.-F.1    Plessis, D.H.D.2    White, J.R.3    Hyatt, A.D.4    Eaton, B.T.5
  • 54
    • 0027050152 scopus 로고
    • Epitope mapping of human factor VIII inhibitor antibodies by site-directed mutagenesis of a factor VIII polypeptide
    • Ware J., MacDonald M.J., Lo M., de Graaf S., Fulcher C.A. Epitope mapping of human factor VIII inhibitor antibodies by site-directed mutagenesis of a factor VIII polypeptide. Blood Coagul. Fibrinolysis. 3:1992;703.
    • (1992) Blood Coagul. Fibrinolysis , vol.3 , pp. 703
    • Ware, J.1    MacDonald, M.J.2    Lo, M.3    De Graaf, S.4    Fulcher, C.A.5
  • 56
    • 0021943518 scopus 로고
    • Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors
    • Yanisch-Perron C., Vieira J., Messing J. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene. 33:1985;103.
    • (1985) Gene , vol.33 , pp. 103
    • Yanisch-Perron, C.1    Vieira, J.2    Messing, J.3
  • 57
    • 0032127414 scopus 로고    scopus 로고
    • Some human inhibitor antibodies interfere with factor VIII binding to factor IX
    • Zhong D., Saenko E.L., Shima M., Felch M., Scandella D. Some human inhibitor antibodies interfere with factor VIII binding to factor IX. Blood. 92:1998;136.
    • (1998) Blood , vol.92 , pp. 136
    • Zhong, D.1    Saenko, E.L.2    Shima, M.3    Felch, M.4    Scandella, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.