The canine factor VIII cDNA and 5' flanking sequence

Thrombosis and Haemostasis

Volumn 79, Issue 2, 1998, Pages 317-322

  Cameron, Cherie ^a   Notley, Colleen ^a   Hoyle, Susan ^a   McGlynn, Leslie ^a   Hough, Christine ^a   Kamisue, Seiki ^a   Giles, Alan ^a   Lillicrap, David ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; COMPLEMENTARY DNA; THROMBIN; TRANSCRIPTION FACTOR; TYROSINE; VON WILLEBRAND FACTOR;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING SITE; DOG; GENE SEQUENCE; GENE THERAPY; HEMOPHILIA A; HUMAN; MOUSE; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEQUENCE HOMOLOGY; SULFATION; SWINE;

EID: 0031884476     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1614984     Document Type: Article

References (29)

1. Hoyer LW. Hemophilia A. N Engl J Med 1994; 330: 38-47.
2. Wion, Kelly D, Summerfield JA, Tuddenham EGD, Lawn RM. Distribution of factor VIII mRNA and antigen in human liver and other tissues. Nature 1985; 317: 726-8.
3. Wood WI, Capon DJ, Siinonsen CC, Eaton DL, Gitschier J, Keyt B, Seeburg PH, Smith DH, Hollingshead P, Wion KH, Delwart E, Tuddenham EGD, Vehar GA, Lawn RM. Expression of active human factor VIII from recombinant DNA clones. Nature 1984; 312: 330-6.
4. Pass DN, Hewick RM, Knutson GJ, Nesheim ME, Mann KG. Internal duplication and sequence homology in factors V and VIII. Proc Natl Acad Sci USA 1985;82: 1688-91.
5. Church WR, Jernigan RL, Toole J, Hewick RM, Knopf J, Knutson GJ, Nesheim ME, Mann KG, Fass DN. Coagulation factors V and VIII and ceruloplasmin constitute a family of structurally related proteins. Proc Natl Acad Sci USA 1984; 81: 6934-7.
6. Pittman DD, Kaufrnan RJ. Structure-function relationships of factor VIII elucidated through recombinant DNA technology. Thromb Haemost 1989; 61: 161-5.
7. Pittman DD, Alderman EM, Tomkinson KN, Wang JH, Giles AR, Kaufman RJ. Biochemical, immunological, and in vivo functional characterization of B-domain-deleted factor VIII. Blood 1993; 81: 2925-35.
8. Hoyer LW. The factor VIII complex: structure and function. Blood 1981; 58: 1-13.
9. Fay PJ, Smudzin TM. Topography of the human factor VIII-von Willebrand factor complex. J Biol Chem 1990; 265: 6197-202.
10. Fay PJ, Walker FJ. Inactivation of human factor VIII by activated protein C: Evidence that the factor VIII light chain contains the activated protein C binding site. Biochim Biophys Acta 1989; 994: 142-8.
11. Gitschier J, Wood WI, Goralka TM, Wion KL, Chen EY, Eaton DH, Vehar GA, Capon DJ, Lawn RM. Characterisation of the human factor VIII gene. Nature 1984:312:326-30.
12. Toole JJ, Knopf JL, Wozney JM, Sultzman LA, Buecker JL, Pittman DD, Kaufman RJ, Brown E, Shoemaker C, Orr C, Amphlett GW, Foster WB, Coe ML, Knutson GJ, Pass DN, Hewick RM. Molecular cloning of cDNA encoding for human antihemophilic factor. Nature 1984; 312: 342-7.
13. Elder B, Lakich D, Gitschier J. Sequence of the murine factor VIII cDNA. Genomics 1993; 16:374-9.
14. Healey JF, Lubin IM, Lollar P. The cDNA and derived amino acid sequence of porcine factor VIII. Blood 1996; 88: 4209-14.
15. Lahiri DK, Nurnberger JI. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 1991 ; 19: 5444.
16. McGlynn LK, Mueller CR, Begbie M, Notley CR, Lillicrap D. Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the factor VIII gene. Mol Cell Biol 1996; 16: 1936-45.
17. Pass DN. Factor VIII structure and function. Ann NY Acad Sci 1991: 614: 76-88.
18. Smale ST, Baltimore D. The »Initiator« as a transcription control element. Cell 1989; 57: 103-13.
19. Figueiredo MS, Brownlee GG. cis-acting elements and transcription factors involved in the promoter activity of the human factor VIII gene. J Biol Chem 1995; 270: 11828-38.
20. Toole JJ, Pittman DD, Orr EC, Murtha P, Wasley LC, Kaufman RJ. A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity. Proc Natl Acad Sci USA 1986:83:5939-42.
21. Lollar P, Parker ET, Fay PJ. Coagulant properties of hybrid human/porcine factor VIII molecules. J Biol Chem 1992; 267: 23652-7.
22. Lollar P, Parker ET. Structural basis for the decreased procoagulant activity of human factor VIII compared to the porcine homolog. J Biol Chem 1991; 266: 12481-6.
23. Bi L, Lawler AM, Antonarakis SE, High KA, Gearhart JD, Kazazian HH Jr. Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A. Nat Genet 1995; 10: 119-21.
24. Giles AR, Tinlin S, Greenwood R. A canine model of hemophilic (Factor VIII:C deficiency) bleeding. Blood 1982: 60: 727-32.
25. Giles AR, Tinlin S, Hoogendoorn H, Fournel MA, Ng P, Pancham N. In vivo characterization of recombinant Factor VIII in a canine model of hemophilia A (Factor VIII deficiency). Blood 1988: 72: 335-9.
26. Bowie EJW, Owen CAJ, Giles AR. Animal models for the study of factor VIII and von Willebrand factor. In : Coagulation and bleeding disorders: the role of factor VIII and von Willebrand factor. Zimmernian TS, Ruggeri ZM, eds. Marcel Dekker, Inc. New York, NY. 1989; pp 305-24.
27. Mertens K, Briët E, Giles AR. The role of factor VII in haemostasis: Infusion studies of factor Vila in a canine model of factor VIII deficiency. Thromb Haemost 1990; 64: 138-44.
28. Tinlin S, Webster S, Giles AR. The development of homologous (canine/anti-canine) antibodies in dogs with haemophilia A (factor VIII deficiency): A ten-year longitudinal study. Thromb Haemost 1993; 69: 21-4.
29. Connelly S, Mount J, Mauser A, Gardner JM, Kaleko M, McClelland A, Lothrop CD Jr. Complete short-term correction of canine hemophilia A by in-vivo gene therapy.