-
1
-
-
0031905861
-
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1 and VEGF receptor 3 (Flt 4)
-
Achen MG, Jeltsch M, Kukk E, Makinen T, Vitali A, Wilks AF, Alitalo K, Stacker SA (1998) Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt 4). Proc Natl Acad Sci USA 95:548-553
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 548-553
-
-
Achen, M.G.1
Jeltsch, M.2
Kukk, E.3
Makinen, T.4
Vitali, A.5
Wilks, A.F.6
Alitalo, K.7
Stacker, S.A.8
-
3
-
-
0031805836
-
An anti-human VEGF monoclonal antibody. MV833, that exhibits potent anti-tumor activity in vivo
-
Asano M, Yukita A, Matsumoto T, Hanatani M, Suzuki H (1998) An anti-human VEGF monoclonal antibody. MV833, that exhibits potent anti-tumor activity in vivo. Hybridoma 17:185-190
-
(1998)
Hybridoma
, vol.17
, pp. 185-190
-
-
Asano, M.1
Yukita, A.2
Matsumoto, T.3
Hanatani, M.4
Suzuki, H.5
-
4
-
-
0029816983
-
Complete inhibition of angiogenesis and growth of microtumors by antivascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy
-
Borgström P, Hillan KJ, Srimararao P, Ferrara N (1996) Complete inhibition of angiogenesis and growth of microtumors by antivascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res 56:4032-4039
-
(1996)
Cancer Res
, vol.56
, pp. 4032-4039
-
-
Borgström, P.1
Hillan, K.J.2
Srimararao, P.3
Ferrara, N.4
-
5
-
-
0029782859
-
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
-
Cheng S-Y, Su Huang H-J, Nagane M, Ji X-D, Wang D, Shih CC-Y, Arap W, Huang CM, Cavenee WK (1996) Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc Natl Acad Sci USA 93:8502-8507
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8502-8507
-
-
Cheng, S.-Y.1
Su Huang, H.-J.2
Nagane, M.3
Ji, X.-D.4
Wang, D.5
Shih, C.-Y.6
Arap, W.7
Huang, C.M.8
Cavenee, W.K.9
-
6
-
-
0026572345
-
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
-
De Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT (1992) The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:989-991
-
(1992)
Science
, vol.255
, pp. 989-991
-
-
De Vries, C.1
Escobedo, J.A.2
Ueno, H.3
Houck, K.4
Ferrara, N.5
Williams, L.T.6
-
7
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak HF, Brown LF, Detmar M, Dvorak AM (1995) Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 146:1029-1039
-
(1995)
Am J Pathol
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
8
-
-
0344109584
-
Markers of tumor angiogenesis and proteolysis (VEGF, uPA) independently define high-and low-risk subsets of node-negative breast cancer patients
-
Eppenberger U, Kueng W, Schlaeppi J-M, Roesel JL, Benz C, Mueller H, Matter A, Zuber M, Luescher K, Litschgi M, Schmitt M, Foekens JA, Eppenberger-Castori S (1998) Markers of tumor angiogenesis and proteolysis (VEGF, uPA) independently define high-and low-risk subsets of node-negative breast cancer patients. J Clin Oncol 16:3129-3136
-
(1998)
J Clin Oncol
, vol.16
, pp. 3129-3136
-
-
Eppenberger, U.1
Kueng, W.2
Schlaeppi, J.-M.3
Roesel, J.L.4
Benz, C.5
Mueller, H.6
Matter, A.7
Zuber, M.8
Luescher, K.9
Litschgi, M.10
Schmitt, M.11
Foekens, J.A.12
Eppenberger-Castori, S.13
-
9
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
Ferrara N, Davis-Smyth T (1997) The biology of vascular endothelial growth factor. Endocrine Rev 18:4-25
-
(1997)
Endocrine Rev
, vol.18
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smyth, T.2
-
10
-
-
0026505773
-
Molecular and biological properties of the vascular endothelial growth factor family of proteins
-
Ferrara N, Houck K, Jakeman L, Leung DW (1992) Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrine Rev 13:18-32
-
(1992)
Endocrine Rev
, vol.13
, pp. 18-32
-
-
Ferrara, N.1
Houck, K.2
Jakeman, L.3
Leung, D.W.4
-
11
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW (1996) Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380:439-442
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
12
-
-
0027533021
-
Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells
-
Fiebich BL, Jäger B, Schöllmann C, Weindel K, Wilting J, Kochs G, Marmé D, Hug H, Weich HA (1993) Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells. Eur J Biochem 211:19-26
-
(1993)
Eur J Biochem
, vol.211
, pp. 19-26
-
-
Fiebich, B.L.1
Jäger, B.2
Schöllmann, C.3
Weindel, K.4
Wilting, J.5
Kochs, G.6
Marmé, D.7
Hug, H.8
Weich, H.A.9
-
13
-
-
0026846928
-
The role of angiogenesis in tumor growth
-
Folkman J (1992) The role of angiogenesis in tumor growth. Semin Cancer Biol 3:66-71
-
(1992)
Semin Cancer Biol
, vol.3
, pp. 66-71
-
-
Folkman, J.1
-
14
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease, Nature Med 1:27-31
-
(1995)
Nature Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
16
-
-
0342813129
-
Experimental design for kinetic analysis of protein-protein interactions with surface plasmon resonance biosensors
-
Karlsson R, Fält A (1997) Experimental design for kinetic analysis of protein-protein interactions with surface plasmon resonance biosensors. J Immunol Methods 200:121-133
-
(1997)
J Immunol Methods
, vol.200
, pp. 121-133
-
-
Karlsson, R.1
Fält, A.2
-
17
-
-
0029920944
-
Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis
-
Keyt BA, Nguyen HV, Berleau LT, Duarte CM, Park J, Chen H, Ferrara N (1996) Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis. J Biol Chem 271:5638-5646
-
(1996)
J Biol Chem
, vol.271
, pp. 5638-5646
-
-
Keyt, B.A.1
Nguyen, H.V.2
Berleau, L.T.3
Duarte, C.M.4
Park, J.5
Chen, H.6
Ferrara, N.7
-
18
-
-
0026708632
-
The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies
-
Kim KJ, Li B, Houck K, Winer J, Ferrara N (1992) The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors 7:53-64
-
(1992)
Growth Factors
, vol.7
, pp. 53-64
-
-
Kim, K.J.1
Li, B.2
Houck, K.3
Winer, J.4
Ferrara, N.5
-
19
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362:841-844
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
20
-
-
0031671095
-
Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma
-
Linderholm B, Tavelin B, Grankvist K, Henriksson R (1998) Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma. J Clin Oncol 16:3121-3128
-
(1998)
J Clin Oncol
, vol.16
, pp. 3121-3128
-
-
Linderholm, B.1
Tavelin, B.2
Grankvist, K.3
Henriksson, R.4
-
21
-
-
0030066037
-
Prognostic value of vascular endothelial growth factor expression in gastric carcinoma
-
Maeda K, Chung Y-S, Ogawa Y, Takatsuka S, Kang S-M, Ogawa M, Sawada T, Sowa M (1996) Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer 77:858-863
-
(1996)
Cancer
, vol.77
, pp. 858-863
-
-
Maeda, K.1
Chung, Y.-S.2
Ogawa, Y.3
Takatsuka, S.4
Kang, S.-M.5
Ogawa, M.6
Sawada, T.7
Sowa, M.8
-
22
-
-
0026052391
-
Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor
-
Maglione D, Guerriero V, Viglietto G, Delli-Bovi P, Persico MG (1991) Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc Natl Acad Sci USA 88:9267-9271
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 9267-9271
-
-
Maglione, D.1
Guerriero, V.2
Viglietto, G.3
Delli-Bovi, P.4
Persico, M.G.5
-
23
-
-
0028174337
-
Glioblastoma growth inhibited in vivo by a dominant-negative FlK-1 mutant
-
Millauer B, Shawver LK, Plate KH, Risau W, Ullrich A (1994) Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367:576-578
-
(1994)
Nature
, vol.367
, pp. 576-578
-
-
Millauer, B.1
Shawver, L.K.2
Plate, K.H.3
Risau, W.4
Ullrich, A.5
-
24
-
-
0030795733
-
Vascular endothelial growth factor: Crystal structure and functional mapping of the kinase domain receptor binding site
-
Muller YA, Li B, Christinger HW, Wells JA, Cunningham BC, De Vos AM (1997a) Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site. Proc Natl Acad Sci USA 94:7192-7197
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7192-7197
-
-
Muller, Y.A.1
Li, B.2
Christinger, H.W.3
Wells, J.A.4
Cunningham, B.C.5
De Vos, A.M.6
-
25
-
-
0031572858
-
The crystal structure of vascular endothelial growth factor (VEFG) to 1.93 Å resolution: Multiple copy flexibility and receptor binding
-
Muller YA, Christinger HW, Keyt BA, De Vos AM (1997b) The crystal structure of vascular endothelial growth factor (VEFG) to 1.93 Å resolution: multiple copy flexibility and receptor binding. Structure 5:1325-1338
-
(1997)
Structure
, vol.5
, pp. 1325-1338
-
-
Muller, Y.A.1
Christinger, H.W.2
Keyt, B.A.3
De Vos, A.M.4
-
26
-
-
0030923795
-
Vascular endothelial growth factor expression in early stage ovarian carcinoma
-
Paley PJ, Staskus KA, Gebhard K, Mohanraj D, Twiggs LB, Carson LF, Ramakrishnan S (1997) Vascular endothelial growth factor expression in early stage ovarian carcinoma. Cancer 80:98-106
-
(1997)
Cancer
, vol.80
, pp. 98-106
-
-
Paley, P.J.1
Staskus, K.A.2
Gebhard, K.3
Mohanraj, D.4
Twiggs, L.B.5
Carson, L.F.6
Ramakrishnan, S.7
-
27
-
-
0030029271
-
Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence
-
Saleh M, Stacker SA, Wilks AF (1996) Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence. Cancer Res 56:393-401
-
(1996)
Cancer Res
, vol.56
, pp. 393-401
-
-
Saleh, M.1
Stacker, S.A.2
Wilks, A.F.3
-
28
-
-
0029801959
-
Chemiluminescence immunoassay for vascular endothelial growth factor (vascular permeability factor) in tumor-tissue homogenates
-
Schlaeppi J-M, Eppenberger U, Martiny-Baron G, Küng W (1996) Chemiluminescence immunoassay for vascular endothelial growth factor (vascular permeability factor) in tumor-tissue homogenates. Clin Chem 42:1777-1784
-
(1996)
Clin Chem
, vol.42
, pp. 1777-1784
-
-
Schlaeppi, J.-M.1
Eppenberger, U.2
Martiny-Baron, G.3
Küng, W.4
-
29
-
-
0032515980
-
An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells
-
Siemeister G, Schirner M, Reusch P, Barleon B, Marmé D, Martiny-Baron G (1998a) An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells. Proc Natl Acad Sci USA 95:4625-4629
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4625-4629
-
-
Siemeister, G.1
Schirner, M.2
Reusch, P.3
Barleon, B.4
Marmé, D.5
Martiny-Baron, G.6
-
30
-
-
0032079869
-
The alpha-helical domain near the amino-terminus is essential for dimerization of vascular endothelial growth factor
-
Siemeister G, Marmé D, Martiny-Baron G (1998b) The alpha-helical domain near the amino-terminus is essential for dimerization of vascular endothelial growth factor. J Biol Chem 273:11115-11120
-
(1998)
J Biol Chem
, vol.273
, pp. 11115-11120
-
-
Siemeister, G.1
Marmé, D.2
Martiny-Baron, G.3
-
31
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D, Bohlen P (1992) Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 187:1579-1586
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 1579-1586
-
-
Terman, B.I.1
Dougher-Vermazen, M.2
Carrion, M.E.3
Dimitrov, D.4
Armellino, D.C.5
Gospodarowicz, D.6
Bohlen, P.7
-
32
-
-
0025999033
-
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
-
Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fiddes JC, Abraham JA (1991) The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 266:11947-11954
-
(1991)
J Biol Chem
, vol.266
, pp. 11947-11954
-
-
Tischer, E.1
Mitchell, R.2
Hartman, T.3
Silva, M.4
Gospodarowicz, D.5
Fiddes, J.C.6
Abraham, J.A.7
-
33
-
-
0029143990
-
Tumor angiogenesis in breast cancer: Its importance as a prognostic indicator and the association with vascular endothelial growth factor expression
-
Toi M, Inada K, Suzuki H, Tominaga T (1995) Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression. Breast Cancer Res Treat 36:193-204
-
(1995)
Breast Cancer Res Treat
, vol.36
, pp. 193-204
-
-
Toi, M.1
Inada, K.2
Suzuki, H.3
Tominaga, T.4
-
34
-
-
1842328560
-
Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer
-
Volm M, Koomägi R, Mattern J (1997) Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer. Int J Cancer 74:64-68
-
(1997)
Int J Cancer
, vol.74
, pp. 64-68
-
-
Volm, M.1
Koomägi, R.2
Mattern, J.3
-
35
-
-
0027732212
-
Tumor angiogenesis: Review of current applications in tumor prognostication
-
Weidner N (1993) Tumor angiogenesis: review of current applications in tumor prognostication. Semin Diagnost Path 10:302-313
-
(1993)
Semin Diagnost Path
, vol.10
, pp. 302-313
-
-
Weidner, N.1
-
36
-
-
0030782410
-
Crystal structure at 1.7 Å resolution of VEGF in complex with domain 2 of the Flt-1 receptor
-
Wiesmann C, Fuh G, Christinger HW, Eigenbrot C, Wells JA, De Vos AM (1997) Crystal structure at 1.7 Å resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell 91:695-704
-
(1997)
Cell
, vol.91
, pp. 695-704
-
-
Wiesmann, C.1
Fuh, G.2
Christinger, H.W.3
Eigenbrot, C.4
Wells, J.A.5
De Vos, A.M.6
|