Exposure temperature, but not donor age, is a confounding factor for in vitro translocation production by chronic irradiation

International Journal of Radiation Biology

Volumn 75, Issue 6, 1999, Pages 673-680

  Lucas, J N ^a   Deng, W ^b   Hsieh, W A ^a   Galvan, N ^a   Gale, K L ^c   Morrison, D P ^c  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^b Sichuan Reproductive Health Institute   (China)

^c ATOMIC ENERGY OF CANADA LIMITED   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ARTICLE; CHROMOSOME MUTATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION MUTAGENESIS; TEMPERATURE;

ADULT; AGE FACTORS; AGED; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; RELATIVE BIOLOGICAL EFFECTIVENESS; TEMPERATURE; TRANSLOCATION, GENETIC;

TRITIUM;

EID: 0033053561     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530099140005     Document Type: Article

References (24)

1. Bajerska, A. and Liniecki, J., 1969, The influence of temperature at irradiation in vitro on the yield of chromosomal aberrations in peripheral blood lymphocytes. International Journal of Radiation Biology, 16, 483-493.
2. Bolognesi, C., Abbondandolo, A., Barale, R., Casalone, R., Dalpra, L., De Ferrari, M., Degrassi, F., Forni, A., Lamberti, L., Lando, C., Migliore, L., Padovani, P., Pasquini, R., Puntoni, R., Sbrana, I., Stella, M. and Bonassi, S., 1997, Age-related increase of baseline frequencies of sister chromatid exchanges, chromosome aberrations, and micronuclei in human lymphocytes. Cancer Epidemiology, Biomarkers and Prevention, 6, 249-256.
3. Bovum, A., 1968, Separation of leukocytes from blood and bone marrow. Scandinavian Journal of Clinical Laboratory Investigation, 21, 77.
4. Brewen, J. G. and Preston, R. J., 1973, Chromosome aberrations as a measure of mutagenesis: comparisons in vitro and in vivo and in somatic and germ cells. Environmental Health Perspectives, 6, 157-166.
5. Deng, W., Morrison, D. P., Gale, K. L. and Lucas, J. N., 1998, Biological dosimetry of beta-ray exposure to tritium using chromosome translocations in human lymphocytes analyzed by fluorescence in situ hybridization. Radiation Research, 150, 400-405.
6. Foray, N., Fertil, B., Alsbeih, M. G. A., Badie, C., Chavaudra, N., Iliakis, G. and Malaise, E. P., 1996, Dose-rate effect on radiation-induced DNA double-strand breaks in the human fibroblast HF19 cell line. International Journal of Radiation Biology, 69, 241-249.
7. Frankenberg-Schwager, M., Frankenberg, D. and Harbich, R., 1988, Exponential or shouldered survival curves result from repair of DNA double-strand breaks depending on post-irradiation conditions. Radiation Research, 114, 54-63.
8. Gumbrich, K., Virsik-Peuckert, R. P. and Harder, D., 1986, Temperature and the formation of radiation-induced chromosome aberrations. I. The effect of irradiation temperature. International Journal of Radiation Biology, 49, 665-672.
9. Lin, C. C., Draper, P. N. and Debraekeleer, M., 1985, High resolution chromosomal localization of the B gene of the human β-globin gene complex by in situ hybridization. Cytogenetics and Cell Genetics, 39, 269-274.
10. Lloyd, D. C., Purrott, R, J., Dolphin, G. W., Bolton, D. and Edwards, A. A., 1975, The relationship between chromosome aberrations and low LET radiation dose to human lymphocytes. International Journal of Radiation Biology, 28, 75-90.
11. Lucas, J. N., 1997, Dose reconstruction for individuals exposed to ionizing radiation using chromosome painting. Radiation Research, 148 (5 Suppl.), S33-S38.
12. Lucas, J. N., 1998, Cytogenetic signature for ionizing radiation. International Journal of Radiation Biology, 73, 15-20.
13. Lucas, J. N., Hill, F. S., Burk, C. E., Cox, A. B. and Straume, T., 1996, Stability of the translocation frequency following whole-body irradiation measured in rhesus monkeys. International Journal of Radiation Biology, 70, 309-318.
14. 60Co gamma rays. Health Physics, 68, 761-765.
15. 137Cs gamma rays. Radiation Protection Dosimetry, 71, 279-282.
16. Lucas, J. N. and Straume, T., 1996, Chromosome translocations measured by fluorescence in-situ hybridization: a promising biomarker. In American Society for Testing Materials (ASTM) - Fifth Symposium on Environmental Toxicology and Risk Assessment, Denver, CO, USA, edited by D. A. Bengston and D. S. Henshel (West Conshecken, PA: ASTM), pp. 109-116.
17. Prosser, J. S., Lloyd, D. C., Edwards, A. and Stather, J. W., 1983, The induction of chromosome aberrations in human lymphocytes by exposure to tritiated water in vitro. Radiation Protection Dosimetry, 4, 21-20.
18. Ramsey, M. J., Moore II, D. H., Briner, J. F., Lee, D. A., Olsen, L. A., Senft, J. R. and Tucker, J. D., 1994, The effects of age and lifestyle factors on the accumulation of cytogenetic damage as measured by chromosome painting. Mutation Research, 338, 95-106.
19. Resnick, M. A., 1976, The repair of double-strand breaks in DNA: a model involving recombination. Journal of Theoretical Biology, 59, 97-106.
20. Savage, J. R. K., 1975, Radiation-induced chromosomal aberrations in the plant Tradescantia: dose-response curves. Radiation Botany, 15, 87-140.
21. Straume, T. and Lucas, J. N., 1995, Validation studies for monitoring of workers using molecular cytogenetics. In Biomarkers in Occupational Health: Progress and Perspectives, edited by M. L. Mendelsohn, J. P. Peeters and M. J. Normandt (Washington, DC: Joseph Henry Press), pp. 174-193.
22. Straume, T., Lucas, J. N., Tucker, J. D., Bigbee, W. L. and Langlois, R. G., 1992, Biodosimetry for a radiation worker using multiple assays. Health Physics, 62, 122-130.
23. Virsik-Peuckert, R. P. and Harder, D., 1986, Temperature and the formation of radiation-induced chromosome aberrations. II. The temperature dependence of lesion repair and lesion interaction. International Journal of Radiation Biology, 49, 673-681.
24. Wei, Q., Mataoski, G. M., Farmer, E. R., Hedayati, M. A. and Grossman, L., 1993, DNA repair and aging in basal carcinoma: A molecular epidemiology study. Proceedings of National Academy of Science, 90, 1614-1618.