Dorsal column lesion prevents mechanical hyperalgesia and allodynia in osteotomy model

Pain

Volumn 82, Issue 1, 1999, Pages 73-80

  Houghton, Andrea K ^a   Hewitt, Elena ^b   Westlund, Karin N ^c  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b East South Temple Hospital   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Allodynia; Bone; Dorsal column pathway; Hyperalgesia; Pain; Spinal cord

Indexed keywords

ALLODYNIA; ANIMAL MODEL; ARTICLE; BONE INJURY; CONTROLLED STUDY; HYPERALGESIA; MALE; NONHUMAN; OSTEOTOMY; PRIORITY JOURNAL; RAT; SPINE INJURY;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; HYPERALGESIA; MALE; OSTEOTOMY; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; STRESS, MECHANICAL; TIBIA;

EID: 0033053540     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(99)00034-2     Document Type: Article

References (36)

1. Al-Chaer, E.D., Lawand, N.B., Westlund, K.N. and Willis, W.D., Visceral nociceptive input into the ventral posterolateral nucleus of the thalamus - a new function for the dorsal column pathway, J. Neurophysiol., 76 (1996a) 2661-2674.
2. Al-Chaer, E.D., Lawand, N.B., Westlund, K.N. and Willis, W.D., Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway, J. Neurophysiol., 76 (1996b) 2675-2690.
3. Al-Chaer, E.D., Westlund, K.N. and Willis, W.D., Potentiation of thalamic responses to colorectal distension by visceral inflammation, NeuroReport, 7 (1996c) 1635-1639.
4. Al-Chaer E.D., Feng Y., Willis W.D. Visceral pain: a disturbance in the sensorimotor continuum. Pain Forum. 7:1998;117-125.
5. Attal N., Jazat F., Kayser V., Guilbaud G. Further evidence for 'pain-related' behaviours in a model of unilateral peripheral mononeuropathy. Pain. 41:1990;235-251.
6. Brennan T.J., Vandermeulen E.P., Gebhart G.F. Characterization of a rat model of incisional pain. Pain. 64:1996;493-501.
7. Dobry P.J.K., Casey K.L. Roughness discrimination in cats with dorsal column lesions. Brain Res. 44:1972;385-397.
8. Dubner, R., Methods of assessing pain in animals. In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain, Vol. 3, Churchill Livingstone, New York, 1994, pp. 293-302.
9. Dubner R., Ruda M.A. Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurol. Sci. 15:1992;96-103.
10. Fernyhough J.C., Schimandle J.J., Weigel M.C., Edwards C.C., Levine A.M. Chronic donor site pain complicating bone graft harvesting from the posterior iliac crest for spinal fusion. Spine. 17:1992;1474-1480.
11. Glendinning D.S., Vierck C.J.J. Lack of a proprioceptive deficit after dorsal column lesions in monkeys. Neurology. 43:1993;363-366.
12. Gronblad M., Liesi P., Korkala O., Karahaiju E., Polak J. Innervation of human bone periosteum by peptidergic nerves. Anat. Rec. 209:1984;297-299.
13. Guilbaud G., Benoist J.M., Jazat F., Gautron M. Neuronal responsiveness in the ventrobasal thalamic complex of rats with an experimental peripheral mononeuropathy. J. Neurophysiol. 64:1990;1537-1554.
14. Haworth P.A., Roberts M.H.T. L-AP3 potently blocks the driving of cells in the gracile nucleus by dorsal column stimulation in the urethane-anaesthetized rat. J. Physiol. 476:1994;41P-42P.
15. Haworth, P.A. and Roberts, M.H.T., Activation of cutaneous receptive fields by a metobotropic glutamate receptor agonist in the gracile nucleus of the urethane-anaesthetized rat, J. Physiol., 483P (1995) 156P-157P.
16. Hirshberg R.M., Al-Chaer E.D., Lawand N.B., Westlund K.N., Willis W.D. Is there a pathway in the posterior funiculus that signals visceral pain? Pain. 67:1996;291-305.
17. Houghton, A.K., Hewitt, E. and Westlund, K.N., The effect of dorsal column lesions upon bone pain, Soc. Neurosci. Abstr., 22 (1996) 341.13.
18. Houghton A.K., Hewitt E., Westlund K.N. Enhanced withdrawal responses to mechanical and thermal stimuli after bone injury. Pain. 73:1997;325-337.
19. Houghton A.K., Valdez J.G., Westlund K.N. Peripheral morphine administration blocks the development of hyperalgesia and allodynia after bone damage in the rat. Anesthesiology. 898:1998;190-201.
20. Hurrell, D.J., The nerve supply of bone, J. Anat., 72 (1937) 54-61.
21. Hylden J.K.L., Nahin R.L., Traub R.J., Dubner R. Expansion of receptive fields of spinal lamina I projection neurons in rats with unilateral adjuvant-induced inflammation: the contribution of dorsal horn mechanisms. Pain. 37:1989;229-243.
22. Kolhekar R., Murphy S., Gebhart G.F. Thalamic NMDA receptors modulate inflammation-produced hyperalgesia in the rat. Pain. 71:1997;31-40.
23. Lewis, T., Pain, Macmillan, New York, 1942.
24. Merskey, H. and Bogduk, N., Classification of chronic pain: descriptions of chronic pain syndromes and definition of pain terms, IASP Press, Seattle, WA, 1994.
25. Mercadante S. Malignant bone pain: pathophysiology and treatment. Pain. 69:1997;1-18.
26. Milgram J.W., Robinson R.A. An electron microscopic demonstration of unmyelinated nerves in the Haversian canals of the adult dog. Bull. Johns Hopkins Hosp. 117:1965;163-173.
27. Miller M.R., Kasahara M. Observations on the innervation of human long bones. Anat. Rec. 145:1963;13-23.
28. Rees H., Roberts M.H.T. The anterior pretectal nucleus: a proposed role in sensory processing. Pain. 53:1993;121-135.
29. Schomburg E.D. Restrictions on the interpretation of spinal reflex modulation in pain and analgesia research. Pain Forum. 6:1997;101-109.
30. Schouenborg J., Holmberg H., Weng H.R. Functional organization of nociceptive withdrawal reflexes. 1. Activation of hindlimb muscles in the rat. Exp. Brain. Res. 83:1990;67-78.
31. Sherman M.S. The nerves of bone. J. Bone Joint Surg. Am. 45:1963;522-528.
32. Thurston T.J. Distribution of nerves in long bones as shown by silver impregnation. J. Anat. 134:1982;719-728.
33. Urban M.O., Jiang M.C., Gebhart G.F. Participation of central descending nociceptive facilitatory systems in secondary hyperalgesia produced by mustard oil. Brain Res. 737:1996;83-91.
34. Vierck, C.J.J. and Rand, R., Localization of touch on glaborous skin following dorsal column lesion in a primate, Soc. Neurosci. Abstr., 5 (1979) 715.
35. Wang, C.-C., Lu, Y., Winston, J., Pasricha, P.J. and Westlund, K.N., A new visceral pain pathway in the dorsal column: anatomical and functional studies of pancreatic pain including the effects of limited dorsal column lesions in rats, Gastroenterology, 114 (1998) A1188.
36. Willis, W.D. and Coggeshall, R.E., Sensory mechanisms of the spinal cord, Plenum Press, New York, 1991.