Leptin, but not a β3-adrenergic agonist, upregulates muscle uncoupling protein-3 messenger RNA expression: Short-term thermogenic interactions

Cellular and Molecular Life Sciences

Volumn 55, Issue 6-7, 1999, Pages 992-997

  Gomez Ambrosi J ^a   Fruhbeck G ^b   Martinez, J A ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

3 adrenergic agonist; Leptin; Rat; Uncoupling protein

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; LEPTIN; MESSENGER RNA; MUSCLE PROTEIN; UNCOUPLING PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; MALE; NONHUMAN; RAT; THERMOGENESIS;

ADIPOSE TISSUE, BROWN; ADRENERGIC BETA-AGONISTS; ANIMALS; BENZYL ALCOHOLS; BODY TEMPERATURE REGULATION; CARRIER PROTEINS; GENE EXPRESSION REGULATION; ION CHANNELS; LEPTIN; MALE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; OBESITY; ORGAN SPECIFICITY; PROTEIN BIOSYNTHESIS; PROTEINS; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0033050050     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00013203     Document Type: Article

References (41)

1. 1 Nicholls D. G. and Locke R. M. (1984) Thermogenic mechanisms in brown fat. Physiol. Rev. 64: 1-64
2. 2 Fleury C., Neverova M., Collins S., Raimbault S., Champigny O., Levi-Meyrueis C. et al. (1997) Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nature Genet. 15: 269-272
3. 3 Gimeno R. E., Dembski M., Weng X., Deng N., Shyjan A. W., Gimeno C. J. et al. (1997) Cloning and characterization of an uncoupling protein homolog. Diabetes 46: 900-906
4. 4 Boss O., Samec S., Paoloni-Giacobino A., Rossier C., Dulloo A., Seydoux J. et al. (1997) Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408: 39-42
5. 5 Vidal-Puig A., Solanes G., Grujic D., Flier J. S. and Lowell B. B. (1997) UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem. Biophys. Res. Commun. 235: 79-82
6. 6 Zhang Y., Proenca R., Maffei M., Barone M., Leopold L. and Friedman J. M. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432
7. 7 Wang J., Liu R., Hawkins M., Barzilai N. and Rossetti L. (1998) A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 393: 684-688
8. 8 Masuzaki H., Ogawa Y., Sagawa N., Hosoda K., Matsumoto T., Mise H. et al. (1997) Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nature Med. 3: 1029-1033
9. 9 Pelleymounter M. A., Cullen M. J., Baker M. B., Hecht R., Winters D., Boone T. et al. (1995) Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543
10. 10 Halaas J. L., Gajiwala K. S., Maffei M., Cohen S. L., Chait B. T., Rabinowitz D. et al. (1995) Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269: 543-546
11. 11 Campfield L. A., Smith F. J., Guisez Y., Devos R. and Burn P. (1995) Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549
12. 12 Collins S., Kuhn C. M., Petro A. E., Swick A. G., Chrunyk B. A. and Surwit R. S. (1996) Role of leptin in fat regulation. Nature 380: 677
13. 13 Martinez J. A. and Frühbeck G. (1996) Regulation of energy balance and adiposity: a model with new approaches. J. Physiol. Biochem. 52: 255-258
14. 14 Frühbeck G., Aguado M. and Martinez J. A. (1997) In vitro lipolytic effect of leptin on mouse adipocytes: evidence for a possible autocrine paracrine role of leptin. Biochem. Biophys. Res. Commun. 240: 590-594
15. 15 Siegrist-Kaiser C. A., Pauli V., Juge-Aubry C. E., Boss O., Pernin A., Chin W. W. et al. (1997) Direct effects of leptin on brown and white adipose tissue. J. Clin. Invest. 100: 2858-2864
16. 16 Liu Y.-L., Emilsson V. and Cawthorne M. A. (1997) Leptin inhibits glycogen synthesis in the isolated soleus muscle of obese (ob/ob) mice. FEBS Lett. 411: 351-355
17. 17 Muoio D. M., Dohn G. L., Fiedorek F. T. Jr., Tapscott E. B. and Coleman R. A. (1997) Leptin directly alters lipid partitioning in skeletal muscle. Diabetes 46: 1360-1363
18. 3-Adrenergic agonists. Drugs Fut. 18: 529-549
19. 3-adrenoceptor in the regulation of body composition. J. Clin. Invest. 100: 1098-1106
20. 3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes. Endocrinology 137: 4054-4057
21. 21 Collins S. and Surwit R. S. (1996) Pharmacologie manipulation of ob expression in a dietary model of obesity. J. Biol. Chem. 271: 9437-9440
22. 3 adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice. Diabetes 45: 909-914
23. 3-adrenoceptor agonists BRL 35135A and ZD2079. Biochem. Biophys. Res. Commun. 228: 605-610
24. 3-Adrenergic-mediated suppression of leptin gene expression in rats. Am. J. Physiol. 272: E1031-E1036
25. 3-adrenoceptors. Life Sci. 59: 141-146
26. 3-adrenergic receptors. FASEB J. 10: A504
27. 27 Spence C. A. and Hansen-Smith F. M. (1978) Comparison of the chemical and biochemical composition of thirteen muscles of the rat alter dietary protein restriction. Br. J. Nutr. 39: 647-658
28. 3-adrenergic agonist in rats fed on a cafeteria diet. Eating Weight Disord. 2: 130-137
29. 29 Norusis M. J. (1994) SPSS Advanced Statistics 6.1.3, SPSS Inc., Chicago
30. 30 Sennitt M. V., Arch J. R. S., Levy A. L., Simson D. L., Smith S. A. and Cawthorne M. A. (1985) Anti-hyperglycaemic action of BRL 26830, a novel β-adrenoceptor agonist, in mice and rats. Biochem. Pharmacol. 34: 1279-1285
31. 31 Hers H. G. and Hue L. (1983) Gluconeogenesis and related aspects of glycolysis. Ann. Rev. Biochem. 52: 617-653
32. 3-adrenergic agonist CGP-12177. Cell. Mol. Life Sci. 54: 191-195
33. 33 Frühbeck G., Garcia-Granero M. and Martinez J. A. (1998) Role of fragment peptides from ob protein on body weight and thermogenesis control: a screening. Regul. Pept. 73: 83-87
34. 3-adrenoceptors compared in brown adipose tissue and in skeletal muscle membranes. Br. J. Pharmacol. 109: 1157-1163
35. 3-adrenergic agonists, and leptin. J. Biol. Chem. 272: 24129-24132
36. 3-adrenergic agonist BRL 35135 and metformin in obese fa/fa Zucker rats. Biochem. Biophys. Res. Commun. 246: 899-904
37. 37 Frühbeck G., Gómez-Ambrosi J. and Martinez J. A. (1998) Relationship between pre-and postprandial expression of the leptin receptor splice variants OB-Ra and OB-Rb in murine peripheral tissues. Eur. J. Clin. Invest. 28: A31
38. 38 Liu Q., Bai C., Chen F., Wang R., MacDonald T., Gu M. et al. (1998) Uncoupling protein-3: a muscle-specific gene upregulated by leptin in ob/ob mice. Gene 207: 1-7
39. 39 Scarpace P. J., Matheny M., Pollock B. H. and Tümer N. (1997) Leptin increases uncoupling protein expression and energy expenditure., Am. J. Physiol. 273: E226-E230
40. 40 Sarmiento U., Benson B., Kaufman S., Ross L., Qi M., Scully S. et al. (1997) Morphologie and molecular changes induced by recombinant human leptin in the white and brown adipose tissues of C57BL/6 mice. Lab. Invest. 77: 243-256
41. 41 Harris R. B. S., Zhou J., Redmann S. M. Jr., Smagin G. N., Smith S. R., Rodgers E. et al. (1998) A leptin dose-response study in obese (ob/ob) and lean (+ ?) mice. Endocrinology 139: 8-19