Telomerase activity in malignant ovarian tumors with deregulation of cell cycle regulatory proteins

Cancer Letters

Volumn 142, Issue 2, 1999, Pages 207-217

  Terasawa, Katsuhiko ^a   Sagae, Satoru ^a   Takeda, Tomoyuki ^a   Ishioka, Shinichi ^a   Kobayashi, Kanji ^a   Kudo, Ryuichi ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cyclin D1; Cyclin E; p16; p53; Retinoblastoma protein; Telomerase; TRAP assay

Indexed keywords

CYCLIN E; CYCLINE; TELOMERASE;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; DEREGULATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OVARY TUMOR; PRIORITY JOURNAL; STAINING;

ADULT; AGED; AGED, 80 AND OVER; CELL CYCLE PROTEINS; CYCLIN D1; CYCLIN E; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; G1 PHASE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; NEOPLASM STAGING; OVARIAN NEOPLASMS; POLYMERASE CHAIN REACTION; TELOMERASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0033049207     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00170-6     Document Type: Article

References (30)

1. Kim N.W., Piatyszek M.A., Prowse K.R., et al. Specific association of human telomerase activity with immortal cells and cancer. Science. 266:1994;2011-2015.
2. Shay J.W., Bacchetti S. survey of telomerase activity in human cancer. Eur. J. Cancer. 33:1997;787-791.
3. Kyo S., Inoue M., Kohama T., Takakura M. Telomerase activity in human endometrium. Cancer Res. 57:1997;610-614.
4. Counter C.M., Bacchetti S., Leber B., Harley C.B., Gupta J. Telomerase activity in normal leukocytes and in hematological malignancies. Blood. 85:1995;2315-2320.
5. Wan M., Dubeau L., Zhao Y., Felix J.C., Duggan B.D., Li W.Z. Telomerase activity in benign and malignant epithelial ovarian tumors. J. Natl. Cancer Inst. 89:1997;437-441.
6. Kyo S., Kanaya T., Ishikawa H., Ueno H., Inoue M. Telomerase activity in gynecological tumors. Clin. Cancer Res. 2:1996;2023-2028.
7. Zheng P.S., Sugimori H., Matsuyama T., Fukuda K., Nakao Y., Yokoyama M., Ochida M., Yamasaki F., Iwasaka T. Telomerase activity in gynecologic tumors. Gynecol. Oncol. 64:1997;171-175.
8. Gorham H., Goodison S., Tarin D., Charnock M., Manek S., Marsh G., Sugino T., Yoshida K. Telomerase activity in human gynecological malignancies. J. Clin. Pathol. 50:1997;501-504.
9. Murakami J., Ide T., Tahara H., Ohama K., Nagai N. Telomerase activity in ovarian tumors. Cancer. 80:1997;1085-1092.
10. Chadeneau C., Bacchetti S., Gallinger S., Hirte H.W., Hay K. Telomerase activity associated with acquisition of malignancy in human colorectal cancer. Cancer Res. 55:1995;2533-2536.
11. Lin Y., Mayamoto H., Fujinami K., Uemura H., Hosaka M., Iwasaki Y., Kubota Y. Telomerase activity in human bladder cancer. Cancer Res. 2:1996;929-932.
12. Hiyama E., Shay J.W., Piatyszek M.A., Hiyama K., Gazdar A.F., Yokoyama T., Kuroi K., Kataoka T., Gollahon L. Telomerase activity in human breast tumors. J. Natl. Cancer Inst. 88:1996;116-122.
13. Scully R.E. Ovarian tumor, A review. Am. J. Pathol. 87:1977;686-720.
14. Holt S.E., Shay J.W., Wright W.E. Multiple pathways for the regulation of telomerase activity. Eur. J. Cancer. 33:1997;761-766.
15. Holt S.E., Aisner D.L., Shay J.W., Wright W.E. Lack of cell cycle regulation of telomerase activity. Proc. Natl. Acad. Sci. USA. 94:1997;10687-10692.
16. Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell. 81:1995;323-330.
17. Landberg G., Roos G., Cajander J., Emdin S.O., Nilsson P., Nielsen N.H. Telomerase activity is associated with cell cycle deregulation in human breast cancer. Cancer Res. 57:1997;549-554.
18. Xu H.J., Hu S.X., Li J., Mills G.B., Bast R.C., Kong C.T., Kruzelock R., Perng G.S., Ji W., Zhou Y. Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition. Oncogene. 15:1997;2589-2596.
19. Holt S.E., Norton J.C., Wright W.E., Shay J.W. Comparison of the telomeric repeat amplification protocol (TRAP) to new TRAP-eze telomerase detection kit. Methods Cell Sci. 18:1996;237-248.
20. Hiyama E., Hiyama K., Tatsumoto N., Shay J.W., Yokoyama T. Telomerase activity in human intestine. Int. J. Oncol. 9:1996;453-458.
21. Taylor R.S., Ramirez R.D., Ogoshi M., Chaffins M., Piatyszek M.A., Shay J.W. Detection of telomerase activity in malignant and non-malignant skin conditions. J. Invest Dermatol. 106:1996;759-765.
22. Geradts J., Kratzke R.A., Niehans G.A., Lincoln C.E. Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors: correlation with retinoblastoma protein expression. Cancer Res. 55:1995;6006-6011.
23. Worsley S.D., Ponder B.A.J., Davies B.R. Over-expression of cyclin D1 in epithelial ovarian cancer. Gynecol. Oncol. 64:1997;189-195.
24. Hiyama E., Shay J.W., Piatyszek M.A., Matsuura Y., Yokoyama T., Hiyama K. Correlating telomerase activity levels with human neuroblastoma outcomes. Nat. Med. 1:1995;249-255.
25. Langford L.A., Piatyszek M.A., Xu R., Schold S.C., Wright W.E., Shay J.W. Telomerase activity in ordinary meningiomas predicts poor outcome. Hum. Pathol. 28:1997;416-420.
26. Hirose M., Abe-Hashimoto J., Ogura K., Tahara H., Ide T., Yoshimura T. rapid, useful and quantitative method to measure telomerase activity by hybridization protection assay connected with a telomeric repeat amplification protocol. J. Cancer Res. Clin. Oncol. 123:1997;337-344.
27. Tatematsu K., Ishikawa F., Omine M., Sato H., Shionoya S., Danbara M., Nakayama J. A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemia. Oncogene. 13:1996;2265-2274.
28. Ohyashiki K., Ohyashiki J.H., Nishimaki J., Toyama K., Ebihara Y., Kato H., Wright W.E., Shay J.W. Cytological detection of telomerase activity using an in situ telomeric repeat amplification protocol assay. Cancer Res. 57:1997;2100-2103.
29. Nakayama J., Tahara H., Saito M., Ito K., Nakamura H., Nakanishi T., Tahara E., Ide T., Ishikawa F. Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas. Nat. Genet. 18:1998;65-68.
30. Mandel M., Kumar R. Bcl-2 modulates telomerase activity. J. Biol. Chem. 272:1997;14183-14187.