Helicobacter pylori non-cytotoxic genotype enhances mucosal gastrin and mast cell tryptase

Journal of Clinical Pathology

Volumn 52, Issue 3, 1999, Pages 210-214

  Basso, D ^a   Navaglia, F ^a   Brigato, L ^a   Di Mario, F ^b   Rugge, M ^b   Plebani, M ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b NONE

Author keywords

Gastrin; Helicobacter pylori; Mast cells; Tryptase

Indexed keywords

TRYPTASE;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; BACTERIAL INFECTION; CYTOTOXICITY; FEMALE; GASTRIN RELEASE; GENOTYPE; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; MAST CELL; PATHOGENICITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH MUCOSA;

EID: 0033046969     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.52.3.210     Document Type: Article

References (38)

1. 1 Bayerdorffer E, Neubauer A, Rudolph B, et al. Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet 1995;345:1591-4.
2. 2 Calvert R, Randerson J, Evans P, et al. Genetic abnormalities during transition from Helicobacter-pylori-associated gastritis to low-grade MALToma. Lancet 1995;345:26-7.
3. 3 McFarlane GA, Munro A. Helicobacter pylori and gastric cancer. Br J Surg 1997; 84:1190-9.
4. 4 Peek RM, Blaser MJ. Pathophysiology of Helicobacter pylori-induced gastritis and peptic ulcer disease. Am J Med 1997;102:200-7.
5. 5 Blaser MJ. Helicobacter pylori phenotypes associated with peptic ulceration. Scand J Gastroenterol 1994;29(suppl 205):1-5.
6. 6 Atherton JC, Cao P, Peek RM, et al. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 1995;270:17771-7.
7. 7 Cover TL. The vacuolating cytotoxin of Helicobacter pylori. Mol Microbiol 1996;20:241-6.
8. 8 Atherton JC, Peek RM, Tham KT, et al. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology 1997;112:92-9.
9. 9 Atherton JC. The clinical relevance of strain types of Helicobacter pylori. Gut 1997;40:701-3.
10. 10 Phadnis SH, Ilver D, Janzon L, et al. Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori. Infect Immun 1994;62:1157-65.
11. 11 Xiang Z, Censini S, Bayeli PF, et al. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin. Infect Immun 1995;63:94-8.
12. 12 Covacci A, Censini S, Bugnoli M, et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 1993;90:5791-5.
13. 13 Censini S, Lange C, Xiang Z, et al. cag, A pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci USA 1996; 93:14648-53.
14. 14 Graham DY, Opekun A, Lew GM, et al. Helicobacter pylori-associated exaggerated gastrin release in duodenal ulcer patients. Gastroenterology 1991;100:1571-5.
15. 15 Moss SF, Legon S, Bishop AE, et al. Effect of Helicobacter pylori on gastric on gastrin somatostatin in duodenal ulcer disease. Lancet 1992;340:930-2.
16. 16 Graham DY, Lew GM, Lechago J. Antral G-cell and D-cell numbers in Helicobacter pylori infection: effect of H. pylori eradication. Gastroenterology 1993;104:1655-60.
17. 17 Haruma K, Sumii K, Okamoto S, et al. Helicobacter pylori infection is associated with low antral somatostatin content in young adults. Scand J Gastroenterol 1995;30:550-3.
18. 18 Plebani M, Basso D, Cassaro M, et al. Helicobacter pylori serology in patients with chronic gastritis. Am J Gastroenterol 1996;91:954-8.
19. 19 Warburton VJ, Everett S, Mapstone NP, et al. Clinical and histological associations of cagA and vacA genotypes in Helicobacter pylori gastritis. J Clin Pathol 1998;51:55-61.
20. 20 Crabtree JE, Farmery SM, Lindley IJD, et al. CagA/ cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J Clin Pathol 1994;47:945-50.
21. 21 Gionchetti P, Vaira D, Campieri M, et al. Enhanced mucosal interleukin-6 and -8 in Helicobacter pylori-positive dyspeptic patients. Am J Gastroenterol 1994;89:883-7.
22. 22 Moss SF, Legon S, Davies J, et al. Cytokine gene expression in Helicobacter pylori associated antral gastritis. Gut 1994; 35:1567-70.
23. 23 Crowe SE, Alvarez L, Dytoc M, et al. Expression of interleukin 8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro. Gastroenterology 1995;108:65-74.
24. 24 Basso D, Scrigner M, Toma A, et al. Helicobacter pylori infection enhances mucosal interleukin-1 beta, interleukin-6, and the soluble receptor of interleukin-2. Int J Clin Lab Res 1996;26:207-10.
25. 25 Abraham SN, Malaviya R. Mast cells in infection and immunity. Infect Immun 1997;65:3501-8.
26. 26 Bechi P, Dei R, Di Bello MG, et al. Helicobacter pylori potentiates histamine release from serosal rat mast cells in vitro. Dig Dis Sci 1993;38:944-9.
27. 27 Kurose I, Granger DN, Evans DJ, et al. Helicobacter pylori-induced microvascular protein leakage in rats: role of neutrophils, mast cells, and platelets. Gastroenterology 1994; 107:70-9.
28. 28 Nakajima S, Krishnan B, Ota H, et al. Mast cell involvement in gastritis with or without Helicobacter pylori infection. Gastroenterology 1997;113:746-54.
29. 29 Plebani M, Di Mario F, Dal Santo PG, et al. Measurement of pepsinogen group I in endoscopic gastroduodenal biopsies. Clin Chem 1990;36:682-4.
30. 30 Dixon MF, Genta RM, Yardley JH, et al. Classification and grading of gastritis. The updated Sydney system. Am J Surg Pathol 1996;20:1161-81.
31. 31 Basso D, Navaglia F, Cassaro M, et al. Gastric juice polymerase chain reaction: an alternative to histology in the diagnosis of Helicobacter pylori infection. Helicobacter 1996;1:159-64.
32. 32 Navaglia F, Basso D, Piva MG, et al. Helicobacter pylori cytotoxic genotype is associated with peptic ulcer and influences serology. Am J Gastroenterol 1198;93:227-30.
33. 33 Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72: 248-54.
34. 34 Plebani M, Basso D, Busatto G, et al. Are tryptase and cathepsin D related to Helicobacter pylori infection and mucosal gastrin in peptic ulcer? Res Exp Med 1994;194:1-8.
35. 35 Bechi P, Romagnoli P, Panula P, et al. Gastric mucosal histamine storing cells. Evidence for different roles of mast cells and enterochromaffin-like cells in humans. Dig Dis Sci 1995;40:2207-13.
36. 36 Plebani M, Basso D, Busatto G, et al. Gastrin stimulates gastric mast cells in rabbits. Res Exp Med 1995;195:365-71.
37. 37 Gillen D, El-Omar EM, Wirz AA, et al. The acid response to gastrin distinguishes duodenal ulcer patients from Helicobacter pylori-infected healthy subjects. Gastroenterology 1998;114:50-7.
38. 38 Cairns JA, Walls AF. Mast cell tryptase is a mitogen for epithelial cells. Stimulation of IL-8 production and intercellular adhesion molecule-1 expression. J Immunol 1996;156: 275-83.