메뉴 건너뛰기




Volumn 27, Issue 1, 1999, Pages 86-91

In vitro metabolism of the HIV-1 protease inhibitor ABT-378: Species comparison and metabolite identification

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; HUMAN DEFICIENCY VIRUS 1 PROTEINASE INHIBITOR; LOPINAVIR; PROTEIN; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; UREA;

EID: 0033043367     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (70)

References (17)
  • 5
    • 0345179369 scopus 로고    scopus 로고
    • Potent inhibition of the in vitro human liver microsomal metabolism of the HIV-1 protease inhibitor ABT-378 by ritonavir: Potential for a positive drug interaction
    • January 1997, Abstract 211
    • Kumar GN, Dykstra J, Jayanti V and Denissen JF (1997) Potent inhibition of the in vitro human liver microsomal metabolism of the HIV-1 protease inhibitor ABT-378 by ritonavir: Potential for a positive drug interaction. Proceedings of 4th Conference on Retroviruses and Opportunistic Infections, January 1997, Abstract 211.
    • (1997) Proceedings of 4th Conference on Retroviruses and Opportunistic Infections
    • Kumar, G.N.1    Dykstra, J.2    Jayanti, V.3    Denissen, J.F.4
  • 6
    • 0030430035 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
    • Kumar GN, Rodrigues AD, Buko AM and Denissen JF (1996) Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther 277;423-431.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 423-431
    • Kumar, G.N.1    Rodrigues, A.D.2    Buko, A.M.3    Denissen, J.F.4
  • 14
    • 0028838715 scopus 로고
    • Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey and cynomolgus monkey
    • Sharer JE, Shipley LA, VandenBranden MR. Binkley SA and Wrighton SA 11995) Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey and cynomolgus monkey. Drug Metab Dispos 23:1231-1241.
    • (1995) Drug Metab Dispos , vol.23 , pp. 1231-1241
    • Sharer, J.E.1    Shipley, L.A.2    VandenBranden, M.R.3    Binkley, S.A.4    Wrighton, S.A.5
  • 15
    • 0030959377 scopus 로고    scopus 로고
    • Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys and humans
    • Shimada T, Mimura M, Inoue K, Nakamura S, Oda H, Ohmori S and Yamazaki H (1997) Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys and humans. Arch Toxicol 71:401-408.
    • (1997) Arch Toxicol , vol.71 , pp. 401-408
    • Shimada, T.1    Mimura, M.2    Inoue, K.3    Nakamura, S.4    Oda, H.5    Ohmori, S.6    Yamazaki, H.7
  • 16
    • 0030849517 scopus 로고    scopus 로고
    • Clinically effective HIV-1 protease inhibitors
    • Vacca JP and Condra JH (1997) Clinically effective HIV-1 protease inhibitors. Drug Discov Today 2:261-272.
    • (1997) Drug Discov Today , vol.2 , pp. 261-272
    • Vacca, J.P.1    Condra, J.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.