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Tomato Prf is a member of the leucine-rich repeat class of plant disease resistance genes and lies embedded within the Pto kinase gene cluster
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Salmeron JM, Oldroyd GED, Rommens CMT, Scofield S, Kim HS, Lavelle DT, Dahlbeck D, Staskawicz BJ Tomato Prf is a member of the leucine-rich repeat class of plant disease resistance genes and lies embedded within the Pto kinase gene cluster. Cell. 86:1996;123-133.
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Salmeron, J.M.1
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Kim, H.S.5
Lavelle, D.T.6
Dahlbeck, D.7
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44
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0032544048
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Genetically engineered broad- spectrum disease resistance in tomato
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This report provides evidence that broad spectrum disease resistance can be achieved by manipulating expression of signal transduction components. Overexpression of Prf, a tomato gene required for Pto-mediated resistance, leads to resistance of the plant to normally virulent pathogens. The authors show that this resistance involves salicylic acid
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Oldroyd GED, Staskawicz BJ Genetically engineered broad- spectrum disease resistance in tomato. Proc Natl Acad Sci USA. 95:1998;10300-10305. This report provides evidence that broad spectrum disease resistance can be achieved by manipulating expression of signal transduction components. Overexpression of Prf, a tomato gene required for Pto-mediated resistance, leads to resistance of the plant to normally virulent pathogens. The authors show that this resistance involves salicylic acid.
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Proc Natl Acad Sci USA
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Oldroyd, G.E.D.1
Staskawicz, B.J.2
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45
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0029560869
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The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response
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Zhou J, Loh YT, Bressan RA, Martin GB The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response. Cell. 83:1995;925-935.
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Zhou, J.1
Loh, Y.T.2
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Martin, G.B.4
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46
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0030973457
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The Pto kinase conferring resistance to tomato bacterial speck disease interacts with proteins that bind a cis-element of pathogenesis-related genes
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This elegant study shows that signal transduction from the R gene product (in the cytoplasm) to gene induction (in the nucleus) can be quite short
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Zhou J, Tang X, Martin GB The Pto kinase conferring resistance to tomato bacterial speck disease interacts with proteins that bind a cis-element of pathogenesis-related genes. EMBO J. 16:1997;3207-3218. This elegant study shows that signal transduction from the R gene product (in the cytoplasm) to gene induction (in the nucleus) can be quite short.
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Zhou, J.1
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Martin, G.B.3
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47
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0029743977
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Spontaneous and induced mutations in a single open reading frame alter both virulence and avirulence in Xanthomonas campestris pv. vesicatoria avrBs2
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Swords KMM, Dahlbeck D, Kearney B, Roy M, Staskawicz BJ Spontaneous and induced mutations in a single open reading frame alter both virulence and avirulence in Xanthomonas campestris pv. vesicatoria avrBs2. J Bacteriol. 178:1996;4661-4669.
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Swords, K.M.M.1
Dahlbeck, D.2
Kearney, B.3
Roy, M.4
Staskawicz, B.J.5
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48
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0029294122
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The avrRpm1 gene of Pseudomonas syringae pv. maculicola is required for virulence on Arabidopsis
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Ritter C, Dangl JL The avrRpm1 gene of Pseudomonas syringae pv. maculicola is required for virulence on Arabidopsis. Mol Plant-Microbe Interact. 8:1995;444-453.
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0032477884
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Homology and functional similarity of an hrp-linked pathogenicity locus, dspEF, of Erwinia amylovora and the avirulence locus avrE of Pseudomonas syringae pathovar tomato
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This is one of the most important recent papers in this field. The authors demonstrate functional homology between two genes from different bacterial genera, dspE and avrE, that were previously described to be involved in pathogenicity and avirulence, respectively. This finding supports the idea that avirulence genes have a function in pathogenicity and that the outcome of the interaction depends on the genotype of the host
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Bogdanove AJ, Kim JF, Wei Z, Kolchinsky P, Charkowski AO, Conlin AK, Collmer A, Beer SV Homology and functional similarity of an hrp-linked pathogenicity locus, dspEF, of Erwinia amylovora and the avirulence locus avrE of Pseudomonas syringae pathovar tomato. Proc Natl Acad Sci USA. 95:1998;1325-1330. This is one of the most important recent papers in this field. The authors demonstrate functional homology between two genes from different bacterial genera, dspE and avrE, that were previously described to be involved in pathogenicity and avirulence, respectively. This finding supports the idea that avirulence genes have a function in pathogenicity and that the outcome of the interaction depends on the genotype of the host.
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Proc Natl Acad Sci USA
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Bogdanove, A.J.1
Kim, J.F.2
Wei, Z.3
Kolchinsky, P.4
Charkowski, A.O.5
Conlin, A.K.6
Collmer, A.7
Beer, S.V.8
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50
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0029328323
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Xanthomonas avirulence/pathogenicity gene family encodes functional plant nuclear targeting signals
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Yang Y, Gabriel DW Xanthomonas avirulence/pathogenicity gene family encodes functional plant nuclear targeting signals. Mol Plant-Microbe Interact. 8:1995;627-631.
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51
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0032145159
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AvrXa10 contains an acidic transcriptional activation domain in the functionally conserved C terminus
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This paper draws attention to a very interesting structural feature of a bacterial avirulence protein of the AvrBs3 family. It is intriguing that bacterial proteins may act on eukaryotic transcription via an acidic activation domain
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Zhu W, Yang B, Chittoor JM, Johnson LB, White FF AvrXa10 contains an acidic transcriptional activation domain in the functionally conserved C terminus. Mol Plant-Microbe Interact. 11:1998;824-832. This paper draws attention to a very interesting structural feature of a bacterial avirulence protein of the AvrBs3 family. It is intriguing that bacterial proteins may act on eukaryotic transcription via an acidic activation domain.
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Mol Plant-Microbe Interact
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Zhu, W.1
Yang, B.2
Chittoor, J.M.3
Johnson, L.B.4
White, F.F.5
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52
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0032959253
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Regulation of expression of avirulence gene avrRxv and identification of a family of host interaction factors by sequence analysis of avrBsT
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in press
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Ciesiolka LD, Hwin T, Gearlds JD, Minsavage GV, Saenz R, Bravo M, Handley V, Conover SM, Zheng H, Caporgno J et al.: Regulation of expression of avirulence gene avrRxv and identification of a family of host interaction factors by sequence analysis of avrBsT. Mol Plant-Microbe Interact 1999, 12:in press.
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Mol Plant-Microbe Interact
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Ciesiolka, L.D.1
Hwin, T.2
Gearlds, J.D.3
Minsavage, G.V.4
Saenz, R.5
Bravo, M.6
Handley, V.7
Conover, S.M.8
Zheng, H.9
Caporgno, J.10
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53
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0030985415
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Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death
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Monack DM, Mecsas J, Ghori N, Falkow S Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death. Proc Natl Acad Sci USA. 94:1997;10385-10390.
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Monack, D.M.1
Mecsas, J.2
Ghori, N.3
Falkow, S.4
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54
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0031780201
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YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK
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Palmer LE, Hobbie S, Galan JE, Bliska JB YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol Microbiol. 27:1998;953-965.
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Palmer, L.E.1
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Galan, J.E.3
Bliska, J.B.4
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55
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0028982926
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Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance
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Grant MR, Godiard L, Straube E, Ashfield T, Lewald J, Sattler A, Innes RW, Dangl JL Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance. Science. 269:1995;843-846.
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Grant, M.R.1
Godiard, L.2
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Ashfield, T.4
Lewald, J.5
Sattler, A.6
Innes, R.W.7
Dangl, J.L.8
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56
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0028113076
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RPS2 of Arabidopsis thaliana: A leucine-rich repeat class of plant disease resistance genes
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Bent AF, Kunkel BN, Dahlbeck D, Brown KL, Schmidt R, Giraudat J, Leung J, Staskawicz BJ RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes. Science. 265:1994;1856-1860.
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Science
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Bent, A.F.1
Kunkel, B.N.2
Dahlbeck, D.3
Brown, K.L.4
Schmidt, R.5
Giraudat, J.6
Leung, J.7
Staskawicz, B.J.8
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57
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0027989564
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The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats
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Mindrinos M, Katagiri F, Yu GL, Ausubel FM The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell. 78:1994;1089-1099.
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Cell
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Mindrinos, M.1
Katagiri, F.2
Yu, G.L.3
Ausubel, F.M.4
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58
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0032170811
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A mutation within the leucine-rich repeat domain of the Arabidopsis disease resistance gene RPS5 partially suppresses multiple bacterial and downy mildew resistance genes
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Warren RF, Henk A, Mowery P, Holub E, Innes RW A mutation within the leucine-rich repeat domain of the Arabidopsis disease resistance gene RPS5 partially suppresses multiple bacterial and downy mildew resistance genes. Plant Cell. 10:1998;1439-1452.
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Plant Cell
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Warren, R.F.1
Henk, A.2
Mowery, P.3
Holub, E.4
Innes, R.W.5
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59
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0032130147
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Structure and function of proteins controlling strain-specific pathogen resistance in plants
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An up to date overview of the features of plant disease resistance genes isolated so far
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Ellis J, Jones D Structure and function of proteins controlling strain-specific pathogen resistance in plants. Curr Opin Plant Biol. 1:1998;288-293. An up to date overview of the features of plant disease resistance genes isolated so far.
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Curr Opin Plant Biol
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Ellis, J.1
Jones, D.2
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