Recognition specificity for the bacterial avirulence protein AvrPto is determined by Thr-204 in the activation loop of the tomato Pto Kinase

Molecular Cell

Volumn 2, Issue 2, 1998, Pages 241-245

  Frederick, Reid D ^a,b   Thilmony, Roger L ^a   Sessa, Guido ^a   Martin, Gregory B ^a,c  

^a PURDUE UNIVERSITY   (United States)

^b USDA ARS Foreign Disease Weed Science Research Unit   (United States)

^c United States Department of Agriculture Agricultural Research Service and Boyce Thompson Institute for Plant Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AVRPTO PROTEIN, PSEUDOMONAS SYRINGAE; BACTERIAL PROTEIN; HYBRID PROTEIN; PROTEIN SERINE THREONINE KINASE; PTO PROTEIN, LYCOPERSICON; VEGETABLE PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; PATHOGENICITY; PLANT; PSEUDOMONAS; RHIZOBIUM; SITE DIRECTED MUTAGENESIS; TOBACCO; TOMATO; TRANSGENIC PLANT; VIRULENCE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BINDING SITES; LYCOPERSICON ESCULENTUM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PLANT PROTEINS; PLANTS, GENETICALLY MODIFIED; PLANTS, TOXIC; PROTEIN-SERINE-THREONINE KINASES; PSEUDOMONAS; RECOMBINANT FUSION PROTEINS; RHIZOBIUM; TOBACCO; VIRULENCE;

EID: 0032135461     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80134-3     Document Type: Article

References (25)

1. Alfano, J.R., and Collmer, A. (1996). Bacterial pathogens in plants: life up against the wall. Plant Cell 8, 1683-1698.
2. Ausubel, P.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., and Struhl, K. (1996). Analysis of protein interactions. In Current Protocols in Molecular Biology (Suppl.) (New York: John Wiley and Sons), pp. 20.1.22-20.1.23.
3. Bent, A.F. (1996). Plant disease resistance genes: function meets structure. Plant Cell 8, 1757-1771.
4. Dangl, J.L. (1994). The enigmatic avirulence genes of phytopathogenic bacteria. In Current Topics in Microbiology and Immunology, Vol. 192., J. L. Dangl, ed. (Berlin: Springer-Verlag), pp. 99-118.
5. De Bondt, H.L., Rosenblatt, R., Jancarik, J., Jones, H.D., Morgan, D.O., and Kim, S.-H. (1993). Crystal structure of cyclin-dependent kinase 2. Nature 363, 595-602.
6. Goodman, R.N., and Novacky, A.J. (1994). The bacteria-induced hypersensitive reaction. In The Hypersensitive Reaction in Plants to Pathogens (St. Paul, MN: American Phytopathol. Soc.), pp. 117-173.
7. Gopalan, S., Bauer, D.W., Alfano, J.R., Loniello, A.O., He, S.Y., and Collmer, A. (1996). Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence in the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death. Plant Cell 8, 1095-1105.
8. Hammond-Kosack, K.E., and Jones, J.D.G. (1997). Plant disease resistance genes. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48, 575-607.
9. Jia, Y., Loh, Y.-T., Zhou, J., and Martin, G.B. (1997). Alleles of Pfo and Fen occur in bacterial speck-susceptible and fenthion-insensitive tomato lines and encode functional protein kinases. Plant Cell 9, 61-73.
10. Johnson, L.N., Noble, M.E.M., and Owen, D.J. (1996). Active and inactive protein kinases: structural basis for regulation. Cell 85, 149-158.
11. Keen, N.T. (1990). Gene-for-gene complementarity in plant-pathogen interactions. Annu. Rev. Genet. 24, 447-463.
12. Lee, C.A. (1997). Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells? Trends Microbiol. 5, 148-156.
13. Leister, R.T., Ausubel, F.M., and Katagiri, F. (1996). Molecular recognition of pathogen attack occurs inside of plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1. Proc. Natl. Acad. Sci. USA 93, 15497-15502.
14. Martin, G.B., Brommonschenkel, S.H., Chunwongse, J., Frary, A., Ganal, M.W., Spivey, R., Wu, T., Earle, E.D., and Tanksley, S.D. (1993). Map-based cloning of a protein kinase gene conferring disease resistance in tomato. Science 262, 1432-1436.
15. Martin, G.B., Frary, A., Wu, T., Brommonschenkel, S., Chunwongse, J., Earle, E.D., and Tanksley, S.D. (1994). A member of the Pto gene family confers sensitivity to fenthion resulting in rapid cell death. Plant Cell 6, 1543-1552.
16. Mudgett, M.B., and Staskawicz, B.J. (1998). Protein signaling via type III secretion pathways in phytopathogenic bacteria. Curr. Opin. Microbiol. 1, 109-114.
17. Roine, E., Wei, W., Yuan, J., Nurmiaho-Lassila, E.-L., Kalkkinen, N., Romantschuk, M., and He, S.Y. (1997). Hrp pilus: an hrp-dependent bacterial surface appendage produced by Pseudomonas syringae pv. tomato DC3000. Proc. Natl. Acad. Sci. USA 94, 3459-3464.
18. Ronald, P.C., Salmeron, J.M., Garland, F.M., and Staskawicz, B.J. (1992). The cloned avirulence gene avrPto induces disease resistance in tomato cultivars containing the Pto resistance gene. J. Bacteriol. 174, 1604-1611.
19. Salmeron, J.M., and Staskawicz, B.J. (1993). Molecular characterization and hrp dependence of the avirulence gene avrPto from Pseudomonas syringae pv. tomato. Mol. Gen. Genet. 239, 6-16.
20. Salmeron, J.M., Oldroyd, G.E.D., Rommens, G.M.T., Scofield, S.R., Kim, H.-S., Lavelle, D.T., Dahlbeck, D., and Staskawicz, B.J. (1996). Tomato Prf is a member of the leucine-rich-repeat class of plant disease resistance genes and lies embedded within the Pto kinase gene cluster. Cell 86, 123-133.
21. Scofield, S.R., Tobias, C.M., Rathjen, J.P., Chang, J.H., Lavelle, D.T., Michelmore, R.W., and Staskawicz, B.J. (1996). Molecular basis of gene-for-gene specificity in bacterial speck disease of tomato. Science 274, 2063-2065.
22. Tang, X., Frederick, R.D., Zhou, J., Halterman, D.A., Jia, Y., and Martin, G.B. (1996). The avirulence protein AvrPto physically interacts with the Pto kinase. Science 274, 2060-2063.
23. Tanksley, S.D., Brommonschenkel, S., and Martin, G.B. (1996). Ptoh, an allele of Pto conferring resistance to Pseudomonas syringae pv. tomato (race 0) that is not associated with fenthion sensitivity. Tomato Genet. Coop. Rep. 46, 28-29.
24. Thomas, C.M., Jones, D.A., Parniske, M., Harrison, K., Balint-Kurti, P.J., Hatzixanthis, K., and Jones, J.D.G. (1997). Characterization of the tomato Cf-4 gene for resistance to Cladosporium fulvum identifies sequences that determine recognitional specificity in Cf-4 and Cf-9. Plant Cell 9, 2209-2224.
25. Van den Ackerveken, G., Marois, E., and Bonas, U. (1996). Recognition of the bacterial avirulence protein AvrBs3 occurs inside the host plant cell. Cell 87, 1307-1316.