Nuclear localization of β-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

American Journal of Physiology - Renal Physiology

Volumn 276, Issue 2 45-2, 1999, Pages

  Sorenson, Christine M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Actin; Adherens junctions; Renal multicystic disease; Catenin

Indexed keywords

ACTIN; ALPHA CATENIN; BETA CATENIN; PROTEIN BCL 2; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CELL INTERACTION; CELL NUCLEUS; CONTROLLED STUDY; KIDNEY POLYCYSTIC DISEASE; KIDNEY TUBULE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

EID: 0033034613     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1999.276.2.f210     Document Type: Article

References (23)

1. Avner, E. Epithelial polarity and differentiation in polycystic kidney disease. J. Cell Sci. 17: 217-222, 1993.
2. Barth, A. I. M., I. S. Nathke, and W. J. Nelson. Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr. Opin. Cell Biol. 9: 683-690, 1997.
3. Calvet, J. P. Polycystic kidney disease: primary extracellular matrix abnormality or defective cellular differentiation? Kidney Int. 43: 101-108, 1993.
4. Carone, F. A., R. Bacallo, and Y. S. Kanwar. Biology of disease: biology of polycystic kidney disease. Lab. Invest. 70: 437-448, 1994.
5. Chandler, D., A. K. El-Naggar, S. Brisbay, R. W. Redline, and T. J. McDonnell. Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: evidence for the contribution of bcl-2 expression to renal carcinogenesis. Hum. Pathol. 25: 789-796, 1994.
6. Farrow, S. N., and R. Brown. New members of the bcl-2 family and their protein partners. Curr. Opin. Genet. Dev. 6: 45-49, 1996.
7. Fick, G. M., and P. Gabow. Hereditary and acquired cystic disease of the kidney. Kidney Int. 46: 951-964, 1994.
8. Gabow, P. Polycystic kidney disease: clues to pathogenesis. Kidney Int. 40: 989-996, 1991.
9. Grantham, J. J. Polycystic kidney disease: neoplasia in disguise. Am. J. Kidney Dis. 15: 110-116, 1990.
10. Grantham, J. J. Fluid secretion, cellular proliferation, and the pathogenesis of renal epithelial cysts. J. Am. Soc. Nephrol. 3: 1843-1857, 1993.
11. Gumbiner, B. M. Carcinogenesis: a balance between β-catenin and APC. Curr. Biol. 7: R443-R446, 1997.
12. Hinck, L., I. S. Nathke, J. Papkoff, and W. J. Nelson. β-Catenin: a common target for the regulation of cell adhesion by Wnt-1 and Src signaling pathways. Trends Biochem. Sci. 19: 538-542, 1994.
13. Huber, O., C. Bierkamp, and R. Kemler. Cadherins and catenins in development. Curr. Opin. Cell Biol. 8: 685-691, 1996.
14. Piepenhagen, P. A., and W. J. Nelson. Differential expression of cell-cell and cell-substratum adhesion proteins along the kidney nephron. Am. J. Physiol. 269 (Cell Physiol. 38): C1443-C1449, 1995.
15. +-ATPase, ankyrin, fodrin and E-cadherin along the kidney nephron. Am. J. Physiol. 269 (Cell Physiol. 38): C1417-C1432, 1995.
16. Pollack, A. L., A. I. M. Barth, Y. Altschuler, W. J. Nelson, and K. E. Mostov. Dynamics of β-catenin interactions with APC protein regulate epithelial tubulogenesis. J. Cell Biol. 137: 1651-1662, 1997.
17. Sorenson, C. Life, death and kidneys: regulation of renal programmed cell death. Curr. Opin. Nephrol. Hypertens. 7: 5-12, 1998.
18. Sorenson, C. M., B. J. Padanilam, and M. R. Hammerman. Abnormal postpartum renal development and cystogenesis in the bcl-2 -/- mouse. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F184-F193, 1996.
19. Sorenson, C. M., S. A. Rogers, S. J. Korsmeyer, and M. R. Hammerman. Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F73-F81, 1995.
20. Valizadeh, A., A. J. Karayiannakis, I. El-Hariry, W. Kmiot, and M. Pignatelli. Expression of E-cadherin-associated molecules (α-, β-, and γ-catenins and p120) in colorectal polyps. Am. J. Pathol. 150: 1977-1984, 1997.
21. Veis, D. J., C. M. Sorenson, J. R. Shutter, and S. J. Korsmeyer. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys and hypopigmented hair. Cell 76: 777-779, 1994.
22. Welling, L. W., and J. J. Grantham. Cystic and developmental diseases of the kidney. In: The Kidney, edited by B. M. Brenner and F. C. Rector. Philadelphia PA: Sanders, 1991.
23. Wilson, P. D., and A. C. Sherwood. Tubulocystic epithelium. Kidney Int. 39: 450-463, 1991.