The 5' RNA terminus of spleen necrosis virus contains a novel posttranscriptional control element that facilitates human immunodeficiency virus Rev/RRE-independent gag production

Journal of Virology

Volumn 73, Issue 6, 1999, Pages 4847-4855

  Butsch, Melinda ^a,b   Hull, Stacey ^a,b   Wang, Yalai ^a   Roberts, Tiffiney M ^a,b   Boris Lawrie, Kathleen ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; REV PROTEIN; VIRUS PROTEIN; VIRUS RNA;

ARTICLE; BOVINE LEUKEMIA VIRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOBLOTTING; NONHUMAN; PLASMID; PRIORITY JOURNAL; RNA SPLICING; SPLEEN DISEASE; TISSUE NECROSIS; TRANSCRIPTION REGULATION; VIRUS GENOME;

EID: 0033034217     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.6.4847-4855.1999     Document Type: Article

References (38)

1. Afonina, E., M. Neumann, and G. N. Pavlakis. 1997. Preferential binding of poly (A)-binding protein 1 to an inhibitory RNA element in the human immunodeficiency virus type 1 gag mRNA. J. Biol. Chem. 272:2307-2311.
2. Arrigo, S. J., and I. S. Y. Chen. 1991. Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu-2 RNAs. Genes Dev. 5:808-819.
3. Benko, D. M., R. Robinson, L. Solomin, M. Melinni, B. K. Felber, and G. N. Pavlakis. 1990. Binding of trans-dominant mutant Rev-responsive element does not affect the fate of viral messenger RNA. New Biol. 2:1111-1122.
4. Bray, M., S. Prasad, J. W. Dubay, E. Hunter, K.-T. Jeang, D. Rekosh, and M.-L. Hammarskjöld. 1994. A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent. Proc. Natl. Acad. Sci. USA 91:1256-1260.
5. Boris-Lawrie, K., and H. M. Temin. 1995. Genetically simple derivatives of bovine leukemia virus can replicate independently of Tax and Rex. J. Virol. 69:1920-1924.
6. Boris-Lawrie, K., V. Altanerova, C. Altaner, L. Janglova, and H. M. Temin. 1997. Genetically simple BLV derivatives are infectious in vivo and induce anti-viral antibodies. J. Virol. 71:1514-1520.
7. Chang, D. D., and P. A. Sharp. 1989. Regulation by HIV Rev depends upon recognition of splice sites. Cell 59:789-795.
8. Cochrane, A. W., K. S. Jones, S. Beidas, P. J. Dillion, A. M. Skalka, and C. A. Rosen. 1991. Identification and characterization of intragenic sequences with repress human immunodeficiency virus structural gene expression. J. Virol. 45:5305-5313.
9. Cupelli, L., S. A. Okenquist, A. Trubetskoy, and J. Lenz. 1998. The secondary structure of the R region of a murine leukemia virus is important for stimulation of long terminal repeat-driven gene expression. J. Virol. 72: 7807-7814.
10. D'Agostino, D. M., B. K. Felber, J. E. Harrison, and G. N. Pavlakis. 1992. The rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs. Mol. Cell. Biol. 12:1375-1386.
11. Emerman, M., R. Vazeux, and K. Peden. 1989. The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization. Cell 57:1155-1165.
12. Ernest, R. K., M. Bray, D. Rekosh, and M.-L. Hammarskjöld. 1997. A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA. Mol. Cell. Biol. 17:135-144.
13. Felber, B. K., M. Hadzopoulou-Cladaras, C. Cladaras, T. Copeland, and G. N. Pavlakis. 1989. Rev protein of human immunodeficiency virus type 1 affects the stability and transport of viral mRNA. Proc. Natl. Acad. Sci. USA 84:1495-1499.
14. Grüter, P., C. Tabernero, C. von Kobbe, C. Schmitt, C. Saavedra, A. Bachi, M. Wilm, B. K. Felber, and E. Izaurralde. 1998. TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol. Cell 1:649-659.
15. Hadzopoulou-Cladaras, M., B. K. Felber, C. Cladaras, A. Athanassopoulos, A. Tse, and G. N. Pavlakis. 1989. The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region. J. Virol. 63:1265-1274.
16. Hammarskjöld, M. L., J. Heimer, B. Hammarskjöld, I. Sangwan, L. Albert, and D. Rekosh. 1989. Regulation of human immunodeficiency virus env expression by the rev gene product. J. Virol. 63:1959-1966.
17. Hammarskjöld, M. L., H. Li, D. Rekosh, and S. Prasad. 1994. Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron. J. Virol. 68:951-958.
18. Lawrence, J. B., A. W. Cochrane, C. V. Johnson, A. Perkins, and C. A. Rosen. 1991. The HIV-1 Rev protein: a model system for coupled RNA transport and translation. New Biol. 3:1220-1232.
19. Malim, M. H., J. Hauber, S.-Y. Le, J. V. Maizel, and B. R. Cullen. 1989. The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. Nature 339:254-257.
20. Malim, M. H., and B. R. Cullen. 1993. Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes. Mol. Cell. Biol. 13:6180-6189.
21. Maldarelli, F., M. A. Martin, and K. Strebel. 1991. Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation. J. Virol. 65:5732-5743.
22. McBride, M. S., and A. T. Panganiban. 1996. The human immunodeficiency virus type 1 encapsidation site is a multipartite RNA element composed of functional hairpin structures. J. Virol. 70:2963-2973.
23. Ogert, R. A., L. H. Lee, and K. L. Beemon. 1996. Avian retroviral RNA element promotes unspliced RNA accumulation in the cytoplasm. J. Virol. 70:3834-3843.
24. Rizvi, T. A., R. D. Schmidt, and K. A. Lew. 1997. Mason-Pfizer monkey virus (MPMV) constitutive transport element (CTE) functions in a position-dependent manner. Virology 236:118-129.
25. Schneider, R., M. Campbell, G. Nasioulas, B. K. Felber, and G. N. Pavlakis. 1997. Inactivation of the human immunodeficiency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation. J. Virol. 71:4892-4903.
26. Schoenberg, D. R., and K. S. Cunningham. 1999. Characterization of mRNA endonucleases. Methods Companion Methods Enzymol. 17:60-73.
27. Schwartz, S., B. K. Felder, and G. N. Pavlakis. 1992. Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. J. Virol. 66:150-159.
28. Schwartz, S., M. Campbell, G. Nasioulas, J. Harrison, B. K. Felber, and G. N. Pavlakis. 1992. Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression. J. Virol. 66:7176-7182.
29. Simpson, S. B., L. Zhang, R. C. Craven, and C. M. Stoltzfus. 1997. Rous sarcoma virus direct repeat cis elements exert effects at several points in the virus life cycle. J. Virol. 71:9150-9156.
30. gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles. J. Virol. 64:2743-2750.
31. Sonigo, P., C. Barker, E. Hunter, and S. Wain-Hobson. 1986. Nucleotide sequence of Mason-Pfizer monkey virus: an immunosuppressive D-type retrovirus. Cell 45:375-385.
32. Taberaero, C., A. S. Zolotukhin, A. Valentin, G. N. Pavlakis, and B. K. Felber, 1996. The posttranscriptional control element of the simian retrovirus type 1 forms an extensive RNA secondary structure necessary for its function. J. Virol. 70:5998-6011.
33. Tang, H., G. M. Gaietta, W. H. Fischer, M. H. Ellisman, and F. Wong-Staal. 1997. A cellular cofactor for the constitutive transport element of type D retrovirus. Science 276:1412-1415.
34. Tarun, S. Z., Jr., and A. B. Sachs. 1995. A common function for mRNA 5′ and 3′ ends in translation initiation in yeast. Genes Dev. 9:2997-3007.
35. von Gegerfelt, A., and B. K. Felber. 1997. Replacement of posttranscriptional regulation in SIVmac239 generated a Rev-independent infectious virus able to propagate in rhesus peripheral blood mononuclear cells. Virology 232: 291-299.
36. Wain-Hobson, S., P. Sonigo, O. Danos, S. Cole, and M. Alizon. 1985. Nucleotide sequence of the AIDS virus, LAV. Cell 40:9-17.
37. Wilhemsen, K. C., K. Eggleton, and H. M. Temin. 1984. Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus stain T and its cellular homolog, the proto-oncogene c-rel. J. Virol. 52:172-182.
38. Zolotukhin, A. S., A. Valentin, G. N. Pavlakis, and B. K. Felber. 1994. Continuous propagation of RRE(-) and RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian virus type 1 in human peripheral blood lymphocytes. J. Virol. 68:7944-7952.