Novel mycophenolic adenine bis(phosphonate)s as potent anticancer agents and inducers of cells differentiation

Nucleosides and Nucleotides

Volumn 18, Issue 4-5, 1999, Pages 927-932

  Pankiewicz, Krzysztof W ^a   Lesiak Watanabe, Krystyna ^a  

^a Division of Medicinal Chemistry   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; MYCOPHENOLIC ADENINE BIS(PHOSPHONATE); TIAZOFURIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL LINE; CELL STRAIN HL 60; CELL STRAIN K 562; CONFERENCE PAPER; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL;

EID: 0033030965     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/15257779908041601     Document Type: Conference Paper

References (16)

1. Wright, D.G.; Boosalis, M.S.; Waraska, K.; Oshry, L.J.; Weintraub, L.R.; Vosburgh, E. Anticnancer Res., 1996, 16, 3349-3351.
2. Tricot, G. and Weber, G. Anticancer Res., 1996, 16, 3341-3347.
3. Olah, E.; Csokay, B.; Prajda, N.; Kote-Jari, Z.; Yeh, Y.A.; Weber, G. Anticancer Res., 1996, 16, 2469-2477.
4. Weber, G.; Prajda, N.; Abonyi, M.; Look, K.Y.; Tricot, G.Anticancer Res., 1996, 16, 3313-3322
5. Kiguhi, K.; Collart, F.R.; Henning-Chubb, C.; Huberman. Exp. Cell Res., 1990, 187, 47-53.
6. Olah, E.; Natsumeda, Y.; Ikegami, T.; Kote, Z.; Horanyi, M.; Szelenyi, J.; Paulik, E.; Kremmer, T.; Hollan, S.R.; Sugar, J.; Weber, G. Proc. Natl. Acad. Sci., 1988, 85, 6533-6537.
7. Sidi, Y.; Panet, C.; Wasserman, L.; Cyjon, A.; Novogrodsky, A.; Nordenberg, J. Eur. J. Cancer Clin. Oncol., 1989, 25, 883-889.
8. Tsutani, H.; Inai, K.; Imamura, S.; Ueda, T.; Nakamura, T. Purine and Pyrimidine Metabolism in Man VIII, Sahota, A. and Taylor, M., eds, Plenum Press, 1995, 757-760.
9. Carr, S.F.; Papp, E.; Wu, J.C.; Natsumeda, Y. J. Biol. Chem., 1933, 268, 27286-27290.
10. Gebeyehu, G.; Marquez, V.E.; Kelly, J.A.; Cooney, D.A.; Jayaram, H.N.; Johns, D.G. J. Med. Chem., 1983, 26, 922-925.
11. Pankiewicz, K.W.; Zeidler, J.; Ciszewski, L.A.; Ellis Bell, J.; Goldstein, B.M.; Jayaram, H.N.; Watanabe, K.A. J. Med. Chem., 1993, 36, 1855-1859.
12. Joos, P.E.; Esmans, E.L.; Dommisse, R.A.; Van Dongen, W.; Lepoivre, J.A.; Balzarini, J.; De Clerq, E. Nucleosides & Nucleotides, 1991, 10, 883-894.
13. Krohn, K.; Heins, H.; Wielckens, K. J. Med. Chem., 1992, 35, 511-517.
14. Marquez, V.E.; Tseng, C.K.H.; Gebeyehu, G.; Cooney, D.A.; Ahluwalia, G.S.; Kelly, J.A.; Dalal, M.; Fuller, R.; Wilson, Y.A.; Johns, D.G. J. Med. Chem., 1986, 28, 1726-1731.
15. Lesiak, K.; Watanabe, K.A.; Majumdar, A.; Seidman, M.; Vanderveen, K.; Goldstein, B.M.; Pankiewicz, K.W. J. Med. Chem., 1997, 40, 2533-2538.
16. Lesiak, K.; Watanabe, K.A.; Majumdae, A.; Powell, J.; Seidman, M.; Vandeveen, K.; Goldstein, B.M.; Pankiewicz, K.W. J. Med. Chem., 1998, 41, 618-622.