Nitric oxide can function as either a killer molecule or an antiapoptotic effector in cardiomyocytes

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1450, Issue 3, 1999, Pages 406-413

  Stefanelli, Claudio ^a   Pignatti, Carla ^a   Tantini, Benedetta ^a   Stanić, Ivana ^a   Bonavita, Francesca ^a   Muscari, Claudio ^a   Guarnieri, Carlo ^a   Clo, Carlo ^b   Caldarera, Claudio M ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

Author keywords

Apoptosis; Caspase; N Acetylcysteine; Nitric oxide

Indexed keywords

CASPASE; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; S NITROSOGLUTATHIONE; SPERMINE; STAUROSPORINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CHICK EMBRYO; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; HEART MUSCLE CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; CHICK EMBRYO; GLUTATHIONE; HEART; NITRIC OXIDE; NITRO COMPOUNDS; PENICILLAMINE; STAUROSPORINE;

EID: 0033023630     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(99)00045-2     Document Type: Article

References (43)

1. Nicotera P., Brune B., Bagetta G. Nitric oxide: inducer or suppressor of apoptosis? Trends Pharmacol. Sci. 18:1997;189-190.
2. Kroncke K.D., Fehsel K., Bachofen V.K. Nitric oxide: cytotoxicity versus cytoprotection. How, why, when, and where? Nitric Oxide. 1:1997;107-120.
3. Dimmeler S., Zeiher A.M. Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide. Nitric Oxide. 1:1997;275-281.
4. Brune B., von Knethen A., Sandau K.B. Nitric oxide and its role in apoptosis. Eur. J. Pharmacol. 35:1998;261-272.
5. Bredt D.S., Snyder S.H. Nitric oxide: a physiologic messenger molecule. Annu. Rev. Biochem. 63:1994;175-195.
6. Stamler J.S. Redox signaling: nitrosylation and related target interaction of nitric oxide. Cell. 78:1994;931-993.
7. Stamler J.S., Hausladen A. Oxidative modifications in nitrosative stress. Nat. Struct. Biol. 5:1998;247-249.
8. Dimmeler S., Haendeler J., Nehls M., Zeiher A.M. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1β-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases. J. Exp. Med. 185:1997;601-607.
9. Li J., Billiar T.R., Talanian R.V., Kim Y.M. Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochem. Biophys. Res. Commun. 240:1997;419-424.
10. Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316.
11. Melino G., Bernassola F., Knight R.A., Corasaniti M.T., Nisticò G., Finazzi-Agrò A. S-Nitrosylation regulates apoptosis. Nature. 388:1997;432-433.
12. Ogura T., Tatemichi M., Esumi H. Nitric oxide inhibits CPP32-like activity under redox regulation. Biochem. Biophys. Res. Commun. 236:1997;365-369.
13. Haendeler J., Weiland U., Zeiher A.M., Dimmeler S. Effects of redox-related congeners of NO on apoptosis and caspase-3 activity. Nitric Oxide. 1:1997;282-293.
14. Mohr S., Zech B., Lapetina E.G., Brune B. Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide. Biochem. Biophys. Res. Commun. 238:1997;387-391.
15. Kim Y.M., Talanian R.V., Billiar T.R. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J. Biol. Chem. 272:1997;31138-31148.
16. Kim Y.M., Kim T.H., Seol D.W., Talanian R.V., Billiar T.R. Nitric oxide suppression of apoptosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release. J. Biol. Chem. 273:1998;31437-31441.
17. Longrois D.U., Bèzie Y., Perret C., Laurent S. Effects of exogenous and endogenous nitric oxide on the contractile function of cultured chick embryo ventricular myocytes. J. Mol. Cell. Cardiol. 29:1997;677-687.
18. Thornberry N.A., Rano T.A., Peterson E.P., Rasper D.M., Timkey T., Garcia-Calvo M., Houtzager V.M., Nordstrom P.A., Roy S., Vaillancourt J.P., Chapman K.T., Nicholson D.W. A combinatorial approach defines specificities of members of the caspase family and granzyme B. J. Biol. Chem. 272:1997;17907-17911.
19. Muscari C., Pappagallo M., Ferrari D., Giordano E., Capanni C., Caldarera C.M., Guarnieri C. Simultaneous detection of reduced and oxidized glutathione in tissues and mitochondria by capillary electrophoresis. J. Chromatogr. B Biomed. Appl. 707:1998;301-307.
20. Padgett C.M., Whorton A.R. Cellular responses to nitric oxide: role of protein S-thiolation/dethiolation. Arch. Biochem. Biophys. 358:1998;232-242.
21. Nishikawa M., Sato E.F., Kashiba M., Kuroki T., Utsumi K., Inoue M. Role of glutathione in nitric oxide-dependent regulation of energy metabolism in rat hepatoma cells. Hepatology. 27:1998;422-426.
22. Brune B., Mohr S., Messmer U.K. Protein thiol modification and apoptotic cell death as cGMP-independent nitric oxide (NO) signaling pathway. Rev. Physiol. Biochem. Pharmacol. 127:1996;1-30.
23. Burney S., Tamir S., Gal A., Tannenbaum S.R. A mechanistic analysis of nitric oxide-induced cellular toxicity. Nitric Oxide. 1:1997;130-144.
24. deRojas-Walker T., Tamir S., Ji H., Wishnok J.S., Tannenbaum S.R. Nitric oxide induces oxidative damage in addition to deamination in macrophage DNA. Chem. Res. Toxicol. 8:1995;473-477.
25. Salgo M.G., Bermudez E., Squadrito G.L., Pryor W.A. Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes. Arch. Biochem. Biophys. 322:1995;500-505.
26. Thomas S., Lowe J.E., Knowles R.G., Green I.C., Green M.H. Factors affecting the DNA damaging activity of superoxide and nitric oxide. Mutat. Res. 402:1998;77-84.
27. Clementi E., Brown G.C., Feelisch M., Moncada S. Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. Proc. Natl. Acad. Sci. USA. 95:1998;7631-7636.
28. Messmer U.K., Brune B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem. J. 319:1995;299-305.
29. Balakirev M.Y., Khramtsov V.V., Zimmer G. Modulation of the mitochondrial permeability transition by nitric oxide. Eur. J. Biochem. 246:1997;710-718.
30. Szabo C., Zingarelli B., O'Connor M., Salzman A.L. DNA strand breakage, activation of poly(ADP-ribose) synthetase and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxinitrite. Proc. Natl. Acad. Sci. USA. 93:1996;1753-1758.
31. Kim Y.M., de Vera M.E., Watkins S.C., Billiar T.R. Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-α-induced apoptosis by inducing heat shock protein 70 expression. J. Biol. Chem. 272:1997;1402-1411.
32. Genaro A.M., Hortelano S., Alvarez A., Martinez-A C., Boscà L. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J. Clin. Invest. 95:1995;1884-1890.
33. Sciorati C., Rovere P., Ferrarini M., Heltai S., Manfredi A.A., Clementi E. Autocrine nitric oxide modulates CD95-induced apoptosis in γδ T lymphocytes. J. Biol. Chem. 272:1997;23211-23215.
34. Lipton S.A., Chol Y.B., Pan Z.H., Lei S.Z., Chen H.S.V., Sucher N.J., Loscalzo J., Singel D.J., Stamler J.S. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature. 364:1993;626-632.
35. Schwarz M.A., Lazo J.S., Yalowich J.C., Allen W.P., Whitmore M., Bergonia H.A., Tzeng E., Billiar T.R., Robbins P.D., Lancaster J.R., Pitt B.R. Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide. Proc. Natl. Acad. Sci. USA. 92:1995;4452-4456.
36. Zhao Z., Francis C.E., Welch G., Loscalzo J., Ravid K. Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells. Biochim. Biophys. Acta. 1359:1997;143-152.
37. Yan C.Y.I., Greene L.A. Prevention of PC12 cell death by N-acetylcysteine requires activation of the RAS pathway. J. Neurosci. 18:1998;4042-4049.
38. Arnelle D.R., Day B.J., Stamler J.S. Diethyl dithiocarbamate-induced decomposition of S-nitrosothiols. Nitric Oxide. 1:1997;56-64.
39. Wink D.A., Cook J.A., Pacelli R., DeGraff W., Gamson J., Liebmann J., Krishna M.C., Mitchell J.B. The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection. Arch. Biochem. Biophys. 331:1996;241-248.
40. Miles A.M., Bohle D.S., Glassbrenner P.A., Hansert B., Wink D.A., Grisham M.B. Modulation of superoxide-dependent oxidation and hydroxylation reactions by nitric oxide. J. Biol. Chem. 271:1996;40-47.
41. Foresti R., Clark J.E., Green C.J., Motterlini R. Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. J. Biol. Chem. 272:1997;18411-18417.
42. van der Vliet A., 't Hoen P.A., Wong P.S., Bast A., Cross C.E. Formation of S-nitrosothiols via direct nucleophilic nitrosation of thiols by peroxynitrite with elimination of hydrogen peroxide. J. Biol. Chem. 273:1998;30255-30262.
43. Wong P.S., Hyun J., Fukuto J.M., Shirota F.N., DeMaster E.G., Shoeman D.W., Nagasawa H.T. Reaction between S-nitrosothiols and thiols: generation of nitroxyl (HNO) and subsequent chemistry. Biochemistry. 37:1998;5362-5371.