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Volumn 151, Issue 6, 1999, Pages 686-693

Correlation between unirradiated cell TP53 protein levels and radiosensitivity in MOLT-4 cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DNA; MESSENGER RNA; PROTEIN P53;

EID: 0033022344     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3580207     Document Type: Article
Times cited : (18)

References (57)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • J. F. R. Kerr, A. H. Wyllie and A. R. Currie, Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257 (1972).
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 2
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • A. H. Wyllie, Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-556 (1980).
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 3
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • E. White, Life, death, and the pursuit of apoptosis. Genes Dev. 10, 1-15 (1996).
    • (1996) Genes Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 4
  • 5
    • 0027479655 scopus 로고
    • Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
    • D. G. Brown, X-M. Sun and G. M. Cohen, Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268, 3037-3039 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 3037-3039
    • Brown, D.G.1    Sun, X.-M.2    Cohen, G.M.3
  • 6
    • 0027942467 scopus 로고
    • X-ray-induced cell death: Apoptosis and necrosis
    • H. Nakano and K. Shinohara, X-ray-induced cell death: Apoptosis and necrosis. Radiat. Res. 140, 1-9 (1994).
    • (1994) Radiat. Res. , vol.140 , pp. 1-9
    • Nakano, H.1    Shinohara, K.2
  • 7
    • 0028072523 scopus 로고
    • DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
    • A. Strasser, A. W. Harris, T. Jacks and S. Cory, DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell 79, 329-339 (1994).
    • (1994) Cell , vol.79 , pp. 329-339
    • Strasser, A.1    Harris, A.W.2    Jacks, T.3    Cory, S.4
  • 12
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • S. W. Lowe, E. M. Schmitt, S. W. Smith, B. A. Osborne and T. Jacks, p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362, 847-849 (1993).
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 13
    • 0027285380 scopus 로고
    • p53 mutations increase resistance to ionizing radiation
    • J. M. Lee and A. Bernstein, p53 mutations increase resistance to ionizing radiation. Proc. Natl. Acad. Sci. USA 90, 5742-5746 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 16
    • 0027500246 scopus 로고
    • Induction of nuclear accumulation of the tumour-suppressor protein p53 by DNA-damaging agents
    • M. Fritsche, C. Haessler and G. Brandner, Induction of nuclear accumulation of the tumour-suppressor protein p53 by DNA-damaging agents. Oncogene 8, 307-318 (1993).
    • (1993) Oncogene , vol.8 , pp. 307-318
    • Fritsche, M.1    Haessler, C.2    Brandner, G.3
  • 19
    • 0028944890 scopus 로고
    • Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines
    • F. Xia, X. Wang, Y-H. Wang, N-M. Tsang, D. W. Yandell, K. T. Kelsey and H. L. Liber, Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines. Cancer Res. 55, 12-15 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 12-15
    • Xia, F.1    Wang, X.2    Wang, Y.-H.3    Tsang, N.-M.4    Yandell, D.W.5    Kelsey, K.T.6    Liber, H.L.7
  • 20
    • 0019830333 scopus 로고
    • Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells
    • M. Oren, W. Maltzman and A. J. Levine, Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol. Cell Biol. 1, 101-110 (1981).
    • (1981) Mol. Cell Biol. , vol.1 , pp. 101-110
    • Oren, M.1    Maltzman, W.2    Levine, A.J.3
  • 21
    • 0031015044 scopus 로고    scopus 로고
    • Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation
    • C. G. Maki and P. M. Howley, Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol. Cell. Biol. 17, 355-363 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 355-363
    • Maki, C.G.1    Howley, P.M.2
  • 22
    • 0015394127 scopus 로고
    • Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes
    • J. Minowada, T. Ohnuma and G. E. Moore, Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes. J. Natl. Cancer Inst. 49, 891-895 (1972).
    • (1972) J. Natl. Cancer Inst. , vol.49 , pp. 891-895
    • Minowada, J.1    Ohnuma, T.2    Moore, G.E.3
  • 23
    • 0016211705 scopus 로고
    • In vitro preferential effect of irradiation on cultured T lymphoid cell line
    • T. Han, J. L. Pauly and J. Minowada, In vitro preferential effect of irradiation on cultured T lymphoid cell line. Clin. Exp. Immunol. 17, 455-462 (1974).
    • (1974) Clin. Exp. Immunol. , vol.17 , pp. 455-462
    • Han, T.1    Pauly, J.L.2    Minowada, J.3
  • 24
    • 0018614092 scopus 로고
    • +-dependent amino acid transport in human T (Molt-4) and human B (RPMI 1788) lymphoid cells
    • +-dependent amino acid transport in human T (Molt-4) and human B (RPMI 1788) lymphoid cells. Radiat. Res. 80, 512-522 (1979).
    • (1979) Radiat. Res. , vol.80 , pp. 512-522
    • Kwock, L.1    Lin, P.-S.2    Ciborowski, L.3
  • 26
    • 0027437289 scopus 로고
    • Interphase death and reproductive death in X-irradiated MOLT-4 cells
    • K. Shinohara and H. Nakano, Interphase death and reproductive death in X-irradiated MOLT-4 cells. Radiat. Res. 135, 197-205 (1993).
    • (1993) Radiat. Res. , vol.135 , pp. 197-205
    • Shinohara, K.1    Nakano, H.2
  • 27
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • U. K. Laemmli, Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970).
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 28
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • H. Towbin, T. Staehelin and J. Gordon, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354 (1979).
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 29
    • 0023277545 scopus 로고
    • Single-step of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • P. Chomczynski and N. Sacchi, Single-step of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159 (1987).
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 30
    • 0024492086 scopus 로고
    • Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures
    • C. A. Smith, G. T. Williams, R. Kingston, E. J. Jenkinson and J. J. T. Owen, Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337, 181-184 (1989).
    • (1989) Nature , vol.337 , pp. 181-184
    • Smith, C.A.1    Williams, G.T.2    Kingston, R.3    Jenkinson, E.J.4    Owen, J.J.T.5
  • 31
    • 0023756451 scopus 로고
    • Immunophenotypic and cytogenetic analysis of Molt-3 and Molt-4: Human T-lymphoid cell lines with rearrangement of chromosome 7
    • J. M. Greenberg, R. Gonzalez-Sarmiento, D. C. Arthur, C. W. Wikowski, B. J. Streifel and H. Kersey, Immunophenotypic and cytogenetic analysis of Molt-3 and Molt-4: Human T-lymphoid cell lines with rearrangement of chromosome 7. Blood 72, 1755-1760 (1988).
    • (1988) Blood , vol.72 , pp. 1755-1760
    • Greenberg, J.M.1    Gonzalez-Sarmiento, R.2    Arthur, D.C.3    Wikowski, C.W.4    Streifel, B.J.5    Kersey, H.6
  • 32
    • 0028990145 scopus 로고
    • 1 arrest in two closely related human lymphoblast cell lines that differ in p53 status
    • 1 arrest in two closely related human lymphoblast cell lines that differ in p53 status. J. Biol. Chem. 270, 11033-11036 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 11033-11036
    • Little, J.B.1    Nagasawa, H.2    Keng, P.C.3    Yu, Y.4    Li, C.-Y.5
  • 33
    • 0028986587 scopus 로고
    • The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status
    • W. Zhen, C. M. Denault, K. Loviscek, S. Walter, L. Geng and A. T. M. Vaughan, The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status. Mutat. Res. 346, 85-92 (1995).
    • (1995) Mutat. Res. , vol.346 , pp. 85-92
    • Zhen, W.1    Denault, C.M.2    Loviscek, K.3    Walter, S.4    Geng, L.5    Vaughan, A.T.M.6
  • 35
    • 0028071555 scopus 로고
    • Mutation in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • M. S. Greenblatt, W. P. Bennett, M. Hollstein and C. C. Harris, Mutation in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res. 54, 4855-4878 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 36
    • 0025076728 scopus 로고
    • Frequent mutation in the p53 tumor suppressor gene in human leukemia T-cell lines
    • J. Cheng and M. Haas, Frequent mutation in the p53 tumor suppressor gene in human leukemia T-cell lines. Mol. Cell. Biol. 10, 5502-5509 (1990).
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5502-5509
    • Cheng, J.1    Haas, M.2
  • 37
    • 0027426737 scopus 로고
    • Alternative splicing of the p53 tumor suppressor gene in the Molt-4 T-lymphoblastic leukemia cell line
    • V. T. K. Chow, H. H. Quek and E. P. C. Tock, Alternative splicing of the p53 tumor suppressor gene in the Molt-4 T-lymphoblastic leukemia cell line. Cancer Lett. 73, 141-148 (1993).
    • (1993) Cancer Lett. , vol.73 , pp. 141-148
    • Chow, V.T.K.1    Quek, H.H.2    Tock, E.P.C.3
  • 38
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • E. Yonish-Rouach, D. Resnitzky, J. Lotem, L. Sachs, A. Kimchi and M. Oren, Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352, 345-347 (1991).
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 39
    • 0026523778 scopus 로고
    • Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line
    • P. Shaw, R. Bovey, S. Tardy, R. Sahli, B. Sordat and J. Costa, Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc. Natl. Acad. Sci. USA 89, 4495-4499 (1992).
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4495-4499
    • Shaw, P.1    Bovey, R.2    Tardy, S.3    Sahli, R.4    Sordat, B.5    Costa, J.6
  • 40
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • M. Scheffner, J. M. Huibregtse, R. D. Vierstra and P. M. Howly, The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75, 495-505 (1993).
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howly, P.M.4
  • 41
    • 0029952441 scopus 로고    scopus 로고
    • In vivo ubiquitination and proteasome-mediated degradation of p53
    • C. G. Maki, J. M. Huibregtse and P. M. Howly, In vivo ubiquitination and proteasome-mediated degradation of p53. Cancer Res. 56, 2649-2654 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 2649-2654
    • Maki, C.G.1    Huibregtse, J.M.2    Howly, P.M.3
  • 43
    • 0030962262 scopus 로고    scopus 로고
    • p53-dependent induction of apoptosis by proteasome inhibitors
    • U. G. Lopes, P. Erhardt, R. Yao and G. M. Cooper, p53-dependent induction of apoptosis by proteasome inhibitors. J. Biol. Chem. 272, 12893-12896 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 12893-12896
    • Lopes, U.G.1    Erhardt, P.2    Yao, R.3    Cooper, G.M.4
  • 44
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Y. Haupt, R. Maya, A. Kazaz and M. Oren, Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299 (1997).
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 45
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • M. H. G. Kubbutat, S. N. Jones and K. H. Vousden, Regulation of p53 stability by Mdm2. Nature 387, 299-303 (1997).
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.G.1    Jones, S.N.2    Vousden, K.H.3
  • 46
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumour suppressor p53
    • R. Honda, H. Tanaka and H. Yasuda, Oncoprotein MDM2 is a ubiquitin ligase E3 for tumour suppressor p53. FEBS Lett. 420, 25-27 (1997).
    • (1997) FEBS Lett. , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 47
    • 0027459198 scopus 로고
    • MDM2 expression is induced by wild type p53 activity
    • Y. Break, T. Juven, R. Haffner and M. Oren, MDM2 expression is induced by wild type p53 activity. EMBO J. 12, 461-468 (1993).
    • (1993) EMBO J. , vol.12 , pp. 461-468
    • Break, Y.1    Juven, T.2    Haffner, R.3    Oren, M.4
  • 48
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • J. Momand, G. P. Zambetti, D. C. Olson, D. George and A. J. Levine, The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69, 1237-1245 (1992).
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 49
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • S-Y. Shieh, M. Ikeda, Y. Taya and C. Prives, DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334 (1997).
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.-Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 53
    • 0025751550 scopus 로고
    • bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • C. L. Sentman, J. R. Shutter, D. Hockenbery, O. Kanagawa and S. J. Korsmeyer, bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67, 879-888 (1991).
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 54
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Z. N. Oltvai, C. L. Milliman and S. J. Korsmeyer, Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619 (1993).
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 55
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • T. Miyashita and J. C. Reed, Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299 (1995).
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 57
    • 0029821651 scopus 로고    scopus 로고
    • Dual roles of ATM in the cellular response to radiation and in cell growth control
    • Y. Xu and D. Baltimore, Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes Dev. 10, 2401-2410 (1996).
    • (1996) Genes Dev. , vol.10 , pp. 2401-2410
    • Xu, Y.1    Baltimore, D.2


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