Immunoreactive interleukin 4 and interferon-γ expression by type II alveolar epithelial cells in interstitial lung disease

Journal of Pathology

Volumn 187, Issue 4, 1999, Pages 475-480

  Wallace, W A H ^a,b   Howie, S E M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b NORTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Cryptogenic fibrosing alveolitis; Cytokines; Extrinsic allergic alveolitis; Interferon ; Interleukin 4; Pulmonary fibrosis; Sarcoidosis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4;

ADULT; AGED; ALLERGIC PNEUMONITIS; ARTICLE; CLINICAL ARTICLE; CYTOKINE PRODUCTION; FEMALE; FIBROSING ALVEOLITIS; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INTERSTITIAL LUNG DISEASE; LUNG ALVEOLUS CELL TYPE 2; LUNG BIOPSY; LUNG SARCOIDOSIS; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION;

AGED; ALVEOLITIS, EXTRINSIC ALLERGIC; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; INTERFERON TYPE II; INTERLEUKIN-4; LUNG DISEASES, INTERSTITIAL; MALE; MIDDLE AGED; PULMONARY ALVEOLI; PULMONARY FIBROSIS; RNA, MESSENGER; SARCOIDOSIS, PULMONARY;

EID: 0033021135     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199903)187:4<475::AID-PATH268>3.0.CO;2-N     Document Type: Article

References (34)

1. Wallace WAH, Lamb D. Cryptogenic fibrosing alveolitis: a clinico-pathological entity. Curr Diagn Pathol 1996; 3: 27-34.
2. Kradin RL, Divertie MB, Colvin RB, et al. Usual interstitial pneumonitis is a T cell alveolitis. Clin Immunol Immuno-pathol 1986; 40: 224-235.
3. Wallace WAH, Howie SEM, Krajewski AS, Lamb D. The immunological architecture of B lymphocyte aggregates in cryptogenic fibrosing alveolitis. J Pathol 1996; 178: 323-329.
4. Wallace WAH, Ramage EA, Lamb D, Howie SEM. A type 2 (Th2 like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis. Clin Exp Immunol 1995; 101: 436-441.
5. Mosmann TR, Cherwinski H, Bond MW, Gieldin MA, Coffman RL. Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136: 2348-2357.
6. Romagnani S, Human Th1 and Th2 subsets: doubt no more. Immunol Today 1991; 12: 256-257.
7. Pfeffer LM, Murphy JS, Tamm I. Interferon effects on the growth and division of human fibroblasts. Exp Cell Res 1979; 121: 111-120.
8. Duncan MR, Berman B. Gamma interferon is the lymphokine and β interferon is the monokine responsible for the inhibition of fibroblast collagen production and late but not early fibroblast proliferation. J Exp Med 1985; 112: 516-527.
9. Sempowski GD, Beckmann MP, Derdak S, Phipps RP. Subsets of murine lung fibroblasts express membrane-bound and soluble IL4 receptors. J Immunol 1994; 152: 3606-3614.
10. Prior C, Haslam PL. In vivo and in vitro production of interferon-gamma in fibrosing interstitial lung diseases. Clin Exp Immunol 1992; 88: 280-287.
11. Elias JA, Freundlich B, Kern JA, Rosenbloom J. Cytokine networks in the regulation of inflammation and fibrosis in the lung. Chest 1990; 97: 1439-1445.
12. Sheppard MN, Harrison NK. Lung injury, inflammatory mediators and fibroblast activation in fibrosing alveolitis. Thorax 1992; 47: 1064-1074.
13. Gauldie J, Jordana M, Cox G. Cytokines and pulmonary fibrosis. Thorax 1993; 48: 931-935.
14. Antoniades HN, Bravo MA, Avila RE, et al. Platelet-derived growth factor in idiopathic pulmonary fibrosis. J Clin Invest 1990; 86: 1055-1064.
15. Piquet PF, Ribaux C, Karpuz V, Grau GE, Kapanci Y. Expression and localisation of tumour necrosis factor-α and its mRNA in idiopathic pulmonary fibrosis. Am J Pathol 1993; 143: 651-655.
16. 1 in the lungs of patients with systemic sclerosis, cryptogenic fibrosing alveolitis and other lung disorders. Histopathology 1994; 24: 145-150.
17. Iyonaga K, Motohiro T, Saita N, et al. Monocyte chemoattractant protein-1 in idiopathic pulmonary fibrosis and other interstitial lung diseases. Hum Pathol 1994; 25: 455-463.
18. Howie SEM, Aldridge RD, McVittie E, Thornton E, Ramage E, Hunter JAA. A non-radiolabelled in situ hybridisation method for the detection of epidermal cytokine mRNA. Exp Dermatol 1992; 1: 230-235.
19. Howie SEM, Aldridge RD, McVittie E, Forsey RJ, Sands C, Hunter JAA. Epidermal keratinocyte production of interferon-γ immunoreactive protein and mRNA is an early event in allergic contact dermatitis. J Invest Dermatol 1996; 106: 1218-1223.
20. McKay IA, Leigh IM. Epidermal cytokines and their roles in cutaneous wound healing. Br J Dermatol 1991; 124: 513-518.
21. Katzenstein AA, Askin FB (eds). Chapters in Surgical Pathology of Non-neoplastic Lung Disease. Philadephia: W. B. Saunders, 1990.
22. Turner-Warwick M, Burrows B, Johnson A. Cryptogenic fibrosing alveolitis: response to corticosteroid therapy and survival. Thorax 1980; 35: 593-599.
23. Sarno M, Haselton PS, Spiteri MA. Sarcoidosis. In: Haselton PS, ed. Spencer's Pathology of the Lung. 5th edn. New York: McGraw-Hill, 1996; 507-535.
24. Haselton PS. Hypersensitivity pneumonitis (extrinsic allergic alveolitis). In: Haselton PS, ed. Spencer's Pathology of the Lung. 5th edn. New York: McGraw-Hill, 1996; 433-459.
25. Carnochan FM, Walker WS, Cameron EWJ. Efficacy of video assisted lung biopsy: an historical comparison with open lung biopsy. Thorax 1994; 49: 361-363.
26. Cattoretti G, Becker MHG, Key G, et al. Monoclonal Ab against recombinant parts of the Ki67 antigen (MIB-1 and MIB-3) detects proliferating cells in microwave processed formalin fixed paraffin sections. J Pathol 1992; 168: 357-363.
27. Mason RJ, Williams MC Alveolar type II cells. In: Crystal RG, West JB, eds. The Lung: Scientific Foundations. New York: Raven Press, 1995: 235-246.
28. Wallace WAH, Howie SEM, Lamb D, Salter DM. Tenascin immunoreactivity in cryptogenic fibrosing alveolitis. J Pathol 1995; 175: 415-420.
29. Mackie EJ, Halfter W, Liverani D. Induction of tenascin in healing wounds. J Cell Biol 1988; 107: 2757-2767.
30. Prior C, Knight RA, Herold M, Ott G, Spiteri MA. Pulmonary sarcoidosis: patterns of cytokine release in vitro. Eur Respir J 1996; 9: 47-53.
31. Gudmundsson G, Hunninghake GW. Interferon-gamma is necessary for the expression of hypersensitivity pneumonitis. J Clin Invest 1997; 99: 2386-2390.
32. Jeyalakshmi G, Giri SN. Molecular mechanisms of antifibrotic effect of interferon-gamma in bleomycin mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expression. Exp Lung Res 1995; 21: 791-808.
33. Tang ML, Varigos G, Kemp AS. Reduced interferon-gamma (IFN-gamma) secretion with increased IFN-gamma mRNA expression in atopic dermatitis: evidence for a post-transcriptional defect. Clin Exp Immunol 1994; 97: 483-489.
34. Young HA, Ghosh P. Molecular regulation of cytokine gene expression: interferon-gamma as a model system. Prog Nucleic Acid Res Mol Biol 1997; 76: 109-127.