Pulmonary sarcoidosis: Patterns of cytokine release in vitro

European Respiratory Journal

Volumn 9, Issue 1, 1996, Pages 47-53

  Prior, C ^a   Knight, R A ^b   Herold, M ^a   Ott, G ^a   Spiteri, M A ^c  

^a UNIVERSITY HOSPITAL INNSBRUCK   (Austria)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c KEELE UNIVERSITY   (United Kingdom)

Author keywords

Bronchoalveolar lavage; Cytokine production; Peripheral blood; Sarcoidosis

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; NEOPTERIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BRONCHUS SECRETION; CELL CULTURE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG SARCOIDOSIS; MALE; NEUTROPHIL; PRIORITY JOURNAL; SMOKING;

ADULT; AGED; BIOPTERIN; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CYTOKINES; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LUNG; MALE; MIDDLE AGED; NEOPTERIN; SARCOIDOSIS, PULMONARY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030071009     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.96.09010047     Document Type: Article

References (43)

1. Thomas PD, Hunninghake GW. Current concepts of the pathogenesis of sarcoidosis. Am Rev Respir Dis 1987; 135: 747-760.
2. Spiteri MA, Poulter LW, James DG. The macrophage in sarcoid granuloma formation. Sarcoidosis 1989; 6: 12-14.
3. Hunninghake GW. Release of interleukin-1 by alveolar macrophages of patients with active pulmonary sarcoidosis. Am Rev Respir Dis 1984; 129: 569-572.
4. Yamaguchi E, Okazaki N, Tsuneta Y, Abe S, Terai T, Kawakami Y. Interleukins in pulmonary sarcoidosis: dissociative correlations of lung interleukins-1 and -2 with the intensity of alveolitis. Am Rev Respir Dis 1988; 138: 645-651.
5. Strausz J, Männel DN, Pfeifer S, Borkowski A, Ferlinz R, Müller-Quernheim J. Spontaneous monokine release by alveolar macrophages in chronic sarcoidosis. Int Arch Allergy Appl Immunol 1991; 96: 68-75.
6. Baughman RP, Strohofer SA, Buchsbaum J, Lower EE. Release of tumor necrosis factor by alveolar macrophages of patients with sarcoidosis. J Lab Clin Med 1990; 115: 36-42.
7. Steffen M, Petersen J, Oldings M, et al. Increased secretion of tumor necrosis factor-α, interleukin-1β, and interleukin-6 by alveolar macrophages from patients with sarcoidosis. J Allergy Clin Immunol 1993; 91: 939-949.
8. Sahashi K, Ina Y, Takada K, Sato T, Yamamoto M, Morishita M. Significance of interleukin-6 in patients with sarcoidosis. Chest 1994; 106: 156-160.
9. Enthammer C, Zambello R, Trentin L, et al. Synthesis and release of granulocyte-macrophage colony-stimulating factor by alveolar macrophages of patients with sarcoidosis. Sarcoidosis 1993; 10: 147-148.
10. Prior C, Haslam PL. Increased levels of serum gamma-interferon in pulmonary sarcoidosis and relationship with response to corticosteroid therapy. Am Rev Respir Dis 1991; 143: 53-60.
11. Spiteri MA, Clarke SW, Poulter LW. Alveolar macrophages that suppress T-cell responses may be crucial to the pathogenetic outcome of pulmonary sarcoidosis. Eur Respir J 1992; 5: 394-403.
12. Moseley PL, Hemken C, Monick M, Nugent K, Hunninghake GW. Interferon and growth factor activity for human lung fibroblasts. Chest 1986; 89: 657-662.
13. Robinson BWS, McLemore TL, Crystal RG. Gamma-interferon is spontaneously released by alveolar macrophages and lung T-lymphocytes in patients with pulmonary sarcoidosis. J Clin Invest 1985; 75: 1488-1495.
14. Pinkston P, Bitterman PB, Crystal RG. Spontaneous release of interleukin-2 by lung T-lymphocytes in active pulmonary sarcoidosis. N Engl J Med 1983; 308: 793-800.
15. de Shazo RD, Banks DE, Diem JE, et al. Bronchoalveolar lavage cell-lymphocyte interactions in normal nonsmokers and smokers. Am Rev Respir Dis 1983; 127; 545-548.
16. Hughes DA, Haslam PL, Townsend PJ, Turner-Warwick M. Numerical and functional alterations in circulatory lymphocytes in cigarette smokers. Clin Exp Immunol 1985; 61: 459-466.
17. Cotes JE. In: Lung Function. Oxford, Blackwell Scientific Publications, 1979.
18. Forche G, Stadlober E, Harnoncourt K. Neue spirometrische Bezugswerte für Kinder, Jugendliche und Erwachsene. Öst Ärzteztg 1988; 43: 40-42.
19. Wewers MD, Saltini C, Selers S, et al. Evaluation of alveolar macrophages in normals and individuals with active pulmonary sarcoidosis for the spontaneous expression of the interleukin-1β gene. Cell Immunol 1987; 107: 479-488.
20. Kern JA, Lamb RJ, Reed JC, Elias JA, Daniele RP. Interleukin-1β gene expression in human monocytes and alveolar macrophages from normal subjects and patients with sarcoidosis. Am Rev Respir Dis 1988; 137: 1180-1184.
21. Bost TW, Riches DWH, Schumacher B, et al. Alveolar macrophages from patients with beryllium disease and sarcoidosis express increased levels of mRNA for tumor necrosis factor-α and interleukin-6 but not interleukin-1β. Am J Respir Cell Mol Biol 1994; 10: 506-513.
22. Spatafora M, Merendino A, Chiappara G, et al. Lung compartmentalization of increased TNF releasing ability by mononuclear phagocytes in pulmonary sarcoidosis. Chest 1989; 96: 542-549.
23. Hudspith BN, Flint KC, Geraint-James D, Brostoff J, Johnson NMcI. Lack of immune deficiency in sarcoidosis: compartmentalisation of the immune response. Thorax 1987; 42: 250-255.
24. Müller-Quernheim J, Pfeifer S, Männel D, Strausz J, Ferlinz R. Lung-restricted activation of the alveolar macrophage/monocyte system in pulmonary sarcoidosis. Am Rev Respir Dis 1992; 145: 187-192.
25. Homolka J, Müller-Quernheim J. Increased interleukin-6 production by bronchoalveolar lavage cells in patients with active sarcoidosis. Lung 1993; 171: 173-183.
26. Miyachi A, Noda M, Ina Y, et al. Tumor necrosis factor in granulomatous lung diseases. Sarcoidosis 1989; 6: 80.
27. Kanegasaki S, Homma JY, Homma H, Washizaki M. Enhanced chemiluminescence response of phagocytosing monocytes from sarcoidosis patients. Int Arch Allergy Appl Immunol 1981; 64: 72-79.
28. Prior C, Ott G, Spiteri M, Rotondetto S, Thaler J. Increased intracellular interleukin-1β in alveolar macrophages of workers exposed to inorganic dusts. Eur Respir J 1994; 7: 426s.
29. 2 release, alveolitis, and disease severity in sarcoidosis. Chest 1993; 103: 832-838.
30. Arnaout MA, Wang EA, Clark SC, Sieff CA. Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes, J Clin Invest 1986; 78: 597-601.
31. Devereux S, Linch DC, Campos Costa D, Spittle MF, Jelliffe AM. Transient leukopenia induced by granulocyte-macrophage colony-stimulating factor. Lancet 1987; ii: 1523-1524.
32. Limb GA, Hamblin AS, Wolstencroft RA, Dumonde DC. Selective upregulation of human granulocyte integrins and complement receptor 1 by cytokines. Immunology 1991; 74: 696-702.
33. Dinarello CA. Interleukin-1 and interleukin-1 antagonism. Blood 1991; 77: 1627-1652.
34. Sisson SD, Dinarello CA. Production of interleukin-1 a, interleukin-1β and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor. Blood 1988; 72: 1368-1374.
35. Spiteri MA, Prior C, Herold M, Knight RA, Clarke SW, Chung FK. Profile of specific cytokine release from bronchoalveolar lavage (BAL) cells in bronchial asthma: an enhancement of IL-1, IL-6, TNF-α and GM-CSF. Am Rev Respir Dis 1992; 145: A239.
36. Kasahara K, Kobayashi K, Shikama Y, et al. The role of monokines in granuloma formation in mice: the ability of interleukin-1 and tumor necrosis factor-α to induce lung granulomas. Clin Immunol Immunopathol 1989; 51: 419-425
37. Kunkel SL, Chensue SW, Strieter RM, Lynch JP, Remick DG. Cellular and molecular aspects of granulomatous inflammation. Am J Respir Cell Mol Biol 1989; 1: 439-447.
38. Elias JA, Kotloff R. Mononuclear cell-fibroblast interactions in the human lung. Chest 1991; 99: 73s-79s.
39. Itoh A, Yamaguchi E, Kuzumaki N, et al. Expression of granulocyte-macrophage colony-stimulating factor mRNA by inflammatory cells in the sarcoid lung. Am J Respir Cell Mol Biol 1990; 3: 245-249.
40. Huber C, Batchelor R, Fuchs D, et al. Immune response-associated production of neopterin: release from macrophages primarily under control of interferon-γ. J Exp Med 1984; 160: 310-316
41. Holter JF, Li W, Kataria YP. Kveim-like granulomagenic factor in sarcoid autologous bronchoalveolar lavage cells correlates with lavage fluid monokines: interleukin-1β, tumor necrosis factor-α and interleukin-6. Am J Respir Crit Care Med 1994; 149: A610.
42. Prior C, Haslam PL. In vivo levels and in vitro production of interferon-γ in fibrosing interstitial lung diseases. Clin Exp Immunol 1992; 88: 280-287.
43. Consensus Conference: Activity of Sarcoidosis. Third WASOG meeting, Los Angeles, USA, September 8-11, 1993. Eur Respir J 1994; 7: 624-627.