Epidermal keratinocyte production of interferon-γ immunoreactive protein and mRNA is an early event in allergic contact dermatitis

Journal of Investigative Dermatology

Volumn 106, Issue 6, 1996, Pages 1218-1223

  Howie, Sarah E M ^a   Aldridge, Roger D ^a   McVittie, Eva ^a   Forsey, Rosalyn J ^a   Sands, Catherine ^a   Hunter, John A A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

allergy; cytokines; immunohistochemistry; in situ hybridization

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 8; MESSENGER RNA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; PRIORITY JOURNAL; SKIN ALLERGY;

EID: 0029884452     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12348507     Document Type: Article

References (27)

1. Barker JNWN, Karabin GD, Stoof TJ, Sarma VJ, Dixit VM, Nickoloff BJ: Detection of interferon-gamma mRNA in psoriatic epidermis by polymerase chain reaction. J Dermatol Sci 2:106-111, 1991
2. Barker JNWN, Sarma V, Dixit V, Nickoloff BJ: Marked synergism between tumor necrosis factor-α and interferon-γ in regulation of keratinocyte derived adhesion molecules and chemotactic factors. J Clin Invest 85:605-608, 1990
3. Basham TY, Nickoloff BJ, Merigan TC, Morhenn VB: Recombinant gamma interferon induces HLA-DR on cultured human keratinocytes. Br J Dermatol 122:451-458, 1990
4. Cher DJ, Mosmann TR: Two types of murine helper T cell clone II. Delayed-type hypersensitivity is mediated by Th1 clones. J Immunol 138:3688-3694, 1987
5. Chu CQ, Field M, Andrew E, Haskard D, Feldmann M, Maini RN; Detection of cytokines at the site of tuberculin-induced delayed-type hypersensitivity in man. Clin Exp Immunol 90:522-529, 1992
6. Cockfield SM, Ramassar V, Noujaim J, van der Meide PH, Halloran PF: Regulation of IFN-γ expression in vivo: IFN-γ up-regulates expression of its mRNA in normal and lipopolysaccharide stimulated mice. J Immunol 150:717-725, 1993
7. Dallman MJ, Montgomery RA, Larsen CP, Wanders A, Wells A: Cytokine gene expression: analysis using Northern blotting, polymerase chain reaction and in situ hybridization. Immunol Rev 119:163-179, 1991
8. Dayton MA, Knobloch TJ, Benjamin D: Human B cell lines express the interferon gamma gene. Cytokine 4:454-460, 1992
9. DeSousa M, Parrott DMV: Induction and recall in contact sensitivity. J Exp Med 130:671-678, 1969
10. Enk AH, Katz SI: Early molecular events in the induction phase of contact sensitivity. Proc Natl Acad Sci USA 89:1398-1402, 1992
11. Fregert S: Manual of Contact Dermatitis. Munksgaard, Copenhagen, 1981, pp 71-81
12. Halloran PF: Interferon-γ, prototype of the proinflammatory cytokines - importance in activation, suppression, and maintenance of the immune response. Transplant Proc 25(suppl 1):10-15, 1993
13. Heufelder AE, Bahn RS: Detection and localization of cytokine immunoreactivity in retro-ocular connective tissue in Graves' opthalmology. Eur J Clin Inv 23:10-17, 1993
14. Howie SEM, Aldridge RD, McVittie E, Thornton E, Ramage E, Hunter JAA: A non-radiolabelled m situ hybridization method for the detection of epidermal cytokine mRNA. J Exp Dermatol 1:230-235, 1992
15. Gawkrodger J, Carr MM, McVittie E, Guy K, Hunter JAA: Keratinocyte expression of MHC class II antigens in allergic sensitization and challenge reactions and in irritant contact dermatitis. J Invest Dermatol 88:11-16, 1987
16. Griffiths CEM, Voorhees JJ, NickolofF BJ: Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin: modulation by recombinant gamma interferon and tumor necrosis factor. J Am Acad Dermatol 20:617-629, 1989
17. Kasahara T, Hooks JJ, Dougherty SF, Oppenheim JJ: Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets. J Immunol 130:1784-1789, 1983
18. Kiefer R, Haas CA, Kreutzberg GW: Gamma interferon-like immunoreactive material in rat neurons: evidence against a close relationship to gamma interferon. Neurosci 45:551-559, 1991
19. McKay IA, Leigh IM: Epidermal cytokines and their roles in cutaneous wound healing. Br J Dermatol 124:513-518, 1991
20. Munakata T, Semba U, Shibuya Y, Kuwano K, Akagi M, Arai S: Induction of interteron-γ production by human natural killer cells stimulated by hydrogen peroxide. J Immunol 134:2449-2455, 1985
21. 125I-gamma interferon to cultured human keratinocytes. J Invest Dermatol 89:132-135, 1987
22. Nickoloff BJ, Naidu Y: Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 30:535-546, 1994
23. Nickoloff BJ, Turka LA: Keratinocytes: key immunocytes of the integument. Am J Pathol 143:325-331, 1993
24. Olsson T, Kelic S, Edlund C, Bakhiet M, Höjeberg B, van der Meide PH, Ljungdahl Å, Kristensson K: Neuronal interferon-γ immunoreactive molecule: bioactivities and purification. Eur J Immunol 24:308-314, 1994
25. Rady PL, Cadet P, Bui TK, Tyring SK, Baron S, Stanton GJ. Hughes TK: Production of interferon gamma messenger RNA by cells of non-immune origin. Cytokine 7:793-798, 1995
26. Scheynius A, Fransson J, Johansson C, Hammar H, Baker B, Fry L, Valdimarsson H: Expression of interferon-gamma receptors in normal and psoriatic skin. J Invest Dermatol 98:255-258, 1992
27. Thomson JA, Troutt AB, Kelso A: Contact sensitization to oxazolone: involvement of both interferon-γ and interleukin-4 in oxazolone-specific Ig and T-cell responses. Immunology 78:185-192, 1993