메뉴 건너뛰기




Volumn 34, Issue 5, 1999, Pages 385-390

Molecular detection of minimal residual disease in colorectal and breast cancer

Author keywords

Breast cancer; Colorectal cancer; Micrometastases; RT PCR

Indexed keywords

BREAST CANCER; CANCER STAGING; COLORECTAL CANCER; DIAGNOSTIC VALUE; HUMAN; LYMPH NODE METASTASIS; MEDICAL DECISION MAKING; METASTASIS POTENTIAL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; TREATMENT PLANNING;

EID: 0033019611     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.1999.00716.x     Document Type: Review
Times cited : (20)

References (54)
  • 1
    • 0026763520 scopus 로고
    • The importance of combining xylene clearance and immunohistochemistry in the accurate staging of colorectal carcinoma
    • 1. Haboubi NY, Clark P, Kaftan SM et al. The importance of combining xylene clearance and immunohistochemistry in the accurate staging of colorectal carcinoma. J. R. Soc. Med. 1992; 85; 386-388.
    • (1992) J. R. Soc. Med. , vol.85 , pp. 386-388
    • Haboubi, N.Y.1    Clark, P.2    Kaftan, S.M.3
  • 2
    • 0025297298 scopus 로고
    • Prognostic importance of occult axillary lymph node micrometastases from breast cancer
    • 2. International (Ludwig) breast cancer study group. Prognostic importance of occult axillary lymph node micrometastases from breast cancer. Lancet 1990; 335; 1565-1568.
    • (1990) Lancet , vol.335 , pp. 1565-1568
  • 3
    • 0026059221 scopus 로고
    • Restaging of colorectal cancer based on the identification of lymph node micrometastases through immunoperoxidase staining of CEA and cytokeratins
    • 3. Cutait R, Alves VAF, Lopes LC. Restaging of colorectal cancer based on the identification of lymph node micrometastases through immunoperoxidase staining of CEA and cytokeratins. Dis. Colon Rectum 1991; 34; 917-920.
    • (1991) Dis. Colon Rectum , vol.34 , pp. 917-920
    • Cutait, R.1    Alves, V.A.F.2    Lopes, L.C.3
  • 4
    • 0030743467 scopus 로고    scopus 로고
    • Comparative analysis of bone marrow and venous blood isolates from gastrointestinal cancer patients for the detection of disseminated tumor cells using reverse transcriplase PCR
    • 4. Soeth E, Vogel I, Röder C et al. Comparative analysis of bone marrow and venous blood isolates from gastrointestinal cancer patients for the detection of disseminated tumor cells using reverse transcriplase PCR. Cancer Res. 1997; 57; 3106-3610.
    • (1997) Cancer Res. , vol.57 , pp. 3106-3610
    • Soeth, E.1    Vogel, I.2    Röder, C.3
  • 5
    • 0031953025 scopus 로고    scopus 로고
    • Meta-analysis of studies on bone marrow micrometastases: An independent prognostic impact remains to be substantiated
    • 5. Funke I, Schraut W. Meta-analysis of studies on bone marrow micrometastases: an independent prognostic impact remains to be substantiated. J. Clin. Oncol. 1998; 16; 557-566.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 557-566
    • Funke, I.1    Schraut, W.2
  • 6
    • 0028814029 scopus 로고
    • Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck
    • 6. Brennan JA, Mao L, Hruban RH et al. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N. Engl. J. Med. 1995; 332; 429-435.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 429-435
    • Brennan, J.A.1    Mao, L.2    Hruban, R.H.3
  • 7
    • 0028148570 scopus 로고
    • Lymphatic mapping and sentinel lymphadenectomy for breast cancer
    • 7. Giuliano AE, Kirgan DM, Guenther JM et al. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann. Surg. 1994; 220; 391-398.
    • (1994) Ann. Surg. , vol.220 , pp. 391-398
    • Giuliano, A.E.1    Kirgan, D.M.2    Guenther, J.M.3
  • 8
    • 0026590057 scopus 로고
    • Technical details of intraoperative lymphatic mapping for early stage melanoma
    • 8. Morton DL, Wen DR, Wong JH et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch. Surg. 1993; 127; 392-399.
    • (1993) Arch. Surg. , vol.127 , pp. 392-399
    • Morton, D.L.1    Wen, D.R.2    Wong, J.H.3
  • 9
    • 0032522958 scopus 로고    scopus 로고
    • Utilization of polymerase chain reaction technology in the detection of solid tumors
    • 9. Raj GV, Moreno JG, Gomella LG. Utilization of polymerase chain reaction technology in the detection of solid tumors. Cancer 1998; 82; 1419-1442.
    • (1998) Cancer , vol.82 , pp. 1419-1442
    • Raj, G.V.1    Moreno, J.G.2    Gomella, L.G.3
  • 10
    • 0031929915 scopus 로고    scopus 로고
    • Mutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancer
    • 10. Berns EM, van Staveron IL, Look MP et al. Mutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancer. Br. J. Cancer 1998; 77; 1130-1136.
    • (1998) Br. J. Cancer , vol.77 , pp. 1130-1136
    • Berns, E.M.1    Van Staveron, I.L.2    Look, M.P.3
  • 11
    • 0024387728 scopus 로고
    • Mutations in the p53 gene occur in diverse human tumour types
    • 11. Nigro JM, Baker SJ, Preisinger AC et al. Mutations in the p53 gene occur in diverse human tumour types. Nature 1989; 342; 705-708.
    • (1989) Nature , vol.342 , pp. 705-708
    • Nigro, J.M.1    Baker, S.J.2    Preisinger, A.C.3
  • 12
    • 0028288298 scopus 로고
    • Specific detection of carcinoembryonic antigen expressing tumor cells in bone marrow aspirates by polymerase chain reaction
    • 12. Gerhard M, Juhl H, Kalthoff H et al. Specific detection of carcinoembryonic antigen expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J. Clin. Oncol. 1994; 12; 725-729.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 725-729
    • Gerhard, M.1    Juhl, H.2    Kalthoff, H.3
  • 13
    • 0033524377 scopus 로고    scopus 로고
    • Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells
    • 13. Ruud P, Fodstad O, Hovig E. Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells. Int J. Cancer 1999; 80; 119-125.
    • (1999) Int J. Cancer , vol.80 , pp. 119-125
    • Ruud, P.1    Fodstad, O.2    Hovig, E.3
  • 14
    • 0031024178 scopus 로고    scopus 로고
    • Immunobead RTPCR. A sensitive method for detection of circulating tumor cells
    • 14. Eaton MC, Hardingham JE, Kotasek D, Dobrovic A. Immunobead RTPCR. A sensitive method for detection of circulating tumor cells. Biotechniques 1997; 22; 100-105.
    • (1997) Biotechniques , vol.22 , pp. 100-105
    • Eaton, M.C.1    Hardingham, J.E.2    Kotasek, D.3    Dobrovic, A.4
  • 15
    • 0029079321 scopus 로고
    • pTNM and residual tumor classification: Problems of assessment and prognostic significance
    • 15. Hermanek P. pTNM and residual tumor classification: problems of assessment and prognostic significance. World J. Surg. 1995; 19; 184-190.
    • (1995) World J. Surg. , vol.19 , pp. 184-190
    • Hermanek, P.1
  • 16
    • 0028351657 scopus 로고
    • Chemotherapy for colorectal cancer
    • 16. Moertel CG. Chemotherapy for colorectal cancer. N. Engl. J. Med. 1994; 330; 1136-1142.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 1136-1142
    • Moertel, C.G.1
  • 17
    • 0028835122 scopus 로고
    • Intergroup study of fluorouracil plus levamisol as adjuvant therapy for stage II/Dukes' B2 colon cancer
    • 17. Moertel CG, Fleming TR, Macdonald JS et al. Intergroup study of fluorouracil plus levamisol as adjuvant therapy for stage II/Dukes' B2 colon cancer. J. Clin. Oncol. 1995; 13; 2936-2943.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2936-2943
    • Moertel, C.G.1    Fleming, T.R.2    Macdonald, J.S.3
  • 18
    • 0024605518 scopus 로고
    • Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)
    • 18. Newton CR, Graham A, Heptinstall LE et al. Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res. 1989: 17; 2503-2516.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 2503-2516
    • Newton, C.R.1    Graham, A.2    Heptinstall, L.E.3
  • 19
    • 0029648689 scopus 로고
    • Genetic diagnosis of lymph node metastasis in colorectal cancer
    • 19. Hayashi N, Ito I, Yanagisawa A et al. Genetic diagnosis of lymph node metastasis in colorectal cancer. Lancet 1995; 345; 1257-1259.
    • (1995) Lancet , vol.345 , pp. 1257-1259
    • Hayashi, N.1    Ito, I.2    Yanagisawa, A.3
  • 20
    • 0030804660 scopus 로고    scopus 로고
    • Predictive value of genetic diagnosis for cancer micrometastasis
    • 20. Yamamoto N, Kato Y, Yanagisawa A et al. Predictive value of genetic diagnosis for cancer micrometastasis. Cancer 1997; 80; 1393-1398.
    • (1997) Cancer , vol.80 , pp. 1393-1398
    • Yamamoto, N.1    Kato, Y.2    Yanagisawa, A.3
  • 21
    • 0031904274 scopus 로고    scopus 로고
    • Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients
    • 21. Rostick PJ. Chatterjee S, Chi DD et al. Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients. J. Clin. Oncol. 1998; 16; 2632-2640.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2632-2640
    • Rostick, P.J.1    Chatterjee, S.2    Chi, D.D.3
  • 22
    • 0028815392 scopus 로고
    • Detection of epithelial cancer cells in peripheral lood by reverse transcriptase-polymerase chain reaction
    • 22. Burchill SA, Bradbury MF, Pittman K et al. Detection of epithelial cancer cells in peripheral lood by reverse transcriptase-polymerase chain reaction. Br. J. Cancer 1995; 71; 278-281.
    • (1995) Br. J. Cancer , vol.71 , pp. 278-281
    • Burchill, S.A.1    Bradbury, M.F.2    Pittman, K.3
  • 23
    • 0029964831 scopus 로고    scopus 로고
    • Detection of micrometastases in colorectal cancer patients by K19 and K20 reverse-transcription polymerase chain reaction
    • 23. Gunn J, McCall JL, Yun K, Wright PA. Detection of micrometastases in colorectal cancer patients by K19 and K20 reverse-transcription polymerase chain reaction. Lab. Invest. 1996; 75; 611-616.
    • (1996) Lab. Invest. , vol.75 , pp. 611-616
    • Gunn, J.1    McCall, J.L.2    Yun, K.3    Wright, P.A.4
  • 25
    • 0031963241 scopus 로고    scopus 로고
    • Genetic detection of lymph node micrometastases in patients with colorectal cancer
    • 25. Dorudi S, Kinrade E, Marshall NC et al. Genetic detection of lymph node micrometastases in patients with colorectal cancer. Br. J. Surg. 1998; 85; 98-100.
    • (1998) Br. J. Surg. , vol.85 , pp. 98-100
    • Dorudi, S.1    Kinrade, E.2    Marshall, N.C.3
  • 26
    • 0031750263 scopus 로고    scopus 로고
    • Spread of colorectal cancer micrometastases in regional lymph nodes by reverse transcriptase-polymerase chain reactions for carcinoembryonic antigen and cytokeratin
    • 26. Futamura M, Takagi Y, Koumura H et al. Spread of colorectal cancer micrometastases in regional lymph nodes by reverse transcriptase-polymerase chain reactions for carcinoembryonic antigen and cytokeratin. J. Surg. Oncol. 1998; 68; 34-40.
    • (1998) J. Surg. Oncol. , vol.68 , pp. 34-40
    • Futamura, M.1    Takagi, Y.2    Koumura, H.3
  • 27
    • 0025911082 scopus 로고
    • CEA in tumours of other than colorectal origin
    • 27. Chevinsky AH. CEA in tumours of other than colorectal origin. Semin. Surg. Oncol. 1991; 7; 162-166.
    • (1991) Semin. Surg. Oncol. , vol.7 , pp. 162-166
    • Chevinsky, A.H.1
  • 28
    • 0021902411 scopus 로고
    • CEA related antigens: Molecular biology and clinical significance
    • 28. Shively JE, Beatty JD. CEA related antigens: molecular biology and clinical significance. Crit. Rev. Oncol. Hematol. 1985; 2; 355-399.
    • (1985) Crit. Rev. Oncol. Hematol , vol.2 , pp. 355-399
    • Shively, J.E.1    Beatty, J.D.2
  • 30
    • 0029100684 scopus 로고
    • Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction
    • 30. Mori M, Mimori K, Inoue H et al. Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res. 1995; 55; 3417-3420.
    • (1995) Cancer Res. , vol.55 , pp. 3417-3420
    • Mori, M.1    Mimori, K.2    Inoue, H.3
  • 31
    • 0027029553 scopus 로고
    • Illegitimate transcription: Its use in the study of inherited disease
    • 31. Kaplan JC, Kahn A, Chelly J. Illegitimate transcription: its use in the study of inherited disease. Human Mutation 1992; 1; 357-360.
    • (1992) Human Mutation , vol.1 , pp. 357-360
    • Kaplan, J.C.1    Kahn, A.2    Chelly, J.3
  • 32
    • 0032483679 scopus 로고    scopus 로고
    • Meeting highlights: International consensus panel on the treatment of primary breast cancer
    • 32. Goldhirsch A, Glick JH, Gelber RD, Senn HJ. Meeting highlights: International consensus panel on the treatment of primary breast cancer. J. Natl. Cancer Inst. 1998: 90; 1601-1008.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 1601-11008
    • Goldhirsch, A.1    Glick, J.H.2    Gelber, R.D.3    Senn, H.J.4
  • 33
    • 0030063823 scopus 로고    scopus 로고
    • Detection of breast cancer micrometastases in axillary lymph nodes by means of reverse transcriptasepolymerase chain reaction: Comparison between MUC1 mRNA and keratin 19 mRNA amplification
    • 33. Noguchi S, Aihara T, Motomura K et al. Detection of breast cancer micrometastases in axillary lymph nodes by means of reverse transcriptasepolymerase chain reaction: Comparison between MUC1 mRNA and keratin 19 mRNA amplification. Am. J. Pathol. 1996; 148; 649-656.
    • (1996) Am. J. Pathol. , vol.148 , pp. 649-656
    • Noguchi, S.1    Aihara, T.2    Motomura, K.3
  • 34
    • 0028223380 scopus 로고
    • Sensitive detection of occult breast cancer by the reverse transcriptase polymerase chain reaction
    • 34. Datta YH, Adams PT, Drobyski WR et al. Sensitive detection of occult breast cancer by the reverse transcriptase polymerase chain reaction. J. Clin. Oncol. 1994; 12; 475482.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 475482
    • Datta, Y.H.1    Adams, P.T.2    Drobyski, W.R.3
  • 35
    • 0028234677 scopus 로고
    • Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction
    • 35. Schoenfeld A. Luqmani Y, Smith D et al. Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction. Cancer Res. 1994; 54; 2986-2990.
    • (1994) Cancer Res. , vol.54 , pp. 2986-2990
    • Schoenfeld, A.1    Luqmani, Y.2    Smith, D.3
  • 36
    • 0029811828 scopus 로고    scopus 로고
    • High-sensitivity detection of minimal residual breast carcinoma using the polymerase chain reaction and primers for cytokeratin 19
    • 36. Moscinski LC, Trudeau WL, Fields KK, Elfenbein GJ. High-sensitivity detection of minimal residual breast carcinoma using the polymerase chain reaction and primers for cytokeratin 19. Diagn. Mol. Pathol. 1996; 5; 173-180.
    • (1996) Diagn. Mol. Pathol. , vol.5 , pp. 173-180
    • Moscinski, L.C.1    Trudeau, W.L.2    Fields, K.K.3    Elfenbein, G.J.4
  • 37
    • 7844252268 scopus 로고    scopus 로고
    • Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RTPCR for cytokeratin 19 mRNA
    • 37. Vannucchi AM, Bosi A, Glinz S et al. Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RTPCR for cytokeratin 19 mRNA, Br. J. Haematol. 1998; 103; 610-617.
    • (1998) Br. J. Haematol. , vol.103 , pp. 610-617
    • Vannucchi, A.M.1    Bosi, A.2    Glinz, S.3
  • 38
    • 10244237724 scopus 로고    scopus 로고
    • Detection of cancer cells in peripheral blood stem cells of women with breast cancer by RTPCR and cell culture
    • 38. Kruger WH, Stockschlader M, Hennings S et al. Detection of cancer cells in peripheral blood stem cells of women with breast cancer by RTPCR and cell culture. Bone Marrow Transplant. 1996; 1; S1820.
    • (1996) Bone Marrow Transplant. , vol.1
    • Kruger, W.H.1    Stockschlader, M.2    Hennings, S.3
  • 39
    • 0029811977 scopus 로고    scopus 로고
    • Histologic characteristics of breast cancers with occult lymph node metastases detected by keratin 19 mRNA reverse transcriptase-polymerase chain reaction
    • 39. Noguchi S, Aihara T, Motomura K et al. Histologic characteristics of breast cancers with occult lymph node metastases detected by keratin 19 mRNA reverse transcriptase-polymerase chain reaction. Cancer 1996; 78; 1235-1240.
    • (1996) Cancer , vol.78 , pp. 1235-1240
    • Noguchi, S.1    Aihara, T.2    Motomura, K.3
  • 40
    • 0032532390 scopus 로고    scopus 로고
    • Identification of superior markers for polymerase chain reaction detection of breast cancer metastases in sentinal lymph nodes
    • 40. Min CJ, Tafra L, Verbanac KM. Identification of superior markers for polymerase chain reaction detection of breast cancer metastases in sentinal lymph nodes. Cancer Res. 1998; 58; 4581-4584.
    • (1998) Cancer Res. , vol.58 , pp. 4581-4584
    • Min, C.J.1    Tafra, L.2    Verbanac, K.M.3
  • 41
    • 0030056285 scopus 로고    scopus 로고
    • Mammaglobin, a mammary specific member of the uteroglobin gene family, is overexpressed in human breast cancer
    • 41. Watson MA, Fleming TP. Mammaglobin, a mammary specific member of the uteroglobin gene family, is overexpressed in human breast cancer. Cancer Res. 1996; 56; 860-865.
    • (1996) Cancer Res. , vol.56 , pp. 860-865
    • Watson, M.A.1    Fleming, T.P.2
  • 42
    • 0031972653 scopus 로고    scopus 로고
    • Clinical significance of molecular detection of carcinoma cells in lymph nodes and peripheral blood by reverse transcription-polymerase chain reaction in patients with gastrointestinal or breast cancer
    • 42. Mori M, Mimori K, Ueo H. Clinical significance of molecular detection of carcinoma cells in lymph nodes and peripheral blood by reverse transcription-polymerase chain reaction in patients with gastrointestinal or breast cancer. J. Clin. Oncol. 1998; 16; 128-132.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 128-132
    • Mori, M.1    Mimori, K.2    Ueo, H.3
  • 43
    • 0032437669 scopus 로고    scopus 로고
    • Detection of cancer cells in peripheral blood of breast cancer patients using reverse transcription polymerase chain reaction for epidermal growth factor receptor
    • 43. Leitzel K, Lieu B. Curley E. Detection of cancer cells in peripheral blood of breast cancer patients using reverse transcription polymerase chain reaction for epidermal growth factor receptor. Clin. Cancer Res. 1998; 4; 3037-3043.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 3037-3043
    • Leitzel, K.1    Lieu, B.2    Curley, E.3
  • 44
    • 0027503872 scopus 로고
    • Polymerase chain reaction analysis of parathyroid hormone-related protein gene expression in breast cancer patients and occurrence of bone metastases
    • 44. Bouizar Z, Spyratos F, Deytieux S et al. Polymerase chain reaction analysis of parathyroid hormone-related protein gene expression in breast cancer patients and occurrence of bone metastases. Cancer Res. 1993; 53; 5076-5078.
    • (1993) Cancer Res. , vol.53 , pp. 5076-5078
    • Bouizar, Z.1    Spyratos, F.2    Deytieux, S.3
  • 45
    • 0030768933 scopus 로고    scopus 로고
    • Reverse transcriptase-polymerase chain reaction analysis of parathyroid hormonerelated protein for the detection of tumor cell dissemination in the peripheral blood and bone marrow of patients with breast cancer
    • 45. Wulf GG, Jurgens B, Liersch T et al. Reverse transcriptase-polymerase chain reaction analysis of parathyroid hormonerelated protein for the detection of tumor cell dissemination in the peripheral blood and bone marrow of patients with breast cancer. J. Cancer Res. Clin. Oncol. 1997; 123; 514-521.
    • (1997) J. Cancer Res. Clin. Oncol. , vol.123 , pp. 514-521
    • Wulf, G.G.1    Jurgens, B.2    Liersch, T.3
  • 46
    • 0027464958 scopus 로고
    • Heterogeneity of mucin gene expression in normal and neoplastic tissues
    • 46. Ho SB, Niehans GA, Lyftogt C et al. Heterogeneity of mucin gene expression in normal and neoplastic tissues. Cancer Res. 1993; 53; 641-651.
    • (1993) Cancer Res. , vol.53 , pp. 641-651
    • Ho, S.B.1    Niehans, G.A.2    Lyftogt, C.3
  • 47
    • 0029003247 scopus 로고
    • Prognostic value of erbB2 and myc amplification in breast cancer imprints
    • 47. Lonn U, Lonn S, Nilsson B, Stenkvist B. Prognostic value of erbB2 and myc amplification in breast cancer imprints. Cancer 1995; 75; 2681-2687.
    • (1995) Cancer , vol.75 , pp. 2681-2687
    • Lonn, U.1    Lonn, S.2    Nilsson, B.3    Stenkvist, B.4
  • 48
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER2/neu oncogene
    • 48. Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: correlation of relapse and survival with amplification of the HER2/neu oncogene. Science 1987; 235; 177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 49
    • 0032894125 scopus 로고    scopus 로고
    • Detection of aberrant promotor hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
    • 49. Esteller M, Sanchez-Cespedes M, Rosell R et al. Detection of aberrant promotor hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res. 1999; 59; 67-70.
    • (1999) Cancer Res. , vol.59 , pp. 67-70
    • Esteller, M.1    Sanchez-Cespedes, M.2    Rosell, R.3
  • 50
    • 0032893755 scopus 로고    scopus 로고
    • Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients
    • 50. Wong IHN, Dennis YM, Zhang J et al. Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients. Cancer Res. 1999; 59; 71-73.
    • (1999) Cancer Res. , vol.59 , pp. 71-73
    • Wong, I.H.N.1    Dennis, Y.M.2    Zhang, J.3
  • 51
    • 0025782858 scopus 로고
    • Identification of p53 gene mutations in bladder cancers and urine samples
    • 51. Sidransky D, Von Eschenbach A, Tsai YC. Identification of p53 gene mutations in bladder cancers and urine samples. Science 1991; 252; 706-709.
    • (1991) Science , vol.252 , pp. 706-709
    • Sidransky, D.1    Von Eschenbach, A.2    Tsai, Y.C.3
  • 52
    • 0026537986 scopus 로고
    • Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors
    • 52. Sidransky D, Tokino T, Hamilton SR. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992; 256; 102-105.
    • (1992) Science , vol.256 , pp. 102-105
    • Sidransky, D.1    Tokino, T.2    Hamilton, S.R.3
  • 53
    • 0027299334 scopus 로고
    • Detection of K-ras mutation in sputum by mutant allele specific amplification (MASA)
    • 53. Takeda S, Ichii S, Nakamura Y. Detection of K-ras mutation in sputum by mutant allele specific amplification (MASA). Hum. Mutat. 1993; 2; 112-117.
    • (1993) Hum. Mutat. , vol.2 , pp. 112-117
    • Takeda, S.1    Ichii, S.2    Nakamura, Y.3
  • 54
    • 0032569776 scopus 로고    scopus 로고
    • Detection of carcinoembryonic antigen messenger RNA in lymph nodes from patients with colorectal cancer
    • 54. Liefers GJ. Cleton-Jansen AM, Tollenaar RAEM. Detection of carcinoembryonic antigen messenger RNA in lymph nodes from patients with colorectal cancer. N. Engl. J. Med. 1998; 339; 1642-1644.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 1642-1644
    • Liefers, G.J.1    Cleton-Jansen, A.M.2    Tollenaar, R.A.E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.