Spread of colorectal cancer micrometastases in regional lymph nodes by reverse transcriptase-polymerase chain reactions for carcinoembryonic antigen and cytokeratin 20

Journal of Surgical Oncology

Volumn 68, Issue 1, 1998, Pages 34-40

  Futamura, Manabu ^a   Takagi, Yukihiro ^a   Koumura, Hisashi ^a   Kida, Hisashi ^a   Tanemura, Hiromi ^a   Shimokawa, Kuniyasu ^a   Saji, Shigetoyo ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Carcinoembryonic antigen; Colorectal cancer; Cytokeratin 20; Lymph node micrometastasis; Reverse transcriptase polymerase chain reaction

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CYTOKERATIN; CYTOKERATIN 20; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; PRIORITY JOURNAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOEMBRYONIC ANTIGEN; COLORECTAL NEOPLASMS; FEMALE; HUMANS; INTERMEDIATE FILAMENT PROTEINS; KERATIN-20; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 0031750263     PISSN: 00224790     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9098(199805)68:1<34::AID-JSO8>3.0.CO;2-M     Document Type: Article

References (41)

1. Lopez MJ, Monafo WW: Role of extended resection in the initial treatment of locally advanced colorectal carcinoma. Surgery 1993; 113:365-372.
2. Kune GA, Kune S, Field B, et al.: Survival in patients with large-bowel cancer. A population-based investigation from the Melbourne Colorectal Cancer Study. Dis Colon Rectum 1990;33:938-946.
3. Cohen AM, Tremiterra S, Candela F, et al.: Prognosis of node-positive colon cancer. Cancer 1991;67:1859-1861.
4. Japanese Research Society for Cancer of the Colon and Rectum: "Multi-Institutional Registry of Large Bowel Cancer in Japan," vol. 11, Osaka: 1995.
5. Cutait R, Alves VAF, Lopes LC, et al.: Restaging of colorectal cancer based on the identification of lymph node micrometastases through immunoperoxidase staining of CEA and cytokeratins. Dis Colon Rectum 1991;34:917-920.
6. Davidson BR, Sams VR, Styles J, et al.: Detection of occult nodal metastases in patients with colorectal carcinoma. Cancer 1990;65: 967-970.
7. Pantel K, Schlimok G, Braun S, et al.: Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells. J Natl Cancer Inst 1993;85:1419-1424.
8. Maehara Y, Oshiro T, Endo K, et al.: Clinical significance of occult micrometastasis in lymph nodes from patients with early gastric cancer who died of recurrence. Surgery 1996;119:397-402.
9. Sato K, Miyahara M, Saito T, Kobayashi M: c-myc mRNA over-expression is associated with lymph node metastasis in colorectal cancer. Eur J Cancer 1994;30A:1113-1117.
10. Noguchi S, Hiratsuka M, Furukawa H, et al.: Detection of gastric cancer micrometastases in lymph nodes by amplification of keratin 19 mRNA with reverse transcriptase-polymerase chain reaction. Jpn J Cancer Res 1996;87:650-654.
11. Hayashi N, Ito I, Yanagisawa A, et al.: Genetic diagnosis of lymph-node micrometastasis in colorectal cancer. Lancet 1995; 345:1257-1259.
12. Mori M, Mimori K, Inoue H, et al.: Detection of cancer micro-metastases in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res 1995;55:3417-3420.
13. Moll R, Schiller DL, Franke WW: Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J Cell Biol 1990;111: 567-580.
14. Moll R, Löwe A, Laufer J, Franke WW: Cytokeratin 20 in human carcinomas. Am J Pathol 1992;140:427-447.
15. Moll R, Zimbelmann R, Goldschmidt MD, et al.: The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas. Differentiation 1993;53: 75-93.
16. Japanese Research Society for Cancer of the Colon and Rectum: "General Rules for Clinical and Pathological Studies on Cancer of the Colon, Rectum and Anus," 5th ed. Tokyo: Kanehara-Syuppan, 1994.
17. Chomczynski P, Sacchi N: Single-step method of isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
18. Gerhard M, Juhl H, Kalthoff H, et al.: Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol 1994;12: 725-729.
19. Tokunaga K, Nakamura Y, Sakata K, et al.: Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res 1987;47:5616-5619.
20. Deguchi T, Doi T, Ehara H, et al.: Detection of micrometastatic prostate cancer cells in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res 1993;53:5350-5354.
21. Wang X, Heller R, VanVoorhis N, et al.: Detection of submicroscopic lymph node metastases with polymerase chain reaction in patients with malignant melanoma. Ann Surg 1994;220:768-774.
22. Van der Velde-Zimmermann D, Roijers JFM, Bouwens-Rombouts A, et al.: Molecular test for the detection of tumor cells in blood and sentinel nodes of melanoma patients. Am J Pathol 1996; 149:759-764.
23. Datta YH, Adams PT, Drobyski WR, et al.: Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction. J Clin Oncol 1994;12:475-482.
24. Noguchi S, Aihara T, Motomura K, et al.: Detection of breast cancer micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction. Am J Pathol 1996; 148:649-656.
25. Matsumura M, Niwa Y, Kato N, et al.: Detection of α-fetoprotein mRNA, an indicator of hematogenous spreading hepatocellular carcinoma, in the circulation: A possible predictor of metastatic hepatocellular carcinoma. Hepatology 1994;20:1418-1425.
26. Wagener C, Müller-Wallraf R, Nisson S, et al.: Localization and concentration of carcinoembryonic antigen (CEA) in gastrointestinal tumors: Correlation with CEA levels in plasma. J Natl Cancer Inst 1981;67:539-547.
27. Szymendera J, Nowacki MP, Kozlowicz-Gudzinska I, et al.: Value of serum levels of carcinoembryonic antigen, CEA, and gastrointestinal cancer antigen, GICA or CA 19-9, for preoperative staging and postoperative monitoring of patients with colorectal carcinoma. Dis Colon Rectum 1985;28:895-899.
28. Neumaier M, Gerhard M, Wagener C: Diagnosis of micrometastases by the amplification of tissue-specific genes. Gene 1995; 159:43-47.
29. Moll R, Franke WW, Schiller DL, et al.: The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982;31:11-24.
30. Franke WW, Moll R: Cytoskeletal components of lymphoid organs. Differentiation 1987;36:145-163.
31. Krismann M, Todt B, Schroder J, et al.: Low specificity of cytokeratin 19 reverse transcriptase-polymerase chain reaction analyses for detection of hematogenous lung cancer dissemination, J Clin Oncol 1995;13:2769-2775.
32. Burchill SA, Bradbury MF, Pittman K, et al.: Detection of epithelial cancer cells in peripheral blood by reverse transcriptase-polymerase chain reaction. Br J Cancer 1995;71:278-281.
33. Soeth E, Röder C, Juhl H, et al.: The detection of disseminated tumor cells in bone marrow from colorectal-cancer patients by a cytokeratin-20-specific nested reverse-transcriptase-polymerase-chain reaction is related to the stage of disease. Int J Cancer 1996;69:278-282.
34. Gunn J, McCall JL, Yun K, Wright PA: Detection of micrometastases in colorectal cancer patients by K 19 and K 20 reverse-transcription polymerase chain reaction. Lab Invest 1996;75:611-616.
35. Kuroki M, Arakawa F, Yamamoto H, et al.: Active production and membrane anchoring of carcinoembryonic antigen observed in normal colon mucosa. Cancer Lett 1988;43:151-157.
36. Taat CW, van Lanschot JJB, Gouma DJ, Obertop H: Role of extended lymph node dissection in the treatment of gastrointestinal tumors: A review of the literature. Scand J Gastroenterol 1995;30 Suppl 212:109-116.
37. Hojo K, Vernava III AM, Sugihara K, Katumata K: Preservation of urine voiding and sexual function after rectal cancer surgery. Dis Colon Rectum 1991;34:532-539.
38. Sugihara K, Moriya Y, Akasu T, Fujita S: Pelvic autonomic nerve preservation for patients with rectal carcinoma. Cancer 1996;78: 1871-1880.
39. Monson JRT, Darzi A, Carey PD, Guillou PJ: Prospective evaluation of laparoscopic-assisted colectomy in an unselected group of patients. Lancet 1992;340:831-833.
40. Kwok SPY, Lau WY, Carey PD, et al.: Prospective evaluation of laparoscopic-assisted large-bowel excision for cancer. Ann Surg 1996;223:170-176.
41. Moriya Y, Sugihara K, Akasu T, Fujita S: Patterns of recurrence after nerve-sparing surgery for rectal adenocarcinoma with special reference to loco-regional recurrence. Dis Colon Rectum 1995; 38:1162-1168.