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Volumn 94, Issue 3, 1999, Pages 581-595

Chronic hepatitis C and interferon alpha: Conventional and cumulative meta-analyses of randomized controlled trials

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT ALPHA INTERFERON; VIRUS RNA;

EID: 0033018806     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9270(98)00800-4     Document Type: Article
Times cited : (64)

References (143)
  • 1
    • 0028004308 scopus 로고
    • Pathogenic factors in cirrhosis with and without hepatocellular carcinoma: A multicenter Italian study
    • De Bac C, Stroffolini T, Gaeta GB, et al. Pathogenic factors in cirrhosis with and without hepatocellular carcinoma: A multicenter Italian study. Hepatology. 1994;20:1225-30.
    • (1994) Hepatology , vol.20 , pp. 1225-1230
    • De Bac, C.1    Stroffolini, T.2    Gaeta, G.B.3
  • 2
    • 0024556439 scopus 로고
    • The use of surrogate endpoints in clinical trials (an introduction to series of four papers)
    • Herson J. The use of surrogate endpoints in clinical trials (an introduction to series of four papers). Stat Med 1989;8: 403-4.
    • (1989) Stat Med , vol.8 , pp. 403-404
    • Herson, J.1
  • 3
    • 0025915674 scopus 로고
    • Interferon for non-A, non-B chronic hepatitis. A meta-analysis of randomised clinical trials
    • Tine F, Magrin S, Craxì A, et al. Interferon for non-A, non-B chronic hepatitis. A meta-analysis of randomised clinical trials. J Hepatol 1991;13:192-9.
    • (1991) J Hepatol , vol.13 , pp. 192-199
    • Tine, F.1    Magrin, S.2    Craxì, A.3
  • 4
    • 0029833829 scopus 로고    scopus 로고
    • Meta-analysis of interferon randomized trials in the treatment of viral hepatitis: Effects of dose and duration
    • Poynard T, Leroy V, Cohard M, et al. Meta-analysis of interferon randomized trials in the treatment of viral hepatitis: Effects of dose and duration. Hepatology 1996;24: 778-89.
    • (1996) Hepatology , vol.24 , pp. 778-789
    • Poynard, T.1    Leroy, V.2    Cohard, M.3
  • 5
    • 0030740089 scopus 로고    scopus 로고
    • The effect of interferon on the liver in chronic hepatitis C: A quantitative evaluation of histology by meta-analysis
    • Cammà C, Giunta M, Linea C, et al. The effect of interferon on the liver in chronic hepatitis C: A quantitative evaluation of histology by meta-analysis. J Hepatol 1997;26:1187-99.
    • (1997) J Hepatol , vol.26 , pp. 1187-1199
    • Cammà, C.1    Giunta, M.2    Linea, C.3
  • 6
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C
    • Poynard T, Bedossa P, Opolon P, for the Obsvirc, Metavir, Clinivir and Dosvirc groups. Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997; 349:825-32.
    • (1997) Lancet , vol.349 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 7
    • 0028895409 scopus 로고
    • Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam consultation on meta-analysis
    • Cook DJ, Sackett DL, Spitzer WO. Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam consultation on meta-analysis. J Clin Epidemiol 1995;48:167-71.
    • (1995) J Clin Epidemiol , vol.48 , pp. 167-171
    • Cook, D.J.1    Sackett, D.L.2    Spitzer, W.O.3
  • 8
    • 0028197534 scopus 로고
    • Antiviral effect of lymphoblastoid interferon-alpha on hepatitis C virus in patients with chronic hepatitis type C
    • Chayama K, Arasa Y, Koida I, et al. Antiviral effect of lymphoblastoid interferon-alpha on hepatitis C virus in patients with chronic hepatitis type C. J Gastroenterol Hepatol 1994;9:128-33.
    • (1994) J Gastroenterol Hepatol , vol.9 , pp. 128-133
    • Chayama, K.1    Arasa, Y.2    Koida, I.3
  • 9
    • 0026544302 scopus 로고
    • Detection of hepatitis C virus RNA in serum of patients with chronic hepatitis C treated with interferon-alpha
    • Hagiwara H, Hayashi N, Mita E, et al. Detection of hepatitis C virus RNA in serum of patients with chronic hepatitis C treated with interferon-alpha. Hepatology 1992;15:37-41.
    • (1992) Hepatology , vol.15 , pp. 37-41
    • Hagiwara, H.1    Hayashi, N.2    Mita, E.3
  • 10
    • 0026772470 scopus 로고
    • Long-term follow-up of patients with chronic hepatitis C treated with α-interferon
    • Shindo M, Di Bisceglie AM, Hoofnagle JH. Long-term follow-up of patients with chronic hepatitis C treated with α-interferon. Hepatology 1992;15:1013-6.
    • (1992) Hepatology , vol.15 , pp. 1013-1016
    • Shindo, M.1    Di Bisceglie, A.M.2    Hoofnagle, J.H.3
  • 11
    • 0028924826 scopus 로고
    • Persistent hepatitis C viremia after acute self-limiting post-transfusion hepatitis C
    • Barrera JM, Bruguera M, Ercilla MG, et al. Persistent hepatitis C viremia after acute self-limiting post-transfusion hepatitis C. Hepatology 1995;21:639-44.
    • (1995) Hepatology , vol.21 , pp. 639-644
    • Barrera, J.M.1    Bruguera, M.2    Ercilla, M.G.3
  • 12
    • 0027183297 scopus 로고
    • Long-term carriage of hepatitis C virus with normal aminotransferase after interferon treatment in patients with chronic hepatitis C
    • Kakumu S, Yoshika K, Tanaka K, et al. Long-term carriage of hepatitis C virus with normal aminotransferase after interferon treatment in patients with chronic hepatitis C. J Med Virol 1993;41:65-70.
    • (1993) J Med Virol , vol.41 , pp. 65-70
    • Kakumu, S.1    Yoshika, K.2    Tanaka, K.3
  • 13
    • 0027401835 scopus 로고
    • Detection of hepatitis C virus RNA in patients with chronic hepatitis C virus infections during and after therapy with alpha interferon
    • Kleter GEM, Brouwer JT, Heijtink RA, et al. Detection of hepatitis C virus RNA in patients with chronic hepatitis C virus infections during and after therapy with alpha interferon. Antimicrobiol Agents Chemother 1993;37:595-7.
    • (1993) Antimicrobiol Agents Chemother , vol.37 , pp. 595-597
    • Kleter, G.E.M.1    Brouwer, J.T.2    Heijtink, R.A.3
  • 14
    • 0027276247 scopus 로고
    • Significance of serum hepatitis C virus RNA levels in chronic hepatitis C
    • Lau JY, Davis GL, Kniffen J, et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993 12;341:1501-4.
    • (1993) Lancet , vol.12 , Issue.341 , pp. 1501-1504
    • Lau, J.Y.1    Davis, G.L.2    Kniffen, J.3
  • 15
    • 0027501361 scopus 로고
    • Appropriate interferon-alpha therapy for chronic hepatitis C: An assessment by quantitative changes in serum hepatitis C virus-RNA
    • Watanabe S, Kobayashi Y, Konishi M, et al. Appropriate interferon-alpha therapy for chronic hepatitis C: An assessment by quantitative changes in serum hepatitis C virus-RNA. Intern Med 1993;32:523-9.
    • (1993) Intern Med , vol.32 , pp. 523-529
    • Watanabe, S.1    Kobayashi, Y.2    Konishi, M.3
  • 16
    • 0028284401 scopus 로고
    • Virological and biochemical long-term follow-up of patients with chronic hepatitis C treated with interferon
    • Castillo I, Bartolome J, Navas S, et al. Virological and biochemical long-term follow-up of patients with chronic hepatitis C treated with interferon. Hepatology 1994;19: 342-6.
    • (1994) Hepatology , vol.19 , pp. 342-346
    • Castillo, I.1    Bartolome, J.2    Navas, S.3
  • 17
    • 0028012650 scopus 로고
    • High sustained response rate and clearance of viremia in chronic hepatitis C after treatment with interferon-a2b for 60 weeks
    • Reichard O, Foberg U, Frydén, A, et al. High sustained response rate and clearance of viremia in chronic hepatitis C after treatment with interferon-a2b for 60 weeks. Hepatology 1994;19:280-5.
    • (1994) Hepatology , vol.19 , pp. 280-285
    • Reichard, O.1    Foberg, U.2    Frydén, A.3
  • 18
    • 0028135409 scopus 로고
    • Hepatic and extrahepatic hepatitis C virus replication in relation to response to interferon therapy
    • Saleh MG, Tibbs CJ, Koskinas J, et al. Hepatic and extrahepatic hepatitis C virus replication in relation to response to interferon therapy. Hepatology 1994;20:1399-404.
    • (1994) Hepatology , vol.20 , pp. 1399-1404
    • Saleh, M.G.1    Tibbs, C.J.2    Koskinas, J.3
  • 19
    • 0028204083 scopus 로고
    • Factors predictive of response to interferon-a therapy in hepatitis C virus infection
    • Tsubota A, Chayama K, Ikeda K, et al. Factors predictive of response to interferon-a therapy in hepatitis C virus infection. Hepatology 1994;19:1088-94.
    • (1994) Hepatology , vol.19 , pp. 1088-1094
    • Tsubota, A.1    Chayama, K.2    Ikeda, K.3
  • 21
    • 0028919926 scopus 로고
    • Hepatic Hepatitis C virus RNA as a predictor of long-term response to interferon-therapy
    • Shindo M, Arai K, Yoshihiro S, et al. Hepatic Hepatitis C virus RNA as a predictor of long-term response to interferon-therapy. Ann Intern Med 1995;122:586-91.
    • (1995) Ann Intern Med , vol.122 , pp. 586-591
    • Shindo, M.1    Arai, K.2    Yoshihiro, S.3
  • 22
    • 0028876148 scopus 로고
    • Efficacy of interferon alfa therapy in chronic hepatitis C patients depends primarly on hepatitis C virus RNA level
    • Yamada G, Takatani M, Kishi F, et al. Kolberg JA. Efficacy of interferon alfa therapy in chronic hepatitis C patients depends primarly on hepatitis C virus RNA level. Hepatology 1995;22:1351-4.
    • (1995) Hepatology , vol.22 , pp. 1351-1354
    • Yamada, G.1    Takatani, M.2    Kishi, F.3    Kolberg, J.A.4
  • 23
    • 0027438330 scopus 로고
    • Long-term follow-up of patients with chronic hepatitis C treated with different doses of interferon-a2b
    • Saracco G, Rosina F, Abate ML, et al. Long-term follow-up of patients with chronic hepatitis C treated with different doses of interferon-a2b. Hepatology 1993;18:1300-5.
    • (1993) Hepatology , vol.18 , pp. 1300-1305
    • Saracco, G.1    Rosina, F.2    Abate, M.L.3
  • 24
    • 0028140281 scopus 로고
    • Virological and biochemical responses to interferon-alpha in chronic hepatitis C
    • Picciotto A, Bardellini E, Borzone S, et al. Virological and biochemical responses to interferon-alpha in chronic hepatitis C. Lancet 1994;343:54-5.
    • (1994) Lancet , vol.343 , pp. 54-55
    • Picciotto, A.1    Bardellini, E.2    Borzone, S.3
  • 25
    • 0030317884 scopus 로고    scopus 로고
    • Persistent hepatitis C viremia predicts late relapse after sustained response to interferon-a in chronic hepatitis C
    • Chemello L, Cavalletto L, Casarin C, et al. Persistent hepatitis C viremia predicts late relapse after sustained response to interferon-a in chronic hepatitis C. Ann Intern Med 1996; 124:1058-60.
    • (1996) Ann Intern Med , vol.124 , pp. 1058-1060
    • Chemello, L.1    Cavalletto, L.2    Casarin, C.3
  • 26
    • 0344249795 scopus 로고
    • Can chronic HCV infection terminate in patients with chronic active hepatitis long-term responders to interferon therapy?
    • abstract
    • Morisco F, Tuccillo C, Sessa G, Can chronic HCV infection terminate in patients with chronic active hepatitis long-term responders to interferon therapy? Gastroenterology 1995; 108:A1126 (abstract).
    • (1995) Gastroenterology , vol.108
    • Morisco, F.1    Tuccillo, C.2    Sessa, G.3
  • 27
    • 0345112164 scopus 로고
    • Four years of follow-up (LTFUP) of patients with chronic hepatitis C (CHC) treated with interferon-α-2a
    • abstract
    • Carreño V, Gerken G, Trèpo C, et al., and a Multicenter Study Group. Four years of follow-up (LTFUP) of patients with chronic hepatitis C (CHC) treated with interferon-α-2a. Hepatology 1995;22:173A (abstract).
    • (1995) Hepatology , vol.22
    • Carreño, V.1    Gerken, G.2    Trèpo, C.3
  • 28
    • 0345112163 scopus 로고
    • Analysis of prognosis of patients with type C chronic hepatitis who treated with interferon
    • abstract
    • Karino Y, Toyota J, Higashino K, et al. Analysis of prognosis of patients with type C chronic hepatitis who treated with interferon. Hepatology 1995;22:177A (abstract).
    • (1995) Hepatology , vol.22
    • Karino, Y.1    Toyota, J.2    Higashino, K.3
  • 29
    • 0028925814 scopus 로고
    • Two-year biochemical, virological, and histological follow-up in patients with chronic hepatitis C responding in a sustained fashion to interferon alfa-2b treatment
    • Reichard O, Glaumann H, Frydén A, et al. Two-year biochemical, virological, and histological follow-up in patients with chronic hepatitis C responding in a sustained fashion to interferon alfa-2b treatment. Hepatology 1995;21:918-22.
    • (1995) Hepatology , vol.21 , pp. 918-922
    • Reichard, O.1    Glaumann, H.2    Frydén, A.3
  • 30
    • 0006646644 scopus 로고
    • Long-term biochemical, virological and histological follow-up in patients with chronic hepatitis C treated with interferon
    • abstract
    • Takahashi M, Yamada G, Tsugeno H, et al. Long-term biochemical, virological and histological follow-up in patients with chronic hepatitis C treated with interferon. Hepatology 1995;22:174A (abstract).
    • (1995) Hepatology , vol.22
    • Takahashi, M.1    Yamada, G.2    Tsugeno, H.3
  • 32
    • 0030071469 scopus 로고    scopus 로고
    • Hepatic hepatitis C virus RNA in chronic hepatitis C
    • letter
    • Craxì A, Di Marco V, Almasio P. Hepatic hepatitis C virus RNA in chronic hepatitis C. Ann Intern Med 1996;124:72 (letter).
    • (1996) Ann Intern Med , vol.124 , pp. 72
    • Craxì, A.1    Di Marco, V.2    Almasio, P.3
  • 33
    • 0029893452 scopus 로고    scopus 로고
    • Lack of sustained efficacy of interferon in patients with chronic hepatitis C
    • letter
    • Vento S, Concia E, Ferraro T. Lack of sustained efficacy of interferon in patients with chronic hepatitis C. N Engl J Med 1996;334:1479-80 (letter).
    • (1996) N Engl J Med , vol.334 , pp. 1479-1480
    • Vento, S.1    Concia, E.2    Ferraro, T.3
  • 34
    • 0024368522 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon alfa. A multicenter randomized, controlled trial
    • Davis GL, Balart LA, Schiff ER, et al., and The Hepatitis Interventional Therapy Group. Treatment of chronic hepatitis C with recombinant interferon alfa. A multicenter randomized, controlled trial. N Engl J Med 1989;321:1501-6.
    • (1989) N Engl J Med , vol.321 , pp. 1501-1506
    • Davis, G.L.1    Balart, L.A.2    Schiff, E.R.3
  • 35
    • 0024981607 scopus 로고
    • Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial
    • Di Bisceglie A, Martin P, Kassianides C, et al. Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. N Engl J Med 1989; 321:1506-10.
    • (1989) N Engl J Med , vol.321 , pp. 1506-1510
    • Di Bisceglie, A.1    Martin, P.2    Kassianides, C.3
  • 36
    • 0024571564 scopus 로고
    • A controlled trial of interferon alfa (lymphoblastoid interferon) in chronic non-A non-B hepatitis
    • Jacyna MR, Brooks MG, Loke RHT, et al. A controlled trial of interferon alfa (lymphoblastoid interferon) in chronic non-A non-B hepatitis. Br Med J 1989;298:80-2.
    • (1989) Br Med J , vol.298 , pp. 80-82
    • Jacyna, M.R.1    Brooks, M.G.2    Loke, R.3
  • 37
    • 0025833507 scopus 로고
    • Interferon alpha-2b treatment of chronic posttransfusion non-A non-B/C hepatitis: Long-term outcome and effect of increase interferon doses in non-responders
    • Schvarcz R, Glaumann H, Weiland O, et al. Interferon alpha-2b treatment of chronic posttransfusion non-A non-B/C hepatitis: long-term outcome and effect of increase interferon doses in non-responders. Scand J Infect Dis 1991;23:413-20.
    • (1991) Scand J Infect Dis , vol.23 , pp. 413-420
    • Schvarcz, R.1    Glaumann, H.2    Weiland, O.3
  • 38
    • 17144458177 scopus 로고
    • Interferon alfa-2b for chronic active hepatitis C: Interim results of an Australian trial
    • Farrell G, Lin R, Schoeman M, et al. Interferon alfa-2b for chronic active hepatitis C: Interim results of an Australian trial. J Hepatol 1990;11(suppl 1):S157.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Farrell, G.1    Lin, R.2    Schoeman, M.3
  • 39
    • 0025671752 scopus 로고
    • Prolonged treatment (18 months) of chronic hepatitis C with recombinant α-interferon in comparison with a control group
    • Gomez-Rubio M, Porres JC, Castillo I, et al. Prolonged treatment (18 months) of chronic hepatitis C with recombinant α-interferon in comparison with a control group. J Hepatol 1990;11(suppl 1):S63-7.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Gomez-Rubio, M.1    Porres, J.C.2    Castillo, I.3
  • 40
    • 0025338416 scopus 로고
    • Recombinant human-interferon therapy for chronic non-A, non-B hepatitis: Second report
    • Kakumu S, Arao M, Yoshioka K, et al. Recombinant human-interferon therapy for chronic non-A, non-B hepatitis: second report. Am J Gastroenterol 1990;85:655-9.
    • (1990) Am J Gastroenterol , vol.85 , pp. 655-659
    • Kakumu, S.1    Arao, M.2    Yoshioka, K.3
  • 41
    • 0025668089 scopus 로고
    • Recombinant human interferon alfa-2a in community-acquired non-A, non-B chronic active hepatitis. Preliminary results of a randomized, controlled trial
    • Realdi G, Diodati G, Bonetti P, et al. Recombinant human interferon alfa-2a in community-acquired non-A, non-B chronic active hepatitis. Preliminary results of a randomized, controlled trial. J Hepatol 1990;11(suppl 1):S68-71.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Realdi, G.1    Diodati, G.2    Bonetti, P.3
  • 42
    • 0025671750 scopus 로고
    • A randomized controlled trial of interferon alfa-2b as therapy for chronic non-A, non-B hepatitis
    • Saracco G, Rosina F, Torrani Cerenzia MR, et al. A randomized controlled trial of interferon alfa-2b as therapy for chronic non-A, non-B hepatitis. J Hepatol 1990;11(suppl 1):S43-9.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Saracco, G.1    Rosina, F.2    Torrani Cerenzia, M.R.3
  • 43
    • 0025611130 scopus 로고
    • A phase II study of interferon alfa-2b treatment of anti-HCV positive and negative chronic NANB hepatitis: Interim analysis
    • Varagona G, Kibbler H, Smith M, et al. A phase II study of interferon alfa-2b treatment of anti-HCV positive and negative chronic NANB hepatitis: Interim analysis. J Hepatol 1990;11(suppl 1):S165.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Varagona, G.1    Kibbler, H.2    Smith, M.3
  • 44
    • 0025768539 scopus 로고
    • Comparison of 1 or 3 MU of interferon alfa-2b and placebo in patients with chronic non-A, non-B hepatitis
    • Causse X, Godinot H, Chevallier M, et al. Comparison of 1 or 3 MU of interferon alfa-2b and placebo in patients with chronic non-A, non-B hepatitis. Gastroenterology 1991;101: 497-502.
    • (1991) Gastroenterology , vol.101 , pp. 497-502
    • Causse, X.1    Godinot, H.2    Chevallier, M.3
  • 45
    • 0025947613 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon alfa
    • Cimino L, Nardone G, Citarella C, et al. Treatment of chronic hepatitis C with recombinant interferon alfa. Ital J Gastroenterol. 1991;23:399-402.
    • (1991) Ital J Gastroenterol. , vol.23 , pp. 399-402
    • Cimino, L.1    Nardone, G.2    Citarella, C.3
  • 46
    • 0026179761 scopus 로고
    • Can the response to interferon treatment be predicted in patients with chronic active hepatitis C
    • Lin R, Grierson J, Schoeman MN, et al. Can the response to interferon treatment be predicted in patients with chronic active hepatitis C. Aust NZ J Med 1991;21:387-92.
    • (1991) Aust NZ J Med , vol.21 , pp. 387-392
    • Lin, R.1    Grierson, J.2    Schoeman, M.N.3
  • 47
    • 0025732689 scopus 로고
    • Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: A multicenter randomized controlled trial from France
    • Marcellin P, Boyer N, Giostra E, et al. Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: A multicenter randomized controlled trial from France. Hepatology 1991;13:393-7.
    • (1991) Hepatology , vol.13 , pp. 393-397
    • Marcellin, P.1    Boyer, N.2    Giostra, E.3
  • 48
    • 0025861529 scopus 로고
    • Randomized, double-blind, placebo-controlled trial of eight-week course of recombinant α-interferon for chronic non-A, non-B hepatitis
    • Omata M, Ito Y, Yokosuka O, et al. Randomized, double-blind, placebo-controlled trial of eight-week course of recombinant α-interferon for chronic non-A, non-B hepatitis. Dig Dis Sci 1991;36:1217-22.
    • (1991) Dig Dis Sci , vol.36 , pp. 1217-1222
    • Omata, M.1    Ito, Y.2    Yokosuka, O.3
  • 49
    • 0025963882 scopus 로고
    • High doses of recombinant α-interferon or gamma-interferon for chronic hepatitis C: A randomized, controlled trial
    • Saez-Royuela F, Porres JC, Moreno A, et al. High doses of recombinant α-interferon or gamma-interferon for chronic hepatitis C: A randomized, controlled trial. Hepatology 1991; 13:327-31.
    • (1991) Hepatology , vol.13 , pp. 327-331
    • Saez-Royuela, F.1    Porres, J.C.2    Moreno, A.3
  • 50
    • 0026448177 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon alpha-2b
    • Terranova R, Luca S. Treatment of chronic hepatitis C with recombinant interferon alpha-2b. J Chemother 1992;4:297-302.
    • (1992) J Chemother , vol.4 , pp. 297-302
    • Terranova, R.1    Luca, S.2
  • 51
    • 0026756333 scopus 로고
    • Peripheral blood lymphocyte subset in patients with chronic hepatitis C-effect of interferon treatment
    • Wejstål R, Norkrans G, Lenkei R, et al. Peripheral blood lymphocyte subset in patients with chronic hepatitis C-effect of interferon treatment. Liver 1992;12:161-7.
    • (1992) Liver , vol.12 , pp. 161-167
    • Wejstål, R.1    Norkrans, G.2    Lenkei, R.3
  • 52
    • 17344389979 scopus 로고
    • Treatment with interferon(s) of community-acquired chronic hepatitis and cirrhosis type C
    • Alberti A, Chemello L, Bonetti P, et al. and TVVH Study Group. Treatment with interferon(s) of community-acquired chronic hepatitis and cirrhosis type C. J Hepatol 1993;17: (suppl 3):S123-6.
    • (1993) J Hepatol , vol.17 , Issue.3 SUPPL.
    • Alberti, A.1    Chemello, L.2    Bonetti, P.3
  • 53
    • 0027214879 scopus 로고
    • Benelux multicentre trial of alpha interferon treatment for chronic hepatitis C: Standard v high dose treatment monitored by biochemical and virological markers (interim analysis)
    • Benelux Multicentre Trial Study Group. Benelux multicentre trial of alpha interferon treatment for chronic hepatitis C: Standard v high dose treatment monitored by biochemical and virological markers (interim analysis). Gut 1993; 34(suppl):S119-20.
    • (1993) Gut , vol.34 , Issue.SUPPL.
  • 54
    • 0027257453 scopus 로고
    • The use of recombinant interferon alfa-2b in elderly patients with anti-HCV positive chronic active hepatitis
    • Bresci G, Del Corso L, Romanelli AM, et al. The use of recombinant interferon alfa-2b in elderly patients with anti-HCV positive chronic active hepatitis. J Am Geriatr Soc 1993;41:857-62.
    • (1993) J am Geriatr Soc , vol.41 , pp. 857-862
    • Bresci, G.1    Del Corso, L.2    Romanelli, A.M.3
  • 55
    • 0027322285 scopus 로고
    • Randomised trial of lymphoblastoid α-interferon in chronic hepatitis C. Effects on inflammation, fibrogenesis and viremia
    • Camps J, Castilla A, Ruiz J, et al. Randomised trial of lymphoblastoid α-interferon in chronic hepatitis C. Effects on inflammation, fibrogenesis and viremia. J Hepatol 1993; 17:390-6.
    • (1993) J Hepatol , vol.17 , pp. 390-396
    • Camps, J.1    Castilla, A.2    Ruiz, J.3
  • 56
    • 0027729213 scopus 로고
    • Recombinant human interferon alfa-2a therapy of chronic hepatitis C with or without cirrhosis: Comparison of 3 or 6 MU for 1 year
    • Caporaso N, Suozzo R, Morisco F, et al. Recombinant human interferon alfa-2a therapy of chronic hepatitis C with or without cirrhosis: comparison of 3 or 6 MU for 1 year. Ital J Gastroenterol 1993;25:482-6.
    • (1993) Ital J Gastroenterol , vol.25 , pp. 482-486
    • Caporaso, N.1    Suozzo, R.2    Morisco, F.3
  • 57
    • 17744406063 scopus 로고
    • α-Interferon in the treatment of chronic viral hepatitis: Effects on fibrogenesis serum markers
    • Capra F, Casaril M, Gabrielli GB, et al. α-Interferon in the treatment of chronic viral hepatitis: Effects on fibrogenesis serum markers. J Hepatol 1993;18:112-8.
    • (1993) J Hepatol , vol.18 , pp. 112-118
    • Capra, F.1    Casaril, M.2    Gabrielli, G.B.3
  • 58
    • 0027473444 scopus 로고
    • Lymphoblastoid α-interferon for chronic hepatitis C: A randomized controlled study
    • Castilla A, Camps-Bansell J, Civeira MP, et al. Lymphoblastoid α-interferon for chronic hepatitis C: A randomized controlled study. Am J Gastroenterol 1993;88:233-9.
    • (1993) Am J Gastroenterol , vol.88 , pp. 233-239
    • Castilla, A.1    Camps-Bansell, J.2    Civeira, M.P.3
  • 59
    • 0027273859 scopus 로고
    • Efficacy of different regimens of interferon alfa-2b treatment in chronic hepatitis C
    • De Bac C, Grimaldi F, Clementi C, et al. Efficacy of different regimens of interferon alfa-2b treatment in chronic hepatitis C. Gut 1993;34(suppl):S135.
    • (1993) Gut , vol.34 , Issue.SUPPL.
    • De Bac, C.1    Grimaldi, F.2    Clementi, C.3
  • 60
    • 0027481146 scopus 로고
    • Randomized controlled trial of recombinant alpha-2a-interferon for chronic hepatitis C: Comparison of alanine aminotransferase normalization versus loss of HCV RNA and anti-HCV IgM
    • Douglas DD, Rakela J, Lin HJ, et al. Randomized controlled trial of recombinant alpha-2a-interferon for chronic hepatitis C: Comparison of alanine aminotransferase normalization versus loss of HCV RNA and anti-HCV IgM. Dig Dis Sci 1993;38:601-7.
    • (1993) Dig Dis Sci , vol.38 , pp. 601-607
    • Douglas, D.D.1    Rakela, J.2    Lin, H.J.3
  • 61
    • 0027404908 scopus 로고
    • Quantitative analysis of hepatitis C virus RNA in serum during interferon alfa therapy
    • Hagiwara H, Hayashi N, Mita E, et al. Quantitative analysis of hepatitis C virus RNA in serum during interferon alfa therapy. Gastroenterology 1993;104:877-83.
    • (1993) Gastroenterology , vol.104 , pp. 877-883
    • Hagiwara, H.1    Hayashi, N.2    Mita, E.3
  • 62
    • 0027416870 scopus 로고
    • Treatment of chronic hepatitis C with high-dose interferon α-2b: A multicenter study
    • Iino S, Hino K, Kuroki T, et al. Treatment of chronic hepatitis C with high-dose interferon α-2b: A multicenter study. Dig Dis Sci 1993;38:612-8.
    • (1993) Dig Dis Sci , vol.38 , pp. 612-618
    • Iino, S.1    Hino, K.2    Kuroki, T.3
  • 63
    • 0027534328 scopus 로고
    • A randomized, controlled trial of weekly administration of lymphoblastoid interferon in patients with chronic hepatitis C
    • Kagawa T, Morizane T, Saito H, et al. A randomized, controlled trial of weekly administration of lymphoblastoid interferon in patients with chronic hepatitis C. J Hepatol 1993; 17:91-6.
    • (1993) J Hepatol , vol.17 , pp. 91-96
    • Kagawa, T.1    Morizane, T.2    Saito, H.3
  • 64
    • 0027401835 scopus 로고
    • Detection of hepatitis C virus RNA in patients with chronic hepatitis C virus infections during and after therapy with alpha interferon
    • Kleter GEM, Brouwer JT, Heijtink RA, et al. Detection of hepatitis C virus RNA in patients with chronic hepatitis C virus infections during and after therapy with alpha interferon. Antimicrob Agents Chemother 1993;37:595-7.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 595-597
    • Kleter, G.E.M.1    Brouwer, J.T.2    Heijtink, R.A.3
  • 65
    • 26544469825 scopus 로고
    • Metreau JM, and the French Group for the Study of NANB/C Chronic Hepatitis Treatment. Gut 1993;S112-3.
    • (1993) Gut
    • Metreau, J.M.1
  • 66
    • 0027230770 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon alfa-2b for nine months
    • Pérez R, Pravia R, Linares A, et al. Treatment of chronic hepatitis C with recombinant interferon alfa-2b for nine months. Gut 1993;34(suppl):S136-8.
    • (1993) Gut , vol.34 , Issue.SUPPL.
    • Pérez, R.1    Pravia, R.2    Linares, A.3
  • 67
    • 0027518070 scopus 로고
    • Low-dose interferon in chronic hepatitis non-A/non-B: Effects on quantitative liver function and structure in a randomized, controlled multicenter trial
    • Reichen J, Solioz M, Bühler H, et al. Low-dose interferon in chronic hepatitis non-A/non-B: Effects on quantitative liver function and structure in a randomized, controlled multicenter trial. Clin Invest 1993;71:888-93.
    • (1993) Clin Invest , vol.71 , pp. 888-893
    • Reichen, J.1    Solioz, M.2    Bühler, H.3
  • 68
    • 0027762815 scopus 로고
    • Histologically advanced chronic hepatitis C treated with recombinant alpha-interferon: A randomized placebo-controlled double-blind cross-over study
    • Sieck JO, Ellis ME, Alfurayh O, et al. Histologically advanced chronic hepatitis C treated with recombinant alpha-interferon: A randomized placebo-controlled double-blind cross-over study. J Hepatol 1993;19:418-23.
    • (1993) J Hepatol , vol.19 , pp. 418-423
    • Sieck, J.O.1    Ellis, M.E.2    Alfurayh, O.3
  • 69
    • 0027964422 scopus 로고
    • Treatment of type C chronic active hepatitis with interferon-α-2a: Treatment duration does not influence biochemical remission but does decrease the relapse rate
    • Attili AF, Natali L, Onori L, et al. Treatment of type C chronic active hepatitis with interferon-α-2a: Treatment duration does not influence biochemical remission but does decrease the relapse rate. J Clin Gastroenterol 1994;19: 214-6.
    • (1994) J Clin Gastroenterol , vol.19 , pp. 214-216
    • Attili, A.F.1    Natali, L.2    Onori, L.3
  • 70
    • 0028217213 scopus 로고
    • Long-term follow-up evaluation in HCV chronic hepatitis treated with alpha-2b interferon. A comparison of two protocols
    • Budillon G, Cimino L, Del Vecchio Blanco C, et al. Long-term follow-up evaluation in HCV chronic hepatitis treated with alpha-2b interferon. A comparison of two protocols. Ital J Gastroenterol 1994;26:16-20.
    • (1994) Ital J Gastroenterol , vol.26 , pp. 16-20
    • Budillon, G.1    Cimino, L.2    Del Vecchio Blanco, C.3
  • 71
    • 0028088836 scopus 로고
    • Treatment of chronic hepatitis C with recombinant human interferon-α2a: Results of a randomized controlled clinical trial
    • Diodati G, Bonetti P, Noventa F, et al. Treatment of chronic hepatitis C with recombinant human interferon-α2a: Results of a randomized controlled clinical trial. Hepatology 1994; 19:1-5.
    • (1994) Hepatology , vol.19 , pp. 1-5
    • Diodati, G.1    Bonetti, P.2    Noventa, F.3
  • 72
    • 0028008814 scopus 로고
    • Comparative efficacy of interferon alfa in cirrhotic and noncirrhotic patients with non-A, non-B, C hepatitis
    • Jouët P, Roudot-Thoraval F, Dhumeaux D, et al., and French Group for the Study of Chronic Hepatitis. Comparative efficacy of interferon alfa in cirrhotic and noncirrhotic patients with non-A, non-B, C hepatitis. Gastroenterology 1994;106: 686-90.
    • (1994) Gastroenterology , vol.106 , pp. 686-690
    • Jouët, P.1    Roudot-Thoraval, F.2    Dhumeaux, D.3
  • 73
    • 0028341753 scopus 로고
    • Viral and host factors that contribute to efficacy of interferon-α2a therapy in patients with chronic hepatitis C
    • Matsumoto A, Tanaka E, Suzuki T, et al. Viral and host factors that contribute to efficacy of interferon-α2a therapy in patients with chronic hepatitis C. Dig Dis Sci 1994;39:1273-80.
    • (1994) Dig Dis Sci , vol.39 , pp. 1273-1280
    • Matsumoto, A.1    Tanaka, E.2    Suzuki, T.3
  • 74
    • 0028256163 scopus 로고
    • Treatment of chronic sporadic-type non-A, non-B hepatitis with lymphoblastoid interferon: Gamma GT levels predictive for response
    • Mazzella G, Salzetta A, Casanova S, et al. Treatment of chronic sporadic-type non-A, non-B hepatitis with lymphoblastoid interferon: Gamma GT levels predictive for response. Dig Dis Sci 1994;39:866-70.
    • (1994) Dig Dis Sci , vol.39 , pp. 866-870
    • Mazzella, G.1    Salzetta, A.2    Casanova, S.3
  • 75
    • 0028144718 scopus 로고
    • Continuous versus intermittent therapy for chronic hepatitis C with recombinant interferon alfa-2a
    • Negro F, Baldi M, Mondardini A, et al. Continuous versus intermittent therapy for chronic hepatitis C with recombinant interferon alfa-2a. Gastroenterology 1994;107:479-85.
    • (1994) Gastroenterology , vol.107 , pp. 479-485
    • Negro, F.1    Baldi, M.2    Mondardini, A.3
  • 76
    • 0028209840 scopus 로고
    • A randomized controlled trial of human lymphoblastoid interferon in patients with compensated type C cirrhosis
    • Saito T, Shinzawa H, Kuboki M, et al. A randomized controlled trial of human lymphoblastoid interferon in patients with compensated type C cirrhosis. Am J Gastroenterol 1994; 89:681-5.
    • (1994) Am J Gastroenterol , vol.89 , pp. 681-685
    • Saito, T.1    Shinzawa, H.2    Kuboki, M.3
  • 77
    • 0029079189 scopus 로고
    • Alpha-interferon treatment of chronic hepatitis C: A controlled, multicentre, prospective study
    • Angelini G, Sgarbi D, Colombari R, et al. Alpha-interferon treatment of chronic hepatitis C: A controlled, multicentre, prospective study. Digestion 1995;56:199-203.
    • (1995) Digestion , vol.56 , pp. 199-203
    • Angelini, G.1    Sgarbi, D.2    Colombari, R.3
  • 78
    • 0028792232 scopus 로고
    • Two dose regimens of recombinant interferon-alpha-2b in chronic hepatitis C virus infection
    • Biøro K, Krarup H, Bell H, et al. Two dose regimens of recombinant interferon-alpha-2b in chronic hepatitis C virus infection. Scand J Gastroenterol 1995;30:1119-24.
    • (1995) Scand J Gastroenterol , vol.30 , pp. 1119-1124
    • Biøro, K.1    Krarup, H.2    Bell, H.3
  • 79
    • 0029156655 scopus 로고
    • Randomized trial comparing three different regimens of alpha-2a interferon in chronic hepatitis C
    • Chemello L, Bonetti P, Cavalletto L, et al. Randomized trial comparing three different regimens of alpha-2a interferon in chronic hepatitis C. Hepatology 1995;22:700-6.
    • (1995) Hepatology , vol.22 , pp. 700-706
    • Chemello, L.1    Bonetti, P.2    Cavalletto, L.3
  • 80
    • 0029938425 scopus 로고    scopus 로고
    • Transfusion-associated chronic hepatitis C: Alpha-n1 interferon for 6 vs. 12 months
    • Craxì A, Di Marco V, Lo Iacono O, et al. Transfusion-associated chronic hepatitis C: Alpha-n1 interferon for 6 vs. 12 months. J Hepatol 1996;24:539-46.
    • (1996) J Hepatol , vol.24 , pp. 539-546
    • Craxì, A.1    Di Marco, V.2    Lo Iacono, O.3
  • 81
    • 0029121339 scopus 로고
    • Randomized controlled trial of recombinant interferon α-2b in the treatment of Chinese patients with chronic hepatitis C
    • Hwang SJ, Chan CY, Lu RH, et al. Randomized controlled trial of recombinant interferon α-2b in the treatment of Chinese patients with chronic hepatitis C. J Inter C 1995;15: 611-6.
    • (1995) J Inter c , vol.15 , pp. 611-616
    • Hwang, S.J.1    Chan, C.Y.2    Lu, R.H.3
  • 82
    • 0028937539 scopus 로고
    • Ability of prolonged interferon treatment to suppress relapse after cessation of therapy in patients with chronic hepatitis C: A multicenter randomized controlled trial
    • Kasahara A, Hayashi N, Hiramatsu N, et al. Ability of prolonged interferon treatment to suppress relapse after cessation of therapy in patients with chronic hepatitis C: A multicenter randomized controlled trial. Hepatology 1995;21: 291-7.
    • (1995) Hepatology , vol.21 , pp. 291-297
    • Kasahara, A.1    Hayashi, N.2    Hiramatsu, N.3
  • 83
    • 0028864271 scopus 로고
    • Interferon alfa-2b for chronic hepatitis C: Effects of dose increment and duration of treatment on response rates
    • Lin R, Roach E, Zimmerman M, et al., for the Australia Hepatitis C Study Group. Interferon alfa-2b for chronic hepatitis C: Effects of dose increment and duration of treatment on response rates. J Hepatol 1995;23:487-96.
    • (1995) J Hepatol , vol.23 , pp. 487-496
    • Lin, R.1    Roach, E.2    Zimmerman, M.3
  • 84
    • 0029048072 scopus 로고
    • Lack of benefit of escalating dosage of interferon alfa in patients with chronic hepatitis C
    • Marcellin P, Pouteau M, Martinot-Peignoux M, et al. Lack of benefit of escalating dosage of interferon alfa in patients with chronic hepatitis C. Gastroenterology 1995;109:156-65.
    • (1995) Gastroenterology , vol.109 , pp. 156-165
    • Marcellin, P.1    Pouteau, M.2    Martinot-Peignoux, M.3
  • 85
    • 0028876371 scopus 로고
    • Randomised trial of effect of interferon-a on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis
    • Nishiguchi S, Kuroki T, Nakatani S, et al. Randomised trial of effect of interferon-a on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis. Lancet 1995;346:1051-5.
    • (1995) Lancet , vol.346 , pp. 1051-1055
    • Nishiguchi, S.1    Kuroki, T.2    Nakatani, S.3
  • 86
    • 0029054011 scopus 로고
    • A comparison of three interferon alfa-2b regimens for the longterm treatment of chronic non-A, non-B hepatitis
    • Poynard T, Bedossa P, Chevallier M, et al., and Multicenter Study Group. A comparison of three interferon alfa-2b regimens for the longterm treatment of chronic non-A, non-B hepatitis. N Engl J Med 1995;332:1457-62.
    • (1995) N Engl J Med , vol.332 , pp. 1457-1462
    • Poynard, T.1    Bedossa, P.2    Chevallier, M.3
  • 87
    • 0029445062 scopus 로고
    • Long-term titrated recombinant interferon-α2a in chronic hepatitis C: A randomized controlled trial
    • Rumi MG, Del Ninno E, Parravicini ML, et al. Long-term titrated recombinant interferon-α2a in chronic hepatitis C: a randomized controlled trial. J Viral Hepatitis 1995;2:73-6.
    • (1995) J Viral Hepatitis , vol.2 , pp. 73-76
    • Rumi, M.G.1    Del Ninno, E.2    Parravicini, M.L.3
  • 88
    • 0028827502 scopus 로고
    • Efficacy of longterm interferon treatment in chronic liver disease evaluated by sensitive polymerase chain reaction assay for hepatitis C virus RNA
    • Yokosuka O, Kato N, Hosoda K, et al. Efficacy of longterm interferon treatment in chronic liver disease evaluated by sensitive polymerase chain reaction assay for hepatitis C virus RNA. Gut 1995;37:721-6.
    • (1995) Gut , vol.37 , pp. 721-726
    • Yokosuka, O.1    Kato, N.2    Hosoda, K.3
  • 89
    • 0028931208 scopus 로고
    • Lymphoblastoid interferon therapy in chronic hepatitis C: Biochemical, virological and histological evaluation of two different doses
    • Picciotto A, Callea F, Varagona G, et al. Lymphoblastoid interferon therapy in chronic hepatitis C: Biochemical, virological and histological evaluation of two different doses. Liver 1995;15:20-4.
    • (1995) Liver , vol.15 , pp. 20-24
    • Picciotto, A.1    Callea, F.2    Varagona, G.3
  • 90
    • 0029080627 scopus 로고
    • A controlled study to determine the optimal dose regimen of interferon-α 2b in chronic hepatitis C
    • Hakozaki Y, Shirahama T, Katou M, A controlled study to determine the optimal dose regimen of interferon-α 2b in chronic hepatitis C. Am J Gastroenterol 1995;90:1246-9.
    • (1995) Am J Gastroenterol , vol.90 , pp. 1246-1249
    • Hakozaki, Y.1    Shirahama, T.2    Katou, M.3
  • 91
    • 0029439020 scopus 로고
    • Comparative study of two high doses of lymphoblastoid interferon in the treatment of chronic hepatitis C: Influence on the levels of ALT, viremia and histological activity
    • Enriquez J, Torras X, Miralles F, et al. Comparative study of two high doses of lymphoblastoid interferon in the treatment of chronic hepatitis C: Influence on the levels of ALT, viremia and histological activity. J Viral Hepatitis 1995;2: 181-7.
    • (1995) J Viral Hepatitis , vol.2 , pp. 181-187
    • Enriquez, J.1    Torras, X.2    Miralles, F.3
  • 92
    • 0027163161 scopus 로고
    • A pilot study of ribavirin and interferon beta for the treatment of chronic hepatitis C
    • Kakumu S, Yoshioka K, Wakita T, et al. A pilot study of ribavirin and interferon beta for the treatment of chronic hepatitis C. Gastroenterology 1993;105:507-12.
    • (1993) Gastroenterology , vol.105 , pp. 507-512
    • Kakumu, S.1    Yoshioka, K.2    Wakita, T.3
  • 93
    • 0028122848 scopus 로고
    • A pilot study of combination therapy with ribavirin plus interferon alfa for interferon alfa-resistant chronic hepatitis C
    • Brillanti S, Garson J, Foli M, et al. A pilot study of combination therapy with ribavirin plus interferon alfa for interferon alfa-resistant chronic hepatitis C. Gastroenterology 1994;107:812-7.
    • (1994) Gastroenterology , vol.107 , pp. 812-817
    • Brillanti, S.1    Garson, J.2    Foli, M.3
  • 94
    • 0028960364 scopus 로고
    • Interferon and ursodeoxycholic acid combined therapy in the treatment of chronic viral C hepatitis: Result from a controlled randomized trial in 80 patients
    • Boucher E, Jouanolle H, Andre P, et al. Interferon and ursodeoxycholic acid combined therapy in the treatment of chronic viral C hepatitis: Result from a controlled randomized trial in 80 patients. Hepatology 1995;21:322-7.
    • (1995) Hepatology , vol.21 , pp. 322-327
    • Boucher, E.1    Jouanolle, H.2    Andre, P.3
  • 95
    • 0028814835 scopus 로고
    • Recombinant interferon-a and ursodeoxycholic acid versus interferon-α alone in the treatment of chronic hepatitis C: A randomized clinical trial with long-term follow-up
    • Angelico M, Gandin C, Pescarmona E, et al. Recombinant interferon-a and ursodeoxycholic acid versus interferon-α alone in the treatment of chronic hepatitis C: A randomized clinical trial with long-term follow-up. Am J Gastroenterol 1995;90:263-9.
    • (1995) Am J Gastroenterol , vol.90 , pp. 263-269
    • Angelico, M.1    Gandin, C.2    Pescarmona, E.3
  • 96
    • 0027415343 scopus 로고
    • Short and long-term effects of interferon on serum markers of hepatitis C virus replication
    • Yatsuhashi H, Inoue O, Inokuchi K, et al. Short and long-term effects of interferon on serum markers of hepatitis C virus replication. J Gastroenterol Hepatol 1993;8:1-6.
    • (1993) J Gastroenterol Hepatol , vol.8 , pp. 1-6
    • Yatsuhashi, H.1    Inoue, O.2    Inokuchi, K.3
  • 97
    • 0027733897 scopus 로고
    • Treatment of six patients with chronic active HCV hepatitis, with low dose natural human interferon alpha administered orally
    • Zielinska W, Paszkiewicz J, Korczak A, et al. Treatment of six patients with chronic active HCV hepatitis, with low dose natural human interferon alpha administered orally. Arch Immunol Ther Exp Warsz 1993;41:253-7.
    • (1993) Arch Immunol Ther Exp Warsz , vol.41 , pp. 253-257
    • Zielinska, W.1    Paszkiewicz, J.2    Korczak, A.3
  • 98
    • 0025644290 scopus 로고
    • Treatment of cryptogenic chronic liver diseases with recombinant alpha-2a interferon. Preliminary results of a randomized controlled clinical trial
    • Bonetti P, Diodati G, Scaccabarozzi S, et al. Treatment of cryptogenic chronic liver diseases with recombinant alpha-2a interferon. Preliminary results of a randomized controlled clinical trial. Ann Ital Med Int 1990;5:169-73.
    • (1990) Ann Ital Med int , vol.5 , pp. 169-173
    • Bonetti, P.1    Diodati, G.2    Scaccabarozzi, S.3
  • 99
    • 0025939049 scopus 로고
    • Therapy of chronic non-A, non-B hepatitis with interferon alfa-2B. A controlled clinical study and long-term follow-up
    • Giudici-Cipriani A, Rainisio C, Ponassi I, et al. Therapy of chronic non-A, non-B hepatitis with interferon alfa-2B. A controlled clinical study and long-term follow-up. Minerva Gastroenterol Dietol 1991;37:85-90.
    • (1991) Minerva Gastroenterol Dietol , vol.37 , pp. 85-90
    • Giudici-Cipriani, A.1    Rainisio, C.2    Ponassi, I.3
  • 100
    • 0028058809 scopus 로고
    • Current status of treatment for chronic viral hepatitis using recombinant interferon alpha
    • Hopf U, Kuther S, Konig V, et al. Current status of treatment for chronic viral hepatitis using recombinant interferon alpha. Dtsch Med Wochenschr 1994;119:961-4.
    • (1994) Dtsch Med Wochenschr , vol.119 , pp. 961-964
    • Hopf, U.1    Kuther, S.2    Konig, V.3
  • 101
    • 0025094404 scopus 로고
    • Long-term treatment of cryptogenic hepatitis C using recombinant interferon alpha
    • Hopf U, Moller B, Konig V, et al. Long-term treatment of cryptogenic hepatitis C using recombinant interferon alpha. Z Gastroenterol 1990;28:453-7.
    • (1990) Z Gastroenterol , vol.28 , pp. 453-457
    • Hopf, U.1    Moller, B.2    Konig, V.3
  • 102
    • 0028469899 scopus 로고
    • Interferon therapy of compensated type C cirrhosis
    • Saito T, Shinzawa H, Takahashi T. Interferon therapy of compensated type C cirrhosis. Nippon Rinsho 1994;52: 1875-9.
    • (1994) Nippon Rinsho , vol.52 , pp. 1875-1879
    • Saito, T.1    Shinzawa, H.2    Takahashi, T.3
  • 103
    • 0025637179 scopus 로고
    • Therapy of chronic post-transfusion non-A, non-B hepatitis with interferon alfa-2b: Swedish experience
    • Weiland O, Schvarcz R, Wejstål R, et al. Therapy of chronic post-transfusion non-A, non-B hepatitis with interferon alfa-2b: Swedish experience. J Hepatol 1990;11:S57-62.
    • (1990) J Hepatol , vol.11
    • Weiland, O.1    Schvarcz, R.2    Wejstål, R.3
  • 104
    • 0025688635 scopus 로고
    • Randomized controlled trial of recombinant interferon alfa-2b in chronic NANB hepatitis: Dose schedules and results
    • Liaw YF Sheen IS Randomized controlled trial of recombinant interferon alfa-2b in chronic NANB hepatitis: Dose schedules and results. J Hepatol 1990;11(suppl 1):S160.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Liaw, Y.F.1    Sheen, I.S.2
  • 105
    • 0025730850 scopus 로고
    • Prediction of response to interferon in patients with chronic active hepatitis C, and evidence that this improves hepatic metabolic function
    • Farrell GC, Lin R, Coverdale S. Prediction of response to interferon in patients with chronic active hepatitis C, and evidence that this improves hepatic metabolic function. Gastroenterol Jpn 1991;26(suppl 3):243-6.
    • (1991) Gastroenterol Jpn , vol.26 , Issue.3 SUPPL. , pp. 243-246
    • Farrell, G.C.1    Lin, R.2    Coverdale, S.3
  • 106
    • 0027021770 scopus 로고
    • Interferon therapy of cryptogenic chronic active liver disease and its relationship to anti-HCV
    • Diodati G, Bonetti P, Tagger A, et al. Interferon therapy of cryptogenic chronic active liver disease and its relationship to anti-HCV. Arch Virol 1992;(suppl 4):299-303.
    • (1992) Arch Virol , Issue.4 SUPPL. , pp. 299-303
    • Diodati, G.1    Bonetti, P.2    Tagger, A.3
  • 107
    • 0027190456 scopus 로고
    • High dose interferon treatment in chronic hepatitis C
    • Iino S. High dose interferon treatment in chronic hepatitis C. Gut 1993;34(suppl):S114-8.
    • (1993) Gut , vol.34 , Issue.SUPPL.
    • Iino, S.1
  • 108
    • 0027209586 scopus 로고
    • Alpha-interferon 2b in the treatment of chronic hepatitis C: Interim report of the first multicentre Australian trial
    • Lin R, Liddle C, Farrell GC. Alpha-interferon 2b in the treatment of chronic hepatitis C: Interim report of the first multicentre Australian trial. Gastroenterol Jpn 1993;28: 101-3.
    • (1993) Gastroenterol Jpn , vol.28 , pp. 101-103
    • Lin, R.1    Liddle, C.2    Farrell, G.C.3
  • 109
    • 0027153479 scopus 로고
    • Interferon therapy in chronic hepatitis C. Evaluation of a low dose maintenance schedule in responder patients
    • Picciotto A, Varagona G, Valle F, et al. Interferon therapy in chronic hepatitis C. Evaluation of a low dose maintenance schedule in responder patients. J Hepatol 1993;17:359-63.
    • (1993) J Hepatol , vol.17 , pp. 359-363
    • Picciotto, A.1    Varagona, G.2    Valle, F.3
  • 110
    • 0028029886 scopus 로고
    • Prevention of relapse in patients with chronic non-A, non-B/C hepatitis who respond to alpha-interferon. A controlled multicenter trial of low-dose maintenance therapy
    • Valla D, Babany G, Ouzan D, et al, and Grp Et Multictr interferon dans Hépatites. Prevention of relapse in patients with chronic non-A, non-B/C hepatitis who respond to alpha-interferon. A controlled multicenter trial of low-dose maintenance therapy. J Hepatol 1994;21:774-8.
    • (1994) J Hepatol , vol.21 , pp. 774-778
    • Valla, D.1    Babany, G.2    Ouzan, D.3
  • 111
    • 0027489770 scopus 로고
    • Histological outcome of chronic hepatitis C treated with a 12-month course of lymphoblastoid alfa interferon
    • De AlavaE, Camps J, Pardo-Mindán J, Histological outcome of chronic hepatitis C treated with a 12-month course of lymphoblastoid alfa interferon. Liver 1993;13:73-9.
    • (1993) Liver , vol.13 , pp. 73-79
    • De AlavaE1    Camps, J.2    Pardo-Mindán, J.3
  • 112
    • 0025947742 scopus 로고
    • A randomized controlled trial of recombinant interferon-a in chronic hepatitis C in hemophiliacs
    • Makris M, Preston FE, Triger DR, et al. A randomized controlled trial of recombinant interferon-a in chronic hepatitis C in hemophiliacs. Blood 1991;78:1672-7.
    • (1991) Blood , vol.78 , pp. 1672-1677
    • Makris, M.1    Preston, F.E.2    Triger, D.R.3
  • 113
    • 0028054059 scopus 로고
    • Serum markers of hepatic fibrogenesis in chronic hepatitis type C treated with alfa-2a interferon
    • Gallorini A, Plebani M, Pontisso P, et al. Serum markers of hepatic fibrogenesis in chronic hepatitis type C treated with alfa-2a interferon. Liver 1994;14:257-64.
    • (1994) Liver , vol.14 , pp. 257-264
    • Gallorini, A.1    Plebani, M.2    Pontisso, P.3
  • 114
    • 0028197534 scopus 로고
    • Antiviral effect of lymphoblastoid interferon-alpha on hepatitis C virus in patients with chronic hepatitis type C
    • Chayama K, Arasa Y, Koida I, et al. Antiviral effect of lymphoblastoid interferon-alpha on hepatitis C virus in patients with chronic hepatitis type C. J Gastroenterol Hepatol 1994;9:128-33.
    • (1994) J Gastroenterol Hepatol , vol.9 , pp. 128-133
    • Chayama, K.1    Arasa, Y.2    Koida, I.3
  • 115
    • 0026002152 scopus 로고
    • Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C
    • Shindo M, Di Bisceglie AM, Cheung L, et al. Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C. Ann Intern Med 1991;115:700-4.
    • (1991) Ann Intern Med , vol.115 , pp. 700-704
    • Shindo, M.1    Di Bisceglie, A.M.2    Cheung, L.3
  • 116
    • 0028003887 scopus 로고
    • Assessing health-related quality of life in chronic hepatitis C using the Sickness Impact Profile
    • Davis GL, Balart LA, Schiff ER, et al. Assessing health-related quality of life in chronic hepatitis C using the Sickness Impact Profile. Clin Ther 1994;16:334-43.
    • (1994) Clin Ther , vol.16 , pp. 334-343
    • Davis, G.L.1    Balart, L.A.2    Schiff, E.R.3
  • 117
    • 0029819715 scopus 로고    scopus 로고
    • Comparative efficacy of a high or low dose of interferon alpha 2b in chronic hepatitis C: A randomized controlled trial
    • Tassopoulos NC, Karvountzis G, Touloumi G, et al. Comparative efficacy of a high or low dose of interferon alpha 2b in chronic hepatitis C: A randomized controlled trial. Am J Gastroenterol 1996;91:1734-8.
    • (1996) Am J Gastroenterol , vol.91 , pp. 1734-1738
    • Tassopoulos, N.C.1    Karvountzis, G.2    Touloumi, G.3
  • 118
    • 9244227972 scopus 로고    scopus 로고
    • Low dose alpha interferon therapy can be effective in chronic active hepatitis C. Results of a multicentre, randomised trial
    • Sanchez-Tapias JM, Forns X, Ampurdanes S, et al. Low dose alpha interferon therapy can be effective in chronic active hepatitis C. Results of a multicentre, randomised trial. Gut 1996;38:603-9.
    • (1996) Gut , vol.38 , pp. 603-609
    • Sanchez-Tapias, J.M.1    Forns, X.2    Ampurdanes, S.3
  • 119
    • 0029967851 scopus 로고    scopus 로고
    • Effect of daily administration period of natural alpha-interferon in patients with chronic hepatitis C
    • Toyoda H, Nakano S, Kumada T, et al. Effect of daily administration period of natural alpha-interferon in patients with chronic hepatitis C. Am J Gastroenterol 1996;91:743-7.
    • (1996) Am J Gastroenterol , vol.91 , pp. 743-747
    • Toyoda, H.1    Nakano, S.2    Kumada, T.3
  • 120
    • 0029437224 scopus 로고
    • Clinical efficacy of intramuscular human interferon-beta vs interferon-alpha 2b for the treatment of chronic hepatitis C
    • Perez R, Pravia R, Artimez ML, et al. Clinical efficacy of intramuscular human interferon-beta vs interferon-alpha 2b for the treatment of chronic hepatitis C. J Viral Hepatitis 1995;2:103-6.
    • (1995) J Viral Hepatitis , vol.2 , pp. 103-106
    • Perez, R.1    Pravia, R.2    Artimez, M.L.3
  • 121
    • 8944234351 scopus 로고    scopus 로고
    • Alpha but not beta interferon is useful in chronic active hepatitis due to hepatitis C virus. A prospective, double-blind, randomized study
    • Villa E, Trande P, Grottola A, et al. Alpha but not beta interferon is useful in chronic active hepatitis due to hepatitis C virus. A prospective, double-blind, randomized study. Dig Dis Sci 1996;41:1241-7.
    • (1996) Dig Dis Sci , vol.41 , pp. 1241-1247
    • Villa, E.1    Trande, P.2    Grottola, A.3
  • 122
    • 15444338570 scopus 로고
    • Alpha interferon treatment in chronic hepatitis C
    • Ideo G, Bellobuono A, Mondazzi L, et al. Alpha interferon treatment in chronic hepatitis C. Clin Exp Rheumatol 1995; 13:8167-73.
    • (1995) Clin Exp Rheumatol , vol.13 , pp. 8167-8173
    • Ideo, G.1    Bellobuono, A.2    Mondazzi, L.3
  • 123
    • 0028967863 scopus 로고
    • A comparative randomized controlled study of the efficacy of interferon alfa-2b and interferon alfa-2a in the treatment of chronic hepatitis C
    • Fernandez I, Castellano G, Canga F, et al. A comparative randomized controlled study of the efficacy of interferon alfa-2b and interferon alfa-2a in the treatment of chronic hepatitis C. Gastroenterol Hepatol 1995;18:66-72.
    • (1995) Gastroenterol Hepatol , vol.18 , pp. 66-72
    • Fernandez, I.1    Castellano, G.2    Canga, F.3
  • 124
    • 0029129099 scopus 로고
    • Treatment of chronic hepatitis C with lymphoblastic interferon. Long-term follow-up
    • Passariello N, Sepe J, Peluso A, et al. Treatment of chronic hepatitis C with lymphoblastic interferon. Long-term follow-up. Presse Med 1995;24:1201-6.
    • (1995) Presse Med , vol.24 , pp. 1201-1206
    • Passariello, N.1    Sepe, J.2    Peluso, A.3
  • 125
    • 0029889098 scopus 로고    scopus 로고
    • Improved sustained response following treatment of chronic hepatitis C by gradual reduction in the interferon dose
    • Shiffman ML, Hofmann CM, Luketic VA, et al. Improved sustained response following treatment of chronic hepatitis C by gradual reduction in the interferon dose. Hepatology 1996;24:21-6.
    • (1996) Hepatology , vol.24 , pp. 21-26
    • Shiffman, M.L.1    Hofmann, C.M.2    Luketic, V.A.3
  • 126
    • 0028987904 scopus 로고
    • Pretreatment viral load and response to prolonged interferon-alpha course for chronic hepatitis C
    • Yuki N, Hayashi N, Kasahara A, et al. Pretreatment viral load and response to prolonged interferon-alpha course for chronic hepatitis C. J Hepatol 1995;22:457-63.
    • (1995) J Hepatol , vol.22 , pp. 457-463
    • Yuki, N.1    Hayashi, N.2    Kasahara, A.3
  • 127
    • 0029793505 scopus 로고    scopus 로고
    • New approach to HCV treatment. Recognition of disease process as systemic viral infection rather than as liver disease
    • Friedlander L, van Thiel DH, Faruki H, et al. New approach to HCV treatment. Recognition of disease process as systemic viral infection rather than as liver disease. Dig Dis Sci 1996;41:1678-81.
    • (1996) Dig Dis Sci , vol.41 , pp. 1678-1681
    • Friedlander, L.1    Van Thiel, D.H.2    Faruki, H.3
  • 128
    • 0029449409 scopus 로고
    • Hepatitis C virus RNA and long-term response to recombinant interferon-alpha 2b in patients with chronic hepatitis C
    • Tanno H, Fernandez JL, Rendo P, et al. Hepatitis C virus RNA and long-term response to recombinant interferon-alpha 2b in patients with chronic hepatitis C. J Viral Hepat 1995;2:97-102.
    • (1995) J Viral Hepat , vol.2 , pp. 97-102
    • Tanno, H.1    Fernandez, J.L.2    Rendo, P.3
  • 129
    • 0029912074 scopus 로고    scopus 로고
    • A prospective, randomized trial comparing lymphoblastoid to recombinant interferon alfa 2a as therapy for chronic hepatitis C
    • Rumi M, Del Ninno E, Parravicini ML, et al. A prospective, randomized trial comparing lymphoblastoid to recombinant interferon alfa 2a as therapy for chronic hepatitis C. Hepatology 1996;24:1366-70.
    • (1996) Hepatology , vol.24 , pp. 1366-1370
    • Rumi, M.1    Del Ninno, E.2    Parravicini, M.L.3
  • 130
    • 10344247665 scopus 로고    scopus 로고
    • Response to higher doses of interferon alfa-ab in patients with chronic hepatitis C: Randomized multicenter trial
    • Lindsay KL, Davis GL, Schiff ER, et al., and the Hepatitis Interventional Therapy Group. Response to higher doses of interferon alfa-ab in patients with chronic hepatitis C: Randomized multicenter trial. Hepatology 1996;24:1034-40.
    • (1996) Hepatology , vol.24 , pp. 1034-1040
    • Lindsay, K.L.1    Davis, G.L.2    Schiff, E.R.3
  • 131
    • 18244427901 scopus 로고    scopus 로고
    • A randomized controlled trial of high-dose maintenance interferon therapy in chronic hepatitis C
    • Di Marco V, Lo Iacono O, Cammà C, et al. A randomized controlled trial of high-dose maintenance interferon therapy in chronic hepatitis C. J Med Virol 1997;51:17-24.
    • (1997) J Med Virol , vol.51 , pp. 17-24
    • Di Marco, V.1    Lo Iacono, O.2    Cammà, C.3
  • 134
    • 0025216397 scopus 로고
    • An introduction to a Bayesian method for meta-analysis: The confidence profile method
    • Eddy MD, Hasselblad V, Shachter R. An introduction to a Bayesian method for meta-analysis: The confidence profile method. Med Decis Making 1990;10:15-23.
    • (1990) Med Decis Making , vol.10 , pp. 15-23
    • Eddy, M.D.1    Hasselblad, V.2    Shachter, R.3
  • 136
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959;22:719-48.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 137
    • 0023886431 scopus 로고
    • Reduction in fatal pulmonary embolism and venous thrombosis by peri-operative administration of subcutaneous heparin: Overview of results of randomized trials in general orthopedic and urologic surgery
    • Collin R, Scrimgeour A, Yusuf D, et al. Reduction in fatal pulmonary embolism and venous thrombosis by peri-operative administration of subcutaneous heparin: Overview of results of randomized trials in general orthopedic and urologic surgery. N Engl J Med 1988;5:1162-73.
    • (1988) N Engl J Med , vol.5 , pp. 1162-1173
    • Collin, R.1    Scrimgeour, A.2    Yusuf, D.3
  • 138
    • 0028798488 scopus 로고
    • Cumulative meta-analysis of clinical trials builds evidence for exemplary medical care
    • Lau J, Schmid CH, Chalmers TC. Cumulative meta-analysis of clinical trials builds evidence for exemplary medical care. J Clin Epidemiol 1995;48:45-57.
    • (1995) J Clin Epidemiol , vol.48 , pp. 45-57
    • Lau, J.1    Schmid, C.H.2    Chalmers, T.C.3
  • 139
    • 0026652019 scopus 로고
    • Cumulative meta-analysis of therapeutic trials for myocardial infarction
    • Lau J, Antman EM, Jimenez-Silva J, et al. Cumulative meta-analysis of therapeutic trials for myocardial infarction. N Engl J Med 1992;327:248-54.
    • (1992) N Engl J Med , vol.327 , pp. 248-254
    • Lau, J.1    Antman, E.M.2    Jimenez-Silva, J.3
  • 141
    • 0028331837 scopus 로고
    • Interferon-α for chronic hepatitis C: An analysis of pretreatment clinical predictors of response
    • Pagliaro L, Craxì A, Cammà C, et al. Interferon-α for chronic hepatitis C: An analysis of pretreatment clinical predictors of response. Hepatology 1994;19:820-8.
    • (1994) Hepatology , vol.19 , pp. 820-828
    • Pagliaro, L.1    Craxì, A.2    Cammà, C.3
  • 142
    • 0030458737 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C with α-interferon: An analysis of the literature
    • Niederau C, Heintges T, Häussinger D. Treatment of chronic hepatitis C with α-interferon: An analysis of the literature. Hepato-Gastroenterology 1996;43:1544-56.
    • (1996) Hepato-Gastroenterology , vol.43 , pp. 1544-1556
    • Niederau, C.1    Heintges, T.2    Häussinger, D.3
  • 143
    • 0027402590 scopus 로고
    • Fatal hepatic decompensation associated with interferon alfa
    • Janssen HLA, Brouwer JT, Nevens F, et al. Fatal hepatic decompensation associated with interferon alfa. Br Med J 1993;306:107-8.
    • (1993) Br Med J , vol.306 , pp. 107-108
    • Janssen, H.L.A.1    Brouwer, J.T.2    Nevens, F.3


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