메뉴 건너뛰기




Volumn 38, Issue 4, 1996, Pages 603-609

Low dose α interferon therapy can be effective in chronic active hepatitis C. Results of a multicentre, randomised trial

Author keywords

Hepatitis C therapy; Hepatitis C virus; Interferon

Indexed keywords

ALPHA INTERFERON;

EID: 9244227972     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.38.4.603     Document Type: Article
Times cited : (13)

References (50)
  • 2
    • 0026571061 scopus 로고
    • Prevalence of antibodies to hepatitis C virus among patients with cryptogenic chronic hepatitis and cirrhosis
    • Jeffers LJ, Hasan F, de Medina M, Reddy R, Parker T, Silva M, et al. Prevalence of antibodies to hepatitis C virus among patients with cryptogenic chronic hepatitis and cirrhosis. Hepatology 1992; 15: 187-90.
    • (1992) Hepatology , vol.15 , pp. 187-190
    • Jeffers, L.J.1    Hasan, F.2    De Medina, M.3    Reddy, R.4    Parker, T.5    Silva, M.6
  • 3
    • 0026528427 scopus 로고
    • Non-A, non-B chronic hepatitis is chronic hepatitis C: A sensitive assay for detection of hepatitis C virus RNA in the liver
    • Hosoda K, Omata M, Yokosuka O, Kato N, Ohto M. Non-A, non-B chronic hepatitis is chronic hepatitis C: a sensitive assay for detection of hepatitis C virus RNA in the liver. Hepatology 1992; 15: 777-81.
    • (1992) Hepatology , vol.15 , pp. 777-781
    • Hosoda, K.1    Omata, M.2    Yokosuka, O.3    Kato, N.4    Ohto, M.5
  • 4
    • 0025159304 scopus 로고
    • Long-term follow up of posttransfusion and sporadic chronic hepatitis non-A, non-B and frequency of circulating antibodies to hepatitis C virus (HCV)
    • Hopf U, Möller B, Küter D, Stemerowicz R, Lobeck H, Lüdtke-Handjery, et al. Long-term follow up of posttransfusion and sporadic chronic hepatitis non-A, non-B and frequency of circulating antibodies to hepatitis C virus (HCV). J Hepatol 1990; 10: 69-76.
    • (1990) J Hepatol , vol.10 , pp. 69-76
    • Hopf, U.1    Möller, B.2    Küter, D.3    Stemerowicz, R.4    Lobeck, H.5    Lüdtke-Handjery6
  • 7
    • 0021216860 scopus 로고
    • Hepatocellular carcinoma after non-A, non-B posttransfusion hepatitis
    • Kiyosawa K, Akahane Y, Nagata A, Furata S. Hepatocellular carcinoma after non-A, non-B posttransfusion hepatitis. Am J Gastroenterol 1984; 79: 777-81.
    • (1984) Am J Gastroenterol , vol.79 , pp. 777-781
    • Kiyosawa, K.1    Akahane, Y.2    Nagata, A.3    Furata, S.4
  • 9
    • 0025990456 scopus 로고
    • Effect of interferon administration on serum hepatitis C virus RNA in patients with chronic hepatitis C
    • Chayama K, Saitoh S, Arase Y, Ikeda K, Matsumoto T, Sakai Y, et al. Effect of interferon administration on serum hepatitis C virus RNA in patients with chronic hepatitis C. Hepatology 1991; 13: 1040-3.
    • (1991) Hepatology , vol.13 , pp. 1040-1043
    • Chayama, K.1    Saitoh, S.2    Arase, Y.3    Ikeda, K.4    Matsumoto, T.5    Sakai, Y.6
  • 10
    • 0027404908 scopus 로고
    • Quantitative analysis of hepatitis C virus RNA in serum during interferon alpha therapy
    • Hagiwara H, Hayashi N, Mita E, Takehara T, Kasahara A, Fusamoto H, et al. Quantitative analysis of hepatitis C virus RNA in serum during interferon alpha therapy. Gastroenterology 1993; 104: 877-83.
    • (1993) Gastroenterology , vol.104 , pp. 877-883
    • Hagiwara, H.1    Hayashi, N.2    Mita, E.3    Takehara, T.4    Kasahara, A.5    Fusamoto, H.6
  • 11
    • 17644441983 scopus 로고
    • Histologic changes in liver biopsy specimens produced by recombinant interteron alpha-2b therapy for chronic non-A, non-B viral hepatitis. A randomized controlled trial
    • David E, Pucci A, Palladin D, Saracco G, Garello E, Pintus C, et al. Histologic changes in liver biopsy specimens produced by recombinant interteron alpha-2b therapy for chronic non-A, non-B viral hepatitis. A randomized controlled trial. Am J Clin Pathol 1992; 98: 397-401.
    • (1992) Am J Clin Pathol , vol.98 , pp. 397-401
    • David, E.1    Pucci, A.2    Palladin, D.3    Saracco, G.4    Garello, E.5    Pintus, C.6
  • 12
    • 0348032323 scopus 로고
    • Long-term histological improvement and persistent HCV replication in patients with chronic hepatitis C having responded to recombinant alpha interferon
    • Nishioka K, Suzuki H, Mishiro S, Oda T, eds. Tokyo: Springer-Verlag
    • Marcellin P, Boyer N, Martinot-Peignoux M, Areias J, Giostra E, Degott C, et al. Long-term histological improvement and persistent HCV replication in patients with chronic hepatitis C having responded to recombinant alpha interferon. In: Nishioka K, Suzuki H, Mishiro S, Oda T, eds. Viral hepatitis and liver disease. Tokyo: Springer-Verlag, 1994: 635-7.
    • (1994) Viral Hepatitis and Liver Disease , pp. 635-637
    • Marcellin, P.1    Boyer, N.2    Martinot-Peignoux, M.3    Areias, J.4    Giostra, E.5    Degott, C.6
  • 13
    • 0028597097 scopus 로고
    • Eradication of hepatitis C virus RNA after alpha-interferon therapy
    • Romeo R, Pol S, Berthelot P, Brechot C. Eradication of hepatitis C virus RNA after alpha-interferon therapy. Ann Intern Med 1994; 121: 276-7.
    • (1994) Ann Intern Med , vol.121 , pp. 276-277
    • Romeo, R.1    Pol, S.2    Berthelot, P.3    Brechot, C.4
  • 16
    • 0024368522 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon alpha. A multicentre randomized controlled trial
    • Davis GL, Ballart LA, Schiff ER, Lindsay K, Bodenheimer HC, Perrillo RP, et al. Treatment of chronic hepatitis C with recombinant interferon alpha. A multicentre randomized controlled trial. N Engl J Med 1989; 321: 1501-6.
    • (1989) N Engl J Med , vol.321 , pp. 1501-1506
    • Davis, G.L.1    Ballart, L.A.2    Schiff, E.R.3    Lindsay, K.4    Bodenheimer, H.C.5    Perrillo, R.P.6
  • 17
    • 0025768539 scopus 로고
    • Comparison of 1 or 3 MU of interferon alpha-2b and placebo in patients with chronic non-A, non-B hepatitis
    • Causse X, Godinot H, Ouzan D, Chevalier M, Chossegros P, Zoulim F, et al. Comparison of 1 or 3 MU of interferon alpha-2b and placebo in patients with chronic non-A, non-B hepatitis. Gastroenterology 1991; 101: 497-502.
    • (1991) Gastroenterology , vol.101 , pp. 497-502
    • Causse, X.1    Godinot, H.2    Ouzan, D.3    Chevalier, M.4    Chossegros, P.5    Zoulim, F.6
  • 18
    • 0025732689 scopus 로고
    • Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: A multicentre randomized controlled trial from France
    • Marcellin P, Boyer N, Giostra E, Degott C, Couroucé AM, Degos F, et al. Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: a multicentre randomized controlled trial from France. Hepatology 1991; 13: 393-7.
    • (1991) Hepatology , vol.13 , pp. 393-397
    • Marcellin, P.1    Boyer, N.2    Giostra, E.3    Degott, C.4    Couroucé, A.M.5    Degos, F.6
  • 19
    • 0027438330 scopus 로고
    • Long-term follow-up of patients with chronic hepatitis C treated with different doses of interferon α-2b
    • Saracco G, Rosina F, Abate ML, Chiandussi L, Gallo V, Cerutti E, et al. Long-term follow-up of patients with chronic hepatitis C treated with different doses of interferon α-2b. Hepatology 1993; 18: 1300-5.
    • (1993) Hepatology , vol.18 , pp. 1300-1305
    • Saracco, G.1    Rosina, F.2    Abate, M.L.3    Chiandussi, L.4    Gallo, V.5    Cerutti, E.6
  • 20
    • 0027518070 scopus 로고
    • Low-dose interferon in chronic non-A, non-B hepatitis: Effects on quantitative liver function and structure in a randomized, controlled, multicentre trial
    • Reichen J, Solioz M, Buhler H, Gonvers JJ, Knoblauch M, Lavanchy D, et al. Low-dose interferon in chronic non-A, non-B hepatitis: effects on quantitative liver function and structure in a randomized, controlled, multicentre trial. Clin Investig 1993; 71: 888-93.
    • (1993) Clin Investig , vol.71 , pp. 888-893
    • Reichen, J.1    Solioz, M.2    Buhler, H.3    Gonvers, J.J.4    Knoblauch, M.5    Lavanchy, D.6
  • 22
    • 0027534328 scopus 로고
    • A randomized, controlled trial of lymphoblastoid interferon in patients with chronic hepatitis C
    • Kagawa T, Morizane T, Saito H, Miyaguchi S, Tsunematsu S, Tada S, et al. A randomized, controlled trial of lymphoblastoid interferon in patients with chronic hepatitis C. J Hepatol 1993; 17: 91-6.
    • (1993) J Hepatol , vol.17 , pp. 91-96
    • Kagawa, T.1    Morizane, T.2    Saito, H.3    Miyaguchi, S.4    Tsunematsu, S.5    Tada, S.6
  • 23
    • 0027193025 scopus 로고
    • Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis virus (HCV): Use of type-specific peptides to serologically differentiate infections with HCV type 1, 2 and 3
    • Simmonds P, Rose KA, Graham S, Chan SW, Lin CK, McOmish F, et al. Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis virus (HCV): use of type-specific peptides to serologically differentiate infections with HCV type 1, 2 and 3. J Clin Microbiol 1993; 31: 1493-503.
    • (1993) J Clin Microbiol , vol.31 , pp. 1493-1503
    • Simmonds, P.1    Rose, K.A.2    Graham, S.3    Chan, S.W.4    Lin, C.K.5    McOmish, F.6
  • 24
    • 0025663828 scopus 로고
    • Hepatitis C quantification and sequencing in blood products, haemophiliacs, and drug users
    • Simmonds P, Zhang LQ, Watson HG, Rebus L, Ferguson ED, Balfe P, et al. Hepatitis C quantification and sequencing in blood products, haemophiliacs, and drug users. Lancet 1990; 336: 1469-72.
    • (1990) Lancet , vol.336 , pp. 1469-1472
    • Simmonds, P.1    Zhang, L.Q.2    Watson, H.G.3    Rebus, L.4    Ferguson, E.D.5    Balfe, P.6
  • 25
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Ann Biochem 1987; 162: 156-9.
    • (1987) Ann Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 26
    • 0025146291 scopus 로고
    • Enhanced detection bv PCR of hepatitis C virus RNA
    • Garson JA, Ring C, Tuke P, Tedder RS. Enhanced detection bv PCR of hepatitis C virus RNA [Letter]. Lancet 1990; 336: 878-9.
    • (1990) Lancet , vol.336 , pp. 878-879
    • Garson, J.A.1    Ring, C.2    Tuke, P.3    Tedder, R.S.4
  • 27
    • 0022868893 scopus 로고
    • Treatment of chronic non-A, non-B hepatitis with recombinant human alpha-interferon. A preliminary report
    • Hoofnagle JH, Mullen KD, Jones DB, Rustgi V, Di Bisceglie A, Peters M, et al. Treatment of chronic non-A, non-B hepatitis with recombinant human alpha-interferon. A preliminary report. N Engl J Med 1986; 315: 1575-8.
    • (1986) N Engl J Med , vol.315 , pp. 1575-1578
    • Hoofnagle, J.H.1    Mullen, K.D.2    Jones, D.B.3    Rustgi, V.4    Di Bisceglie, A.5    Peters, M.6
  • 28
    • 0025915674 scopus 로고
    • Interferon for non-A, non-B chronic hepatitis: A meta-analysis of randomized clinical trials
    • Tińe F, Magrin S, Craxí A, Pagliaro L. Interferon for non-A, non-B chronic hepatitis: a meta-analysis of randomized clinical trials. J Hepatol 1991; 13: 192-9.
    • (1991) J Hepatol , vol.13 , pp. 192-199
    • Tińe, F.1    Magrin, S.2    Craxí, A.3    Pagliaro, L.4
  • 29
    • 9244243550 scopus 로고
    • Treatment of chronic hepatitis C with interferon-α
    • Nishioka K, Suzuki H, Mishiro S, Oda T, eds. Tokyo: Springer-Verlag
    • Iino S, Yasuda K, Sainokami S, Hino K. Treatment of chronic hepatitis C with interferon-α. In: Nishioka K, Suzuki H, Mishiro S, Oda T, eds. Viral hepatitis and liver disease. Tokyo: Springer-Verlag, 1994: 607-9.
    • (1994) Viral Hepatitis and Liver Disease , pp. 607-609
    • Iino, S.1    Yasuda, K.2    Sainokami, S.3    Hino, K.4
  • 30
    • 0028066941 scopus 로고
    • Prediction of response to interferon treatment in chronic hepatitis C
    • Davis GL. Prediction of response to interferon treatment in chronic hepatitis C. J Hepatol 1994; 21: 1-3.
    • (1994) J Hepatol , vol.21 , pp. 1-3
    • Davis, G.L.1
  • 31
    • 0028008814 scopus 로고
    • Comparative efficacy of interferon alfa in cirrhotic and non-cirrhotic patients with non-A, non-B, C hepatitis
    • Jouët P, Roudot-Thoraval F, Dhumeaux D, Métreau JM, and Le Groupe Français pour l'Etude du Traitement des Hépatites Chroniques NANB-C. Comparative efficacy of interferon alfa in cirrhotic and non-cirrhotic patients with non-A, non-B, C hepatitis. Gastroenterology 1994; 106: 686-90.
    • (1994) Gastroenterology , vol.106 , pp. 686-690
    • Jouët, P.1    Roudot-Thoraval, F.2    Dhumeaux, D.3    Métreau, J.M.4
  • 32
    • 0028331837 scopus 로고
    • Interferon-α for chronic hepatitis C: An analysis of pretreatment clinical predictors of response
    • Pagliaro L, Craxí A, Cammaá C, Tiné F, Di Marco V, Lo Iacomo O, et al. Interferon-α for chronic hepatitis C: an analysis of pretreatment clinical predictors of response. Hepatology 1994; 19: 820-8.
    • (1994) Hepatology , vol.19 , pp. 820-828
    • Pagliaro, L.1    Craxí, A.2    Cammaá, C.3    Tiné, F.4    Di Marco, V.5    Lo Iacomo, O.6
  • 33
    • 0027230770 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon alfa-2b for nine months
    • Pérez R, Pravia R, Linares A, González M, Rodríguez M, Lombraña JLS, et al. Treatment of chronic hepatitis C with recombinant interferon alfa-2b for nine months. Gut 1992; 34 (suppl): S136-8.
    • (1992) Gut , vol.34 , Issue.SUPPL.
    • Pérez, R.1    Pravia, R.2    Linares, A.3    González, M.4    Rodríguez, M.5    Lombraña, J.L.S.6
  • 34
    • 0027934395 scopus 로고
    • Factors predictive of the response to interferon in patients with chronic hepatitis C
    • Serfati L, Giral P, Loria A, Andreani T, Legendre C, Poupon R. Factors predictive of the response to interferon in patients with chronic hepatitis C. J Hepatol 1994; 21: 12-7.
    • (1994) J Hepatol , vol.21 , pp. 12-17
    • Serfati, L.1    Giral, P.2    Loria, A.3    Andreani, T.4    Legendre, C.5    Poupon, R.6
  • 35
    • 0025637179 scopus 로고
    • Therapy of chronic post-transfusion non-A, non-B hepatitis with interferon alfa-2b: Swedish experience
    • Weiland O, Schvarcz R, Wejstal R, Norkrans G, Fryden A. Therapy of chronic post-transfusion non-A, non-B hepatitis with interferon alfa-2b: Swedish experience. J Hepatol 1990; 11 (suppl 1): S57-62.
    • (1990) J Hepatol , vol.11 , Issue.1 SUPPL.
    • Weiland, O.1    Schvarcz, R.2    Wejstal, R.3    Norkrans, G.4    Fryden, A.5
  • 36
    • 0027008717 scopus 로고
    • Factors predicting early response to treatment with recombinant interferon alpha-2a in chronic non-A, non-B hepatitis. Preliminary report of a long term trial
    • Battezzati PM, Podda M, Bruno S, Zuin M, Crosignani A, Camisasca M, et al. Factors predicting early response to treatment with recombinant interferon alpha-2a in chronic non-A, non-B hepatitis. Preliminary report of a long term trial. Ital J Gastroenterol 1992; 24: 481-4.
    • (1992) Ital J Gastroenterol , vol.24 , pp. 481-484
    • Battezzati, P.M.1    Podda, M.2    Bruno, S.3    Zuin, M.4    Crosignani, A.5    Camisasca, M.6
  • 37
    • 0026734297 scopus 로고
    • Detection of hepatitis C virus by polymerase chain reaction and response to interferon alpha therapy: Relationship to genotypes of hepatitis C virus
    • Yoshioka K, Kakumu S, Wakita T, Ishikawa T, Itoh I, Takayanagi M, et al. Detection of hepatitis C virus by polymerase chain reaction and response to interferon alpha therapy: relationship to genotypes of hepatitis C virus. Hepatology 1992; 16: 293-9.
    • (1992) Hepatology , vol.16 , pp. 293-299
    • Yoshioka, K.1    Kakumu, S.2    Wakita, T.3    Ishikawa, T.4    Itoh, I.5    Takayanagi, M.6
  • 38
    • 0028204083 scopus 로고
    • Factors predictive of response to interferon-α therapy in hepatitis C virus infection
    • Tsubota A, Chayama K, Ikeda K, Yasuji A, Koida I, Saitoh S, et al. Factors predictive of response to interferon-α therapy in hepatitis C virus infection. Hepatology 1994; 19: 1088-94.
    • (1994) Hepatology , vol.19 , pp. 1088-1094
    • Tsubota, A.1    Chayama, K.2    Ikeda, K.3    Yasuji, A.4    Koida, I.5    Saitoh, S.6
  • 39
    • 0028239921 scopus 로고
    • Predicting interferon therapy efficacy from hepatitis C virus genotype and RNA titer
    • Mita E, Hayashi N, Hagiwara H, Ueda K, Kanazawa Y, Kasahara A, et al. Predicting interferon therapy efficacy from hepatitis C virus genotype and RNA titer. Dig Dis Sci 1994; 39: 977-82.
    • (1994) Dig Dis Sci , vol.39 , pp. 977-982
    • Mita, E.1    Hayashi, N.2    Hagiwara, H.3    Ueda, K.4    Kanazawa, Y.5    Kasahara, A.6
  • 40
    • 0011350990 scopus 로고
    • The long-term response (LTR) to interferon-alfa (IFN-2A) in chronic hepatitis C is influenced by dose and duration of treatment and the HCV serotype
    • Chemello L, Pontiso P, Rose KA, Simmonds P, Bonetti P, Cavalletto L, et al. The long-term response (LTR) to interferon-alfa (IFN-2A) in chronic hepatitis C is influenced by dose and duration of treatment and the HCV serotype [Abstract]. J Hepatol 1993; 18 (suppl 1): S10.
    • (1993) J Hepatol , vol.18 , Issue.1 SUPPL.
    • Chemello, L.1    Pontiso, P.2    Rose, K.A.3    Simmonds, P.4    Bonetti, P.5    Cavalletto, L.6
  • 41
    • 2542529118 scopus 로고
    • Efficacy of different regimens of α-interferon in chronic hepatitis C and relationship between response and HCV genotype
    • Bellobuono A, Mondazzi L, Tempini S, Bellati G, Cassará L, Lombino M, et al. Efficacy of different regimens of α-interferon in chronic hepatitis C and relationship between response and HCV genotype [Abstract]. J Hepatol 1994; 21 (suppl 1): S35.
    • (1994) J Hepatol , vol.21 , Issue.1 SUPPL.
    • Bellobuono, A.1    Mondazzi, L.2    Tempini, S.3    Bellati, G.4    Cassará, L.5    Lombino, M.6
  • 42
    • 0028012650 scopus 로고
    • High sustained response rate and clearance of viremia after treatment with interferon-alpha 2b for 60 weeks
    • Reichard O, Foberg U, Fryden A, Mattsson L, Norkrans G, Sonnerborg A, et al. High sustained response rate and clearance of viremia after treatment with interferon-alpha 2b for 60 weeks. Hepatology 1994; 19: 280-5.
    • (1994) Hepatology , vol.19 , pp. 280-285
    • Reichard, O.1    Foberg, U.2    Fryden, A.3    Mattsson, L.4    Norkrans, G.5    Sonnerborg, A.6
  • 43
    • 0027475925 scopus 로고
    • An escalating dose regime of recombinant interferon-alpha-2A in the treatment of chronic hepatitis C
    • Bosch O, Tapia L, Quiroga JA, Carreño V. An escalating dose regime of recombinant interferon-alpha-2A in the treatment of chronic hepatitis C. J Hepatol 1993; 17: 146-9.
    • (1993) J Hepatol , vol.17 , pp. 146-149
    • Bosch, O.1    Tapia, L.2    Quiroga, J.A.3    Carreño, V.4
  • 44
    • 0027385541 scopus 로고
    • Prediction of the response of chronic hepatitis C to interferon alfa: A statistical analysis of pretreatment variables
    • Camps J, Crisóstomo S, García-Granero M, Riezu-Boj JI, Civeira MP, Prieto J. Prediction of the response of chronic hepatitis C to interferon alfa: a statistical analysis of pretreatment variables. Gut 1993; 34: 1714-7.
    • (1993) Gut , vol.34 , pp. 1714-1717
    • Camps, J.1    Crisóstomo, S.2    García-Granero, M.3    Riezu-Boj, J.I.4    Civeira, M.P.5    Prieto, J.6
  • 45
    • 0027715876 scopus 로고
    • Hepatitis C serotype and response to interferon therapy
    • Chemello L, Alberti A, Rose K, Simmonds P. Hepatitis C serotype and response to interferon therapy [Letter]. N Engl J Med 1994; 330: 143.
    • (1994) N Engl J Med , vol.330 , pp. 143
    • Chemello, L.1    Alberti, A.2    Rose, K.3    Simmonds, P.4
  • 46
    • 4244120826 scopus 로고
    • The influence of serotypes of hepatitis C virus on sustained response to alpha interferon treatment
    • Dusheiko G, Alberti A, Colombo M, Craxi A, Frost C, Prieto J, et al. The influence of serotypes of hepatitis C virus on sustained response to alpha interferon treatment [Abstract]. J Hepatol 1994; 21 (suppl 1): S17.
    • (1994) J Hepatol , vol.21 , Issue.1 SUPPL.
    • Dusheiko, G.1    Alberti, A.2    Colombo, M.3    Craxi, A.4    Frost, C.5    Prieto, J.6
  • 48
    • 0029061728 scopus 로고
    • Usefulness of simple assays for serum concentration of hepatitis C virus RNA and HCV genotype in predicting the response of patients with chronic hepatitis to interferon-α2a therapy
    • Suzuki T, Tanaka E, Matsumoto A, Urushihara A, Sodeyama T. Usefulness of simple assays for serum concentration of hepatitis C virus RNA and HCV genotype in predicting the response of patients with chronic hepatitis to interferon-α2a therapy. J Med Virol 1995; 46: 162-8.
    • (1995) J Med Virol , vol.46 , pp. 162-168
    • Suzuki, T.1    Tanaka, E.2    Matsumoto, A.3    Urushihara, A.4    Sodeyama, T.5
  • 49
    • 0028241378 scopus 로고
    • Quantitative detection of hepatitis C virus (HCV) RNA by a solid-phase signal amplification method: Definition of optimal conditions for specimen collection and clinical application in interferon treated patients
    • Davis GL, Lau JY, Urdea MS, Neuwald PD, Wilber JC, Lindsay K, et al. Quantitative detection of hepatitis C virus (HCV) RNA by a solid-phase signal amplification method: definition of optimal conditions for specimen collection and clinical application in interferon treated patients. Hepatology 1994; 19: 1337-41.
    • (1994) Hepatology , vol.19 , pp. 1337-1341
    • Davis, G.L.1    Lau, J.Y.2    Urdea, M.S.3    Neuwald, P.D.4    Wilber, J.C.5    Lindsay, K.6
  • 50
    • 9244231689 scopus 로고
    • Evaluacion de la replicación del virus de la hepatitis C (VHC), su relación con el genotipo viral, la gravedad de la enfermedad y la respuesta al tratamiento
    • Olmedo E, Forns X, Ampurdanés S, Maluenda MD, López-labrador FX, Costa J, et al. Evaluacion de la replicación del virus de la hepatitis C (VHC), su relación con el genotipo viral, la gravedad de la enfermedad y la respuesta al tratamiento [Abstract]. Gastroenterol Hepatol 1995; 18: 266.
    • (1995) Gastroenterol Hepatol , vol.18 , pp. 266
    • Olmedo, E.1    Forns, X.2    Ampurdanés, S.3    Maluenda, M.D.4    López-labrador, F.X.5    Costa, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.