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Volumn 43, Issue 12, 1996, Pages 1544-1556

Treatment of Chronic Hepatitis C with a-Interferon: An Analysis of the Literature

Author keywords

Antiviral therapy; Hepatitis C virus; Interferon; Liver cirrhosis; Meta analysis

Indexed keywords

ALANINE AMINOTRANSFERASE; LYMPHOBLAST INTERFERON; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT ALPHA2B INTERFERON; RECOMBINANT ALPHA2C INTERFERON;

EID: 0030458737     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (30)

References (73)
  • 2
    • 0024816253 scopus 로고
    • Mechanisms of action of interferon
    • Peters M. Mechanisms of action of interferon. Semin Liver Dis 1989;9:5-9.
    • (1989) Semin Liver Dis , vol.9 , pp. 5-9
    • Peters, M.1
  • 3
    • 0025915674 scopus 로고
    • Interferon for non-A, non-B chronic hepatitis
    • Tine F, Magrin S, Craxi A, and Pagliaro L. Interferon for non-A, non-B chronic hepatitis. J Hepatol 1991; 13:192-99.
    • (1991) J Hepatol , vol.13 , pp. 192-199
    • Tine, F.1    Magrin, S.2    Craxi, A.3    Pagliaro, L.4
  • 4
    • 0023124103 scopus 로고
    • Meta-analysis of randomized clinical trials
    • Sacks HS, Berner J, Reitman D, et al. Meta-analysis of randomized clinical trials. N Engl J Med 1987;316:450-55.
    • (1987) N Engl J Med , vol.316 , pp. 450-455
    • Sacks, H.S.1    Berner, J.2    Reitman, D.3
  • 6
    • 0027214879 scopus 로고
    • Benelux multicentre trial of alpha interferon treatment for chronic hepatitis C: Standard vs high dose treatment monitored by biochemical and virological markers (interim analysis)
    • Brower JF and the Benelux Multicentre Trial Study Group. Benelux multicentre trial of alpha interferon treatment for chronic hepatitis C: standard vs high dose treatment monitored by biochemical and virological markers (interim analysis). Gut 1993; 17:S119-S120.
    • (1993) Gut , vol.17
    • Brower, J.F.1
  • 7
    • 0027475925 scopus 로고
    • An escalating dose regime of recombinant interferon α-2a in the treatment of chronic hepatitis C
    • Bosch O, Tapia L, Quiroga JA, Carreno V. An escalating dose regime of recombinant interferon α-2a in the treatment of chronic hepatitis C. J Hepatol 1993; 17:146-149.
    • (1993) J Hepatol , vol.17 , pp. 146-149
    • Bosch, O.1    Tapia, L.2    Quiroga, J.A.3    Carreno, V.4
  • 8
    • 24844447384 scopus 로고
    • Efficacy of different treatments with α interferon in chronic sporadic hepatitis C
    • Brillanti S, Ricci P, Paparo GF, Miglioli M, Barbara L. Efficacy of different treatments with α interferon in chronic sporadic hepatitis C. Hepatology 1991; 14:A200.
    • (1991) Hepatology , vol.14
    • Brillanti, S.1    Ricci, P.2    Paparo, G.F.3    Miglioli, M.4    Barbara, L.5
  • 9
    • 24844453344 scopus 로고
    • Effectiveness of long-term lymphoblastoid interferon treatment in chronic hepatitis C (CHC)
    • Camps J, Castilla A, Riezu-Boj JI. Effectiveness of long-term lymphoblastoid interferon treatment in chronic hepatitis C (CHC). J Hepatol 1990;11:S15.
    • (1990) J Hepatol , vol.11
    • Camps, J.1    Castilla, A.2    Riezu-Boj, J.I.3
  • 10
    • 0027385541 scopus 로고
    • Prediction of the response of chronic hepatitis C to interferon a: A statistical analysis of pretreatment variables
    • Camps J, Crisostomo S, Garcua-Granero M, Riezu-Boj JI, Civeira MP, Prieto J. Prediction of the response of chronic hepatitis C to interferon a: a statistical analysis of pretreatment variables. Gut 1993; 34:1714-1717.
    • (1993) Gut , vol.34 , pp. 1714-1717
    • Camps, J.1    Crisostomo, S.2    Garcua-Granero, M.3    Riezu-Boj, J.I.4    Civeira, M.P.5    Prieto, J.6
  • 11
    • 0027322285 scopus 로고
    • Randomised trial of lymphoblastoid α interferon in chronic hepatitis C: Effects on inflammation, fibrogenesis and viremia
    • Camps J, Castilla A, Ruiz J, Civeira MP, Prieto J. Randomised trial of lymphoblastoid α interferon in chronic hepatitis C: Effects on inflammation, fibrogenesis and viremia. J Hepatol 1993;17:390-396.
    • (1993) J Hepatol , vol.17 , pp. 390-396
    • Camps, J.1    Castilla, A.2    Ruiz, J.3    Civeira, M.P.4    Prieto, J.5
  • 12
    • 1542628587 scopus 로고
    • A double blind placebo controlled trail of treatment of chronic hepatitis NANB with recombinant interferon α-2a
    • Carreño V, Trepo C, Gerken G, Barcena A, Bar Meir S, Desmet V, Ryff JC. A double blind placebo controlled trail of treatment of chronic hepatitis NANB with recombinant interferon α-2a. Hepatology 1992; 16:A75.
    • (1992) Hepatology , vol.16
    • Carreño, V.1    Trepo, C.2    Gerken, G.3    Barcena, A.4    Bar Meir, S.5    Desmet, V.6    Ryff, J.C.7
  • 13
    • 0027473444 scopus 로고
    • Lymphoblastoid α-interferon for chronic hepatitis C: A randomized controlled study
    • Castilla A, Camps-Bansell J, Civeira MP, Prieto J. Lymphoblastoid α-interferon for chronic hepatitis C: a randomized controlled study. Am J Gastroenterol 1993; 88: 233-239.
    • (1993) Am J Gastroenterol , vol.88 , pp. 233-239
    • Castilla, A.1    Camps-Bansell, J.2    Civeira, M.P.3    Prieto, J.4
  • 14
    • 0025768539 scopus 로고
    • Comparison of 1 or 3 MU of interferon alpha-2b and placebo in patients with chronic non-A non-B hepatitis
    • Causse X, Godinot H, Chevalier M, Chossegros P, Zoulim F, Ouzan D, et al. Comparison of 1 or 3 MU of interferon alpha-2b and placebo in patients with chronic non-A non-B hepatitis. Gastroenterology 1991;101:497-502.
    • (1991) Gastroenterology , vol.101 , pp. 497-502
    • Causse, X.1    Godinot, H.2    Chevalier, M.3    Chossegros, P.4    Zoulim, F.5    Ouzan, D.6
  • 15
    • 1542628589 scopus 로고
    • Relatively high dose for twelve months recombinant a interferon treatment in chronic hepatitis C: A randomized controlled study
    • Cerini R, Cozzolino G, Morante R, Lucariello A, De Rosa ML, Cacciatore F. Relatively high dose for twelve months recombinant a interferon treatment in chronic hepatitis C: a randomized controlled study. Hepatology 1991;14:A70.
    • (1991) Hepatology , vol.14
    • Cerini, R.1    Cozzolino, G.2    Morante, R.3    Lucariello, A.4    De Rosa, M.L.5    Cacciatore, F.6
  • 18
    • 1542628588 scopus 로고
    • Treatment of chronic NANB (type C) hepatitis with recombinant interferon alpha-2b. Preliminary clinical results
    • De Conca V, Mornese A, Michetti P. Treatment of chronic NANB (type C) hepatitis with recombinant interferon alpha-2b. Preliminary clinical results. Gastroenterology 1990; 98:A581.
    • (1990) Gastroenterology , vol.98
    • De Conca, V.1    Mornese, A.2    Michetti, P.3
  • 23
    • 1542628585 scopus 로고
    • Treatment of chronic non-A non-B hepatitis (NANB/H) blood related and sporadic with recombinant interferon A (IFN). Controlled, multi-centre study from Canada
    • Feinman SV, Willems B, Minuk G, Heathcote JE, Bailey R, Scully L, Steinbrecher U, et al. Treatment of chronic non-A non-B hepatitis (NANB/H) blood related and sporadic with recombinant interferon A (IFN). Controlled, multi-centre study from Canada. Hepatology 1991;14:71A.
    • (1991) Hepatology , vol.14
    • Feinman, S.V.1    Willems, B.2    Minuk, G.3    Heathcote, J.E.4    Bailey, R.5    Scully, L.6    Steinbrecher, U.7
  • 25
    • 1542733852 scopus 로고
    • Recombinant interferon alpha-2b in the treatment of chronic non-A non-B (NANB) hepatitis
    • Gold Coast Australia
    • Findor J, Perez V, Tanno H. Recombinant interferon alpha-2b in the treatment of chronic non-A non-B (NANB) hepatitis. IASL Meeting Abstract Book. Gold Coast Australia 1990:76.
    • (1990) IASL Meeting Abstract Book , pp. 76
    • Findor, J.1    Perez, V.2    Tanno, H.3
  • 27
    • 0025671752 scopus 로고
    • Prolonged treatment (18 months) of chronic hepatitis C with recombinant alpha-interferon in comparison with a control group
    • Gomez-Rubio M, Porres JC, Castillo J, Quiroga JA, Moreno A, Carreno V. Prolonged treatment (18 months) of chronic hepatitis C with recombinant alpha-interferon in comparison with a control group. J Hepatol 1990;11:S63-S67.
    • (1990) J Hepatol , vol.11
    • Gomez-Rubio, M.1    Porres, J.C.2    Castillo, J.3    Quiroga, J.A.4    Moreno, A.5    Carreno, V.6
  • 28
    • 0344330769 scopus 로고
    • One year therapy of non-A non-B/C chronic hepatitis with recombinant alpha-2a-interferon or lymphoblastoid alphα-interferon
    • Ideo G, Bellati G, Pedraglio E. One year therapy of non-A non-B/C chronic hepatitis with recombinant alpha-2a-interferon or lymphoblastoid alphα-interferon. J Hepatol 1990;11: S31.
    • (1990) J Hepatol , vol.11
    • Ideo, G.1    Bellati, G.2    Pedraglio, E.3
  • 29
    • 0024571564 scopus 로고
    • Randomized controlled trial of interferon alpha (lymphoblastoid interferon) in chronic non-A non-B hepatitis
    • Jacyna MR, Brooks MG, Loke RHT, Main J, Murray-Lyon IM, Thomas HC. Randomized controlled trial of interferon alpha (lymphoblastoid interferon) in chronic non-A non-B hepatitis. Br Med J 1989;298:80-82.
    • (1989) Br Med J , vol.298 , pp. 80-82
    • Jacyna, M.R.1    Brooks, M.G.2    Rht, L.3    Main, J.4    Murray-Lyon, I.M.5    Thomas, H.C.6
  • 30
    • 0028008814 scopus 로고
    • Comparative efficacy of interferon a in cirrhotic and noncirrhotic patients with non-A, non-B hepatitis
    • Jouet P, Roudot-Thoroval F, Dhumeaux D, Metreau JM, Le groupe francais pour l'itude du traitement des hipatites chroniques NANB/C. Comparative efficacy of interferon a in cirrhotic and noncirrhotic patients with non-A, non-B hepatitis. Gastroenterology 1994;106:686-690.
    • (1994) Gastroenterology , vol.106 , pp. 686-690
    • Jouet, P.1    Roudot-Thoroval, F.2    Dhumeaux, D.3    Metreau, J.M.4
  • 31
    • 0027534328 scopus 로고
    • A randomized, controlled trial of weekly administration of lymphoblastoid interferon in patients with chronic hepatitis C
    • Kagawa T, Morizane T, Saito H, Miyaguchi S, Tsunematsu S, Tada S, Guevara FM, et al. A randomized, controlled trial of weekly administration of lymphoblastoid interferon in patients with chronic hepatitis C. J Hepatol 1993;17:91-96.
    • (1993) J Hepatol , vol.17 , pp. 91-96
    • Kagawa, T.1    Morizane, T.2    Saito, H.3    Miyaguchi, S.4    Tsunematsu, S.5    Tada, S.6    Guevara, F.M.7
  • 34
    • 1542419176 scopus 로고
    • Randomized controlled trial of interferon alpha-2a for chronic active hepatitis non-A non-B: Biochemical and histological evidence of remission
    • Lin R, Shoeman M, Craig P, et al. Randomized controlled trial of interferon alpha-2a for chronic active hepatitis non-A non-B: biochemical and histological evidence of remission. Hepatology 1989;10:A646.
    • (1989) Hepatology , vol.10
    • Lin, R.1    Shoeman, M.2    Craig, P.3
  • 35
    • 24844443081 scopus 로고
    • Alpha-interferon 2b in the treatment of chronic active hepatitis c: Interim report of the first multicentre australian trial
    • Lin R, Zimmermann M, Roach E, Farell G. Alpha-interferon 2b in the treatment of chronic active hepatitis c: interim report of the first multicentre australian trial. Hepatology 1992;16:A75.
    • (1992) Hepatology , vol.16
    • Lin, R.1    Zimmermann, M.2    Roach, E.3    Farell, G.4
  • 36
    • 0025732689 scopus 로고
    • Recombinant human alpha-interferon in patients with chronic non-A, non-B hepatitis: A multicenter randomized controlled trial from France
    • Marcellin P, Boyer N, Giostra E, Degott C, Couroche AM, Degos F, Coppere H, et al. Recombinant human alpha-interferon in patients with chronic non-A, non-B hepatitis: a multicenter randomized controlled trial from France. Hepatology 1991;13:393-397.
    • (1991) Hepatology , vol.13 , pp. 393-397
    • Marcellin, P.1    Boyer, N.2    Giostra, E.3    Degott, C.4    Couroche, A.M.5    Degos, F.6    Coppere, H.7
  • 37
    • 1542733850 scopus 로고
    • Absence of efficacy of an increasing dosage schedule of the response rate during and after recombinant alpha interferon therapy in chronic hepatitis C
    • Marcellin P, Pouteau M, Boyer N, Degos F, Martinot-Peignoux M, Degott C, Erlinger S. Absence of efficacy of an increasing dosage schedule of the response rate during and after recombinant alpha interferon therapy in chronic hepatitis C. Hepatology 1991; 14:71A.
    • (1991) Hepatology , vol.14
    • Marcellin, P.1    Pouteau, M.2    Boyer, N.3    Degos, F.4    Martinot-Peignoux, M.5    Degott, C.6    Erlinger, S.7
  • 38
    • 1542628581 scopus 로고
    • Preliminary results of a randomized controlled trial with human lymphoblastoid interferon in chronic non-A non-B hepatitis
    • Mazzella G, Villanova N, Bazzoli F. Preliminary results of a randomized controlled trial with human lymphoblastoid interferon in chronic non-A non-B hepatitis. Ital J Gastroenterol 1990;22:175.
    • (1990) Ital J Gastroenterol , vol.22 , pp. 175
    • Mazzella, G.1    Villanova, N.2    Bazzoli, F.3
  • 39
    • 0027263049 scopus 로고
    • Results of long term interferon treatment in non A non B/C chronic active hepatitis
    • Mitreau JM, The French Group for the study of NANB/C chronic hepatitis treatment. Results of long term interferon treatment in non A non B/C chronic active hepatitis. Gut 1993;34:S112-S113.
    • (1993) Gut , vol.34
    • Mitreau, J.M.1
  • 40
    • 1542628584 scopus 로고
    • Long-term treatment with low doses of interferon alpha-2b (rIFNa2b) in patients with chronic non-a non-B (NANB) hepatitis: Data of a multicenter randomized prospectively controlled trial
    • Müller R, Baumgarten R, Markus R, Beckh KH, Loeschke K, Stremmel W, Niederau C, Wiedmann KH, Weber P. Long-term treatment with low doses of interferon alpha-2b (rIFNa2b) in patients with chronic non-a non-B (NANB) hepatitis: data of a multicenter randomized prospectively controlled trial. J Hepatol 1990;11:184.
    • (1990) J Hepatol , vol.11 , pp. 184
    • Müller, R.1    Baumgarten, R.2    Markus, R.3    Beckh, K.H.4    Loeschke, K.5    Stremmel, W.6    Niederau, C.7    Wiedmann, K.H.8    Weber, P.9
  • 44
    • 0025668089 scopus 로고
    • Recombinant human interferon alpha-2a in community acquired non-A non-B chronic active hepatitis. Preliminary results of a randomized controlled trial
    • Realdi G, Diodati G, Bonetti P, Scaccabarozzi S, Alberti A, Ruol A. Recombinant human interferon alpha-2a in community acquired non-A non-B chronic active hepatitis. Preliminary results of a randomized controlled trial. J Hepatol 1990;11:S68-S71.
    • (1990) J Hepatol , vol.11
    • Realdi, G.1    Diodati, G.2    Bonetti, P.3    Scaccabarozzi, S.4    Alberti, A.5    Ruol, A.6
  • 45
    • 0028012650 scopus 로고
    • High sustained response rate and clearance of viremia in chronic hepatitis C after treatment with interfon alpha-2-b for 60 weeks
    • Reichard O, Foberg U, Frydin A, Mattsson L, Norkrans G, Swnnerborg A, Wejstal R, et al. High sustained response rate and clearance of viremia in chronic hepatitis C after treatment with interfon alpha-2-b for 60 weeks. Hepatology 1994;19:280-285.
    • (1994) Hepatology , vol.19 , pp. 280-285
    • Reichard, O.1    Foberg, U.2    Frydin, A.3    Mattsson, L.4    Norkrans, G.5    Swnnerborg, A.6    Wejstal, R.7
  • 46
    • 0025963882 scopus 로고
    • High doses of recombinant alpha-interferon or gamma-interferon for chronic hepatitis C: A randomized, controlled trial
    • Saez-Royuela F, Porres JC, Moreno A, Castillo I, Martinez G, Galiana F, Carreẃo V. High doses of recombinant alpha-interferon or gamma-interferon for chronic hepatitis C: a randomized, controlled trial. Hepatology 1990;13:327-331.
    • (1990) Hepatology , vol.13 , pp. 327-331
    • Saez-Royuela, F.1    Porres, J.C.2    Moreno, A.3    Castillo, I.4    Martinez, G.5    Galiana, F.6    Carreẃo, V.7
  • 49
    • 0024788732 scopus 로고
    • A randomized controlled open study of interferon alpha-2b treatment of chronic non-A non-B posttransfusion hepatitis: No correlation of outcome to presence of hepatitis C virus antibodies
    • Schvarcz R, Weiland O, Wejstal R. A randomized controlled open study of interferon alpha-2b treatment of chronic non-A non-B posttransfusion hepatitis: no correlation of outcome to presence of hepatitis C virus antibodies. Scand J Infect Dis 1989; 21:617-625.
    • (1989) Scand J Infect Dis , vol.21 , pp. 617-625
    • Schvarcz, R.1    Weiland, O.2    Wejstal, R.3
  • 50
    • 24844447127 scopus 로고
    • Response to interferon therapy predicted by changes in serum HCV-RNA titer early in treatment
    • Terrault N, Wilber J, Feinman SV. Response to interferon therapy predicted by changes in serum HCV-RNA titer early in treatment. Gastroenterology 1994; 106:A997.
    • (1994) Gastroenterology , vol.106
    • Terrault, N.1    Wilber, J.2    Feinman, S.V.3
  • 51
    • 24844452939 scopus 로고
    • Effectiveness of high dose/long term a interferon therapy in chronic hepatitis C
    • Tobias H, Sherman A, Michaud J, Tepperman L. Effectiveness of high dose/long term a interferon therapy in chronic hepatitis C. Gastroenterology 1994;106:A999.
    • (1994) Gastroenterology , vol.106
    • Tobias, H.1    Sherman, A.2    Michaud, J.3    Tepperman, L.4
  • 53
    • 1542733843 scopus 로고
    • Randomized controlled trial of recombinant alpha-2a-interferon in chronic NANB posttransfusion hepatitis
    • Tremolada F, Casarin C, Scaccabarozzi S. Randomized controlled trial of recombinant alpha-2a-interferon in chronic NANB posttransfusion hepatitis. J Hepatol 1990;11:S117.
    • (1990) J Hepatol , vol.11
    • Tremolada, F.1    Casarin, C.2    Scaccabarozzi, S.3
  • 56
    • 0025637179 scopus 로고
    • Therapy of post-transfusion non-A non-B hepatitis with interferon alpha-2b: Swedish experience
    • Weiland O, Schvarcz R, Wejstal R, Norkrans G, Fryden A. Therapy of post-transfusion non-A non-B hepatitis with interferon alpha-2b: swedish experience. J Hepatol 1990;11:S57-S62.
    • (1990) J Hepatol , vol.11
    • Weiland, O.1    Schvarcz, R.2    Wejstal, R.3    Norkrans, G.4    Fryden, A.5
  • 58
    • 0343265768 scopus 로고
    • Recombinant alpha-interferon for chronic non-A non-B hepatitis: Optimal dose and factors associated with favourable response
    • Causse X, Godinot H, Ouzan D. Recombinant alpha-interferon for chronic non-A non-B hepatitis: optimal dose and factors associated with favourable response. Hepatology 1989;10:A643.
    • (1989) Hepatology , vol.10
    • Causse, X.1    Godinot, H.2    Ouzan, D.3
  • 60
    • 1542523826 scopus 로고
    • Recombinant alpha-2α-interferon (r-IFN), lymphoblastoid alpha-interferon (l-IFN) or no treatment for non-A non-B chronic active hepatitis (CAH): A prospective randomized controlled trial
    • Idea G, Bellati G, Pedraglio E, Altieri G. Recombinant alpha-2α-interferon (r-IFN), lymphoblastoid alpha-interferon (l-IFN) or no treatment for non-A non-B chronic active hepatitis (CAH): a prospective randomized controlled trial. Hepatology 1989;10:637.
    • (1989) Hepatology , vol.10 , pp. 637
    • Idea, G.1    Bellati, G.2    Pedraglio, E.3    Altieri, G.4
  • 61
    • 24844455218 scopus 로고
    • A controlled study of lymphoblastoid interferon in chronic non-A, non-B hepatitis
    • Jacyna MR, Brooks G, Loke RHT. A controlled study of lymphoblastoid interferon in chronic non-A, non-B hepatitis. J Hepatol 1988;7:S42.
    • (1988) J Hepatol , vol.7
    • Jacyna, M.R.1    Brooks, G.2    Loke, R.H.T.3
  • 62
    • 24844457960 scopus 로고
    • Treatment of NANB/C chronic active hepatitis by alpha interferon: Comparison of response in cirrhotic and non-cirrhotic patients
    • Jouet P, Roudot-Thoroval F, Dhumeaux D, Metreau JM. Treatment of NANB/C chronic active hepatitis by alpha interferon: comparison of response in cirrhotic and non-cirrhotic patients. J Hepatol 1992; 16:S50.
    • (1992) J Hepatol , vol.16
    • Jouet, P.1    Roudot-Thoroval, F.2    Dhumeaux, D.3    Metreau, J.M.4
  • 63
    • 1542733848 scopus 로고
    • Better efficacy of high dose versus low dose recombinant interferon alpha-2b treatment in chronic non-A non-B hepatitis
    • Marcellin P, Boyer N, Giostra E, Degott C, Degos F, Coppere H, Cales P, et al. Better efficacy of high dose versus low dose recombinant interferon alpha-2b treatment in chronic non-A non-B hepatitis. Hepatology 1989;10: A646.
    • (1989) Hepatology , vol.10
    • Marcellin, P.1    Boyer, N.2    Giostra, E.3    Degott, C.4    Degos, F.5    Coppere, H.6    Cales, P.7
  • 65
    • 1542733846 scopus 로고
    • Twelve-month treatment, compared to 6-month treatment, does not improve the efficacy of alpha-interferon in NANB chronic active hepatitis
    • Mitreau JM, Calmus Y, Poupon R, Jouanolle H, Miguet JP, Brechot C, Cales P, et al. Twelve-month treatment, compared to 6-month treatment, does not improve the efficacy of alpha-interferon in NANB chronic active hepatitis. Hepatology 1991;14:A72.
    • (1991) Hepatology , vol.14
    • Mitreau, J.M.1    Calmus, Y.2    Poupon, R.3    Jouanolle, H.4    Miguet, J.P.5    Brechot, C.6    Cales, P.7
  • 66
    • 0025963882 scopus 로고
    • Treatment of chronic non-A non-B hepatitis with high doses of rIFN-alpha or rIFN-gamma
    • Saiz-Royuela F, Porres JC, Carreẃo V. Treatment of chronic non-A non-B hepatitis with high doses of rIFN-alpha or rIFN-gamma. Hepatology 1991;13:327-31.
    • (1991) Hepatology , vol.13 , pp. 327-331
    • Saiz-Royuela, F.1    Porres, J.C.2    Carreẃo, V.3
  • 68
    • 0023124103 scopus 로고
    • Meta-analysis of randomized clinical trials
    • Sachs HS, Berrier J, Reitmann D. Meta-analysis of randomized clinical trials. N Engl J Med 1987;316:450-455.
    • (1987) N Engl J Med , vol.316 , pp. 450-455
    • Sachs, H.S.1    Berrier, J.2    Reitmann, D.3
  • 71
    • 0025600371 scopus 로고
    • An empirical study of the possible relations of treatment differences to quality scores in controlled randomized clinical trials
    • Emerson JD, Burdirk E, Hoaglin DC, Mosteller F, Chalmers TC. An empirical study of the possible relations of treatment differences to quality scores in controlled randomized clinical trials. Controlled Clin Trials 1990; 11:339-352.
    • (1990) Controlled Clin Trials , vol.11 , pp. 339-352
    • Emerson, J.D.1    Burdirk, E.2    Hoaglin, D.C.3    Mosteller, F.4    Chalmers, T.C.5
  • 72
    • 0026703267 scopus 로고
    • The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients
    • Okada S, Akahane Y, Suzuki H, Okamoto H, Mishiro S. The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients. Hepatology 1992;16:619-624.
    • (1992) Hepatology , vol.16 , pp. 619-624
    • Okada, S.1    Akahane, Y.2    Suzuki, H.3    Okamoto, H.4    Mishiro, S.5
  • 73
    • 0026734297 scopus 로고
    • Detection of hepatitis C virus by polymerase chain reaction and response to interferon alpha therapy: Relationship to genotypes of hepatitis C virus
    • Yoshioka K, Kakumu S, Wakita T, Ishikawa T, Itoh Y, Takayanagi M, Higashi Y, et al. Detection of hepatitis C virus by polymerase chain reaction and response to interferon alpha therapy: relationship to genotypes of hepatitis C virus. Hepatology 1992;16: 293-299.
    • (1992) Hepatology , vol.16 , pp. 293-299
    • Yoshioka, K.1    Kakumu, S.2    Wakita, T.3    Ishikawa, T.4    Itoh, Y.5    Takayanagi, M.6    Higashi, Y.7


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