Meltrin-α, a fusion protein involved in multinucleated giant cell and osteoclast formation

Calcified Tissue International

Volumn 64, Issue 6, 1999, Pages 508-515

  Abe, E ^a   Mocharla, H ^a   Yamate, T ^a   Taguchi, Y ^a   Manolagas, S C ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Fusion; Macrophages; Meltrin; Osteoblasts; Osteoclasts

Indexed keywords

ACID PHOSPHATASE; ANTISENSE OLIGONUCLEOTIDE; CALCITRIOL; CELL PROTEIN; ISOPROTEIN; MELTRIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FUSION; CONTROLLED STUDY; GIANT CELL; LUNG ALVEOLUS MACROPHAGE; MALE; MONONUCLEAR CELL; MOUSE; MYOTUBE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; REGULATORY MECHANISM;

ADAM PROTEINS; ANIMALS; BONE MARROW CELLS; CALCITRIOL; CELL FUSION; CELLS, CULTURED; COCULTURE TECHNIQUES; DISINTEGRINS; DNA PRIMERS; GIANT CELLS; MACROPHAGES, ALVEOLAR; MALE; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; METALLOPROTEASES; MICE; MUSCLE PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; OSTEOCLASTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN;

EID: 0033017290     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900641     Document Type: Article

References (39)

1. White JM (1990) Viral and cellular membrane fusion proteins. Ann Rev Physiol 52:675-697
2. Wolfsberg TG, Primakoff P, Myles D, White JM (1995) ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease Domain: multipotential functions in cell-cell and cell-matrix interactions. J Cell Biol 131: 275-278
3. Wolfsberg TG, Straight PD, Gerena RL, Huovila A-PJ, Primakoff P. Myles DJ, White JM (1995) ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with A Disintegrin and Metalloprotease Domain. Dev Biol 169:378-383
4. Huovila A-PJ, Almeida EAC, White JM (1996) ADAMs and cell fusion. Curr Opin Cell Biol 8:692-699
5. Blobel CP, Wolfsberg TG, Turck CW, Myles DG, Primakoff P, White JM (1992) A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 359:248-252
6. Heinlein UAO, Wallat S, Senftleben A, Lemaire L (1994) Male germ cell-expressed mouse gene TAZ83 encodes a putative, cysteine-rich transmembrane protein (cyritestin) sharing homologies with snake toxins and sperm-egg fusion proteins. Dev Growth Differ 36:49-58
7. Snell WJ, White JM (1996) The molecules of mammalian fertilization. Cell 85:629-637
8. Weskamp G, Blobel CP (1994) A family of cellular proteins related to snake venom disintegrins. Proc Natl Acad Sci USA 91:2748-2751
9. Perry ACF, Jones R, Hall L (1995) A mammalian epididymal protein with remarkable sequence similarity to snake venom haemorragic peptides. Biochem J 312:239-244
10. Yagami-Hiromasa T, Sato T, Kurisaki T, Kamijo K, Nabeshima Y, Fujisawa-Sehara A (1995) A metalloprotease-disintegrin participating in myoblast fusion. Nature 377:652-656
11. Gilpin BJ, Loeche F, Mattei M-G, Engvall E, Albrechtsen R, Wewer UM (1998) A novel, secreted form of human ADAM 12 (Meltrin α) provokes myogenesis in vivo. J Biol Chem 273:157-166
12. Hunninghake GW, Garrett KC, Richardson HB, Fianton JC, Ward PA, Rennald SI, Bitterman PB, Crystal PG (1984) Pathogenesis of the granulomatous lung disease. Am Rev Respir Dis 130:476-496
13. Daniele RP, Rossman MD, Kern J, Elias JA (1986) Pathogenesis of sarcoidosis: state of the art. Chest 89:174S
14. Wesolowski G, Duong LT, Lakkakorpo PT, Nagy RM, Tezuka K-I, Tanaka H, Rodan GA, Rodan SB (1995) Isolation and characterization of highly enriched, mouse osteoclastic cells. Exp Cell Res 219:679-686
15. Takahashi N, Akatsu T, Udagawa N, Sasaki T, Yamaguchi A, Moseley JM, Martin TJ, Suda T (1988) Osteoblastic cells are involved in osteoclast formation. Endocrinology 123:2600-2602
16. Suda T, Takahashi N, Martin TJ (1995) Modulation of osteoclast differentiation: update 1995. Endocr Rev 4:266-270
17. Lacey DL, Timms E, Tan HL, Kelley MJ, Elliot R, Colombero A, Elliot G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ (1998) Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93:165-176
18. Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinoshita M, Mochizuki S-I, Tomoyasu A, Yano K, Goto M, Murakami A, Tsuda E, Morinaga T, Higashino K, Udagawa N, Takahashi N, Suda T (1998) Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 95:3597-3602
19. Kittler ELJ, McGrath H, Temeles D, Crittenden RB, Kister VK, Quesenberry PG (1992) Biological significance of constitutive and subliminal growth factor production by bone marrow stroma. Blood 79:3168-3178
20. 3 promotes fusion of alveolar macrophages both by a direct mechanism and by a spleen cell-mediated indirect mechanism. Proc Natl Acad Sci USA 80:5583-5587
21. Abe E, Ishimi Y, Jin C-H, Hong M-H, Sato T, Suda T (1991) Granulocyte-macrophage colony-stimulating factor is a major macrophage fusion factor present in conditioned medium of concanavalin A-stimulated spleen cell cultures. J Immunol 147:1810-1815
22. Yamate T, Mocharla H, Taguchi Y, Igietseme JU, Manolagas SC, Abe E (1997) Osteopontin expression by osteoblast and osteoblast progenitors in the murine bone marrow: demonstration of its requirement for osteoclastogenesis and its increase after ovariectomy. Endocrinology 138:3047-3055
23. Lin S-C, Yamate T, Taguchi Y, Borba V, Girasole G, O'Brien CA, Bellido T, Abe E, Manolagas SC (1997) Regulation of the gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow. J Clin Invest 100:1980-1990
24. Jimi E, Nakamura I, Amano H, Taguchi Y, Tsurukai T, Tamura M, Takahashi N, Suda T (1996) Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact, Endocrinology 137:2187-2190
25. Inoue D, Reid M, Lum L, Kratzeschmar J, Weskamp G, Myung YM, Baron R, Blobel CP (1998) Cloning and initial characterization of mouse meltrin β and analysis of the expression of four metalloprotease-disintegrins in bone cells. J Biol Chem 273:4180-4187
26. McKie N, Dallas DL, Edwards T, Apperley JF, Croucher PI (1996) Cloning of a novel membrane-linked metalloproteinase from human myeloma cells. Biochem J 318:459-462
27. Dallas DJ, Edwards T, Russel RGG, Croucher PI (1996) A novel family of membrane-linked metalloproteinase-disintegrins is expressed by human osteoblast-like cells. J Bone Miner Res 11:S171
28. Loechel F, Gilpin BJ, Engvall E, Albrechtsen R, Wewer UM (1998) Human ADAM12 (meltrin alpha) is an active metalloprotease. J Biol Chem 273:16993-16997
29. Blobel CD (1997) Metalloproteinase-disintegrin links to cell adhesion and cleavage of TNFα and notch. Cell 90:589-592
30. Kratzschman J, Lum L, Blobel CP (1996) Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence. J Biol Chem 271:4593-4596
31. Inoue M, Namba N, Chappel J, Teitelbaum SL, Ross FP (1998) Granulocyte macrophage-colony stimulating factor reciprocally regulates alphav-associated integrins on murine osteoclast precursors. Mol Endocrinol 12:1955-1962
32. Horton MA, Tayler ML, Arnett TR, Helfrich MH (1991) Arggly-asp (RGD) peptides and the antivitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts. Exp Cell Res 195:368-375
33. Ross FP, Chappel J, Arvarez JI, Sander D, Butler WT, Farach-Carson MC, Minz KA, Kobey PG, Teitelbaum SL, Cheresh DA (1993) Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin αvβ3 potentiate bone resorption. J Biol Chem 268:9901-9907
34. Reinholt FP, Hultenby K, Oldberg A, Heinegard D (1990) Osteopontin - a possible anchor of osteoclasts to bone. Proc Natl Acad Sci USA 87:4473-4475
35. Kurachi T, Monta I, Murota S-I (1993) Involvement of adhesion molecules LFA-1 and ICAM-1 in osteoclast development. Biochim Biophys Acta 1178:259-266
36. Feuerbach D, Feyen JHM (1997) Expression of the cell-adhesion molecule VCAM-1 by stromal cells is necessary for osteoclastogenesis. FEBS Lett 402:21-24
37. Yoshida S, Setoguchi M, Higuchi Y, Akizuki S, Yamamoto S (1990) Molecular cloning of cDNA encoding MS2 antigen, a novel cell surface antigen strongly expressed in murine monocytic lineage. Int Immunol 2:585-591
38. Saginario C, Qian H, Vignery A (1995) Identification of an inducible surface molecule specific to fusing macrophages. Proc Natl Acad Sci USA 92:12210-12214
39. Saginario C, Beckers C, Kobayashi R-J, Ullu E, Vignery A (1996) Cloning of a cDNA coding for a putative preosteoclast fusion-related protein. J Bone Miner Res 11:S187