Placenta growth factor potential role in pregnancy

American Journal of Reproductive Immunology

Volumn 41, Issue 1, 1999, Pages 79-85

  Torry, Donald S ^a   Ahn, Henry ^a   Barnes, Eva L ^a   Torry, Ronald J ^b  

^a UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

^b METHODIST HOSPITAL   (United States)

Author keywords

Angiogenesis; Growth factors; Placenta; Review; Trophoblast

Indexed keywords

ANGIOGENIC FACTOR; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; PLACENTAL GROWTH FACTOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; CONFERENCE PAPER; HUMAN; PLACENTA; PREGNANCY; PRIORITY JOURNAL; TROPHOBLAST;

EID: 0033014889     PISSN: 10467408     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0897.1999.tb00078.x     Document Type: Conference Paper

References (64)

1. Torry RJ, Rongish BJ: Angiogenesis in the uterus: potential regulation and relation to tumor angiogenesis. Am J Reprod Immunol 1992; 27(3-4):171-179.
2. Ferrara N: The role of vascular endothelial growth factor in pathological angiogenesis. Breast Cancer Res Treat 1995; 36(2):127-137.
3. Dvorak HF, Brown LF, Detmar M, Dvorak AM: Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995; 146(5):1029-1039.
4. Melillo G, Scoccianti M, Kovesdi I, Safi J, Riccioni T, Capogrossi MC: Gene therapy for collateral vessel development. Cardiovasc Res 1997; 35(3):480-489.
5. Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, KS OS, Powell-Braxton L, Hillan KJ, Moore MW: Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996; 380(6573):439-442.
6. Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A: Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996; 380(6573):435-439.
7. Cheung CY: Vascular endothelial growth factor: Possible role in fetal development and placental function. J Soc Gynecol Invest 1997; 4(4):169-177.
8. Torry DS, Torry RJ: Angiogenesis and the expression of vascular endothelial growth factor in endometrium and placenta. Am J Reprod Immunol 1997; 37(1):21-29.
9. Maglione D. Guerriero V, Viglietto G, Delli-Bovi P, Persico MG: Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc Natl Acad Sci USA 1991; 88(20):9267-9271.
10. Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova O, Alitalo K, Del Vecchio S, Lei KJ, Chou JY, Persico MG: Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14. Oncogene 1993; 8(4):925-931.
11. Mattei MG, Borg JP, Rosnet O, Marme D, Birnbaum D: Assignment of vascular endothelial growth-factor (Vegf) and placenta growth-factor (Plgf) genes to human-chromosome 6p12-P21 and 14q24-Q31 regions, respectively. Genomics 1996; 32(1):168-169.
12. Cao Y, Ji WR, Qi P, Rosin A, Cao Y; Placenta growth factor: identification and characterization of a novel isoform generated by RNA alternative splicing. Biochem Biophysics Commun 1997; 235(3):493-498.
13. Gitay-Goren H, Soker S, Vlodavsky I, Neufeld G: The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules. J Biol Chem 1992; 267(9):6093-6098.
14. Sawano A, Takahashi T, Yamaguchi S, Aonuma M, Shibuya M: Flt-1 but not Kdr/Flk-1 tyrosine kinase is a receptor for placenta growth-factor, which is related to vascular endothelial growth-factor. Cell Growth Differ 1996; 7(2):213-221.
15. Maglione D, Guerriero V, Rambaldi M, Russo G, Persico MG: Translation of the placenta growth factor mRNA is severely affected by a small open reading frame localized in the 5′ untranslated region. Growth Factors 1993; 8(2):141-152.
16. Kodama J, Seki N, Tokumo K, Nakanishi Y, Yoshinouchi M, Kudo T: Placenta growth factor is abundantly expressed in human cervical squamous cell carcinoma. Eur J Gynaecol Oncol 1997; 18(6):508-510.
17. Khaliq A, Li XF, Shams M, Sisi P, Acevedo CA, Whittle MJ, Weich H, Ahmed A: Localisation of placenta growth factor (PlGF) in human term placenta. Growth Factors 1996; 13:243-250.
18. Vuorela P, Hatva E, Lymboussaki A, Kaipainen A, Joukov V, Persico MG, Alitalo K, Halmesmaki E: Expression of vascular endothelial growth factor and placenta growth factor in human placenta. Biol Reprod 1997; 56(2):489-494.
19. Shore VH, Wang TH, Wang CL, Torry RJ, Caudle MR, Torry DS: Vascular endothelial growth factor, placenta growth factor and their receptors in isolated human trophoblast. Placenta 1997; 18(8):657-665.
20. Kolch W, Martiny-Baron G, Kieser A, Marme D: Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis. Breast Cancer Res Treat 1995; 36(2): 139-155.
21. Viglietto G, Maglione D, Rambaldi M, Cerutti J. Romano A, Trapasso F, Fedele M, Ippolito P, Chiappetta G, Botti G, Fusco A, Persico M: Upregulation of vascular endothelial growth factor (VEGF) and downregulation of placenta growth factor (PlGF) associated with malignancy in human thyroid tumors and cell lines. Oncogene 1995; 11(8):1569-1579.
22. Levy AP, Levy NS, Goldberg MA: Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J Biol Chem 1996; 271(5):2746-2753.
23. Ikeda E, Achen MG, Breier G, Risau W: Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem 1995; 270(34): 19761-19766.
24. Damert A, Ikeda E, Risau W: Activator-protein-1 binding potentiates the hypoxia-inducible factor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells. Biochem J 1997; 327:419-423.
25. Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M: Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (fit) closely related to the fms family. Oncogene 1990; 5(4):519-524.
26. Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armallino DC, Gospodarowicz D, Bohlen P: Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 1992; 187(3):1579-1586.
27. Matthews W, Jordan CT, Gavin M, Jenkins NA. Copeland NG, Lemischka IR: A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci USA 1991; 88(20):9026-9030.
28. Kendall RL, Wang G, DiSalvo J, Thomas KA: Specificity of vascular endothelial cell growth factor receptor ligand binding domains. Biochem Biophys Res Commun 1994; 201(1):326-330.
29. Park JE, Chen HH, Winer J, Houck KA, Ferrara N: Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem 1994; 269(41):25646-25654.
30. Cao Y, Chen H, Zhou L, Chiang MK, Anand-Apte B, Weatherbee JA, Wang Y, Fang F, Flanagan JG, Tsang ML: Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR. J Biol Chem 1996; 271(6):3154-3162.
31. Terman B, Khandke L, Dougher-Vermazan M, Maglione D, Lassam NJ, Gospodarowicz D, Persico MG, Bohlen P, Eisinger M: VEGF receptor subtypes KDR and FLT1 show different sensitivities to heparin and placenta growth factor. Growth Factors 1994; 11(3):187-195.
32. DavisSmyth T, Presta LG, Ferrara N: Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor placenta growth factor receptor Flt-1 required for binding and structural stability. J Biol Chem 1998; 273(6):3216-3222.
33. Fong GH, Rossant J, Gertsenstein M, Breitman ML: Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995; 376(6535):66-70.
34. Kendall RL, Wang G, Thomas KA: Identification of a natural soluble form of the vascular endothelial growth factor receptor. FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 1996; 226(2):324-328.
35. Barleon B, Siemeister G, MartinyBaron G, Weindel K, Herzog C, Marme D: Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Res 1997; 57(23):5421-5425.
36. Migdal M, Huppertz B, Tessler S, Comforti A, Shibuya M, Reich R, Baumann H, Neufeld G: Neuropilin-1 is a placental growth factor-2 receptor. J Biol Chem 1998; 273(35):22272-22278.
37. Kaipainen A, Korhonen J, Pajusola K, Aprelikova O, Persico MG, Terman BI, Alitalo K: The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells. J Exp Med 1993; 178(6):2077-2088.
38. Charnock-Jones DS, Sharkey AM, Boocock CA, Ahmed A, Plevin R, Ferrara N, Smith SK: Vascular endothelial growth factor receptor localization and activation in human trophoblast and choriocarcinoma cells. Biol Reprod 1994; 51(3):524-530.
39. Clark DE, Smith SK, Sharkey AM, Charnockjones DS: Localization of VEGF and expression of its receptors Flt and Kdr in human placenta throughout pregnancy. Hum Reprod 1996; 11(5): 1090-1098.
40. Vuckovic M, Ponting J, Terman BI, Niketic V, Seif MW, Kumar S: Expression of the vascular endothelial growth-factor receptor, Kdr, in human placenta. J Anat 1996; 188(2):361-366.
41. Clauss M, Weich H, Breier G, Knies U, Rockl W, Waltenberger J, Risau W: The vascular endothelial growth-factor receptor Flt-1 mediates biological-activities. Implications for a functional-role of placenta growth-factor in monocyte activation and chemotaxis. J Biol Chem 1996; 271(30): 17629-17634.
42. Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D: Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996; 87(8):3336-3343.
43. Landgren E, Schiller P, Cao YH, ClaessonWelsh L: Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1. Oncogene 1998; 16(3):359-367.
44. Hauser S, Weich HA: A heparin-binding form of placenta growth factor (PlGF-2) is expressed in human umbilical vein endothelial cells and in placenta. Growth Factors 1993; 9(4):259-268.
45. Barillari G, Albonici L, Franzese O, Modesti A, Liberati F, Barillari P, Ensoli B, Manzari V, Santeusanio G: The basic residues of placenta growth factor type 2 retrieve sequestered angiogenic factors into a soluble form: Implications for tumor angiogenesis. Am J Pathol 1998; 152(5):1161-1166.
46. Reynolds LP, Killilea SD, Redmer DA: Angiogenesis in the female reproductive system. Faseb J 1992; 6(3):886-892.
47. Cao YH, Linden P, Shima D, Browne F, Folkman J: In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor vascular endothelial growth factor. J Clin Invest 1996; 98(11):2507-2511.
48. Kurz H, Wilting J, Sandau K, Christ B: Automated evaluation of angiogenic effects mediated by VEGF and PlGF homo- and heterodimers. Microvasc Res 1998; 55(1):92-102.
49. Ziehe M, Maglione D, Ribatti D, Morbidelli L, Lago CT, Battisti M, Paoletti I, Barra A, Tucci M, Parise G, Vincenti V, Granger HJ, Viglietto G, Persico MG: Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic. Lab Invest 1997; 76(4):517-531.
50. Khaliq A, Foreman D, Ahmed A, Weich H, Gregor Z, McLeod D, Boulton M: Increased expression of placenta growth factor in proliferative diabetic retinopathy. Lab Invest 1998; 78(1):109-116.
51. Birkenhager R, Schneppe B, Rockl W, Wilting J, Weich HA, McCarthy JEG: Synthesis and physiological-activity of heterodimers comprising different splice forms of vascular endothelial growth-factor and placenta growth-factor. Biochem J 1996; 316(3):703-707.
52. Takahashi A, Sasaki H, Kim SJ, Tobisu K, Kakizoe T, Tsukamoto T, Kumamoto Y, Sugimura T, Terada M: Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res 1994; 54(15):4233-4237.
53. Achen MG, Gad JM, Stacker SA, Wilks AF: Placenta growth factor and vascular endothelial growth factor are co-expressed during early embryonic development. Growth Factors 1997; 15(1):69-80.
54. Folkman J: Is tissue mass regulated by vascular endothelial cells? Prostate as the first evidence. Endocrinology 1998; 139(2):441-442.
55. Torry D, Laberrere C, McIntrye J: Uteroplacental vascular involvement in recurrent spontaneous abortion. Curr Opinion Obstet Gynecol 1998; 10(5):379-382.
56. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK: Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 1989; 161(5):1200-1204.
57. Conrad KP, Benyo DF: Placental cytokines and the pathogenesis of preeclampsia. Am J Reprod Immunol 1997; 37(3):240-249.
58. Torry DS, Wang T-H, Wang H-S, Caudle M, Torry R: Pre-eclampsia is associated with reduced serum levels of placenta growth factor. Am J Obstet Gynecol 1998. In Press.
59. Esterman A, Finlay TH, Dancis J: The effect of hypoxia on term trophoblast: hormone synthesis and release. Placenta 1996; 17(4):217-222.
60. Esterman A, Greco MA, Mitani Y, Finlay TH, IsmailBeigi F, Dancis J: The effect of hypoxia on human trophoblast in culture: Morphology, glucose transport and metabolism. Placenta 1997; 18:2-3.
61. Alsat E, Wyplosz P, Malassine A, Guibourdenche J, Porquet D, Nessmann C, Evainbrion D: Hypoxia impairs cell-fusion and differentiation process in human cytotrophoblast, in-vitro. J Cell Physiol 1996; 168(2):346-353.
62. Genbacev O, Zhou Y, Ludlow JW, Fisher SJ: Regulation of human placental development by oxygen tension. Science 1997; 277(5332):1669-1672.
63. Genbacev O, Joslin R, Damsky CH, Polliotti BM, Fisher SJ: Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia. J Clin Invest 1996; 97(2):540-550.
64. Zhou Y, Damsky CH, Chiu K, Roberts JM, Fisher SJ: Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts. J Clin Invest 1993; 91(3):950-960.