The basic residues of placenta growth factor type 2 retrieve sequestered angiogenic factors into a soluble form: Implications for tumor angiogenesis

American Journal of Pathology

Volumn 152, Issue 5, 1998, Pages 1161-1166

  Barillari, Giovanni ^a   Albonici, Loredana ^b   Franzese, Ornella ^a   Modesti, Andrea ^a   Liberati, Fabrizio ^e   Barillari, Paolo ^a,c   Ensoli, Barbara ^d   Manzari, Vittorio ^a   Santeusanio, Giuseppe ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b National Council of Research   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^e UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; PLACENTA GROWTH FACTOR 2; PROTEOHEPARAN SULFATE; UNCLASSIFIED DRUG; VASCULOTROPIN;

AMINO ACID SEQUENCE; ANGIOGENESIS; ARTICLE; CELL CULTURE; CELL SURFACE; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MEMBRANE BINDING; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL; TUMOR GROWTH;

ANGIOGENESIS INDUCING AGENTS; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX; FIBROBLAST GROWTH FACTOR 2; GROWTH SUBSTANCES; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHOKINES; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; POLYMERASE CHAIN REACTION; PREGNANCY PROTEINS; RNA, MESSENGER; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0031954222     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Folkman J, Shing Y: Angiogenesis. J Biol Chem 1992, 267:10931-10934
2. Liotta LA, Steeg PS, Stetler-Stevenson WG: Cancer metastasis and angiogenesis-an imbalance of positive and negative regulation. Cell 1991, 64:327-336
3. Groos JL, Morrison RS, Eidsvoog K, Heblin WF, Komblith PL, Dexter DL: Basic fibroblast growth factor: a potential autocrine regulator of human glioma cell growth. J Neurosci Res 1990, 27:689-696
4. Plate KH, Breier G, Weich HA and Risau W: Vascular endothelial growth factor is a potent tumor angiogenesis factor in human gliomas in vivo. Nature 1992, 359:845-849
5. Watanabe H, Nguyen M, Schizer M, Li V, Hayes DR, Sallan S, Folkman J: Basic fibroblast growth factor in human serum: a prognostic test for breast cancer. Mol Biol Cell 1992, 3:324-330
6. Kim KJ, Li B, Winer J, Armanini M, Gillet N, Phillips HS, Ferrara N: Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993, 362:841-844
7. Maret A, Galy B, Arnaud E, Bayard F, Prats H: Inhibition of fibroblast growth factor 2 expression by antisense RNA induced a loss of the transformed phenotype in a human hepatoma cell line. Cancer Res 1995, 55:5075-5079
8. Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova O, Alitalo K, Del Vecchio S, Lei KJ, Chou JY, Persico MG: Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PIGF), are transcribed from a single gene on chromosome 14. Oncogene 1993, 8:925-931
9. Houck KA, Ferrara N, Winer J, Cachianes G, Li B, Leung WD: The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol 1991, 5:1806-1814
10. Raines EW, Ross R: Compartmentalization of PDGF on extracellular binding sites dependent on exon 6-encoded sequences. J Cell Biol 1992, 116:533-543
11. Leung DW, Cachianes G, Kuang WJ, Goedell DV, Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989, 246:1306-1309
12. Baird A, Schubert D, Ling N, Guillemin R: Receptor and heparin binding domains of basic fibroblast growth factor. Proc Natl Acad Sci USA 1988, 85:2324-2328
13. Folkman J, Klagsbrun M. Sasse J, Wadzinski M, Ingber D, Vlodavsky I: A heparin-binding angiogenic protein - basic fibroblast growth factor - is stored within basement membrane. Am J Pathol 1988, 130: 393-400
14. Rifkin DB, Moscatelli D: Recent development in the biology of basic fibroblast growth factor. J Cell Biol 1989, 109:1-6
15. Knowles DM II, Tolidjian B, Marboe CC, Halper JP, Azzo W, Wang CY: A new human B-lymphocyte surface antigen (BL2) detectable by hybridoma monoclonal antibody: distribution on benign and malignant lymphoid cells. Blood 1983, 62:191-199
16. Mukai K, Rosai J, Burgdorf WHC: Localization of factor VIII-related antigen in vascular endothelial cells using an immunoperoxidase method. Am J Surg Pathol 1980, 4:273-276
17. Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, Arnheim N: Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 1985, 230:1350-1354
18. 4+ T-cells. Science 1988, 242:427-430
19. Barillari G, Buonaguro L, Fiorelli V, Hoffman J, Michaels F, Gallo RC, Ensoli B: Effects of cytokines from activated immune cells on vascular cell growth and HIV-1 gene expression: implication for AIDS-Kaposi's sarcoma pathogenesis. J Immunol 1992, 149:3727-3734
20. Collier IE, Wilhel SM, Eisen AZ, Marmer BL, Grant GA, Seltzer JL, Kronberger A, He C, Bauer EA, Goldberg GI: H-ras oncogene transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem. 1988, 263:6579-6587
21. Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, Wong-Staal F, Gallo RC: AIDS-Kaposi's sarcoma derived cells express cytokines with autocrine and paracrine growth effects. Science 1989, 243:223-226
22. Weindel K, Marme D, Weich HA: AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem Biophys Res Commun 1992, 183:1167-1174
23. Samaniego F, Markham P, Gallo RC, Ensoli B: Inflammatory cytokines induce AIDS-Kaposi's sarcoma-derived spindle cells to produce and release basic fibroblast growth factor and enhance Kaposi's sarcoma-like lesion formation in nude mice. J Immunol 1995, 154:3582-3592
24. Thompson EW, Nakamura S, Shima TH, Melchiorri A, Martin GR, Salahuddin SZ, Gallo RC, Albini A: Supernatants of AIDS-related Kaposi's sarcoma induce endothelial cell chemotaxis and invasiveness. Cancer Res 1991, 51:2670-2676
25. Rogelj SR, Weinberg A, Fanning P, Klagsbrun M: Basic fibroblast growth factor fused to a signal peptide transforms cells. Nature 1988, 331:173-175
26. Ferrara N, Winer J, Burton T, Rowland A, Siegel M, Phillips HS, Terrel T, Keller GA, Levinson AD: Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells. J Clin Invest 1993, 91:160-170
27. Czubayo F, Liaudet-Coopman EDE, Aigner A, Tuveson AT, Berchem GJ, Wellstein A: A secreted FGF-binding protein can serve as the angiogenic switch in human cancer. Nature Med 1997, 3:1137-1140