Experimental colitis increases blood-brain barrier permeability in rabbits

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 276, Issue 5 39-5, 1999, Pages

  Hathaway, Christopher A ^a   Appleyard, Caroline B ^a   Percy, William H ^a   Williams, John L ^a  

^a UNIVERSITY OF SOUTH DAKOTA   (United States)

Author keywords

Brain gut axis; Cerebral blood flow; Colitis model; Inflammatory bowel disease; Vasculature

Indexed keywords

ACETIC ACID; FLUORESCEIN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; MICROSPHERE SC 46; MICROSPHERE SN 113; TRINITROBENZENESULFONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN VASCULAR RESISTANCE; COLITIS; CONTROLLED STUDY; EXTRAVASATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; RABBIT;

EID: 0033014362     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.5.g1174     Document Type: Article

References (40)

1. Appleyard, C. B., and J. L. Wallace. Reactivity of hapten-induced colitis and its prevention by anti-inflammatory drugs. Am. J. Physiol. 269 (Gastrointest. Liver Physiol. 32): G119-G125, 1995.
2. Baba, M., R. Oishi, and K. Saeki. Enhancement of blood-brain barrier permeability to sodium fluorescein by stimulation of mu opioid receptors in mice. Naunyn Schmiedebergs Arch. Pharmacol. 337: 423-428, 1988.
3. Bell, C. J., D. G. Gall, and J. L. Wallace. Disruption of colonic electrolyte transport in experimental colitis. Am. J. Physiol. 268 (Gastrointest. Liver Physiol. 31): G622-G630, 1995.
4. Bradbury, M. W. The blood-brain barrier. Exp. Physiol. 78: 453-472, 1993.
5. Carter, L. and J. L. Wallace. Alterations in rat peripheral blood neutrophil function as a consequence of colitis. Dig. Dis. Sci. 40: 192-197, 1995.
6. Considine, R. V. and J. F. Caro. Leptin: genes, concepts and clinical perspective. Horm. Res. 46: 249-256, 1996.
7. Danzi, J. T. Extraintestinal manifestations of idiopathic inflammatory bowel disease. Arch. Intern. Med. 148: 297-302, 1988.
8. De Vries, H. E., M. C. Blom-Roosemalen, M. van Oosten, A. G. de Boer, T. J. van Berkel, D. D. Breimer, and J. Kuiper. The influence of cytokines on the integrity of the blood-brain barrier in vitro. J. Neuroimmunol. 64: 37-43, 1996.
9. Draijer, R., D. E. Atsma, A. van der Laarse, and V. W. van Hinsbergh. cGMP and nitric oxide modulate thrombin-induced endothelial permeability. Regulation via different pathways in human aortic and umbilical vein endothelial cells. Circ. Res. 76: 199-208, 1995.
10. Fenstermacher, J., P. Gross, N. Sposito, V. Acuff, S. Pettersen, and K. Gruber. Structural and functional variations in capillary systems within the brain. Ann. NY Acad. Sci. 529: 21-30, 1988.
11. Florence, G., and J. Seylaz. Rapid autoregulation of cerebral blood flow: a laser-Doppler flowmetry study. J. Cereb. Blood Flow Metab. 12: 674-680, 1992.
12. Fretland, D. J., D. Widomski, B. S., Tsai, J. M. Zemaitis, S. Levin, S. W. Djuric, R. L. Shone, and T. S. Gaginella. Effect of the leukotriene B4 receptor antagonist SC-41930 on colonic inflammation in rat, guinea pig and rabbit. J. Pharmacol. Exp. Ther. 255: 572-576, 1990.
13. Geissler, A., T. Andus, M. Roth, F. Kullmann, I. Caesar, P. Held, V. Gross, S. Feuerbach, and J. Scholmerich. Focal white-matter lesions in brain of patients with inflammatory bowel disease. Lancet 345: 897-898, 1995.
14. Gionchetti, P., M. Schiavina, M. Campieri, A. Fabiani, B. M. Cornia, A. Belluzzi, C. Brignola, P. Iannone, M. Miglioli, and L. Barbara. Bronchopulmonary involvement in ulcerative colitis. J. Clin. Gastroenterol. 12: 647-650, 1990.
15. Gobel, U., H. Theilen, and W. Kuschinsky. Congruence of total and perfused capillary network in rat brains. Circ. Res 66: 271-281, 1990.
16. Grantham, J. G., J. A. Meadows III, and G. J. Gleich. Chronic eosinophilic pneumonia. Evidence for eosinophil degranulation and release of major basic protein. Am. J. Med. 80: 89-94, 1986.
17. Heymann M. A., B. D. Payne, J. I. Hoffman, and A. M. Rudolf. Blood flow measurements with radionucleotide-labeled particles. Prog. Cardiovasc. Dis. 20: 55-79, 1977.
18. Johns, D. R. Cerebrovascular complications of inflammatory bowel disease. Am. J. Gastroenterol. 86: 367-370, 1991.
19. Kosarek, R. A. Extracolonic manifestations of inflammatory bowel disease. Am. Fam. Phys. 84: 205-211, 1987.
20. Lichtman, S. N. and R. B. Sartor. Inflammatory Bowel Disease: From Bench to Bedside. Baltimore, MD: Williams & Wilkins, 1994, p. 317-335.
21. Maeda, M., N. Watanabe, H. Neda, N. Yamauchi, T. Okamoto, H. Sasaki, Y. Tsuji, S. Akiyama, N. Tsuji, and Y. Niitsu. Serum tumor necrosis factor activity in inflammatory bowel disease. Immunopharmacol. Immunotoxicol. 14: 451-461, 1992.
22. Mahmud, N., G. S. McDonald, D. Kelleher, and D. G. Weir. Microalbuminuria correlates with intestinal histopathological grading in patients with inflammatory bowel disease. Gut 38: 99-103, 1996.
23. Mahmud, N., M. A. O'Connell, J. Stinson, M. G. Goggins, D. G. Weir, and D. Kelleher. Tumour necrosis factor-α and microalbuminuria in patients with inflammatory bowel disease. Eur. J. Gastroenterol. Hepatol. 7: 215-219, 1995.
24. Matsuda, M., K. Miyagi, N. Yanagisawa, N. Tsukada, and J. Nakayama. Effect of intracerebral injections of tumor necrosis factor and interleukin-1. Arerugi 42: 1623-1627, 1993.
25. Mayhan, W. G. and D. D. Heistad. Permeability of blood-brain barrier to various sized molecules. Am. J. Physiol. 248 (Heart Circ. Physiol. 17): H712-H718, 1985.
26. McHugh, K. J., E. Svensjo, and C. G. Persson. Exudative and absorptive permeability in different phases of an experimental colitis condition. Scand. J. Gastroenterol. 31: 900-905, 1996.
27. Moles, K. W., G. Varghese, and J. R. Hayes. Pulmonary involvement in ulcerative colitis. Br. J. Dis. Chest 82: 79-83, 1988.
28. Morris, G. P., P. L. Beck, M. S. Herridge, W. T. Depew, M. R. Szewczuk, and J. L. Wallace. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 96: 795-803, 1989.
29. Mun-Bryce, S., and G. A. Rosenberg. Gelatinase B modulates selective opening of the blood-brain barrier during inflammation. Am. J. Physiol. 274 (Regulatory Integrative Comp. Physiol. 43): R1203-R1211, 1998.
30. Neilly, P. J., K. R. Gardiner, S. J. Kirk, G. Jennings, N. H. Anderson, M. Elia, and B. J. Rowlands. Endotoxaemia and cytokine production in experimental colitis. Br. J. Surg. 82: 1479-1482, 1995.
31. Rankin, G. B., H. D. Watts, C. S. Melnyk, and M. L. Kelley, Jr. National cooperative Crohn's disease study: extraintestinal manifestations and perianal complications. Gastroenterology 77: 914-920, 1979.
32. Rapoport, S. I. Osmotic opening of the blood-brain barrier. Ann. Neurol. 24: 677-684, 1988.
33. Schalk, K. A., F. M. Faraci, J. L. Williams, D. VanOrden, and D. D. Heistad. Effect of atriopeptin on production of cerebrospinal fluid. J. Cereb. Blood Flow Metab. 12: 691-696, 1992.
34. Schlosshauer, B. The blood-brain barrier: morphology, molecules, and neurothelin. Bioessays 15: 341-346, 1993.
35. Souto, J. C., E. Martinez, M. Roca, J. Mateo, J. Pujol, D. Gonzalez, and J. Fontcuberta. Prothrombotic state and signs of endothelial lesion in plasma of patients with inflammatory bowel disease. Dig. Dis. Sci. 40: 1883-1889, 1995.
36. Talbot, R. W., J. Heppell, R. R. Dozois, and R. W. Beart, Jr. Vascular complications of inflammatory bowel disease. Mayo Clin. Proc. 61: 140-145, 1986.
37. Wallace, J. L., and C. M. Keenan. An orally active inhibitor of leukotriene synthesis accelerates healing in a rat model of colitis. Am. J. Physiol. 258 (Gastrointest. Liver Physiol. 21): G527-G534, 1990.
38. Williams, J. L., M. Shea, and S. C. Jones. Evidence that heterogeneity of cerebral blood flow does not involve vascular recruitment. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H1740-H1743, 1993.
39. Wolburg, H., J. Neuhaus, U. Kniesel, B. Krauss, E. M. Schmid, M. Ocalan, C. Farrell, and W. Risau. Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes. J. Cell Sci. 107: 1347-1357, 1994.
40. Zar, J. H. Biostatistical Analysis. Englewood Cliffs, NJ: Prentis-Hall, 1984, p. 122-139.